Cholesterol regulates HERG K+ channel activation by increasing phospholipase C β1 expression

Channels

Volumn 7, Issue 4, 2013, Pages 275-287

  Chun, Yoon Sun ^a   Oh, Hyun Geun ^a   Park, Myoung Kyu ^a   Cho, Hana ^a   Chung, Sungkwon ^a  

^a Sungkyunkwan University School of Medicine   (South Korea)

Author keywords

5 bisphosphate; Cholesterol; HERG; Long QT syndrome; Methyl cyclodextrin; Phosphatidylinositol 4; Phospholipase C

Indexed keywords

CHOLESTEROL; PHOSPHATIDYLINOSITOL 4,5 BISPHOSPHATE; PHOSPHOLIPASE C BETA1; PHOSPHOLIPASE C BETA3; POTASSIUM CHANNEL HERG; PHOSPHOLIPASE C BETA; PLCB1 PROTEIN, HUMAN;

ARTICLE; CELL MEMBRANE; CONTROLLED STUDY; DOWN REGULATION; HUMAN; HUMAN CELL; KINETICS; PROTEIN EXPRESSION; DEFICIENCY; DRUG EFFECTS; ELECTROPHYSIOLOGY; ENZYME ACTIVATION; GENE EXPRESSION REGULATION; GENETICS; HEK293 CELL LINE; METABOLISM;

CELL MEMBRANE; CHOLESTEROL; DOWN-REGULATION; ELECTROPHYSIOLOGICAL PROCESSES; ENZYME ACTIVATION; ETHER-A-GO-GO POTASSIUM CHANNELS; GENE EXPRESSION REGULATION, ENZYMOLOGIC; HEK293 CELLS; HUMANS; KINETICS; PHOSPHATIDYLINOSITOL 4,5-DIPHOSPHATE; PHOSPHOLIPASE C BETA;

EID: 84885655855     PISSN: 19336950     EISSN: 19336969     Source Type: Journal    
DOI: 10.4161/chan.25122     Document Type: Article

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