Association between vitamin D and hepatitis C virus infection: A meta-analysis

World Journal of Gastroenterology

Volumn 19, Issue 35, 2013, Pages 5917-5924

  Villar, Livia Melo ^a   Del Campo, José Antonio ^b   Ranchal, Isidora ^b   Lampe, Elisabeth ^a   Romero Gomez, Manuel ^b  

^a INSTITUTO OSWALDO CRUZ   (Brazil)

^b HOSPITAL UNIVERSITARIO DE VALME   (Spain)

Author keywords

Hepatitis C; Metaanalysis; Sustained virological response; Therapy; Vitamin D

Indexed keywords

25 HYDROXYVITAMIN D;

ANTIVIRAL THERAPY; ARTICLE; CHEMOLUMINESCENCE; GENOTYPE; HEPATITIS C; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; HUMAN; HUMAN IMMUNODEFICIENCY VIRUS INFECTION; META ANALYSIS; MICROBIOLOGICAL PARAMETERS; QUALITY CONTROL; RADIOIMMUNOASSAY; SUSTAINED VIROLOGICAL RESPONSE; SYSTEMATIC REVIEW; VIRUS LOAD; VITAMIN D DEFICIENCY; VITAMIN SUPPLEMENTATION;

HEPATITIS C; META-ANALYSIS; SUSTAINED VIROLOGICAL RESPONSE; THERAPY; VITAMIN D;

25-HYDROXYVITAMIN D 2; ADULT; ANTIVIRAL AGENTS; BIOLOGICAL MARKERS; CALCIFEDIOL; CHI-SQUARE DISTRIBUTION; DIETARY SUPPLEMENTS; HEPATITIS C; HUMANS; MIDDLE AGED; ODDS RATIO; PREVALENCE; RISK FACTORS; TREATMENT OUTCOME; VIRAL LOAD; VITAMIN D DEFICIENCY;

EID: 84885659062     PISSN: 10079327     EISSN: 22192840     Source Type: Journal    
DOI: 10.3748/wjg.v19.i35.5917     Document Type: Article

References (36)

1. Lavanchy D. Evolving epidemiology of hepatitis C virus. Clin Microbiol Infect 2011; 17: 107-115 [PMID: 21091831 DOI: 10.1111/j.1469-0691.2010.03432.x]
2. Klenerman P, Gupta PK. Hepatitis C virus: current concepts and future challenges. QJM 2012; 105: 29-32 [PMID: 22123990 DOI: 10.1093/qjmed/hcr231]
3. Romero-Gomez M, Eslam M, Ruiz A, Maraver M. Genes and hepatitis C: susceptibility, fibrosis progression and response to treatment. Liver Int 2011; 31: 443-460 [PMID: 21382156 DOI: 10.1111/j.1478-3231.2011.02449.x]
4. Eslam M, Aparcero R, Kawaguchi T, Del Campo JA, Sata M, Khattab MA, Romero-Gomez M. Meta-analysis: insulin resistance and sustained virological response in hepatitis C. Aliment Pharmacol Ther 2011; 34: 297-305 [PMID: 21623851 DOI: 10.1111/j.1365-2036.2011.04716.x]
5. de Rueda PM, López-Nevot MÁ, Sáenz-López P, Casado J, Martín-Casares A, Palomares P, Quiles R, Gila A, Romero-Gómez M, Pavón EJ, Muñoz JA, Carazo A, Sanz-Cameno P, Moreno-Otero R, Diago M, León J, Ruiz-Extremera A, Salmerón J. Importance of host genetic factors HLA and IL28B as predictors of response to pegylated interferon and ribavirin. Am J Gastroenterol 2011; 106: 1246-1254 [PMID: 21670772 DOI: 10.1038/ajg.2011.82]
6. Cholangitis E, Theocharidou E, Goulis J, Tsochatzis E, Akriviadis E, Burroughs K. Review article: the extra-skeletal effects of vitamin D in chronic hepatitis C infection. Aliment Pharmacol Ther 2012; 35: 634-646 [PMID: 22316435 DOI: 10.1111/j.1365-2036.2012.05000.x]
7. Fleet JC, DeSmet M, Johnson R, Li Y. Vitamin D and cancer: a review of molecular mechanisms. Biochem J 2012; 441: 61-76 [PMID: 22168439 DOI: 10.1042/BJ20110744]
8. Lai JK, Lucas RM, Banks E, Ponsonby AL. Variability in vitamin D assays impairs clinical assessment of vitamin D status. Intern Med J 2012; 42: 43-50 [PMID: 21395958 DOI: 10.1111/j.1445-5994.2011.02471.x]
9. Haines ST, Park SK. Vitamin D supplementation: what' s known, what to do, and what's needed. Pharmacotherapy 2012; 32: 354-382 [PMID: 22461123 DOI: 10.1002/phar.1037]
10. McGrath JJ, Saha S, Burne TH, Eyles DW. A systematic review of the association between common single nucleotide polymorphisms and 25-hydroxyvitamin D concentrations. J Steroid Biochem Mol Biol 2010; 121: 471-477 [PMID: 20363324 DOI: 10.1016/j.jsbmb.2010.03.073]
11. Norton R, O'Connell MA. Vitamin D: potential in the prevention and treatment of lung cancer. Anticancer Res 2012; 32: 211-221 [PMID: 22213310]
12. McGreevy C, Williams D. New insights about vitamin D and cardiovascular disease: a narrative review. Ann Intern Med 2011; 155: 820-826 [PMID: 22184689 DOI: 10.1059/0003-4819-155-12-201112200-00004]
13. Artaza JN, Contreras S, Garcia LA, Mehrotra R, Gibbons G, Shohet R, Martins D, Norris KC. Vitamin D and cardiovascular disease: potential role in health disparities. J Health Care Poor Underserved 2011; 22: 23-38 [PMID: 22102304 DOI: 10.1353/hpu.2011.0161]
14. Pender MP. CD8+ T-Cell Deficiency, Epstein-Barr Virus Infection, Vitamin D Deficiency, and Steps to Autoimmunity: A Unifying Hypothesis. Autoimmune Dis 2012; 2012: 189096 [PMID: 22312480 DOI: 10.1155/2012/189096]
15. Van Belle TL, Gysemans C, Mathieu C. Vitamin D in autoimmune, infectious and allergic diseases: a vital player? Best Pract Res Clin Endocrinol Metab 2011; 25: 617-632 [PMID: 21872803 DOI: 10.1016/j.beem.2011.04.009]
16. Childs K, Welz T, Samarawickrama A, Post FA. Effects of vitamin D deficiency and combination antiretroviral therapy on bone in HIV-positive patients. AIDS 2012; 26: 253-262 [PMID: 22112601 DOI: 10.1097/QAD.0b013e32834f324b]
17. Petta S, Cammà C, Scazzone C, Tripodo C, Di Marco V, Bono A, Cabibi D, Licata G, Porcasi R, Marchesini G, Craxí A. Low vitamin D serum level is related to severe fibrosis and low responsiveness to interferon-based therapy in genotype 1 chronic hepatitis C. Hepatology 2010; 51: 1158-1167 [PMID: 20162613]
18. Lange CM, Bojunga J, Ramos-Lopez E, von Wagner M, Hassler A, Vermehren J, Herrmann E, Badenhoop K, Zeuzem S, Sarrazin C. Vitamin D deficiency and a CYP27B1-1260 promoter polymorphism are associated with chronic hepatitis C and poor response to interferon-alfa based therapy. J Hepatol 2011; 54: 887-893 [PMID: 21145801 DOI: 10.1016/ j.jhep.2010.08.036]
19. Nseir W, Gali M, Mouch SA, Djibre A, Nassar F, Assy N. Baseline serum HDL and vitamin D levels are strongly associated with SVR in chronic hepatitis C naïve genotype 1 patients. J Hepatol 2011; 54: S450
20. Bitetto D, Fabris C, Fornasiere E, Pipan C, Fumolo E, Cussigh A, Bignulin S, Cmet S, Fontanini E, Falleti E, Martinella R, Pirisi M, Toniutto P. Vitamin D supplementation improves response to antiviral treatment for recurrent hepatitis C. Transpl Int 2011; 24: 43-50 [PMID: 20649944 DOI: 10.1111/ j.1432-2277.2010.01141.x]
21. Bitetto D, Fattovich G, Fabris C, Ceriani E, Falleti E, Fornasiere E, Pasino M, Ieluzzi D, Cussigh A, Cmet S, Pirisi M, Toniutto P. Complementary role of vitamin D deficiency and the interleukin-28B rs12979860 C/T polymorphism in predicting antiviral response in chronic hepatitis C. Hepatology 2011; 53: 1118-1126 [PMID: 21480318 DOI: 10.1002/ hep.24201]
22. Terrier B, Carrat F, Geri G, Pol S, Piroth L, Halfon P, Poynard T, Souberbielle JC, Cacoub P. Low 25-OH vitamin D serum levels correlate with severe fibrosis in HIV-HCV coinfected patients with chronic hepatitis. J Hepatol 2011; 55: 756-761 [PMID: 21334402 DOI: 10.1016/j.jhep.2011.01.041]
23. Jazwinski A, Clark PJ, Tillmann HL, Muir AJ. Vitamin D and treatment response in African American patients with HCV genotype 1. Hepatology 2011; 54: 853
24. Zamora J, Abraira V, Muriel A, Khan K, Coomarasamy A. Meta-DiSc: a software for meta-analysis of test accuracy data. BMC Med Res Methodol 2006; 6: 31 [PMID: 16836745]
25. Milazzo L, Mazzali C, Bestetti G, Longhi E, Foschi A, Viola A, Vago T, Galli M, Parravicini C, Antinori S. Liver-related factors associated with low vitamin D levels in HIV and HIV/HCV coinfected patients and comparison to general population. Curr HIV Res 2011; 9: 186-193 [PMID: 21585333]
26. Nimer A, Mouch A. Vitamin D improves viral response in hepatitis C genotype 2-3 naïve patients. World J Gastroenterol 2012; 18: 800-805 [PMID: 22371640 DOI: 10.3748/wjg.v18. i8.800]
27. Abu-Mouch S, Fireman Z, Jarchovsky J, Zeina AR, Assy N. Vitamin D supplementation improves sustained virologic response in chronic hepatitis C (genotype 1)-naïve patients. World J Gastroenterol 2011; 17: 5184-5190 [PMID: 22215943 DOI: 10.3748/wjg.v17.i47.5184]
28. Soumekh A, Bichoupan K, Constable C, Benedict P, Vachon MLC, Fiel MI, Brau N, Rodriguez-Torres M, Sterling RK, Talal A, Sulkowski MS, Woodward M, Dieterich DT, Branch AD. Two novel findings about interferon/ribavirin treatment: serum calcium falls and 25-hydroxyvitamin D increases. Hepatology 2011; 54: 856
29. Reiberg T, Payer BA, Obermayer-Pietsch B, Rieger A, Peck-Radosavljevic M. 1,25-OH-vitamin D levels are associated with early viral kinetics and sustained virologic response in patients with HCV-HIV coinfection. Hepatology 2011; 54: 1191-1192
30. DeLuca HF. Overview of general physiologic features and functions of vitamin D. Am J Clin Nutr 2004; 80: 1689S-1696S [PMID: 15585789]
31. Arteh J, Narra S, Nair S. Prevalence of vitamin D deficiency in chronic liver disease. Dig Dis Sci 2010; 55: 2624-2628 [PMID: 19960254 DOI: 10.1007/s10620-009-1069-9]
32. Putz-Bankuti C, Pilz S, Stojakovic T, Scharnagl H, Pieber TR, Trauner M, Obermayer-Pietsch B, Stauber RE. Association of 25-hydroxyvitamin D levels with liver dysfunction and mortality in chronic liver disease. Liver Int 2012; 32: 845-851 [PMID: 22222013 DOI: 10.1111/j.1478-3231.2011.02735.x]
33. Baur K, Mertens JC, Schmitt J, Iwata R, Stieger B, Eloranta JJ, Frei P, Stickel F, Dill MT, Seifert B, Ferrari HA, von Eckardstein A, Bochud PY, Müllhaupt B, Geier A. Combined effect of 25-OH vitamin D plasma levels and genetic vitamin D receptor (NR 1I1) variants on fibrosis progression rate in HCV patients. Liver Int 2012; 32: 635-643 [PMID: 22151003 DOI: 10.1111/j.1478-3231.2011.02674.x]
34. Gal-Tanamy M, Bachmetov L, Ravid A, Koren R, Erman A, Tur-Kaspa R, Zemel R. Vitamin D: an innate antiviral agent suppressing hepatitis C virus in human hepatocytes. Hepatology 2011; 54: 1570-1579 [PMID: 21793032 DOI: 10.1002/ hep.24575]
35. Dusso AS, Brown AJ, Slatopolsky E. Vitamin D. Am J Physiol Renal Physiol 2005; 289: F8-28 [PMID: 15951480]
36. Ge D, Fellay J, Thompson AJ, Simon JS, Shianna KV, Urban TJ, Heinzen EL, Qiu P, Bertelsen AH, Muir AJ, Sulkowski M, McHutchison JG, Goldstein DB. Genetic variation in IL28B predicts hepatitis C treatment-induced viral clearance. Nature 2009; 461: 399-401 [PMID: 19684573 DOI: 10.1038/nature08309]