Cholesterol modulates ion channels via down-regulation of phosphatidylinositol 4,5-bisphosphate

Journal of Neurochemistry

Volumn 112, Issue 5, 2010, Pages 1286-1294

  Chun, Yoon Sun ^a   Shin, Sora ^a   Kim, Yonjung ^a   Cho, Hana ^a   Park, Myoung Kyu ^a   Kim, Tae Wan ^b   Voronov, Sergey V ^b   Di Paolo, Gilbert ^b   Suh, Byung Chang ^c   Chung, Sungkwon ^a  

^a Sungkyunkwan University   (South Korea)

^b Och Spine at New York Presbyterian Hospitals   (United States)

^c UNIVERSITY OF WASHINGTON SCHOOL OF MEDICINE   (United States)

Author keywords

Cholesterol; Human Ether a go go related gene; Mg2+ inhibitory cation channel; Phosphatidylinositol 4,5 bisphosphate; Phospholipase C

Indexed keywords

CATION CHANNEL; CHOLESTEROL; ION CHANNEL; PHOSPHATIDYLINOSITOL 4,5 BISPHOSPHATE; PHOSPHOLIPASE C; POTASSIUM CHANNEL HERG; POTASSIUM CHANNEL KCNQ;

ARTICLE; CELL STRAIN HEK293; CELL VIABILITY; DOWN REGULATION; ELECTROPHYSIOLOGY; ENZYME ACTIVATION; ENZYME ASSAY; ENZYME INHIBITION; ENZYME LINKED IMMUNOSORBENT ASSAY; HUMAN; HUMAN CELL; HUMAN CELL CULTURE; MODULATION; PRIORITY JOURNAL; PROTEIN EXPRESSION; REGULATORY MECHANISM;

BIOPHYSICS; CALCIUM; CELL LINE, TRANSFORMED; CELL SURVIVAL; CHOLESTEROL; CHROMATOGRAPHY, THIN LAYER; DOWN-REGULATION; ELECTRIC STIMULATION; ENZYME-LINKED IMMUNOSORBENT ASSAY; ETHER-A-GO-GO POTASSIUM CHANNELS; GREEN FLUORESCENT PROTEINS; HUMANS; ION CHANNEL GATING; KCNQ POTASSIUM CHANNELS; MAGNESIUM; MEMBRANE POTENTIALS; PATCH-CLAMP TECHNIQUES; PHOSPHATIDYLINOSITOL PHOSPHATES; TIME FACTORS; TRANSFECTION; TYPE C PHOSPHOLIPASES;

EID: 75949111029     PISSN: 00223042     EISSN: 14714159     Source Type: Journal    
DOI: 10.1111/j.1471-4159.2009.06545.x     Document Type: Article

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