NMR-based conformational ensembles explain pH-gated opening and closing of OmpG channel

Journal of the American Chemical Society

Volumn 135, Issue 40, 2013, Pages 15101-15113

  Zhuang, Tiandi ^a   Chisholm, Christina ^b   Chen, Min ^b   Tamm, Lukas K ^a  

^a UNIVERSITY OF VIRGINIA   (United States)

^b UNIVERSITY OF MASSACHUSETTS   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

AMINO ACIDS; ELECTROPHYSIOLOGY; ESCHERICHIA COLI; MICELLES; SULFUR COMPOUNDS;

CONFORMATIONAL DYNAMICS; CONFORMATIONAL ENSEMBLE; CONFORMATIONAL EXCHANGE; DISULFIDE CROSS-LINKING; EXTRACELLULAR LOOPS; OUTER MEMBRANE PROTEIN; PARAMAGNETIC RELAXATION ENHANCEMENTS; SINGLE CHANNEL RECORDING;

PROTEINS;

CYSTEINE; DISULFIDE; OLIGOSACCHARIDE; OUTER MEMBRANE PROTEIN; OUTER MEMBRANE PROTEIN G; UNCLASSIFIED DRUG;

ANALYTIC METHOD; ARTICLE; CHANNEL GATING; CONTROLLED STUDY; CROSS LINKING; CRYSTAL STRUCTURE; ESCHERICHIA COLI; MASS SPECTROMETRY; MICELLE; NONHUMAN; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY; PARAMAGNETIC RELAXATION ENHANCEMENT; PH; PROTEIN CONFORMATION; TITRIMETRY;

BACTERIAL OUTER MEMBRANE PROTEINS; DISULFIDES; ESCHERICHIA COLI PROTEINS; HYDROGEN-ION CONCENTRATION; ION CHANNEL GATING; MAGNETIC RESONANCE SPECTROSCOPY; MICELLES; MOLECULAR DYNAMICS SIMULATION; MUTAGENESIS, SITE-DIRECTED; MUTATION; PHOSPHORYLCHOLINE; PORINS; PROTEIN CONFORMATION;

EID: 84885666400     PISSN: 00027863     EISSN: 15205126     Source Type: Journal    
DOI: 10.1021/ja408206e     Document Type: Article

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