Baker's yeast β-glucan SUPPL.ementation increases monocytes and cytokines post-exercise: Implications for infection risk?

British Journal of Nutrition

Volumn 109, Issue 3, 2013, Pages 478-486

  Carpenter, K C ^a   Breslin, W L ^a   Davidson, T ^a   Adams, A ^a   McFarlin, B K ^a  

^a UNIVERSITY OF HOUSTON   (United States)

Author keywords

Glucan SUPPL.ementation; Immunity; Infection susceptibility; Wellmune

Indexed keywords

BETA 1,3 GLUCAN; BETA 1,6 GLUCAN; BETA GLUCAN; CD14 ANTIGEN; CD16 ANTIGEN; FUNGAL POLYSACCHARIDE; GAMMA INTERFERON; INTERLEUKIN 2; INTERLEUKIN 4; INTERLEUKIN 5; LIPOPOLYSACCHARIDE;

ADULT; ARTICLE; BLOOD SAMPLING; CONTROLLED STUDY; CROSSOVER PROCEDURE; CYTOKINE PRODUCTION; DIET SUPPLEMENTATION; DOUBLE BLIND PROCEDURE; ENVIRONMENTAL TEMPERATURE; EXERCISE; FEMALE; FLOUR; FLOW CYTOMETRY; HEAT; HUMAN; HUMAN EXPERIMENT; HUMIDITY; IMMUNOREGULATION; IMMUNOSTIMULATION; INFECTION RISK; INNATE IMMUNITY; MALE; MONOCYTE; NORMAL HUMAN; RECREATION; RICE; SACCHAROMYCES CEREVISIAE;

ADOLESCENT; ADULT; BETA-GLUCANS; BICYCLING; CELLS, CULTURED; CROSS-OVER STUDIES; CYTOKINES; DIETARY SUPPLEMENTS; DOUBLE-BLIND METHOD; EXERCISE; FEMALE; HUMANS; IMMUNITY, INNATE; IMMUNOMODULATION; LEUKOCYTE COUNT; MALE; MONOCYTES; SACCHAROMYCES CEREVISIAE; STRESS, PHYSIOLOGICAL; TEXAS; YOUNG ADULT;

EID: 84885771707     PISSN: 00071145     EISSN: 14752662     Source Type: Journal    
DOI: 10.1017/S0007114512001407     Document Type: Article

References (35)

1. Woods JA, Davis JM, Smith JA, et al. (1999) Exercise and cellular innate immune function. Med Sci Sports Exerc 31, 57-66. (Pubitemid 29036360)
2. McFarlin BK, Flynn MG, Stewart LK, et al. (2004) Carbohydrate intake during endurance exercise increases natural killer cell responsiveness to IL-2. J Appl Physiol 96, 271-275. (Pubitemid 38032010)
3. Walsh NP & Whitham M (2006) Exercising in environmental extremes: A greater threat to immune function? Sports Med 36, 941-976. (Pubitemid 44736912)
4. Pedersen BK & Ullum H (1994) NK cell response to phys ical activity: Possible mechanisms of action. Med Sci Sports Exerc 26, 140-146. (Pubitemid 24054774)
5. Gleeson M, McFarlin B & Flynn M (2006) Exercise and Tolllike receptors. Exerc Immun Rev 12, 34-53.
6. McFarlin BK, Hutchison AT & Kueht ML (2008) Knowledge of carbohydrate consumption does not alter natural killer cell activity following an acute bout of high-intensity aerobic exercise. Appl Physiol N utr Metab 33, 1007-1012.
7. Steensberg A, Toft AD, Bruunsgaard H, et al. (2001) Strenuous exercise decreases the percentage of type 1 T cells in the circulation. J Appl Physiol 91, 1708-1712. (Pubitemid 32900363)
8. McFarlin BK, Flynn MG & Hampton T (2007) Carbohydrate consumption during cycling increases in vitro NK cell responses to IL-2 and IFN-gamma. Brain Behav Immun 21, 202-208. (Pubitemid 46038911)
9. McFarlin BK, Flynn MG, Phillips MD, et al. (2005) Chronic resistance exercise training improves natural killer cell activity in older women. J Gerontol A Biol Sci Med Sci 60, 1315-1318. (Pubitemid 41612427)
10. Allendorf DJ, Yan J, Ross GD, et al. (2005) C5a-mediated leukotriene B4-amplified neutrophil chemotaxis is essential in tumor immunotherapy facilitated by anti-tumor monoclonal antibody and beta-glucan. J Immunol 174, 7050-7056. (Pubitemid 40705670)
11. Driscoll M, Hansen R, Ding C, et al. (2009) Therapeutic potential of various beta-glucan sources in conjunction with anti-tumor monoclonal antibody in cancer therapy. Cancer Biol Ther 8, 218-225.
12. Lavigne LM, Albina JE & Reichner JS (2006) Beta-glucan is a fungal determinant for adhesion-dependent human neutrophil functions. J Immunol 177, 8667-8675. (Pubitemid 44893831)
13. Li B, Allendorf DJ, Hansen R, et al. (2007) Combined yeast {beta} -glucan and antitumor monoclonal antibody therapy requires C5a-mediated neutrophil chemotaxis via regulation of decay-accelerating factor CD55. Cancer Res 67, 7421-7430. (Pubitemid 47206572)
14. Wakshull E, Brunke-Reese D, Lindermuth J, et al. (1999) PGG-glucan, a soluble beta-(1,3)-glucan, enhances the oxidative burst response, microbicidal activity, and activates an NF-kappa B-like factor in human PMN: Evidence for a glycosphingolipid beta-(1,3)-glucan receptor. Immunopharmacology 41, 89-107. (Pubitemid 29099822)
15. us Pharmacopiea (2011) Beta glucan from bakers yeast (Saccharomyces cerevisiae). In Food Chemicals Codex, 7th ed, 3rd SUPPL.ement [us Pharmacopiea, editor]. New York: US Pharmacopiea.
16. Talbott ST & Talbott J (2009) Effect of beta 1,3/1,6 glucan on upper respiratory tract infection symptoms and mood state in marathon athletes. J Sports Sci Med 8, 509-515.
17. Harger-Domitrovich SG, Domitrovich JW & Ruby BC (2008) Effects of an immunomodulating SUPPL.ement on upper respiratory tract infection symptoms in wildland firefi ghters. Med Sci Sports Exerc 40, S353.
18. McFarlin BK, Mitchell JB, McFarlin MA, et al. (2003) Repeated endurance exercise affects leukocyte number but not NK cell activity. Med Sci Sports Exerc 35, 1130-1138. (Pubitemid 36807974)
19. McFarlin BK & Mitchell JB (2003) Exercise in hot and cold environments: Differential effects on leukocyte number and NK cell activity. Aviat Space Environ Med 74, 1231-1236. (Pubitemid 37523127)
20. Ehrman JK (2010) American College of Sports Medicine. ACSM? s Resource Manual for Guidelines for Exercise Testing and Prescription, 6th ed. Philadelphia, PA: Wolters Kluwer Health/Lippincott Williams & Wilkins.
21. McFarlin BK, Flynn MG, Campbell WW, et al. (2004) TLR4 is lower in resistance-trained older women and related to inflammatory cytokines. Med Sci Sports Exerc 36, 1876-1883. (Pubitemid 39473505)
22. McFarlin BK, Flynn MG, Campbell WW, et al. (2006) Physical activity status, but not age, influences inflammatory biomarkers and toll-like receptor J Gerontol A Biol Sci Med Sci 61, 388-393.
23. Bergendiova K, Tibenska E & Majtan J (2011) Pleuran (betaglucan from Pleurotus ostreatus) SUPPL.ementation, cellular immune response and respiratory tract infections in athletes. Eur J Appl Physiol 111, 2033-2040.
24. Murphy EA, Davis JM, Carmichael MD, et al. (2009) Benefits of oat beta-glucan and sucrose feedings on infection and macrophage antiviral resistance following exercise stress. A m J Physiol Regul Integr Comp Physiol 297, R1188-R1194.
25. Nieman DC, Henson DA, McMahon M, et al. (2008) Beta-glucan, immune function, and upper respiratory tract infections in athletes. Med Sc i Sports Exerc 40, 1463-1471.
26. Murphy EA, Davis JM, Brown AS, et al. (2008) Benefits of oat beta-glucan on respiratory infection following exercise stress: Role of lung macrophages. Am J Physi ol Regul Integr Compar Physiol 294, R1593-R1599.
27. Simpson RJ, McFarlin BK, McSporran C, et al. (2009) Toll-like receptor expression on classic and pro-inflammatory blood monocytes after acute exercise in humans. Brain Behav Immun 23, 232-239.
28. Flynn MG, McFarlin BK, Phillips MD, et al. (2003) Toll-like receptor 4 and CD14 mRNA expression are lower in resistive exercise-trained elderly w omen. J Appl Physiol 95, 1833-1842. (Pubitemid 37310365)
29. Walsh NP, Gleeson M, Shephard RJ, et al. (2011) Position statement. Part one: Immune function and exercise. Exerc Immunol Rev 17, 6-63.
30. Ibfelt T, Petersen EW, Bruunsgaard H, et al. (2002) Exerciseinduced change in type 1 cytokine-producing CD8 ? T cells is related to a decrease in memory T cells. J Appl Physiol 93, 645-648. (Pubitemid 34810229)
31. Iijima N, Mattei LM & Iwasaki A (2011) Recruited inflammatory monocytes stimulate antiviral Th1 immunity in infected tissue. Proc Natl Acad Sci U S A 108, 284-289.
32. Lancaster GI, Halson SL, Khan Q, et al. (2004) Effects of acute exhaustive exercise and chronic exercise training on type 1 and type 2 T lymphocytes. Exerc Immunol Rev 10, 91-106.
33. Hong F, Yan J, Baran JT, et al. (2004) Mechanism by which orally administered beta-1,3-glucans enhance the tumoricidal activity of antitumor monoclonal antibodies in murine tumor models. J Immunol 173, 797-806. (Pubitemid 38924254)
34. Tsikitis VL, Morin NA, Harrington EO, et al. (2004) The lectin-like domain of complement receptor 3 protects endothelial barrier function from activated neutrophils. J Immunol 173, 1284-1291. (Pubitemid 38924307)
35. Wang PL, O ido-Mori M, Fujii T, et al. (2001) Heterogeneous expression of Toll-like receptor 4 and downregulation of Toll-like receptor 4 expression on human gingival fibroblasts by Porphyromonas gingivalis lipopolysaccharide. Biochem Biophys R es Commun 288, 863-867. (Pubitemid 33140962)