Liver-related factors associated with low vitamin D levels in HIV and HIV/HCV coinfected patients and comparison to general population

Current HIV Research

Volumn 9, Issue 3, 2011, Pages 186-193

  Milazzo, Laura ^a   Mazzali, Cristina ^b   Bestetti, Giovanna ^a   Longhi, Erika ^a   Foschi, Antonella ^a   Viola, Anita ^a   Vago, Tarcisio ^a   Galli, Massimo ^a   Parravicini, Carlo ^a   Antinori, Spinello ^a  

^a UNIVERSITY OF MILAN   (Italy)

^b UNIVERSITY OF MILAN   (Italy)

Author keywords

25 hydroxyvitamin D insufficiency; CYP27A1; CYP2R1; HIV; HIV HCV coinfection; Liver fibrosis

Indexed keywords

25 HYDROXYVITAMIN D; ANTIRETROVIRUS AGENT; CHOLESTANETRIOL 26 MONOOXYGENASE; CYTOCHROME P450; CYTOCHROME P450 2R1; LIVER ENZYME; NONNUCLEOSIDE REVERSE TRANSCRIPTASE INHIBITOR; PEGINTERFERON; PROTEINASE INHIBITOR; RIBAVIRIN; TENOFOVIR; UNCLASSIFIED DRUG; VITAMIN D;

ADULT; ARTICLE; COHORT ANALYSIS; CONTROLLED STUDY; CORRELATION ANALYSIS; FEMALE; HEPATITIS C; HIGHLY ACTIVE ANTIRETROVIRAL THERAPY; HUMAN; HUMAN IMMUNODEFICIENCY VIRUS INFECTION; HUMAN TISSUE; IMMUNE RESPONSE; IMMUNOHISTOCHEMISTRY; LIVER DISEASE; LIVER FIBROSIS; MAJOR CLINICAL STUDY; MALE; MIXED INFECTION; MULTIPLE REGRESSION; PROTEIN EXPRESSION; SEASONAL VARIATION; SUSTAINED VIROLOGICAL RESPONSE; VITAMIN BLOOD LEVEL; VITAMIN D DEFICIENCY;

ADULT; ANTIVIRAL AGENTS; FEMALE; HEPATITIS C, CHRONIC; HIV INFECTIONS; HUMANS; INTERFERONS; LIVER; MALE; MIDDLE AGED; RETROSPECTIVE STUDIES; RIBAVIRIN; VITAMIN D; VITAMIN D DEFICIENCY;

EID: 79959319615     PISSN: 1570162X     EISSN: 18734251     Source Type: Journal    
DOI: 10.2174/157016211795945269     Document Type: Article

References (36)

1. Holick MF. Vitamin D: extraskeletal health. Endocrinol Metab Clin North Am 2010; 39: 381-400.
2. Chiu KC, Chu A, Go V, Saad MF. Hypovitaminosis D is associated with insulin resistance and b cell dysfunction. Am J Clin Nutr 2004; 79: 820-25.
3. Schiefke I, Fach A, Wiedmann M, et al. Reduced bone mineral density and altered bone turnover markers in patients with noncirrhotic chronic hepatitis B or C infection. World J Gastroenterol 2005; 11: 1843-47.
4. Collier J. Bone disorders in chronic liver disease. Hepatology 2007; 46: 1271-78.
5. Fisher L, Fisher A. Vitamin D and parathyroid hormone in outpatients with noncholestatic chronic liver disease. Clin Gastroenterol Hepatol 2007; 5: 513-20.
6. Giovannucci E, Liu Y, Willett WC. Cancer incidence and mortality and vitamin D in black and white male health professionals. Cancer Epidemiol Biomarkers Prev 2006; 15: 2467-72.
7. Pfeifer M, Begerow B, Minne HW, Nachtigall D, Hansen C. Effects of a short-term vitamin D(3) and calcium supplementation on blood pressure and parathyroid hormone levels in elderly women. J Clin Endocrinol Metab 2001; 86: 1633-37.
8. Suneetha PV, Sarin SK, Goyal A, Kumar GT, Shukla DK, Hissar S. Association between vitamin D receptor, CCR5, TNF-alpha and TNF-beta gene polymorphisms and HBV infection and severity of liver disease. J Hepatol 2006; 44: 856-63.
9. Holick MF. Vitamin D deficiency. N Engl J Med 2007; 357: 266-281.
10. Villamor E. A potential role for vitamin D on HIV infection? Nutr Rev 2006; 64: 226-33.
11. Rodriguez M, Daniels B, Gunawardene S, Robbins GK. High frequency of vitamin D deficiency in ambulatory HIV-positive patients. AIDS Res Hum Retroviruses 2009; 25: 9-14.
12. Van Den Bout-Van Den Beukel CJ, Fievez L, Michels M, et al. Vitamin D deficiency among HIV type 1-infected individuals in the Netherlands: effects of antiretroviral therapy. AIDS Res Hum Retroviruses 2008; 24: 1375-82.
13. Stephensen CB, Marquis GS, Kruzich LA, Douglas SD, Aldrovandi GM, Wilson CM. Vitamin D status in adolescents and young adults with HIV infection. Am J Clin Nutr 2006; 83: 1135-1141.
14. Mueller NJ, Fux CA, Ledergerber B, et al. Swiss HIV Cohort Study. High prevalence of severe vitamin D deficiency in combined antiretroviral therapy-naive and successfully treated Swiss HIV patients. AIDS 2010; 24: 1127-34.
15. Fox J, Peters B, Prakash M, Arribas J, Hill A, Moecklinghoff C. Improvement in Vitamin D Deficiency Following Antiretroviral Regime Change: Results from the MONET Trial. AIDS Res Hum Retroviruses 2011: 27: 29-34.
16. Petta S, Cammà C, Scazzone C, et al. Low vitamin D serum level is related to severe fibrosis and low responsiveness to interferonbased therapy in genotype 1 chronic hepatitis C. Hepatology 2010; 51: 1158-67.
17. Vallet-Pichard A, Mallet V, Nalpas B, et al. FIB-4: an inexpensive and accurate marker of fibrosis in HCV infection. comparison with liver biopsy and fibrotest. Hepatology 2007; 46: 32-6.
18. Bischoff-Ferrari HA, Giovannucci E, Willett WC, Dietrich T, Dawson-Hughes B. Estimation of optimal serum concentrations of 25-hydroxyvitamin D for multiple health outcomes. Am J Clin Nutr 2006; 84: 18-28.
19. Knodell RG, Ishak KG, Black WC et al. Formulation and application of a numerical scoring system for assessing histological activity in asymptomatic chronic active hepatitis. Hepatology 1981; 1: 431-35.
20. Calmy A, Fux CA, Norris R, et al. Low bone mineral density, renal dysfunction, and fracture risk in HIV infection: a cross-sectional study. J Infect Dis 2009; 200: 1746-54.
21. Welz T, Childs K, Ibrahim F, et al. Efavirenz is associated with severe vitamin D deficiency and increased alkaline phosphatise. AIDS 2010; 24: 1923-8.
22. Dao CN, Patel P, Overton ET, et al. Low vitamin D among HIVinfected adults: prevalence of and risk factors for low vitamin D Levels in a cohort of HIV-infected adults and comparison to prevalence among adults in the US general population. Clin Infect Dis 2011; 52: 396-405.
23. Pasquet A, Viget N, Ajana F, et al. Vitamin D deficiency in HIVinfected patients: associated with non-nucleoside reverse transcriptase inhibitor or efavirenz use? AIDS 2011; 25: 873-4.
24. Welz T, Childs K, Post FA. Do nevirapine and efavirenz affect vitamin D homeostasis similarly? AIDS 2011; 25: 875-6.
25. Fux CA, Baumann S, Furrer H, Mueller NJ. Is lower serum 25- hydroxy vitamin D associated with efavirenz or the non-nucleoside reverse transcriptase inhibitor class? AIDS 2011; 25: 876-8.
26. Lardner E, Fitzgibbon M, Wilson S, Griffin D, Mulkerrin E. Hypovitaminosis D in a healthy female population, aged from 40 to 85 years, in the west of Ireland. Ir J Med Sci 2011; 180: 115-9.
27. Melamed ML, Michos ED, Post W, Astor B. 25-hydroxyvitamin D levels and the risk of mortality in the general population. Arch Intern Med 2008; 168: 1629-37.
28. Hyppönen E, Power C. Hypovitaminosis D in British adults at age 45 y: nationwide cohort study of dietary and lifestyle predictors. Am J Clin Nutr 2007; 85: 860-68.
29. Zittermann A. Vitamin D in preventive medicine: are we ignoring the evidence? Brit J Nutr 2003; 89: 552-72
30. Terrier B, Carrat F, Geri G, et al. Low 25-OH vitamin D serum levels correlate with severe fibrosis in HIV-HCV co-infected patients with chronic hepatitis. J Hepatol 2011 Feb 17; [Epub ahead of print].
31. Hanwell HE, Vieth R, Cole DE, et al. Sun exposure questionnaire predicts circulating 25-hydroxyvitamin D concentrations in Caucasian hospital workers in southern Italy. J Steroid Biochem Mol Biol 2010; 121: 334-37.
32. van der Mei IA, Ponsonby AL, Engelsen O, et al. The high prevalence of vitamin D insufficiency across Australian populations is only partly explained by season and latitude. Environ Health Perspect 2007; 115: 1132-39.
33. Martín-Carbonero L, Benhamou Y, Puoti M, et al. Incidence and predictors of severe liver fibrosis in human immunodeficiency virus-infected patients with chronic hepatitis C: a European collaborative study. Clin Infect Dis 2004; 38: 128-33.
34. Sterling RK, Lissen E, Clumeck N et al. Development of a simple noninvasive index to predict significant fibrosis in patients with HIV/HCV coinfection. Hepatology 2006; 43: 1317-25.
35. Pittas AG, Chung M, Trikalinos T, et al. Systematic review: Vitamin D and cardiometabolic outcomes. Ann Inter Med 2010; 152: 307-14
36. Wang L, Manson JE, Song Y, Sesso HD. Systematic review: Vitamin D and calcium supplementation in prevention of cardiovascular events. Ann Inter Med 2010; 152: 315-23.