Chemical mechanism of homoisocitrate dehydrogenase from Saccharomyces cerevisiae

Biochemistry

Volumn 47, Issue 13, 2008, Pages 4169-4180

  Lin, Ying ^a   Volkman, Jerome ^a   Nicholas, Kenneth M ^a   Yamamoto, Takashi ^b   Eguchi, Tadashi ^b   Nimmo, Susan L ^a   West, Ann H ^a   Cook, Paul F ^a  

^a UNIVERSITY OF OKLAHOMA   (United States)

^b Tokyo Institute of Technology ^*  (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

BIOSYNTHESIS; CATALYSIS; ENZYME INHIBITION; KINETIC PARAMETERS; PH EFFECTS; PROTON TRANSFER;

CHEMICAL MECHANISM; HOMOISOCITRATE; OXIDATIVE DECARBOXYLATION; OXIDIZING AGENT; TAUTOMERIZATION;

YEAST;

CARBON 13; DEUTERIUM; HYDROXYACID; ISOCITRATE DEHYDROGENASE; ISOCITRIC ACID; ISOTOPE; OXOACID;

ACID BASE BALANCE; ARTICLE; CATALYSIS; CATALYST; CONFORMATIONAL TRANSITION; DECARBOXYLATION; DISSOCIATION CONSTANT; ENZYME KINETICS; ENZYME MECHANISM; NONHUMAN; OXIDATION KINETICS; PH; PKA; PRIORITY JOURNAL; PROTON TRANSPORT; SACCHAROMYCES CEREVISIAE; VISCOSITY;

ALCOHOL OXIDOREDUCTASES; CATALYSIS; HYDROGEN-ION CONCENTRATION; KINETICS; NUCLEAR MAGNETIC RESONANCE, BIOMOLECULAR; OXIDATION-REDUCTION; SACCHAROMYCES CEREVISIAE; SUBSTRATE SPECIFICITY;

SACCHAROMYCES CEREVISIAE;

EID: 41449105137     PISSN: 00062960     EISSN: None     Source Type: Journal    
DOI: 10.1021/bi702361j     Document Type: Article

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