Why size matters: Differences in brain volume account for apparent sex differences in callosal anatomy. The sexual dimorphism of the corpus callosum

NeuroImage

Volumn 84, Issue , 2014, Pages 820-824

  Luders, Eileen ^a   Toga, Arthur W ^a   Thompson, Paul M ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

Brain; Corpus callosum; Gender; MRI; Sex

Indexed keywords

ADULT; ARTICLE; BRAIN SIZE; COMPARATIVE STUDY; CONTROLLED STUDY; CORPUS CALLOSUM; FEMALE; HUMAN; MALE; NEUROANATOMY; NEUROIMAGING; NUCLEAR MAGNETIC RESONANCE SCANNER; PRIORITY JOURNAL; SEX DIFFERENCE; VALIDATION STUDY; WHITE MATTER;

BRAIN; CORPUS CALLOSUM; GENDER; MRI; SEX;

ADULT; AGED; CORPUS CALLOSUM; FEMALE; HUMANS; IMAGE PROCESSING, COMPUTER-ASSISTED; MAGNETIC RESONANCE IMAGING; MALE; MIDDLE AGED; ORGAN SIZE; SEX CHARACTERISTICS; YOUNG ADULT;

EID: 84885816857     PISSN: 10538119     EISSN: 10959572     Source Type: Journal    
DOI: 10.1016/j.neuroimage.2013.09.040     Document Type: Article

References (36)

1. Barnes J., Ridgway G.R., Bartlett J., Henley S.M., Lehmann M., Hobbs N., Clarkson M.J., MacManus D.G., Ourselin S., Fox N.C. Head size, age and gender adjustment in MRI studies: a necessary nuisance?. NeuroImage 2010, 53:1244-1255.
2. Benjamini Y., Hochberg Y. Controlling the false discovery rate: a practical and powerful approach to multiple testing. J. R. Stat. Soc. 1995, 57:289-300.
3. Bermudez P., Zatorre R.J. Sexual dimorphism in the corpus callosum: methodological considerations in MRI morphometry. NeuroImage 2001, 13:1121-1130.
4. Bishop K.M., Wahlsten D. Sex differences in the human corpus callosum: myth or reality?. Neurosci. Biobehav. Rev. 1997, 21:581-601.
5. Bruner E., de la Cuetara J.M., Colom R., Martin-Loeches M. Gender-based differences in the shape of the human corpus callosum are associated with allometric variations. J. Anat. 2012, 220:417-421.
6. DeLacoste-Utamsing C., Holloway R.L. Sexual dimorphism in the human corpus callosum. Science 1982, 216:1431-1432.
7. Driesen N.R., Raz N. The influence of sex, age, and handedness on corpus callosum morphology: a meta-analysis. Psychobiology 1995, 23:240-247.
8. Giedd J.N., Blumenthal J., Jeffries N.O., Rajapakse J.C., Vaituzis A.C., Liu H., Berry Y.C., Tobin M., Nelson J., Castellanos F.X. Development of the human corpus callosum during childhood and adolescence: a longitudinal MRI study. Prog. Neuropsychopharmacol. Biol. Psychiatry 1999, 23:571-588.
9. Hwang S.J., Ji E.K., Lee E.K., Kim Y.M., Shin d.Y., Cheon Y.H., Rhyu I.J. Gender differences in the corpus callosum of neonates. Neuroreport 2004, 15:1029-1032.
10. Jancke L., Staiger J.F., Schlaug G., Huang Y., Steinmetz H. The relationship between corpus callosum size and forebrain volume. Cereb. Cortex 1997, 7:48-56.
11. Jancke L., Preis S., Steinmetz H. The relation between forebrain volume and midsagittal size of the corpus callosum in children. Neuroreport 1999, 10:2981-2985.
12. Lee D.J., Chen Y., Schlaug G. Corpus callosum: musician and gender effects. Neuroreport 2003, 14:205-209.
13. Leonard C.M., Towler S., Welcome S., Halderman L.K., Otto R., Eckert M.A., Chiarello C. Size matters: cerebral volume influences sex differences in neuroanatomy. Cereb. Cortex 2008, 18:2920-2931.
14. Liu F., Vidarsson L., Winter J.D., Tran H., Kassner A. Sex differences in the human corpus callosum microstructure: a combined T2 myelin-water and diffusion tensor magnetic resonance imaging study. Brain Res. 2010, 1343:37-45.
15. Luders E., Steinmetz H., Jancke L. Brain size and grey matter volume in the healthy human brain. Neuroreport 2002, 13:2371-2374.
16. Luders E., Rex D.E., Narr K.L., Woods R.P., Jancke L., Thompson P.M., Mazziotta J.C., Toga A.W. Relationships between sulcal asymmetries and corpus callosum size: gender and handedness effects. Cereb. Cortex 2003, 13:1084-1093.
17. Luders E., Narr K.L., Zaidel E., Thompson P.M., Jancke L., Toga A.W. Parasagittal asymmetries of the corpus callosum. Cereb. Cortex 2006, 16:346-354.
18. Luders E., Narr K.L., Zaidel E., Thompson P.M., Toga A.W. Gender effects on callosal thickness in scaled and unscaled space. Neuroreport 2006, 17:1103-1106.
19. Luders E., Di Paola M., Tomaiuolo F., Thompson P.M., Toga A.W., Vicari S., Petrides M., Caltagirone C. Callosal morphology in Williams syndrome: a new evaluation of shape and thickness. Neuroreport 2007, 18:203-207.
20. Luders E., Gaser C., Narr K.L., Toga A.W. Why sex matters: brain size independent differences in gray matter distributions between men and women. J. Neurosci. 2009, 29:14265-14270.
21. Luders E., Thompson P.M., Toga A.W. The development of the corpus callosum in the healthy human brain. J. Neurosci. 2010, 30:10985-10990.
22. Mazziotta J.C., Woods R., Iacoboni M., Sicotte N., Yaden K., Tran M., Bean C., Kaplan J., Toga A.W. The myth of the normal, average human brain-the ICBM experience: (1) subject screening and eligibility. NeuroImage 2009, 44:914-922.
23. Ng W.H., Chan Y.L., Au K.S., Yeung K.W., Kwan T.F., To C.Y. Morphometry of the corpus callosum in Chinese children: relationship with gender and academic performance. Pediatr. Radiol. 2005, 35:565-571.
24. Ringo J.L., Doty R.W., Demeter S., Simard P.Y. Time is of the essence: a conjecture that hemispheric specialization arises from interhemispheric conduction delay. Cereb. Cortex 1994, 4:331-343.
25. Shattuck D.W., Sandor-Leahy S.R., Schaper K.A., Rottenberg D.A., Leahy R.M. Magnetic resonance image tissue classification using a partial volume model. NeuroImage 2001, 13:856-876.
26. Smith R.J. Relative size versus controlling for size. Interpretation of ratios on sexual dimorphism in the human corpus callosum. Curr. Anthropol. 2005, 46:249-273.
27. Sowell E.R., Peterson B.S., Kan E., Woods R.P., Yoshii J., Bansal R., Xu D., Zhu H., Thompson P.M., Toga A.W. Sex differences in cortical thickness mapped in 176 healthy individuals between 7 and 87years of age. Cereb. Cortex 2007, 17:1550-1560.
28. Steinmetz H., Staiger J.F., Schlaug S.G., Huang Y., Jancke L. Inverse relationship between brain size and callosal connectivity. Naturwissenschaften 1996, 83:221.
29. Sullivan E.V., Rosenbloom M.J., Desmond J.E., Pfefferbaum A. Sex differences in corpus callosum size: relationship to age and intracranial size. Neurobiol. Aging 2001, 22:603-611.
30. Thompson P.M., Schwartz C., Lin R.T., Khan A.A., Toga A.W. Three-dimensional statistical analysis of sulcal variability in the human brain. J. Neurosci. 1996, 16:4261-4274.
31. Thompson P.M., Schwartz C., Toga A.W. High-resolution random mesh algorithms for creating a probabilistic 3D surface atlas of the human brain. NeuroImage 1996, 3:19-34.
32. Westerhausen R., Walter C., Kreuder F., Wittling R.A., Schweiger E., Wittling W. The influence of handedness and gender on the microstructure of the human corpus callosum: a diffusion-tensor magnetic resonance imaging study. Neurosci. Lett. 2003, 351:99-102.
33. Westerhausen R., Kreuder F., Dos Santos S.S., Walter C., Woerner W., Wittling R.A., Schweiger E., Wittling W. Effects of handedness and gender on macro- and microstructure of the corpus callosum and its subregions: a combined high-resolution and diffusion-tensor MRI study. Brain Res. Cogn. Brain Res. 2004, 21:418-426.
34. Westerhausen R., Kompus K., Dramsdahl M., Falkenberg L.E., Gruner R., Hjelmervik H., Specht K., Plessen K., Hugdahl K. A critical re-examination of sexual dimorphism in the corpus callosum microstructure. NeuroImage 2011, 56:874-880.
35. Witelson S.F. Hand and sex differences in the isthmus and genu of the human corpus callosum. A postmortem morphological study. Brain 1989, 112(Pt 3):799-835.
36. Woods R.P., Grafton S.T., Holmes C.J., Cherry S.R., Mazziotta J.C. Automated image registration: I. General methods and intrasubject, intramodality validation. J. Comput. Assist. Tomogr. 1998, 22:139-152.