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Volumn 1, Issue 3, 2012, Pages 298-305

Development of immune memory to glial brain tumors after tumor regression induced by immunotherapeutic toll-like receptor 7/8 activation

Author keywords

Brain tumor; Glioma; Immunotherapy; TLR agonist

Indexed keywords

CYCLOPHOSPHAMIDE; RESIQUIMOD;

EID: 84885819087     PISSN: 21624011     EISSN: 2162402X     Source Type: Journal    
DOI: 10.4161/onci.19068     Document Type: Article
Times cited : (18)

References (42)
  • 1
    • 33749319703 scopus 로고    scopus 로고
    • Type, density, and location of immune cells within human colorectal tumors predict clinical outcome
    • Galon J, Costes A, Sanchez-Cabo F, Kirilovsky A, Mlecnik B, Lagorce-Pages C, et al. Type, density, and location of immune cells within human colorectal tumors predict clinical outcome. Science 2006; 313: 1960-4; http://dx.doi.org/10.1126/science.1129139
    • (2006) Science , vol.313 , pp. 1960-1964
    • Galon, J.1    Costes, A.2    Sanchez-Cabo, F.3    Kirilovsky, A.4    Mlecnik, B.5    Lagorce-Pages, C.6
  • 2
    • 0032529466 scopus 로고    scopus 로고
    • CD8+ T cells infiltrated within cancer cell nests as a prognostic factor in human colorectal cancer
    • Naito Y, Saito K, Shiiba K, Ohuchi A, Saigenji K, Nagura H, et al. CD8+ T cells infiltrated within cancer cell nests as a prognostic factor in human colorectal cancer. Cancer Res 1998; 58:3491-4;
    • (1998) Cancer Res , vol.58 , pp. 3491-3494
    • Naito, Y.1    Saito, K.2    Shiiba, K.3    Ohuchi, A.4    Saigenji, K.5    Nagura, H.6
  • 4
    • 0035394233 scopus 로고    scopus 로고
    • Proliferative activity of intratumoral CD8(+) T-lymphocytes as a prognostic factor in human renal cell carcinoma: clinicopathologic demonstration of antitumor immunity
    • Nakano O, Sato M, Naito Y, Suzuki K, Orikasa S, Aizawa M, et al. Proliferative activity of intratumoral CD8(+) T-lymphocytes as a prognostic factor in human renal cell carcinoma: clinicopathologic demonstration of antitumor immunity. Cancer Res 2001; 61:5132-6;
    • (2001) Cancer Res , vol.61 , pp. 5132-5136
    • Nakano, O.1    Sato, M.2    Naito, Y.3    Suzuki, K.4    Orikasa, S.5    Aizawa, M.6
  • 5
    • 0028032388 scopus 로고
    • Histological grade, perineural infiltration, tumourinfiltrating lymphocytes and apoptosis as determinants of long-term prognosis in prostatic adenocarcinoma
    • Vesalainen S, Lipponen P, Talja M, Syrjanen K. Histological grade, perineural infiltration, tumourinfiltrating lymphocytes and apoptosis as determinants of long-term prognosis in prostatic adenocarcinoma. Eur J Cancer 1994; 30:1797-803; http://dx.doi.org/10.1016/0959-8049(94)E0159-2
    • (1994) Eur J Cancer , vol.30 , pp. 1797-1803
    • Vesalainen, S.1    Lipponen, P.2    Talja, M.3    Syrjanen, K.4
  • 6
    • 0030659077 scopus 로고    scopus 로고
    • Study of tumor infiltrating lymphocytes and transforming growth factor-beta as prognostic factors in breast carcinoma
    • Marrogi AJ, Munshi A, Merogi AJ, Ohadike Y, El-Habashi A, Marrogi OL. Freeman, S. M. Study of tumor infiltrating lymphocytes and transforming growth factor-beta as prognostic factors in breast carcinoma. Int J Cancer 1997; 74:492-501; http://dx.doi.org/10.1002/(SICI)1097-0215(19971021)74:5,492::AID-IJC3.3. 0.CO;2-Z
    • (1997) Int J Cancer , vol.74 , pp. 492-501
    • Marrogi, A.J.1    Munshi, A.2    Merogi, A.J.3    Ohadike, Y.4    El-Habashi, A.5    Marrogi, O.L.6    Freeman, S.M.7
  • 7
    • 0036852241 scopus 로고    scopus 로고
    • Cancer immunoediting: from immunosurveillance to tumor escape
    • Dunn GP, Bruce AT, Ikeda H, Old LJ, Schreiber RD. Cancer immunoediting: from immunosurveillance to tumor escape. Nat Immunol 2002; 3:991-8; http://dx.doi.org/10.1038/ni1102-991
    • (2002) Nat Immunol , vol.3 , pp. 991-998
    • Dunn, G.P.1    Bruce, A.T.2    Ikeda, H.3    Old, L.J.4    Schreiber, R.D.5
  • 8
    • 4143141823 scopus 로고    scopus 로고
    • The immunobiology of cancer immunosurveillance and immunoediting
    • Dunn GP, Old LJ, Schreiber RD. The immunobiology of cancer immunosurveillance and immunoediting. Immunity 2004; 21:137-48; http://dx.doi.org/10.1016/j.immuni.2004.07.017
    • (2004) Immunity , vol.21 , pp. 137-148
    • Dunn, G.P.1    Old, L.J.2    Schreiber, R.D.3
  • 9
    • 0032560475 scopus 로고    scopus 로고
    • Demonstration of an interferon gamma-dependent tumor surveillance system in immunocompetent mice
    • Kaplan DH, Shankaran V, Dighe AS, Stockert E, Aguet M, Old LJ, et al. Demonstration of an interferon gamma-dependent tumor surveillance system in immunocompetent mice. Proc Natl Acad Sci USA 1998; 95:7556-61; http://dx.doi.org/10.1073/pnas.95.13.7556
    • (1998) Proc Natl Acad Sci USA , vol.95 , pp. 7556-7561
    • Kaplan, D.H.1    Shankaran, V.2    Dighe, A.S.3    Stockert, E.4    Aguet, M.5    Old, L.J.6
  • 10
    • 3242796686 scopus 로고    scopus 로고
    • Specifically activated memory T cell subsets from cancer patients recognize and reject xenotransplanted autologous tumors
    • Beckhove P, Feuerer M, Dolenc M, Schuetz F, Choi C, Sommerfeldt N, et al. Specifically activated memory T cell subsets from cancer patients recognize and reject xenotransplanted autologous tumors. J Clin Invest 2004; 114:67-76;
    • (2004) J Clin Invest , vol.114 , pp. 67-76
    • Beckhove, P.1    Feuerer, M.2    Dolenc, M.3    Schuetz, F.4    Choi, C.5    Sommerfeldt, N.6
  • 12
    • 33748987908 scopus 로고    scopus 로고
    • Cancer despite immunosurveillance: immunoselection and immunosubversion
    • Zitvogel L, Tesniere A, Kroemer G. Cancer despite immunosurveillance: immunoselection and immunosubversion. Nat Rev Immunol 2006; 6:715-27; http://dx.doi.org/10.1038/nri1936
    • (2006) Nat Rev Immunol , vol.6 , pp. 715-727
    • Zitvogel, L.1    Tesniere, A.2    Kroemer, G.3
  • 13
    • 30144444279 scopus 로고    scopus 로고
    • Enhancement of vaccine-mediated antitumor immunity in cancer patients after depletion of regulatory T cells
    • Dannull J, Su Z, Rizzieri D, Yang BK, Coleman D, Yancey D, et al. Enhancement of vaccine-mediated antitumor immunity in cancer patients after depletion of regulatory T cells. J Clin Invest 2005; 115:3623-33; http://dx.doi.org/10.1172/JCI25947
    • (2005) J Clin Invest , vol.115 , pp. 3623-3633
    • Dannull, J.1    Su, Z.2    Rizzieri, D.3    Yang, B.K.4    Coleman, D.5    Yancey, D.6
  • 14
    • 27644457376 scopus 로고    scopus 로고
    • TGF-beta directly targets cytotoxic T cell functions during tumor evasion of immune surveillance
    • Thomas DA, Massague J. TGF-beta directly targets cytotoxic T cell functions during tumor evasion of immune surveillance. Cancer Cell 2005; 8:369-80; http://dx.doi.org/10.1016/j.ccr.2005.10.012
    • (2005) Cancer Cell , vol.8 , pp. 369-380
    • Thomas, D.A.1    Massague, J.2
  • 15
    • 34547655923 scopus 로고    scopus 로고
    • A unique subset of CD4 +CD25highFoxp3+ T cells secreting interleukin-10 and transforming growth factor-beta1 mediates suppression in the tumor microenvironment
    • Strauss L, Bergmann C, Szczepanski M, Gooding W, Johnson JT, Whiteside TL. A unique subset of CD4 +CD25highFoxp3+ T cells secreting interleukin-10 and transforming growth factor-beta1 mediates suppression in the tumor microenvironment. Clin Cancer Res 2007; 13:4345-54; http://dx.doi.org/10.1158/1078-0432.CCR-07-0472
    • (2007) Clin Cancer Res , vol.13 , pp. 4345-4354
    • Strauss, L.1    Bergmann, C.2    Szczepanski, M.3    Gooding, W.4    Johnson, J.T.5    Whiteside, T.L.6
  • 16
    • 0035953308 scopus 로고    scopus 로고
    • IFNgamma and lymphocytes prevent primary tumour development and shape tumour immunogenicity
    • Shankaran V, Ikeda H, Bruce AT, White JM, Swanson PE, Old LJ, et al. IFNgamma and lymphocytes prevent primary tumour development and shape tumour immunogenicity. Nature 2001; 410:1107-11; http://dx.doi.org/10.1038/35074122
    • (2001) Nature , vol.410 , pp. 1107-1111
    • Shankaran, V.1    Ikeda, H.2    Bruce, A.T.3    White, J.M.4    Swanson, P.E.5    Old, L.J.6
  • 17
    • 0012929728 scopus 로고    scopus 로고
    • Toll-like receptors
    • Takeda K, Kaisho T, Akira S. Toll-like receptors. Annu Rev Immunol 2003; 21:335-76; http://dx.doi.org/10.1146/annurev.immunol.21.120601.141126
    • (2003) Annu Rev Immunol , vol.21 , pp. 335-376
    • Takeda, K.1    Kaisho, T.2    Akira, S.3
  • 18
  • 19
    • 25144522269 scopus 로고    scopus 로고
    • Recurrence rate of superficial basal cell carcinoma following successful treatment with imiquimod 5% cream: interim 2-year results from an ongoing 5-year follow-up study in Europe
    • Gollnick H, Barona CG, Frank RG, Ruzicka T, Megahed M, Tebbs V, et al. Recurrence rate of superficial basal cell carcinoma following successful treatment with imiquimod 5% cream: interim 2-year results from an ongoing 5-year follow-up study in Europe. Eur J Dermatol 2005; 15:374-81;
    • (2005) Eur J Dermatol , vol.15 , pp. 374-381
    • Gollnick, H.1    Barona, C.G.2    Frank, R.G.3    Ruzicka, T.4    Megahed, M.5    Tebbs, V.6
  • 20
    • 79956359126 scopus 로고    scopus 로고
    • Imiquimod can be combined with cryosurgery (immunocryosurgery) for locally advanced perocular basal cell carcinomas
    • Gaitanis G, Kalogeropoulos C, Bassukas ID. Imiquimod can be combined with cryosurgery (immunocryosurgery) for locally advanced perocular basal cell carcinomas. Br J Ophthalmol 2011; 95:890-2; http://dx.doi.org/10.1136/bjo.2010.195800
    • (2011) Br J Ophthalmol , vol.95 , pp. 890-892
    • Gaitanis, G.1    Kalogeropoulos, C.2    Bassukas, I.D.3
  • 21
    • 67649884707 scopus 로고    scopus 로고
    • Beyond a decade of 5% imiquimod topical therapy
    • Gaspari A, Tyring SK, Rosen T. Beyond a decade of 5% imiquimod topical therapy. J Drugs Dermatol 2009; 8:467-74;
    • (2009) J Drugs Dermatol , vol.8 , pp. 467-474
    • Gaspari, A.1    Tyring, S.K.2    Rosen, T.3
  • 22
    • 0033775777 scopus 로고    scopus 로고
    • Adjuvant activities of immune response modifier R-848: comparison with CpG ODN
    • Vasilakos JP, Smith RM, Gibson SJ, Lindh JM, Pederson LK, Reiter MJ, et al. Adjuvant activities of immune response modifier R-848: comparison with CpG ODN. Cell Immunol 2000; 204:64-74; http://dx.doi.org/10.1006/cimm.2000.1689
    • (2000) Cell Immunol , vol.204 , pp. 64-74
    • Vasilakos, J.P.1    Smith, R.M.2    Gibson, S.J.3    Lindh, J.M.4    Pederson, L.K.5    Reiter, M.J.6
  • 23
    • 26644447379 scopus 로고    scopus 로고
    • TLR agonists as vaccine adjuvants: comparison of CpG ODN and Resiquimod (R-848)
    • Risini D, Weeratna RD, Shawn R. Makinen, McCluskie MJ, Davis HL. TLR agonists as vaccine adjuvants: comparison of CpG ODN and Resiquimod (R-848). Vaccine 2005; 23:5263-70; http://dx.doi.org/10.1016/j.vaccine.2005.06.024
    • (2005) Vaccine , vol.23 , pp. 5263-5270
    • Risini, D.1    Weeratna, R.D.2    Makinen, S.R.3    McCluskie, M.J.4    Davis, H.L.5
  • 24
    • 33847342938 scopus 로고    scopus 로고
    • Immunostimulatory RNA is a potent inducer of antigen-specific cytotoxic and humoral immune response in vivo
    • Hamm S, Heit A, Koffler M, Huster KM, Akira S, Busch DH, et al. Immunostimulatory RNA is a potent inducer of antigen-specific cytotoxic and humoral immune response in vivo. Int Immunol 2007; 19:297-304; http://dx.doi.org/10.1093/intimm/dxl146
    • (2007) Int Immunol , vol.19 , pp. 297-304
    • Hamm, S.1    Heit, A.2    Koffler, M.3    Huster, K.M.4    Akira, S.5    Busch, D.H.6
  • 25
    • 79953065996 scopus 로고    scopus 로고
    • Topical imiquimod has therapeutic and immunomodulatory effects against intracranial tumors
    • Xiong Z, Ohlfest JR. Topical imiquimod has therapeutic and immunomodulatory effects against intracranial tumors. J Immunother 2011; 34:264-9; http://dx.doi.org/10.1097/CJI.0b013e318209eed4
    • (2011) J Immunother , vol.34 , pp. 264-269
    • Xiong, Z.1    Ohlfest, J.R.2
  • 26
    • 0036088492 scopus 로고    scopus 로고
    • Human TLR7 or TLR8 independently confer responsiveness to the antiviral compound R-848
    • Jurk M, Heil F, Vollmer J, Schetter C, Krieg AM, Wagner H, et al. Human TLR7 or TLR8 independently confer responsiveness to the antiviral compound R-848. Nat Immunol 2002; 3:499; http://dx.doi.org/10.1038/ni0602-499
    • (2002) Nat Immunol , vol.3 , pp. 499
    • Jurk, M.1    Heil, F.2    Vollmer, J.3    Schetter, C.4    Krieg, A.M.5    Wagner, H.6
  • 27
    • 35449004503 scopus 로고    scopus 로고
    • Intracranial glioblastoma models in preclinical neuro-oncology: neuropathological characterization and tumor progression
    • Candolfi M, Curtin JF, Nichols WS, Muhammad AG, King GD, Pluhar GE, et al. Intracranial glioblastoma models in preclinical neuro-oncology: neuropathological characterization and tumor progression. J Neurooncol 2007; 85:133-48; http://dx.doi.org/10.1007/s11060-007-9400-9
    • (2007) J Neurooncol , vol.85 , pp. 133-148
    • Candolfi, M.1    Curtin, J.F.2    Nichols, W.S.3    Muhammad, A.G.4    King, G.D.5    Pluhar, G.E.6
  • 28
    • 0023182961 scopus 로고
    • Effect of low dose cyclophosphamide on the immune system of cancer patients: reduction of T-suppressor function without depletion of the CD8+ subset
    • Berd D, Mastrangelo MJ. Effect of low dose cyclophosphamide on the immune system of cancer patients: reduction of T-suppressor function without depletion of the CD8+ subset. Cancer Res 1987; 47:3317-21;
    • (1987) Cancer Res , vol.47 , pp. 3317-3321
    • Berd, D.1    Mastrangelo, M.J.2
  • 30
    • 0021741471 scopus 로고
    • Effects of chemotherapeutic agents on the immune response
    • Kempf RA, Mitchell MS. Effects of chemotherapeutic agents on the immune response. Cancer Invest 1984; 2:459-66; http://dx.doi.org/10.3109/07357908409048519
    • (1984) Cancer Invest , vol.2 , pp. 459-466
    • Kempf, R.A.1    Mitchell, M.S.2
  • 31
    • 0028630920 scopus 로고
    • A rat glioblastoma model, CNS-1, with invasive characteristics similar to those of human gliomas: a comparison to 9L gliosarcoma
    • Kruse CA, Molleston MC, Parks EP, Schiltz PM, Kleinschmidt-DeMasters BK, Hickey WF. A rat glioblastoma model, CNS-1, with invasive characteristics similar to those of human gliomas: a comparison to 9L gliosarcoma. J Neurooncol 1994; 22:191-200; http://dx.doi.org/10.1007/BF01052919
    • (1994) J Neurooncol , vol.22 , pp. 191-200
    • Kruse, C.A.1    Molleston, M.C.2    Parks, E.P.3    Schiltz, P.M.4    Kleinschmidt-DeMasters, B.K.5    Hickey, W.F.6
  • 32
    • 79955640835 scopus 로고    scopus 로고
    • Mechanisms of immunomodulation in human glioblastoma
    • Avril T, Vauleon E, Tanguy-Royer S, Mosser J, Quillien V. Mechanisms of immunomodulation in human glioblastoma. Immunotherapy 2011; 3(Suppl): 42-4; http://dx.doi.org/10.2217/imt.11.39
    • (2011) Immunotherapy; , vol.3 , Issue.SUPPL. , pp. 42-44
    • Avril, T.1    Vauleon, E.2    Tanguy-Royer, S.3    Mosser, J.4    Quillien, V.5
  • 33
    • 33748749338 scopus 로고    scopus 로고
    • Immune resistence orchestrated by the tumor microenvirenment
    • Gajewski TF, Meng Y, Blank C, Brown I, Kacha A, Kline J, et al. Immune resistence orchestrated by the tumor microenvirenment. Immunol Rev 2006; 213: 131-45; http://dx.doi.org/10.1111/j.1600-065X.2006.00442.x
    • (2006) Immunol Rev , vol.213 , pp. 131-145
    • Gajewski, T.F.1    Meng, Y.2    Blank, C.3    Brown, I.4    Kacha, A.5    Kline, J.6
  • 34
    • 0025745414 scopus 로고
    • Modulation of T-cell function by gliomas
    • Roszman T, Elliott L, Brooks W. Modulation of T-cell function by gliomas. Immunol Today 1991; 12:370-4; http://dx.doi.org/10.1016/0167-5699(91)90068-5
    • (1991) Immunol Today , vol.12 , pp. 370-374
    • Roszman, T.1    Elliott, L.2    Brooks, W.3
  • 35
    • 79955080612 scopus 로고    scopus 로고
    • Immunotherapy of brain cancers: the past, the present and future directions
    • Epub
    • Ge L, Hoa N, Bota DA, Natividad J, Howat A, Jadus MR. Immunotherapy of brain cancers: the past, the present and future directions. Clin Dev Immunol 2010; 296453; Epub; http://dx.doi.org/10.1155/2010/296453
    • (2010) Clin Dev Immunol , pp. 296453
    • Ge, L.1    Hoa, N.2    Bota, D.A.3    Natividad, J.4    Howat, A.5    Jadus, M.R.6
  • 36
    • 77951196379 scopus 로고    scopus 로고
    • Triggering of TLR7 and TLR8 expressed by human lung cancer cells induces cell survival and chemoresistance
    • Cherfils-Vicini J, Platonova S, Gillard M, Laurans L, Validire P, Caliandro R, et al. Triggering of TLR7 and TLR8 expressed by human lung cancer cells induces cell survival and chemoresistance. J Clin Invest 2010; 120:1285-97; http://dx.doi.org/10.1172/JCI36551
    • (2010) J Clin Invest , vol.120 , pp. 1285-1297
    • Cherfils-Vicini, J.1    Platonova, S.2    Gillard, M.3    Laurans, L.4    Validire, P.5    Caliandro, R.6
  • 37
    • 0027230753 scopus 로고
    • Systemic Chemotherapy Combined with Local Adoptive Immunotherapy Cures Rats Bearing 9L Gliosarcoma
    • Kruse CA, Mitchell DH, Kleinschmidt-DeMasters BK, Bellgrau D, Eule JM, Parra JR, et al. Systemic Chemotherapy Combined with Local Adoptive Immunotherapy Cures Rats Bearing 9L Gliosarcoma. J Neurooncol 1993; 15:97-112; http://dx.doi.org/10.1007/BF01053931
    • (1993) J Neurooncol , vol.15 , pp. 97-112
    • Kruse, C.A.1    Mitchell, D.H.2    Kleinschmidt-DeMasters, B.K.3    Bellgrau, D.4    Eule, J.M.5    Parra, J.R.6
  • 38
    • 0035734114 scopus 로고    scopus 로고
    • Chemoimmunotherapy and chemo- adoptive immunotherapy of cancer
    • Gomez GG, Hutchison R, Kruse CA. Chemoimmunotherapy and chemo- adoptive immunotherapy of cancer. Cancer Treat Rev 2001; 27:375-402;
    • (2001) Cancer Treat Rev , vol.27 , pp. 375-402
    • Gomez, G.G.1    Hutchison, R.2    Kruse, C.A.3
  • 39
    • 34250324345 scopus 로고    scopus 로고
    • Tumoricidal activity of TLR7/8-activated inflammatory dendritic cells
    • Stary G, Bangert C, Tauber M, Strohal R, Kopp T, Sting G. Tumoricidal activity of TLR7/8-activated inflammatory dendritic cells. J Exp Med 2007; 204:1441-51; http://dx.doi.org/10.1084/jem.20070021
    • (2007) J Exp Med , vol.204 , pp. 1441-1451
    • Stary, G.1    Bangert, C.2    Tauber, M.3    Strohal, R.4    Kopp, T.5    Sting, G.6
  • 40
    • 0033790111 scopus 로고    scopus 로고
    • Effect of food on the pharmacokinetics and bioavailability of oral imiquimod relative to a subcutaneous dose
    • Soria I, Myhre P, Horton V, Ellefson P, McCarville S, Schmitt K, et al. Effect of food on the pharmacokinetics and bioavailability of oral imiquimod relative to a subcutaneous dose. Int J Clin Pharmacol Ther 2000; 38:476-81;
    • (2000) Int J Clin Pharmacol Ther , vol.38 , pp. 476-481
    • Soria, I.1    Myhre, P.2    Horton, V.3    Ellefson, P.4    McCarville, S.5    Schmitt, K.6
  • 41
    • 0001891726 scopus 로고    scopus 로고
    • High specificity and robustness of AccuPrimeTM Taq provides the ideal tool for demanding miniaturized, multiplex, and high-throughput PCR
    • Westfall B, Sitaraman K, Solus J, Hughes J, Rashtchian A. High specificity and robustness of AccuPrimeTM Taq provides the ideal tool for demanding miniaturized, multiplex, and high-throughput PCR. Focus 1997; 19:46.
    • (1997) Focus , vol.19 , pp. 46
    • Westfall, B.1    Sitaraman, K.2    Solus, J.3    Hughes, J.4    Rashtchian, A.5
  • 42
    • 79953065996 scopus 로고    scopus 로고
    • Topical Imiquimod has therapeutic and immunomodulaotory effects against intracranialt tumors
    • Xiong Z, Ohlfest J. Topical Imiquimod has therapeutic and immunomodulaotory effects against intracranialt tumors. J Immunother 2011; 34:264-9; http://dx.doi.org/10.1097/CJI.0b013e318209eed4
    • (2011) J Immunother , vol.34 , pp. 264-269
    • Xiong, Z.1    Ohlfest, J.2


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