-
1
-
-
0027932577
-
Multilevel therapeutic targeting by topoisomerase inhibitors
-
Smith PJ, Soues S. Multilevel therapeutic targeting by topoisomerase inhibitors. Br. J. Cancer 70, S47-S51 (1994 (Pubitemid 24275539)
-
(1994)
British Journal of Cancer
, vol.70
, Issue.SUPPL. 23
-
-
Smith, P.J.1
Soues, S.2
-
2
-
-
33646681444
-
HER2 and responsiveness of breast cancer to adjuvant chemotherapy
-
DOI 10.1056/NEJMoa054504
-
Pritchard KI, Shepherd LE, O'Malley FP et al. HER2 and responsiveness of breast cancer to adjuvant chemotherapy. N. Engl. J. Med. 354(20), 2103-2111 (2006 (Pubitemid 43736610)
-
(2006)
New England Journal of Medicine
, vol.354
, Issue.20
, pp. 2103-2111
-
-
Pritchard, K.I.1
Shepherd, L.E.2
O'Malley, F.P.3
Andrulis, I.L.4
Tu, D.5
Bramwell, V.H.6
Levine, M.N.7
-
3
-
-
0003298825
-
Her2 expression and anthracyclines effect: Results from the naples gun3 randomised trial
-
Abstract
-
De Laurentiis M, Caputo F, Massarelli E et al. HER2 expression and anthracyclines effect: results from the Naples GUN3 randomised trial. Proc. Am. Soc. Clin. Oncol. 20, Abstract 133 (2001
-
(2001)
Proc. Am. Soc. Clin. Oncol
, vol.20
, Issue.133
-
-
De Laurentiis, M.1
Caputo, F.2
Massarelli, E.3
-
4
-
-
0032538040
-
ErbB-2 and response to doxorubicin in patients with axillary lymph node- positive, hormone receptor-negative breast cancer
-
Paik S, Bryant J, Park C et al. ErbB-2 and response to doxorubicin in patients with axillary lymph node-positive, hormone receptor-negative breast cancer. J. Natl Cancer Inst. 90(18), 1361-1370 (1998 (Pubitemid 28439960)
-
(1998)
Journal of the National Cancer Institute
, vol.90
, Issue.18
, pp. 1361-1370
-
-
Paik, S.1
Bryant, J.2
Park, C.3
Fisher, B.4
Tan-Chiu, E.5
Hyams, D.6
Fisher, E.R.7
Lippman, M.E.8
Wickerham, D.L.9
Wolmark, N.10
-
5
-
-
0036091354
-
HER-2 amplification and topoisomerase IIα gene aberrations as predictive markers in node-positive breast cancer patients randomly treated either with an anthracycline-based therapy or with cyclophosphamide, methotrexate, and 5-fluorouracil
-
Di Leo A, Gancberg D, Larsimont D. HER-2 amplification and topoisomerase IIa gene aberrations as predictive markers in node-positive breast cancer patients randomly treated either with an anthracycline-based therapy or with cyclophosphamide, methotrexate, and 5-fluorouracil. Clin. Cancer Res. 8(5), 1107-1116 (2002 (Pubitemid 34517647)
-
(2002)
Clinical Cancer Research
, vol.8
, Issue.5
, pp. 1107-1116
-
-
Di Leo, A.1
Gancberg, D.2
Larsimont, D.3
Tanner, M.4
Jarvinen, T.5
Rouas, G.6
Dolci, S.7
Leroy, J.-Y.8
Paesmans, M.9
Isola, J.10
Piccart, M.J.11
-
6
-
-
32944475493
-
Retrospective analysis of topoisomerase IIa amplifications and deletions as predictive markers in primary breast cancer patients randomly assigned to cyclophosphamide, methotrexate, and fluorouracil or cyclophosphamide, epirubicin, and fluorouracil: Danish Breast Cancer Cooperative Group
-
DOI 10.1200/JCO.2005.11.007
-
Knoop AS, Knudsen H, Balslev E et al. Retrospective analysis of topoisomerase IIa amplifications and deletions as predictive markers in primary breast cancer patients randomly assigned to cyclophosphamide, methotrexate, and fluorouracil or cyclophosphamide, epirubicin, and fluorouracil: Danish Breast Cancer Cooperative Group. J. Clin. Oncol. 23(30), 7483-7490 (2005 (Pubitemid 46291811)
-
(2005)
Journal of Clinical Oncology
, vol.23
, Issue.30
, pp. 7483-7490
-
-
Knoop, A.S.1
Knudsen, H.2
Balslev, E.3
Rasmussen, B.B.4
Overgaard, J.5
Nielsen, K.V.6
Schonau, A.7
Gunnarsdottir, K.8
Olsen, K.E.9
Mouridsen, H.10
Ejlertsen, B.11
-
7
-
-
0037317929
-
HER2 overexpression and doxorubicin in adjuvant chemotherapy for resectable breast cancer
-
DOI 10.1200/JCO.2003.04.021
-
Moliterni A, Ménard S, Valagussa P et al. HER2 overexpression and doxorubicin in adjuvant chemotherapy for resectable breast cancer. J. Clin. Oncol. 21(3), 458-462 (2003 (Pubitemid 46606475)
-
(2003)
Journal of Clinical Oncology
, vol.21
, Issue.3
, pp. 458-462
-
-
Moliterni, A.1
Menard, S.2
Valagussa, P.3
Biganzoli, E.4
Boracchi, P.5
Balsari, A.6
Casalini, P.7
Tomasic, G.8
Marubini, E.9
Pilotti, S.10
Bonadonna, G.11
-
8
-
-
0034694659
-
HER2 and choice of adjuvant chemotherapy for invasive breast cancer: National surgical adjuvant breast and bowel project protocol B-15
-
Paik S, Bryant J, Tan-Chiu E et al. HER2 and choice of adjuvant chemotherapy for invasive breast cancer: National Surgical Adjuvant Breast and Bowel Project Protocol B-15. J. Natl Cancer Inst. 92(24), 1991-1998 (2000 (Pubitemid 32045895)
-
(2000)
Journal of the National Cancer Institute
, vol.92
, Issue.24
, pp. 1991-1998
-
-
Paik, S.1
Bryant, J.2
Tan-Chiu, E.3
Yothers, G.4
Park, C.5
Wickerham, D.L.6
Wolmark, N.7
-
9
-
-
38049103907
-
HER2 status and efficacy of adjuvant anthracyclines in early breast cancer: A pooled analysis of randomized trials
-
DOI 10.1093/jnci/djm252
-
Gennari A, Sormani MP, Pronzato P et al. HER2 status and efficacy of adjuvant anthracyclines in early breast cancer: a pooled analysis of randomized trials. J. Natl Cancer Inst. 100(1), 14-20 (2008). Demonstrates the additional benefit from inclusion of anthracyclines in adjuvant therapy in HER2-positive patients only. (Pubitemid 351767337)
-
(2008)
Journal of the National Cancer Institute
, vol.100
, Issue.1
, pp. 14-20
-
-
Gennari, A.1
Sormani, M.P.2
Pronzato, P.3
Puntoni, M.4
Colozza, M.5
Pfeffer, U.6
Bruzzi, P.7
-
10
-
-
43149115407
-
-
Reports that anthracycline therapy may have greater benefit in HER2-positive tumors
-
Dhesy-Thind B, Pritchard KI, Messersmith H, O'Malley F, Elavathil L, Trudeau M. HER2/neu in systemic therapy for women with breast cancer: a systematic review. Breast Cancer Res. Treat. 109(2), 209-229 (2008
-
(2008)
Dhesy-Thind B, Pritchard KI, Messersmith H, O'Malley F, Elavathil L, Trudeau M. HER2/neu in systemic therapy for women with breast cancer: A systematic review. Breast Cancer Res. Treat
, vol.109
, Issue.2
, pp. 209-229
-
-
-
11
-
-
77949895996
-
Her2, top2a, and timp-1 and responsiveness to adjuvant anthracycline-containing chemotherapy in high-risk breast cancer patients
-
Ejlertsen B, Jensen MB, Nielsen KV et al. HER2, TOP2A, and TIMP-1 and responsiveness to adjuvant anthracycline-containing chemotherapy in high-risk breast cancer patients. J. Clin. Oncol. 28(6), 984-990 (2010
-
(2010)
J. Clin. Oncol
, vol.28
, Issue.6
, pp. 984-990
-
-
Ejlertsen, B.1
Jensen, M.B.2
Nielsen, K.V.3
-
12
-
-
58149334773
-
A stroma-related gene signature predicts resistance to neoadjuvant chemotherapy in breast cancer
-
This stromal-based signature is predictive of anthracycline benefit. These pivotal data highlight the importance of the tumor microenvironment and reveals the interaction between the stroma and chemotherapy
-
Farmer P, Bonnefoi H, Anderle P et al. A stroma-related gene signature predicts resistance to neoadjuvant chemotherapy in breast cancer. Nat. Med. 15(1), 68-74 (2009
-
(2009)
Nat. Med
, vol.15
, Issue.1
, pp. 68-74
-
-
Farmer, P.1
Bonnefoi, H.2
Anderle, P.3
-
13
-
-
47949130625
-
Topoisomerase levels determine chemotherapy response in vitro and in vivo
-
Preclinical demonstration of TOP2A levels determining response to doxorubicin, with TOP2A suppression causing resistance
-
Burgess DJ, Doles J, Zender L et al. Topoisomerase levels determine chemotherapy response in vitro and in vivo. Proc. Natl Acad. Sci. USA 105(26), 9053-9058 (2008
-
(2008)
Proc. Natl Acad. Sci. USA
, vol.105
, Issue.26
, pp. 9053-9058
-
-
Burgess, D.J.1
Doles, J.2
Zender, L.3
-
14
-
-
65549158566
-
Topoisomerase iia and responsiveness of breast cancer to adjuvant chemotherapy
-
O'Malley FP, Chia S, Tu D et al. Topoisomerase IIa and responsiveness of breast cancer to adjuvant chemotherapy. J. Natl Cancer Inst. 101(9), 644-650 (2009
-
(2009)
J. Natl Cancer Inst
, vol.101
, Issue.9
, pp. 644-650
-
-
O'Malley, F.P.1
Chia, S.2
Tu, D.3
-
15
-
-
33744969590
-
Topoisomerase IIα gene amplification predicts favorable treatment response to tailored and dose-escalated anthracycline-based adjuvant chemotherapy in HER-2/neu-amplified breast cancer: Scandinavian Breast Group trial 9401
-
DOI 10.1200/JCO.2005.02.9264
-
Tanner M, Isola J, Wiklund T et al. Topoisomerase IIa gene amplification predicts favorable treatment response to tailored and dose-escalated anthracycline-based adjuvant chemotherapy in HER-2/neu-amplified breast cancer: Scandinavian Breast Group Trial 9401. J. Clin. Oncol. 24(16), 2428-2436 (2006 (Pubitemid 46630618)
-
(2006)
Journal of Clinical Oncology
, vol.24
, Issue.16
, pp. 2428-2436
-
-
Tanner, M.1
Isola, J.2
Wiklund, T.3
Erikstein, B.4
Kellokumpu-Lehtinen, P.5
Malmstrom, P.6
Wilking, N.7
Nilsson, J.8
Bergh, J.9
-
16
-
-
79955008762
-
Multifactorial approach to predicting resistance to anthracyclines
-
First prospective neoadjuvant clinical trial to assess TOP2A as a predictor of sensitivity to anthracyclines
-
Desmedt C, Di Leo A, de Azambuja E et al. Multifactorial approach to predicting resistance to anthracyclines. J. Clin. Oncol. 29(12), 1578-1586 (2011
-
(2011)
J. Clin. Oncol
, vol.29
, Issue.12
, pp. 1578-1586
-
-
Desmedt, C.1
Di Leo, A.2
De Azambuja, E.3
-
17
-
-
77955771686
-
Cef is superior to cmf for tumours with top2a aberrations: A subpopulation treatment effect pattern plot (stepp) analysis on danish breast cancer cooperative group study 89d
-
Gunnarsdóttir KA, Jensen MB, Zahrieh D et al. CEF is superior to CMF for tumours with TOP2A aberrations: a Subpopulation Treatment Effect Pattern Plot (STEPP) (stepp) analysis on danish breast cancer cooperative group study 89d Breast Cancer Res. Treat 2010 1231 163-169
-
(2010)
Breast Cancer Res. Treat
, vol.1231
, pp. 163-169
-
-
Gunnarsdóttir, K.A.1
Jensen, M.B.2
Zahrieh, D.3
-
18
-
-
81255129146
-
Her2 and top2a as predictive markers for anthracycline-containing chemotherapy regimens as adjuvant treatment of breast cancer: A meta-analysis of individual patient data
-
Findings from this large meta-analysis of five adjuvant trials do not support the restriction of anthracycline use to patients with HER2-amplified or TOP2A-aberrated tumors
-
Di Leo A, Desmedt C, Bartlett JM et al. HER2 and TOP2A as predictive markers for anthracycline-containing chemotherapy regimens as adjuvant treatment of breast cancer: a meta-analysis of individual patient data. Lancet Oncol. 12(12), 1134-1142 (2011). Findings from this large meta-analysis of five adjuvant trials do not support the restriction of anthracycline use to patients with HER2-amplified or TOP2A-aberrated tumors.
-
(2011)
Lancet Oncol
, vol.12
, Issue.12
, pp. 1134-1142
-
-
Di Leo, A.1
Desmedt, C.2
Bartlett, J.M.3
-
19
-
-
51349088017
-
Biological processes associated with breast cancer clinical outcome depend on the molecular subtypes
-
Desmedt C, Haibe-Kains B, Wirapati P et al. Biological processes associated with breast cancer clinical outcome depend on the molecular subtypes. Clin. Cancer Res. 14(16), 5158-5165 (2008
-
(2008)
Clin. Cancer Res
, vol.14
, Issue.16
, pp. 5158-5165
-
-
Desmedt, C.1
Haibe-Kains, B.2
Wirapati, P.3
-
20
-
-
54849441046
-
Type 1 receptor tyrosine kinase profiles identify patients with enhanced benefit from anthracyclines in the br9601 adjuvant breast cancer chemotherapy trial
-
Bartlett JM, Munro A, Cameron DA, Thomas J, Prescott R, Twelves CJ. Type 1 receptor tyrosine kinase profiles identify patients with enhanced benefit from anthracyclines in the BR9601 adjuvant breast cancer chemotherapy trial. J. Clin. Oncol. 26(31), 5027-5035 (2008
-
(2008)
J. Clin. Oncol
, vol.26
, Issue.31
, pp. 5027-5035
-
-
Bartlett, J.M.1
Munro, A.2
Cameron, D.A.3
Thomas, J.4
Prescott, R.5
Twelves, C.J.6
-
21
-
-
79959705252
-
Topoisomerase iia protein and responsiveness of breast cancer to adjuvant chemotherapy with cef compared to cmf in the ncic ctg randomized ma.5 adjuvant trial
-
O'Malley FP, Chia S, Tu D et al. Topoisomerase IIa protein and responsiveness of breast cancer to adjuvant chemotherapy with CEF compared to CMF in the NCIC CTG randomized MA.5 adjuvant trial. Breast Cancer Res. Treat. 128(2), 401-409 (2011
-
(2011)
Breast Cancer Res. Treat
, vol.128
, Issue.2
, pp. 401-409
-
-
O'Malley, F.P.1
Chia, S.2
Tu, D.3
-
22
-
-
7444252789
-
Topoisomerase-IIα expression as a predictive marker in a population of advanced breast cancer patients randomly treated either with single-agent doxorubicin or single-agent docetaxel
-
Durbecq V, Paesmans M, Cardoso F et al. Topoisomerase-IIa expression as a predictive marker in a population of advanced breast cancer patients randomly treated either with single-agent doxorubicin or single-agent docetaxel. Mol. Cancer Ther. 3(10), 1207-1214 (2004 (Pubitemid 39440165)
-
(2004)
Molecular Cancer Therapeutics
, vol.3
, Issue.10
, pp. 1207-1214
-
-
Durbecq, V.1
Paesmans, M.2
Cardoso, F.3
Desmedt, C.4
Di Leo, A.5
Chan, S.6
Friedrichs, K.7
Pinter, T.8
Van Belle, S.9
Murray, E.10
Bodrogi, I.11
Walpole, E.12
Lesperance, B.13
Korec, S.14
Crown, J.15
Simmonds, P.16
Perren, J.T.J.17
Leroy, J.-Y.18
Rouas, G.19
Sotiriou, C.20
Piccart, M.21
Larsimont, D.22
more..
-
23
-
-
65349120206
-
Doxorubicin and cyclophosphamide followed by weekly docetaxel as neoadjuvant treatment of early breast cancer: Analysis of biological markers in a geicam phase ii study
-
Gestevez L, Fortes JL, Adrover E et al. Doxorubicin and cyclophosphamide followed by weekly docetaxel as neoadjuvant treatment of early breast cancer: analysis of biological markers in a GEICAM Phase II study. Clin. Transl. Oncol. 11(1), 54-59 (2009
-
(2009)
Clin. Transl. Oncol
, vol.11
, Issue.1
, pp. 54-59
-
-
Gestevez, L.1
Fortes, J.L.2
Adrover, E.3
-
24
-
-
27644452196
-
C-erbb2 and topoisomerase iia protein expression independently predict poor survival in primary human breast cancer: A retrospective study
-
Fritz P, Cabrera CM, Dippon J et al. c-erbB2 and topoisomerase IIa protein expression independently predict poor survival in primary human breast cancer: a retrospective study. Breast Cancer Res. 7(3), R374-R384 (2005
-
(2005)
Breast Cancer Res
, vol.7
, Issue.3
-
-
Fritz, P.1
Cabrera, C.M.2
Dippon, J.3
-
25
-
-
16644362006
-
Correlation between topoisomerase-iia gene amplification and protein expression in her-2 amplified breast cancer
-
Durbecq V, Desmedt C, Paesmans M et al. Correlation between topoisomerase-IIa gene amplification and protein expression in HER-2 amplified breast cancer. Int. J. Oncol. 25(5), 1473-1479 (2004
-
(2004)
Int. J. Oncol
, vol.25
, Issue.5
, pp. 1473-1479
-
-
Durbecq, V.1
Desmedt, C.2
Paesmans, M.3
-
26
-
-
1542343905
-
Amplication of the TOP2A Gene Does Not Predict High Levels of Topoisomerase II Alpha Protein in Human Breast Tumor Samples
-
DOI 10.1002/gcc.20008
-
Mueller RE, Parkes RK, Andrulis I, O'Malley FP. Amplification of the TOP2A gene does not predict high levels of topoisomerase IIa protein in human breast tumor samples. Genes Chromosome Cancer 39(4), 288-297 (2004 (Pubitemid 38326310)
-
(2004)
Genes Chromosomes and Cancer
, vol.39
, Issue.4
, pp. 288-297
-
-
Mueller, R.E.1
Parkes, R.K.2
Andrulis, I.3
O'Malley, F.P.4
-
27
-
-
13844281018
-
Identification and validation of prognostic markers in breast cancer with the complementary use of array-CGH and tissue microarrays
-
DOI 10.1002/path.1694
-
Callagy G, Pharoah P, Chin SF et al. Identification and validation of prognostic markers in breast cancer with the complementary use of array-CGH and tissue microarrays. J. Pathol. 205(3), 388-396 (2005 (Pubitemid 40253928)
-
(2005)
Journal of Pathology
, vol.205
, Issue.3
, pp. 388-396
-
-
Callagy, G.1
Pharoah, P.2
Chin, S.-F.3
Sangan, T.4
Daigo, Y.5
Jackson, L.6
Caldas, C.7
-
28
-
-
77951019861
-
Erbb2 and top2a in breast cancer: A comprehensive analysis of gene amplification, rna levels, and protein expression and their influence on prognosis and prediction
-
Brase JC, Schmidt M, Fischbach T et al. ERBB2 and TOP2A in breast cancer: a comprehensive analysis of gene amplification, RNA levels, and protein expression and their influence on prognosis and prediction. Clin. Cancer Res. 16(8), 2391-2401 (2010).
-
(2010)
Clin. Cancer Res
, vol.16
, Issue.8
, pp. 2391-2401
-
-
Brase, J.C.1
Schmidt, M.2
Fischbach, T.3
-
29
-
-
56949083950
-
Topoisomerase iia as a marker predicting anthracyclines' activity in early breast cancer patients: Ready for the primetime?
-
Di Leo A, Biganzoli L, Claudino W, Licitra S, Pestrin M, Larsimont D. Topoisomerase IIa as a marker predicting anthracyclines' activity in early breast cancer patients: ready for the primetime? Eur. J. Cancer 44(18), 2791-2798 (2008
-
(2008)
Eur. J. Cancer
, vol.44
, Issue.18
, pp. 2791-2798
-
-
Di Leo, A.1
Biganzoli, L.2
Claudino, W.3
Licitra, S.4
Pestrin, M.5
Larsimont, D.6
-
30
-
-
0027746098
-
Growth factors. Clinical implications in breast cancer
-
Klijn JG, Berns PM, Bontenbal M, Foekens JA. Growth factors. Clinical implications in breast cancer. Ann. N.Y. Acad. Sci. 698, 85-101 (1993 (Pubitemid 24027627)
-
(1993)
Annals of the New York Academy of Sciences
, vol.698
, pp. 85-101
-
-
Klijn, J.G.M.1
Berns, P.M.J.2
Bontenbal, M.3
Foekens, J.A.4
-
31
-
-
2942521162
-
Proliferation markers predictive of the pathological response and disease outcome of patients with breast carcinomas treated by anthracycline-based preoperative chemotherapy
-
DOI 10.1016/j.ejca.2004.03.014, PII S0959804904002448
-
Vincent-Salomon A, Rousseau A, Jouve M et al. Proliferation markers predictive of the pathological response and disease outcome of patients with breast carcinomas treated by anthracycline-based preoperative chemotherapy. Eur. J. Cancer 40(10), 1502-1508 (2004 (Pubitemid 38757737)
-
(2004)
European Journal of Cancer
, vol.40
, Issue.10
, pp. 1502-1508
-
-
Vincent-Salomon, A.1
Rousseau, A.2
Jouve, M.3
Beuzeboc, P.4
Sigal-Zafrani, B.5
Freneaux, P.6
Rosty, C.7
Nos, C.8
Campana, F.9
Klijanienko, J.10
Al Ghuzlan, A.11
Sastre-Garau, X.12
-
32
-
-
77349118709
-
Predictive markers of anthracycline benefit: A prospectively planned analysis of the uk national epirubicin adjuvant trial (neatbr9601
-
Important results that conflict with many other trials and do not favor HER2, TOP2A or Ki67 as predictive tools for anthracycline use
-
Bartlett JM, Munro AF, Dunn JA et al. Predictive markers of anthracycline benefit: a prospectively planned analysis of the UK National Epirubicin Adjuvant Trial (NEAT/BR9601). Lancet Oncol. 11(3), 266-274 (2010). Important results that conflict with many other trials and do not favor HER2, TOP2A or Ki67 as predictive tools for anthracycline use.
-
(2010)
Lancet Oncol
, vol.11
, Issue.3
, pp. 266-274
-
-
Bartlett, J.M.1
Munro, A.F.2
Dunn, J.A.3
-
33
-
-
0034667463
-
Changes in subcellular distribution of topoisomerase iia correlate with etoposide resistance in multicell spheroid and xenograft tumours
-
Oloumi A, MacPhail SH, Johnston PJ, Banáth JP, Olive PL. Changes in subcellular distribution of topoisomerase IIa correlate with etoposide resistance in multicell spheroid and xenograft tumours. Cancer Res. 60(20), 5747-5753 (2000
-
(2000)
Cancer Res
, vol.60
, Issue.20
, pp. 5747-5753
-
-
Oloumi, A.1
MacPhail, S.H.2
Johnston, P.J.3
Banáth, J.P.4
Olive, P.L.5
-
34
-
-
0033865826
-
Ectopic expression of human topoisomerase iia fragments and etoposide resistance in mammalian cells
-
Ernst AI, Soltermann A, Sigrist JA, Widmer L, Gasser SM, Stahel RA. Ectopic expression of human topoisomerase IIa fragments and etoposide resistance in mammalian cells. Int. J. Cancer 88(1), 99-107 (2000
-
(2000)
Int. J. Cancer
, vol.88
, Issue.1
, pp. 99-107
-
-
Ernst, A.I.1
Soltermann, A.2
Sigrist, J.A.3
Widmer, L.4
Gasser, S.M.5
Stahel, R.A.6
-
35
-
-
1842829000
-
The cytoplasmic trafficking of DNA topoisomerase IIα correlates with etoposide resistance in human myeloma cells
-
DOI 10.1016/j.yexcr.2004.01.012, PII S0014482704000412
-
Engel R, Valkov NI, Gump JL, Hazlehurst L, Dalton WS, Sullivan DM. The cytoplasmic trafficking of DNA topoisomerase IIa correlates with etoposide resistance in human myeloma cells. Exp. Cell Res. 295(2), 421-431 (2004 (Pubitemid 38490496)
-
(2004)
Experimental Cell Research
, vol.295
, Issue.2
, pp. 421-431
-
-
Engel, R.1
Valkov, N.I.2
Gump, J.L.3
Hazlehurst, L.4
Dalton, W.S.5
Sullivan, D.M.6
-
36
-
-
70149109172
-
Human multiple myeloma cells are sensitized to topoisomerase ii inhibitors by crm1 inhibition
-
Turner JG, Marchion DC, Dawson JL et al. Human multiple myeloma cells are sensitized to topoisomerase II inhibitors by CRM1 inhibition. Cancer Res. 69(17), 6899-6905 (2009
-
(2009)
Cancer Res
, vol.69
, Issue.17
, pp. 6899-6905
-
-
Turner, J.G.1
Marchion, D.C.2
Dawson, J.L.3
-
37
-
-
0036852721
-
Automated subcellular localization and quantification of protein expression in tissue microarrays
-
DOI 10.1038/nm791
-
Camp RL, Chung GG, Rimm DL. Automated subcellular localization and quantification of protein expression in tissue microarrays. Nat. Med. 8(11), 1323-1327 (2002 (Pubitemid 35373567)
-
(2002)
Nature Medicine
, vol.8
, Issue.11
, pp. 1323-1327
-
-
Camp, R.L.1
Chung, G.G.2
Rimm, D.L.3
-
38
-
-
55549143664
-
Aqua analysis of thymidylate synthase reveals localization to be a key prognostic biomarker in 2 large cohorts of colorectal carcinoma
-
Gustavson MD, Molinaro AM, Tedeschi G, Camp RL, Rimm DL. AQUA analysis of thymidylate synthase reveals localization to be a key prognostic biomarker in 2 large cohorts of colorectal carcinoma. Arch. Pathol. Lab Med. 132(11), 1746-1752 (2008
-
(2008)
Arch. Pathol. Lab Med
, vol.132
, Issue.11
, pp. 1746-1752
-
-
Gustavson, M.D.1
Molinaro, A.M.2
Tedeschi, G.3
Camp, R.L.4
Rimm, D.L.5
-
39
-
-
84864917378
-
Association between the nuclear to cytoplasmic ratio of p27 and the efficacy of adjuvant polychemotherapy in early breast cancer
-
Andre F, Conforti R, Moeder CB et al. Association between the nuclear to cytoplasmic ratio of p27 and the efficacy of adjuvant polychemotherapy in early breast cancer. Ann. Oncol. 23(8), 2059-2064 (2012
-
(2012)
Ann. Oncol
, vol.23
, Issue.8
, pp. 2059-2064
-
-
Andre, F.1
Conforti, R.2
Moeder, C.B.3
-
40
-
-
65649138059
-
Quantitative, fluorescence-based in situ assessment of protein expression
-
Moeder CB, Giltnane JM, Moulis SP, Rimm DL. Quantitative, fluorescence-based in situ assessment of protein expression. Methods Mol. Biol. 520, 163-175 (2009
-
(2009)
Methods Mol. Biol
, vol.520
, pp. 163-175
-
-
Moeder, C.B.1
Giltnane, J.M.2
Moulis, S.P.3
Rimm, D.L.4
-
41
-
-
34250352390
-
Quantitative analysis of estrogen receptor heterogeneity in breast cancer
-
DOI 10.1038/labinvest.3700543, PII 3700543
-
Chung GG, Zerkowski MP, Ghosh S, Camp RL, Rimm DL. Quantitative analysis of estrogen receptor heterogeneity in breast cancer. Lab. Invest. 87(7), 662-669 (2007 (Pubitemid 46920099)
-
(2007)
Laboratory Investigation
, vol.87
, Issue.7
, pp. 662-669
-
-
Chung, G.G.1
Zerkowski, M.P.2
Ghosh, S.3
Camp, R.L.4
Rimm, D.L.5
-
42
-
-
84856210186
-
Novel molecular markers of malignancy in histologically normal and benign breast
-
Nasir A, Chen DT, Gruidl M et al. Novel molecular markers of malignancy in histologically normal and benign breast. Patholog. Res. Int. 2011, 489064 (2011).
-
(2011)
Patholog. Res. Int
, vol.2011
, pp. 489064
-
-
Nasir, A.1
Chen, D.T.2
Gruidl, M.3
|