Anti-cancer effects of naturally occurring compounds through modulation of signal transduction and miRNA expression in human colon cancer cells

Journal of Nutritional Biochemistry

Volumn 24, Issue 11, 2013, Pages 1849-1858

  Kumazaki, Minami ^a   Noguchi, Shunsuke ^a   Yasui, Yuki ^a   Iwasaki, Junya ^a   Shinohara, Haruka ^a   Yamada, Nami ^a   Akao, Yukihiro ^a  

^a GIFU UNIVERSITY   (Japan)

Author keywords

Anti cancer drug; Anti cancer effect; Apoptosis; MiR 34a; Phytochemicals; Resveratrol

Indexed keywords

ALPHA MANGOSTIN; ANTINEOPLASTIC AGENT; EPIGALLOCATECHIN GALLATE; FLUOROURACIL; MICRORNA; MITOGEN ACTIVATED PROTEIN KINASE; MITOGEN ACTIVATED PROTEIN KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE 3; PHOSPHATIDYLINOSITOL 3 KINASE; PROTEIN KINASE B; RESVERATROL; UNCLASSIFIED DRUG;

ANTINEOPLASTIC ACTIVITY; APOPTOSIS; ARTICLE; CANCER CELL; CANCER INHIBITION; COLON CANCER; CONTROLLED STUDY; GENE EXPRESSION; HUMAN; HUMAN CELL; SIGNAL TRANSDUCTION;

ANTI-CANCER DRUG; ANTI-CANCER EFFECT; APOPTOSIS; MIR-34A; PHYTOCHEMICALS; RESVERATROL;

ANTINEOPLASTIC AGENTS; APOPTOSIS; CATECHIN; CELL LINE, TUMOR; COLONIC NEOPLASMS; DRUG RESISTANCE, NEOPLASM; HUMANS; MICRORNAS; MITOGEN-ACTIVATED PROTEIN KINASE 1; MITOGEN-ACTIVATED PROTEIN KINASE 3; PHOSPHATIDYLINOSITOL 3-KINASES; SIGNAL TRANSDUCTION; STILBENES; XANTHONES;

EID: 84885842225     PISSN: 09552863     EISSN: 18734847     Source Type: Journal    
DOI: 10.1016/j.jnutbio.2013.04.006     Document Type: Article

References (38)

1. Block G., Patterson B., Subar A. Fruit, vegetables, and cancer prevention: a review of the epidemiological evidence. Nutr Cancer 1992, 18(1):1-29.
2. Sun J., Chu Y.F., Wu X., Liu R.H. Antioxidant and antiproliferative activities of common fruits. J Agric Food Chem 2002, 50(25):7449-7454.
3. Doll R., Peto R. The causes of cancer: quantitative estimates of avoidable risks of cancer in the United States today. J Natl Cancer Inst 1981, 66(6):1191-1308.
4. Galati G., Teng S., Moridani M.Y., Chan T.S., O'Brien P.J. Cancer chemoprevention and apoptosis mechanisms induced by dietary polyphenolics. Drug Metabol Drug Interact 2000, 17(1-4):311-349.
5. Li W., Mei X., Tu Y.Y. Effects of tea polyphenols and their polymers on MAPK signaling pathways in cancer research. Mini Rev Med Chem 2012, 12(2):120-126.
6. Whitlock N.C., Baek S.J. The anticancer effects of resveratrol: modulation of transcription factors. Nutr Cancer 2012, 64(4):493-502.
7. Jankun J., Selman S.H., Swiercz R., Skrzypczak-Jankun E. Why drinking green tea could prevent cancer. Nature 1997, 387(6633):561.
8. Sah J.F., Balasubramanian S., Eckert R.L., Rorke E.A. Epigallocatechin-3-gallate inhibits epidermal growth factor receptor signaling pathway. Evidence for direct inhibition of ERK1/2 and AKT kinases. J Biol Chem 2004, 279(13):12755-12762.
9. Shimizu M., Fukutomi Y., Ninomiya M., Nagura K., Kato T., Araki H., et al. Green tea extracts for the prevention of metachronous colorectal adenomas: a pilot study. Cancer Epidemiol Biomarkers Prev 2008, 17(11):3020-3025.
10. Jang M., Cai L., Udeani G.O., Slowing K.V., Thomas C.F., Beecher C.W., et al. Cancer chemopreventive activity of resveratrol, a natural product derived from grapes. Science 1997, 275(5297):218-220.
11. Aggarwal B.B., Bhardwaj A., Aggarwal R.S., Seeram N.P., Shishodia S., Takada Y. Role of resveratrol in prevention and therapy of cancer: preclinical and clinical studies. Anticancer Res 2004, 24(5A):2783-2840.
12. Liu B.L., Zhang X., Zhang W., Zhen H.N. New enlightenment of French Paradox: resveratrol's potential for cancer chemoprevention and anti-cancer therapy. Cancer Biol Ther 2007, 6(12):1833-1836.
13. Santandreu F.M., Valle A., Oliver J., Roca P. Resveratrol potentiates the cytotoxic oxidative stress induced by chemotherapy in human colon cancer cells. Cell Physiol Biochem 2011, 28(2):219-228.
14. Tili E., Michaille J.J. Resveratrol, microRNAs, inflammation, and cancer. J Nucleic Acids 2011, 2011:102431.
15. Akao Y., Nakagawa Y., Iinuma M., Nozawa Y. Anti-cancer effects of xanthones from pericarps of mangosteen. Int J Mol Sci 2008, 9(3):355-370.
16. Matsumoto K., Akao Y., Kobayashi E., Ohguchi K., Ito T., Tanaka T., et al. Induction of apoptosis by xanthones from mangosteen in human leukemia cell lines. J Nat Prod 2003, 66(8):1124-1127.
17. Nakagawa Y., Iinuma M., Naoe T., Nozawa Y., Akao Y. Characterized mechanism of alpha-mangostin-induced cell death: caspase-independent apoptosis with release of endonuclease-G from mitochondria and increased miR-143 expression in human colorectal cancer DLD-1 cells. Bioorg Med Chem 2007, 15(16):5620-5628.
18. Adams L.S., Phung S., Yee N., Seeram N.P., Li L., Chen S. Blueberry phytochemicals inhibit growth and metastatic potential of MDA-MB-231 breast cancer cells through modulation of the phosphatidylinositol 3-kinase pathway. Cancer Res 2010, 70(9):3594-3605.
19. Ouyang L., Shi Z., Zhao S., Wang F.T., Zhou T.T., Liu B., et al. Programmed cell death pathways in cancer: a review of apoptosis, autophagy and programmed necrosis. Cell Prolif 2012, 45(6):487-498.
20. Saito Y., Saito H. MicroRNAs in cancers and neurodegenerative disorders. Front Genet 2012, 3:194.
21. Sanoff H.K., Carpenter W.R., Freburger J., Li L., Chen K., Zullig L.L., et al. Comparison of adverse events during 5-fluorouracil versus 5-fluorouracil/oxaliplatin adjuvant chemotherapy for stage III colon cancer: a population-based analysis. Cancer 2012, 118(17):4309-4320.
22. Gravalos C., Garcia-Escobar I., Garcia-Alfonso P., Cassinello J., Malon D., Carrato A. Adjuvant chemotherapy for stages II, III and IV of colon cancer. Clin Transl Oncol 2009, 11(8):526-533.
23. Ballarino M., Jobert L., Dembele D., de la Grange P., Auboeuf D., Tora L. TAF15 is important for cellular proliferation and regulates the expression of a subset of cell cycle genes through miRNAs. Oncogene 2012, Epub ahead of print; http://dx.doi.org/10.1038/onc.2012.490.
24. He M., Wang Q.Y., Yin Q.Q., Tang J., Lu Y., Zhou C.X., et al. HIF-1alpha downregulates miR-17/20a directly targeting p21 and STAT3: a role in myeloid leukemic cell differentiation. Cell Death Differ 2013, 20(3):408-418.
25. Akao Y., Seki N., Nakagawa Y., Yi H., Matsumoto K., Ito Y., et al. A highly bioactive lignophenol derivative from bamboo lignin exhibits a potent activity to suppress apoptosis induced by oxidative stress in human neuroblastoma SH-SY5Y cells. Bioorg Med Chem 2004, 12(18):4791-4801.
26. Akao Y., Nakagawa Y., Hirata I., Iio A., Itoh T., Kojima K., et al. Role of anti-oncomirs miR-143 and -145 in human colorectal tumors. Cancer Gene Ther 2010, 17(6):398-408.
27. Straetemans R., O'Brien T., Wouters L., Van Dun J., Janicot M., Bijnens L., et al. Design and analysis of drug combination experiments. Biom J 2005, 47(3):299-308.
28. Akao Y., Noguchi S., Iio A., Kojima K., Takagi T., Naoe T. Dysregulation of microRNA-34a expression causes drug-resistance to 5-FU in human colon cancer DLD-1 cells. Cancer Lett 2011, 300(2):197-204.
29. Siddiqui I.A., Adhami V.M., Afaq F., Ahmad N., Mukhtar H. Modulation of phosphatidylinositol-3-kinase/protein kinase B- and mitogen-activated protein kinase: pathways by tea polyphenols in human prostate cancer cells. J Cell Biochem 2004, 91(2):232-242.
30. Izzotti A., Cartiglia C., Steele V.E., De Flora S. MicroRNAs as targets for dietary and pharmacological inhibitors of mutagenesis and carcinogenesis. Mutat Res 2012, 751(2):287-303.
31. Hagiwara K., Kosaka N., Yoshioka Y., Takahashi R.U., Takeshita F., Ochiya T. Stilbene derivatives promote Ago2-dependent tumour-suppressive microRNA activity. Sci Rep 2012, 2:314.
32. Milenkovic D., Deval C., Gouranton E., Landrier J.F., Scalbert A., Morand C., et al. Modulation of miRNA expression by dietary polyphenols in apoE deficient mice: a new mechanism of the action of polyphenols. PLoS One 2012, 7(1):e29837.
33. Lancon A., Kaminski J., Tili E., Michaille J.J., Latruffe N. Control of microRNA expression as a new way for resveratrol to deliver its beneficial effects. J Agric Food Chem 2012, 60(36):8783-8789.
34. Welch C., Chen Y., Stallings R.L. MicroRNA-34a functions as a potential tumor suppressor by inducing apoptosis in neuroblastoma cells. Oncogene 2007, 26(34):5017-5022.
35. Stevens C., La Thangue N.B. E2F and cell cycle control: a double-edged sword. Arch Biochem Biophys 2003, 412(2):157-169.
36. Martinez L.A., Goluszko E., Chen H.Z., Leone G., Post S., Lozano G., et al. E2F3 is a mediator of DNA damage-induced apoptosis. Mol Cell Biol 2010, 30(2):524-536.
37. Bashari D., Hacohen D., Ginsberg D. JNK activation is regulated by E2F and promotes E2F1-induced apoptosis. Cell Signal 2011, 23(1):65-70.
38. Raver-Shapira N., Marciano E., Meiri E., Spector Y., Rosenfeld N., Moskovits N., et al. Transcriptional activation of miR-34a contributes to p53-mediated apoptosis. Mol Cell 2007, 26(5):731-743.