The novel chemokine receptor, G-protein-coupled receptor 75, is expressed by islets and is coupled to stimulation of insulin secretion and improved glucose homeostasis

Diabetologia

Volumn 56, Issue 11, 2013, Pages 2467-2476

  Liu, Bo ^a   Hassan, Zoheb ^a   Amisten, Stefan ^a   King, Aileen J ^a   Bowe, James E ^a   Huang, Guo Cai ^a   Jones, Peter M ^a   Persaud, Shanta J ^a  

^a School of Medicine   (United Kingdom)

Author keywords

Beta cell; Chemokine (C C motif) ligand 5; GPR75; Insulin secretion; Intracellular calcium; Type 2 diabetes

Indexed keywords

CALCIUM; CHEMOKINE RECEPTOR CCR1; CHEMOKINE RECEPTOR CCR3; CHEMOKINE RECEPTOR CCR5; G PROTEIN COUPLED RECEPTOR; G PROTEIN COUPLED RECEPTOR 75; MESSENGER RNA; PHOSPHOLIPASE C; RANTES; SMALL INTERFERING RNA; UNCLASSIFIED DRUG;

ADULT; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CALCIUM CELL LEVEL; CELLULAR DISTRIBUTION; CONTROLLED STUDY; DOWN REGULATION; GENE EXPRESSION; GLUCOSE HOMEOSTASIS; GLUCOSE TOLERANCE; HUMAN; HUMAN TISSUE; HYPERGLYCEMIA; IMMUNOHISTOCHEMISTRY; IN VIVO STUDY; INSULIN RELEASE; INSULIN RESISTANCE; INSULIN SENSITIVITY; MALE; MICROFLUOROMETRY; MOUSE; NONHUMAN; OBESITY; PANCREAS ISLET; PANCREAS ISLET BETA CELL; PRIORITY JOURNAL; RADIOIMMUNOASSAY; WESTERN BLOTTING;

ANIMALS; CHEMOKINE CCL5; GLUCOSE; HOMEOSTASIS; HUMANS; IMMUNOHISTOCHEMISTRY; INSULIN; ISLETS OF LANGERHANS; MALE; MICE; MICE, INBRED ICR; RECEPTORS, G-PROTEIN-COUPLED; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION;

EID: 84885832858     PISSN: 0012186X     EISSN: 14320428     Source Type: Journal    
DOI: 10.1007/s00125-013-3022-x     Document Type: Article

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