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Volumn 250, Issue , 2013, Pages 20-30

Neurovascular abnormalities in humans and mice with Huntington's disease

Author keywords

Cerebral blood volume; Huntington's disease; Microscopic magnetic resonance angiography; Microvasculature; Vessel density

Indexed keywords

COLLAGEN TYPE 4; GADOLINIUM PENTETATE MEGLUMINE;

EID: 84885746892     PISSN: 00144886     EISSN: 10902430     Source Type: Journal    
DOI: 10.1016/j.expneurol.2013.08.019     Document Type: Article
Times cited : (74)

References (51)
  • 3
    • 2642666489 scopus 로고    scopus 로고
    • Cognitive deficits in Huntington's disease are predicted by dopaminergic PET markers and brain volumes
    • Backman L., Robins-Wahlin T.B., Lundin A., Ginovart N., Farde L. Cognitive deficits in Huntington's disease are predicted by dopaminergic PET markers and brain volumes. Brain 1997, 120(Pt 12):2207-2217.
    • (1997) Brain , vol.120 , Issue.PART 12 , pp. 2207-2217
    • Backman, L.1    Robins-Wahlin, T.B.2    Lundin, A.3    Ginovart, N.4    Farde, L.5
  • 4
    • 64449086483 scopus 로고    scopus 로고
    • Angiogenesis after cerebral ischemia
    • Beck H., Plate K.H. Angiogenesis after cerebral ischemia. Acta Neuropathol. 2009, 117(5):481-496.
    • (2009) Acta Neuropathol. , vol.117 , Issue.5 , pp. 481-496
    • Beck, H.1    Plate, K.H.2
  • 5
    • 80052330506 scopus 로고    scopus 로고
    • Amyloid triggers extensive cerebral angiogenesis causing blood brain barrier permeability and hypervascularity in Alzheimer's disease
    • Biron K.E., Dickstein D.L., Gopaul R., Jefferies W.A. Amyloid triggers extensive cerebral angiogenesis causing blood brain barrier permeability and hypervascularity in Alzheimer's disease. PLoS One 2011, 6(8):e23789.
    • (2011) PLoS One , vol.6 , Issue.8
    • Biron, K.E.1    Dickstein, D.L.2    Gopaul, R.3    Jefferies, W.A.4
  • 6
    • 0029096047 scopus 로고
    • MR contrast due to intravascular magnetic susceptibility perturbations
    • Boxerman J.L., Hamberg L.M., Rosen B.R., Weisskoff R.M. MR contrast due to intravascular magnetic susceptibility perturbations. Magn. Reson. Med. 1995, 34(4):555-566.
    • (1995) Magn. Reson. Med. , vol.34 , Issue.4 , pp. 555-566
    • Boxerman, J.L.1    Hamberg, L.M.2    Rosen, B.R.3    Weisskoff, R.M.4
  • 7
    • 0041378074 scopus 로고    scopus 로고
    • Blood vessels and nerves: common signals, pathways and diseases
    • Carmeliet P. Blood vessels and nerves: common signals, pathways and diseases. Nat. Rev. Genet. 2003, 4(9):710-720.
    • (2003) Nat. Rev. Genet. , vol.4 , Issue.9 , pp. 710-720
    • Carmeliet, P.1
  • 8
    • 0036445830 scopus 로고    scopus 로고
    • Vascular and neuronal effects of VEGF in the nervous system: implications for neurological disorders
    • Carmeliet P., Storkebaum E. Vascular and neuronal effects of VEGF in the nervous system: implications for neurological disorders. Semin. Cell Dev. Biol. 2002, 13(1):39-53.
    • (2002) Semin. Cell Dev. Biol. , vol.13 , Issue.1 , pp. 39-53
    • Carmeliet, P.1    Storkebaum, E.2
  • 9
    • 0033560924 scopus 로고    scopus 로고
    • Characterization of progressive motor deficits in mice transgenic for the human Huntington's disease mutation
    • Carter R.J., Lione L.A., Humby T., Mangiarini L., Mahal A., Bates G.P., Dunnett S.B., Morton A.J. Characterization of progressive motor deficits in mice transgenic for the human Huntington's disease mutation. J. Neurosci. 1999, 19(8):3248-3257.
    • (1999) J. Neurosci. , vol.19 , Issue.8 , pp. 3248-3257
    • Carter, R.J.1    Lione, L.A.2    Humby, T.3    Mangiarini, L.4    Mahal, A.5    Bates, G.P.6    Dunnett, S.B.7    Morton, A.J.8
  • 11
    • 0037310260 scopus 로고    scopus 로고
    • Computerized quantification of tissue vascularization using high-resolution slide scanning of whole tumor sections
    • Chantrain C.F., DeClerck Y.A., Groshen S., McNamara G. Computerized quantification of tissue vascularization using high-resolution slide scanning of whole tumor sections. J. Histochem. Cytochem. 2003, 51(2):151-158.
    • (2003) J. Histochem. Cytochem. , vol.51 , Issue.2 , pp. 151-158
    • Chantrain, C.F.1    DeClerck, Y.A.2    Groshen, S.3    McNamara, G.4
  • 12
    • 83055194368 scopus 로고    scopus 로고
    • Complex relationships between cerebral blood flow and brain atrophy in early Huntington's disease
    • Chen J.J., Salat D.H., Rosas H.D. Complex relationships between cerebral blood flow and brain atrophy in early Huntington's disease. NeuroImage 2012, 59(2):1043-1051.
    • (2012) NeuroImage , vol.59 , Issue.2 , pp. 1043-1051
    • Chen, J.J.1    Salat, D.H.2    Rosas, H.D.3
  • 14
    • 69049091946 scopus 로고    scopus 로고
    • Alterations in cortical excitation and inhibition in genetic mouse models of Huntington's disease
    • Cummings D.M., Andre V.M., Uzgil B.O., Gee S.M., Fisher Y.E., Cepeda C., Levine M.S. Alterations in cortical excitation and inhibition in genetic mouse models of Huntington's disease. J. Neurosci. 2009, 29(33):10371-10386.
    • (2009) J. Neurosci. , vol.29 , Issue.33 , pp. 10371-10386
    • Cummings, D.M.1    Andre, V.M.2    Uzgil, B.O.3    Gee, S.M.4    Fisher, Y.E.5    Cepeda, C.6    Levine, M.S.7
  • 15
    • 34250623663 scopus 로고    scopus 로고
    • Blood-brain barrier pathology in Alzheimer's and Parkinson's disease: implications for drug therapy
    • Desai B.S., Monahan A.J., Carvey P.M., Hendey B. Blood-brain barrier pathology in Alzheimer's and Parkinson's disease: implications for drug therapy. Cell Transplant. 2007, 16(3):285-299.
    • (2007) Cell Transplant. , vol.16 , Issue.3 , pp. 285-299
    • Desai, B.S.1    Monahan, A.J.2    Carvey, P.M.3    Hendey, B.4
  • 16
    • 79960263505 scopus 로고    scopus 로고
    • Role of matrix metalloproteinase-9 (MMP-9) in striatal blood-brain barrier disruption in a 3-nitropropionic acid model of Huntington's disease
    • Duran-Vilaregut J., del Valle J., Manich G., Camins A., Pallas M., Vilaplana J., Pelegri C. Role of matrix metalloproteinase-9 (MMP-9) in striatal blood-brain barrier disruption in a 3-nitropropionic acid model of Huntington's disease. Neuropathol. Appl. Neurobiol. 2011, 37(5):525-537.
    • (2011) Neuropathol. Appl. Neurobiol. , vol.37 , Issue.5 , pp. 525-537
    • Duran-Vilaregut, J.1    del Valle, J.2    Manich, G.3    Camins, A.4    Pallas, M.5    Vilaplana, J.6    Pelegri, C.7
  • 17
    • 0035047718 scopus 로고    scopus 로고
    • Cerebral microvascular pathology in aging and Alzheimer's disease
    • Farkas E., Luiten P.G. Cerebral microvascular pathology in aging and Alzheimer's disease. Prog. Neurobiol. 2001, 64(6):575-611.
    • (2001) Prog. Neurobiol. , vol.64 , Issue.6 , pp. 575-611
    • Farkas, E.1    Luiten, P.G.2
  • 18
    • 81955167911 scopus 로고    scopus 로고
    • Age-dependent neurovascular abnormalities and altered microglial morphology in the YAC128 mouse model of Huntington disease
    • Franciosi S., Ryu J.K., Shim Y., Hill A., Connolly C., Hayden M.R., McLarnon J.G., Leavitt B.R. Age-dependent neurovascular abnormalities and altered microglial morphology in the YAC128 mouse model of Huntington disease. Neurobiol. Dis. 2012, 45(1):438-449.
    • (2012) Neurobiol. Dis. , vol.45 , Issue.1 , pp. 438-449
    • Franciosi, S.1    Ryu, J.K.2    Shim, Y.3    Hill, A.4    Connolly, C.5    Hayden, M.R.6    McLarnon, J.G.7    Leavitt, B.R.8
  • 19
    • 33645523000 scopus 로고    scopus 로고
    • Small vessels, big problems
    • Greenberg S.M. Small vessels, big problems. N. Engl. J. Med. 2006, 354(14):1451-1453.
    • (2006) N. Engl. J. Med. , vol.354 , Issue.14 , pp. 1451-1453
    • Greenberg, S.M.1
  • 20
    • 0032860404 scopus 로고    scopus 로고
    • Reduced basal ganglia blood flow and volume in pre-symptomatic, gene-tested persons at-risk for Huntington's disease
    • Harris G.J., Codori A.M., Lewis R.F., Schmidt E., Bedi A., Brandt J. Reduced basal ganglia blood flow and volume in pre-symptomatic, gene-tested persons at-risk for Huntington's disease. Brain 1999, 122(Pt 9):1667-1678.
    • (1999) Brain , vol.122 , Issue.PART 9 , pp. 1667-1678
    • Harris, G.J.1    Codori, A.M.2    Lewis, R.F.3    Schmidt, E.4    Bedi, A.5    Brandt, J.6
  • 21
    • 79551623131 scopus 로고    scopus 로고
    • Increased prothrombin, apolipoprotein A-IV, and haptoglobin in the cerebrospinal fluid of patients with Huntington's disease
    • Huang Y.C., Wu Y.R., Tseng M.Y., Chen Y.C., Hsieh S.Y., Chen C.M. Increased prothrombin, apolipoprotein A-IV, and haptoglobin in the cerebrospinal fluid of patients with Huntington's disease. PLoS One 2011, 6(1):e15809.
    • (2011) PLoS One , vol.6 , Issue.1
    • Huang, Y.C.1    Wu, Y.R.2    Tseng, M.Y.3    Chen, Y.C.4    Hsieh, S.Y.5    Chen, C.M.6
  • 22
    • 77953405595 scopus 로고    scopus 로고
    • Differentiation of the brain vasculature: the answer came blowing by the Wnt
    • Liebner S., Plate K.H. Differentiation of the brain vasculature: the answer came blowing by the Wnt. J. Angiogenes. Res. 2010, 2:1.
    • (2010) J. Angiogenes. Res. , vol.2 , pp. 1
    • Liebner, S.1    Plate, K.H.2
  • 23
    • 61649120559 scopus 로고    scopus 로고
    • In vivo cerebromicrovasculatural visualization using 3D DeltaR2-based microscopy of magnetic resonance angiography (3DDeltaR2-mMRA)
    • Lin C.Y., Lin M.H., Cheung W.M., Lin T.N., Chen J.H., Chang C. In vivo cerebromicrovasculatural visualization using 3D DeltaR2-based microscopy of magnetic resonance angiography (3DDeltaR2-mMRA). NeuroImage 2009, 45(3):824-831.
    • (2009) NeuroImage , vol.45 , Issue.3 , pp. 824-831
    • Lin, C.Y.1    Lin, M.H.2    Cheung, W.M.3    Lin, T.N.4    Chen, J.H.5    Chang, C.6
  • 26
    • 42149161677 scopus 로고    scopus 로고
    • Altered morphology and 3D architecture of brain vasculature in a mouse model for Alzheimer's disease
    • Meyer E.P., Ulmann-Schuler A., Staufenbiel M., Krucker T. Altered morphology and 3D architecture of brain vasculature in a mouse model for Alzheimer's disease. Proc. Natl. Acad. Sci. U. S. A. 2008, 105(9):3587-3592.
    • (2008) Proc. Natl. Acad. Sci. U. S. A. , vol.105 , Issue.9 , pp. 3587-3592
    • Meyer, E.P.1    Ulmann-Schuler, A.2    Staufenbiel, M.3    Krucker, T.4
  • 27
    • 14944354691 scopus 로고    scopus 로고
    • Gadolinium-enhanced small-animal TOF magnetic resonance angiography
    • Miraux S., Serres S., Thiaudiere E., Canioni P., Merle M., Franconi J.M. Gadolinium-enhanced small-animal TOF magnetic resonance angiography. MAGMA 2004, 17(3-6):348-352.
    • (2004) MAGMA , vol.17 , Issue.3-6 , pp. 348-352
    • Miraux, S.1    Serres, S.2    Thiaudiere, E.3    Canioni, P.4    Merle, M.5    Franconi, J.M.6
  • 28
    • 0028026635 scopus 로고
    • Architectural alterations in rat cerebral microvessels after hypobaric hypoxia
    • Mironov V., Hritz M.A., LaManna J.C., Hudetz A.G., Harik S.I. Architectural alterations in rat cerebral microvessels after hypobaric hypoxia. Brain Res. 1994, 660(1):73-80.
    • (1994) Brain Res. , vol.660 , Issue.1 , pp. 73-80
    • Mironov, V.1    Hritz, M.A.2    LaManna, J.C.3    Hudetz, A.G.4    Harik, S.I.5
  • 30
    • 33644531897 scopus 로고    scopus 로고
    • Brain imaging and cognitive dysfunctions in Huntington's disease
    • Montoya A., Price B.H., Menear M., Lepage M. Brain imaging and cognitive dysfunctions in Huntington's disease. J. Psychiatr. Neurosci. 2006, 31(1):21-29.
    • (2006) J. Psychiatr. Neurosci. , vol.31 , Issue.1 , pp. 21-29
    • Montoya, A.1    Price, B.H.2    Menear, M.3    Lepage, M.4
  • 31
    • 77956069555 scopus 로고    scopus 로고
    • Huntington's disease
    • Novak M.J., Tabrizi S.J. Huntington's disease. BMJ 2010, 340:c3109.
    • (2010) BMJ , vol.340
    • Novak, M.J.1    Tabrizi, S.J.2
  • 32
    • 0027263961 scopus 로고
    • Functional brain mapping by blood oxygenation level-dependent contrast magnetic resonance imaging. A comparison of signal characteristics with a biophysical model
    • Ogawa S., Menon R.S., Tank D.W., Kim S.G., Merkle H., Ellermann J.M., Ugurbil K. Functional brain mapping by blood oxygenation level-dependent contrast magnetic resonance imaging. A comparison of signal characteristics with a biophysical model. Biophys. J. 1993, 64(3):803-812.
    • (1993) Biophys. J. , vol.64 , Issue.3 , pp. 803-812
    • Ogawa, S.1    Menon, R.S.2    Tank, D.W.3    Kim, S.G.4    Merkle, H.5    Ellermann, J.M.6    Ugurbil, K.7
  • 33
    • 77953533246 scopus 로고    scopus 로고
    • Cerebral small vessel disease: from pathogenesis and clinical characteristics to therapeutic challenges
    • Pantoni L. Cerebral small vessel disease: from pathogenesis and clinical characteristics to therapeutic challenges. Lancet Neurol. 2010, 9(7):689-701.
    • (2010) Lancet Neurol. , vol.9 , Issue.7 , pp. 689-701
    • Pantoni, L.1
  • 35
    • 0028944747 scopus 로고
    • A computerized method for determination of microvascular density
    • Rieder M.J., O'Drobinak D.M., Greene A.S. A computerized method for determination of microvascular density. Microvasc. Res. 1995, 49(2):180-189.
    • (1995) Microvasc. Res. , vol.49 , Issue.2 , pp. 180-189
    • Rieder, M.J.1    O'Drobinak, D.M.2    Greene, A.S.3
  • 36
    • 57449088803 scopus 로고    scopus 로고
    • Use of magnetic resonance imaging for anatomical phenotyping of the R6/2 mouse model of Huntington's disease
    • Sawiak S.J., Wood N.I., Williams G.B., Morton A.J., Carpenter T.A. Use of magnetic resonance imaging for anatomical phenotyping of the R6/2 mouse model of Huntington's disease. Neurobiol. Dis. 2009, 33(1):12-19.
    • (2009) Neurobiol. Dis. , vol.33 , Issue.1 , pp. 12-19
    • Sawiak, S.J.1    Wood, N.I.2    Williams, G.B.3    Morton, A.J.4    Carpenter, T.A.5
  • 37
    • 0031034033 scopus 로고    scopus 로고
    • Normal perfusion pressure breakthrough: the role of capillaries
    • Sekhon L.H., Morgan M.K., Spence I. Normal perfusion pressure breakthrough: the role of capillaries. J. Neurosurg. 1997, 86(3):519-524.
    • (1997) J. Neurosurg. , vol.86 , Issue.3 , pp. 519-524
    • Sekhon, L.H.1    Morgan, M.K.2    Spence, I.3
  • 38
    • 56749104928 scopus 로고    scopus 로고
    • Canonical Wnt signaling regulates organ-specific assembly and differentiation of CNS vasculature
    • Stenman J.M., Rajagopal J., Carroll T.J., Ishibashi M., McMahon J., McMahon A.P. Canonical Wnt signaling regulates organ-specific assembly and differentiation of CNS vasculature. Science 2008, 322(5905):1247-1250.
    • (2008) Science , vol.322 , Issue.5905 , pp. 1247-1250
    • Stenman, J.M.1    Rajagopal, J.2    Carroll, T.J.3    Ishibashi, M.4    McMahon, J.5    McMahon, A.P.6
  • 39
    • 4644234505 scopus 로고    scopus 로고
    • VEGF: once regarded as a specific angiogenic factor, now implicated in neuroprotection
    • Storkebaum E., Lambrechts D., Carmeliet P. VEGF: once regarded as a specific angiogenic factor, now implicated in neuroprotection. Bioessays 2004, 26(9):943-954.
    • (2004) Bioessays , vol.26 , Issue.9 , pp. 943-954
    • Storkebaum, E.1    Lambrechts, D.2    Carmeliet, P.3
  • 40
    • 0026011540 scopus 로고
    • Measurement of the blood-brain barrier permeability and leakage space using dynamic MR imaging. 1. Fundamental concepts
    • Tofts P.S., Kermode A.G. Measurement of the blood-brain barrier permeability and leakage space using dynamic MR imaging. 1. Fundamental concepts. Magn. Reson. Med. 1991, 17(2):357-367.
    • (1991) Magn. Reson. Med. , vol.17 , Issue.2 , pp. 357-367
    • Tofts, P.S.1    Kermode, A.G.2
  • 41
    • 30644465969 scopus 로고    scopus 로고
    • Vascular remodeling versus amyloid beta-induced oxidative stress in the cerebrovascular dysfunctions associated with Alzheimer's disease
    • Tong X.K., Nicolakakis N., Kocharyan A., Hamel E. Vascular remodeling versus amyloid beta-induced oxidative stress in the cerebrovascular dysfunctions associated with Alzheimer's disease. J. Neurosci. 2005, 25(48):11165-11174.
    • (2005) J. Neurosci. , vol.25 , Issue.48 , pp. 11165-11174
    • Tong, X.K.1    Nicolakakis, N.2    Kocharyan, A.3    Hamel, E.4
  • 45
    • 0037380109 scopus 로고    scopus 로고
    • High-resolution in vivo CBV mapping with MRI in wild-type mice
    • Wu E.X., Wong K.K., Andrassy M., Tang H. High-resolution in vivo CBV mapping with MRI in wild-type mice. Magn. Reson. Med. 2003, 49(4):765-770.
    • (2003) Magn. Reson. Med. , vol.49 , Issue.4 , pp. 765-770
    • Wu, E.X.1    Wong, K.K.2    Andrassy, M.3    Tang, H.4
  • 47
    • 39449111508 scopus 로고    scopus 로고
    • Neurovascular signalling defects in neurodegeneration
    • Zacchigna S., Lambrechts D., Carmeliet P. Neurovascular signalling defects in neurodegeneration. Nat. Rev. Neurosci. 2008, 9(3):169-181.
    • (2008) Nat. Rev. Neurosci. , vol.9 , Issue.3 , pp. 169-181
    • Zacchigna, S.1    Lambrechts, D.2    Carmeliet, P.3
  • 49
    • 71849109192 scopus 로고    scopus 로고
    • Longitudinal characterization of brain atrophy of a Huntington's disease mouse model by automated morphological analyses of magnetic resonance images
    • Zhang J., Peng Q., Li Q., Jahanshad N., Hou Z., Jiang M., Masuda N., Langbehn D.R., Miller M.I., Mori S., Ross C.A., Duan W. Longitudinal characterization of brain atrophy of a Huntington's disease mouse model by automated morphological analyses of magnetic resonance images. NeuroImage 2010, 49(3):2340-2351.
    • (2010) NeuroImage , vol.49 , Issue.3 , pp. 2340-2351
    • Zhang, J.1    Peng, Q.2    Li, Q.3    Jahanshad, N.4    Hou, Z.5    Jiang, M.6    Masuda, N.7    Langbehn, D.R.8    Miller, M.I.9    Mori, S.10    Ross, C.A.11    Duan, W.12
  • 50
    • 13544268809 scopus 로고    scopus 로고
    • Neurovascular mechanisms of Alzheimer's neurodegeneration
    • Zlokovic B.V. Neurovascular mechanisms of Alzheimer's neurodegeneration. Trends Neurosci. 2005, 28(4):202-208.
    • (2005) Trends Neurosci. , vol.28 , Issue.4 , pp. 202-208
    • Zlokovic, B.V.1
  • 51
    • 38149090292 scopus 로고    scopus 로고
    • The blood-brain barrier in health and chronic neurodegenerative disorders
    • Zlokovic B.V. The blood-brain barrier in health and chronic neurodegenerative disorders. Neuron 2008, 57(2):178-201.
    • (2008) Neuron , vol.57 , Issue.2 , pp. 178-201
    • Zlokovic, B.V.1


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