Parental history of type 2 diabetes, TCF7L2 variant and lower insulin secretion are associated with incident hypertension. Data from the DESIR and RISC cohorts

Diabetologia

Volumn 56, Issue 11, 2013, Pages 2414-2423

  Bonnet, Fabrice ^a   Roussel, Ronan ^b,c   Natali, Andrea ^d   Cauchi, Stéphane ^e   Petrie, John ^f   Laville, Martine ^g   Yengo, Loïc ^e   Froguel, Philippe ^e,h   Lange, Céline ⁱ   Lantieri, Olivier ^j   Marre, Michel ^b,c,i   Balkau, Beverley ⁱ   Ferrannini, Ele ^d  

^a UNIVERSITÉ DE RENNES 1   (France)

^b BICHAT HOSPITAL   (France)

^c CENTRE DE RECHERCHE DES CORDELIERS   (France)

^d UNIVERSITY OF PISA   (Italy)

^e Institut Pasteur de Lille   (France)

^f UNIVERSITY OF GLASGOW   (United Kingdom)

^g Univ Lyon   (France)

^h HAMMERSMITH HOSPITAL   (United Kingdom)

ⁱ INSERM   (France)

^j IRSA   (France)

more..

Author keywords

Hypertension; Insulin secretion; Parental history of diabetes; TCF7L2; Type 2 diabetes

Indexed keywords

GLUCOSE; INSULIN; TRANSCRIPTION FACTOR 7 LIKE 2;

ADULT; AGED; ARTICLE; BLOOD PRESSURE MEASUREMENT; CARDIOVASCULAR DISEASE; COHORT ANALYSIS; CONTROLLED STUDY; DIET RESTRICTION; DISEASE ASSOCIATION; DISEASE SEVERITY; FAMILY HISTORY; FEMALE; GENETIC ASSOCIATION; GENETIC RISK; GENETIC VARIABILITY; GLUCOSE BLOOD LEVEL; GLUCOSE CLAMP TECHNIQUE; HIGH RISK POPULATION; HUMAN; HYPERINSULINEMIA; HYPERTENSION; INCIDENCE; INSULIN RELEASE; INSULIN RESISTANCE; INSULIN SENSITIVITY; MAJOR CLINICAL STUDY; MALE; NON INSULIN DEPENDENT DIABETES MELLITUS; OBSERVATIONAL STUDY; ORAL GLUCOSE TOLERANCE TEST; PRIORITY JOURNAL; PROSPECTIVE STUDY; TCF7L2 GENE; WAIST CIRCUMFERENCE;

ADULT; AGED; DIABETES MELLITUS, TYPE 2; FEMALE; HUMANS; HYPERTENSION; INSULIN; MALE; MIDDLE AGED; TRANSCRIPTION FACTOR 7-LIKE 2 PROTEIN;

EID: 84885866631     PISSN: 0012186X     EISSN: 14320428     Source Type: Journal    
DOI: 10.1007/s00125-013-3021-y     Document Type: Article

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