-
1
-
-
0025940263
-
Expression of activated rat neuoncogene is sufficient to induce experimental metastasis in 3T3 cells
-
Yu DH, Hung MC: Expression of activated rat neu oncogene is sufficient to induce experimental metastasis in 3T3 cells. Oncogene. 1991, 6: 1991-1996.
-
(1991)
Oncogene
, vol.6
, pp. 1991-1996
-
-
Yu, D.H.1
Hung, M.C.2
-
2
-
-
0036091354
-
HER-2 amplification and topoisomerase IIalpha gene aberrations as predictive markers in node-positive breast cancer patients randomly treated either with an anthracycline-based therapy or with cyclophosphamide, methotrexate, and 5-fluorouracil
-
Di Leo A, Gancberg D, Larsimont D, Tanner M, Jarvinen T, Rouas G, Dolci S, Leroy JY, Paesmans M, Isola J, Piccart MJ: HER-2 amplification and topoisomerase IIalpha gene aberrations as predictive markers in node-positive breast cancer patients randomly treated either with an anthracycline-based therapy or with cyclophosphamide, methotrexate, and 5-fluorouracil. Clin Cancer Res. 2002, 8: 1107-1116.
-
(2002)
Clin Cancer Res
, vol.8
, pp. 1107-1116
-
-
Di Leo, A.1
Gancberg, D.2
Larsimont, D.3
Tanner, M.4
Jarvinen, T.5
Rouas, G.6
Dolci, S.7
Leroy, J.Y.8
Paesmans, M.9
Isola, J.10
Piccart, M.J.11
-
3
-
-
0036554731
-
Amplification and overexpression of topoisomerase IIalpha predict response to anthracycline-based therapy in locally advanced breast cancer
-
Coon JS, Marcus E, Gupta-Burt S, Seelig S, Jacobson K, Chen S, Renta V, Fronda G, Preisler HD: Amplification and overexpression of topoisomerase IIalpha predict response to anthracycline-based therapy in locally advanced breast cancer. Clin Cancer Res. 2002, 8: 1061-1067.
-
(2002)
Clin Cancer Res
, vol.8
, pp. 1061-1067
-
-
Coon, J.S.1
Marcus, E.2
Gupta-Burt, S.3
Seelig, S.4
Jacobson, K.5
Chen, S.6
Renta, V.7
Fronda, G.8
Preisler, H.D.9
-
4
-
-
0037333625
-
Topoisomerase II-alpha (topoII) and HER2 amplification in breast cancers and response to preoperative doxorubicin chemotherapy
-
Park K, Kim J, Lim S, Han S: Topoisomerase II-alpha (topoII) and HER2 amplification in breast cancers and response to preoperative doxorubicin chemotherapy. Eur J Cancer. 2003, 39: 631-634. 10.1016/S0959-8049(02)00745-1.
-
(2003)
Eur J Cancer
, vol.39
, pp. 631-634
-
-
Park, K.1
Kim, J.2
Lim, S.3
Han, S.4
-
5
-
-
3843120055
-
Correlation between complete response to anthracycline-based chemotherapy and topoisomerase II-alpha gene amplification and protein overexpression in locally advanced/metastatic breast cancer
-
Cardoso F, Durbecq V, Larsimont D, Paesmans M, Leroy JY, Rouas G, Sotiriou C, Renard N, Richard V, Piccart MJ, et al: Correlation between complete response to anthracycline-based chemotherapy and topoisomerase II-alpha gene amplification and protein overexpression in locally advanced/metastatic breast cancer. Int J Oncol. 2004, 24: 201-209.
-
(2004)
Int J Oncol
, vol.24
, pp. 201-209
-
-
Cardoso, F.1
Durbecq, V.2
Larsimont, D.3
Paesmans, M.4
Leroy, J.Y.5
Rouas, G.6
Sotiriou, C.7
Renard, N.8
Richard, V.9
Piccart, M.J.10
-
6
-
-
0141614011
-
Topoisomerase II alpha as a marker predicting the efficacy of anthracyclines in breast cancer: are we at the end of the beginning
-
Di Leo A, Isola J: Topoisomerase II alpha as a marker predicting the efficacy of anthracyclines in breast cancer: are we at the end of the beginning?. Clin Breast Cancer. 2003, 4: 179-186.
-
(2003)
Clin Breast Cancer
, vol.4
, pp. 179-186
-
-
Di Leo, A.1
Isola, J.2
-
7
-
-
0022588291
-
p185, a product of the neu proto-oncogene, is a receptorlike protein associated with tyrosine kinase activity
-
Stern DF, Heffernan PA, Weinberg RA: p185, a product of the neu proto-oncogene, is a receptorlike protein associated with tyrosine kinase activity. Mol Cell Biol. 1986, 6: 1729-1740.
-
(1986)
Mol Cell Biol
, vol.6
, pp. 1729-1740
-
-
Stern, D.F.1
Heffernan, P.A.2
Weinberg, R.A.3
-
8
-
-
0035496541
-
The role of c-erbB-2/HER2/neu in breast cancer progression and metastasis
-
Eccles SA: The role of c-erbB-2/HER2/neu in breast cancer progression and metastasis. J Mammary Gland Biol Neoplasia. 2001, 6: 393-406. 10.1023/A:1014730829872.
-
(2001)
J Mammary Gland Biol Neoplasia
, vol.6
, pp. 393-406
-
-
Eccles, S.A.1
-
9
-
-
0042208398
-
The Her-2/neu gene and protein in breast cancer 2003: biomarker and target of therapy
-
Ross JS, Fletcher JA, Linette GP, Stec J, Clark E, Ayers M, Symmans WF, Pusztai L, Bloom KJ: The Her-2/neu gene and protein in breast cancer 2003: biomarker and target of therapy. Oncologist. 2003, 8: 307-325. 10.1634/theoncologist.8-4-307.
-
(2003)
Oncologist
, vol.8
, pp. 307-325
-
-
Ross, J.S.1
Fletcher, J.A.2
Linette, G.P.3
Stec, J.4
Clark, E.5
Ayers, M.6
Symmans, W.F.7
Pusztai, L.8
Bloom, K.J.9
-
10
-
-
0036085460
-
Cellular roles of DNA topoisomerases: a molecular perspective
-
Wang JC: Cellular roles of DNA topoisomerases: a molecular perspective. Nat Rev Mol Cell Biol. 2002, 3: 430-440. 10.1038/nrm831.
-
(2002)
Nat Rev Mol Cell Biol
, vol.3
, pp. 430-440
-
-
Wang, J.C.1
-
11
-
-
0042630960
-
HER-2/neu and topoisomerase IIalpha - simultaneous drug targets in cancer
-
Jarvinen TA, Liu ET: HER-2/neu and topoisomerase IIalpha - simultaneous drug targets in cancer. Comb Chem High Throughput Screen. 2003, 6: 455-470.
-
(2003)
Comb Chem High Throughput Screen
, vol.6
, pp. 455-470
-
-
Jarvinen, T.A.1
Liu, E.T.2
-
12
-
-
0027168686
-
Co-amplification of erbB2, topoisomerase II alpha and retinoic acid receptor alpha genes in breast cancer and allelic loss at topoisomerase I on chromosome 20
-
Keith WN, Douglas F, Wishart GC, McCallum HM, George WD, Kaye SB, Brown R: Co-amplification of erbB2, topoisomerase II alpha and retinoic acid receptor alpha genes in breast cancer and allelic loss at topoisomerase I on chromosome 20. Eur J Cancer. 1993, 29A: 1469-1475. 10.1016/0959-8049(93)90022-8.
-
(1993)
Eur J Cancer
, vol.29A
, pp. 1469-1475
-
-
Keith, W.N.1
Douglas, F.2
Wishart, G.C.3
McCallum, H.M.4
George, W.D.5
Kaye, S.B.6
Brown, R.7
-
13
-
-
0028927502
-
Interphase cytogenetic analysis of erbB2 and topoII alpha co-amplification in invasive breast cancer and polysomy of chromosome 17 in ductal carcinoma in situ
-
Murphy DS, McHardy P, Coutts J, Mallon EA, George WD, Kaye SB, Brown R, Keith WN: Interphase cytogenetic analysis of erbB2 and topoII alpha co-amplification in invasive breast cancer and polysomy of chromosome 17 in ductal carcinoma in situ. Int J Cancer. 1995, 64: 18-26.
-
(1995)
Int J Cancer
, vol.64
, pp. 18-26
-
-
Murphy, D.S.1
McHardy, P.2
Coutts, J.3
Mallon, E.A.4
George, W.D.5
Kaye, S.B.6
Brown, R.7
Keith, W.N.8
-
14
-
-
0043145754
-
Characterization of topoisomerase II alpha gene amplification and deletion in breast cancer
-
Jarvinen TA, Tanner M, Barlund M, Borg A, Isola J: Characterization of topoisomerase II alpha gene amplification and deletion in breast cancer. Genes Chromosomes Cancer. 1999, 26: 142-150.
-
(1999)
Genes Chromosomes Cancer
, vol.26
, pp. 142-150
-
-
Jarvinen, T.A.1
Tanner, M.2
Barlund, M.3
Borg, A.4
Isola, J.5
-
15
-
-
0029665095
-
Expression of topoisomerase IIalpha is associated with rapid cell proliferation, aneuploidy, and c-erbB2 overexpression in breast cancer
-
Jarvinen TA, Kononen J, Pelto-Huikko M, Isola J: Expression of topoisomerase IIalpha is associated with rapid cell proliferation, aneuploidy, and c-erbB2 overexpression in breast cancer. Am J Pathol. 1996, 148: 2073-2082.
-
(1996)
Am J Pathol
, vol.148
, pp. 2073-2082
-
-
Jarvinen, T.A.1
Kononen, J.2
Pelto-Huikko, M.3
Isola, J.4
-
16
-
-
16644362006
-
Correlation between topoisomerase IIalpha gene amplification and protein expression in Her-2 amplified breast cancer
-
Durbecq V, Desmedt C, Paesmans M, Cardoso F, Di Leo A, Mano M, Rouas G, Leroy J-Y, Sotiriou C, Piccart M, et al: Correlation between topoisomerase IIalpha gene amplification and protein expression in Her-2 amplified breast cancer. Int J Oncol. 2004, 25: 1473-1479.
-
(2004)
Int J Oncol
, vol.25
, pp. 1473-1479
-
-
Durbecq, V.1
Desmedt, C.2
Paesmans, M.3
Cardoso, F.4
Di Leo, A.5
Mano, M.6
Rouas, G.7
Leroy, J.-Y.8
Sotiriou, C.9
Piccart, M.10
-
17
-
-
0042838307
-
Breast cancer classification and prognosis based on gene expression profiles from a population-based study
-
Sotiriou C, Neo SY, McShane LM, Korn EL, Long PM, Jazaeri A, Martiat P, Fox SB, Harris AL, Liu ET: Breast cancer classification and prognosis based on gene expression profiles from a population-based study. Proc Natl Acad Sci USA. 2003, 100: 10393-10398. 10.1073/pnas.1732912100.
-
(2003)
Proc Natl Acad Sci USA
, vol.100
, pp. 10393-10398
-
-
Sotiriou, C.1
Neo, S.Y.2
McShane, L.M.3
Korn, E.L.4
Long, P.M.5
Jazaeri, A.6
Martiat, P.7
Fox, S.B.8
Harris, A.L.9
Liu, E.T.10
-
18
-
-
0035092216
-
Functional and regulatory characteristics of eukaryotic type II DNA topoisomerase
-
Bakshi RP, Galande S, Muniyappa K: Functional and regulatory characteristics of eukaryotic type II DNA topoisomerase. Crit Rev Biochem Mol Biol. 2001, 36: 1-37.
-
(2001)
Crit Rev Biochem Mol Biol
, vol.36
, pp. 1-37
-
-
Bakshi, R.P.1
Galande, S.2
Muniyappa, K.3
-
19
-
-
0020957656
-
Histological typing of breast tumors
-
The World Health Organization: Histological typing of breast tumors. Neoplasma. 1983, 30: 113-123.
-
(1983)
Neoplasma
, vol.30
, pp. 113-123
-
-
-
20
-
-
0025235360
-
Interpretation of the estrogen receptor content of breast cancer
-
Tuczek HV, Fritz P, Oeffinger B, Limbach HJ, Mischlinski A, Klein C, Wegner G: Interpretation of the estrogen receptor content of breast cancer. Geburtshilfe Frauenheilkd. 1990, 50: 314-318.
-
(1990)
Geburtshilfe Frauenheilkd
, vol.50
, pp. 314-318
-
-
Tuczek, H.V.1
Fritz, P.2
Oeffinger, B.3
Limbach, H.J.4
Mischlinski, A.5
Klein, C.6
Wegner, G.7
-
21
-
-
0030018766
-
Differential expression of the topoisomerase II alpha and beta genes in human breast cancers
-
Sandri MI, Hochhauser D, Ayton P, Camplejohn RC, Whitehouse R, Turley H, Gatter K, Hickson ID, Harris AL: Differential expression of the topoisomerase II alpha and beta genes in human breast cancers. Br J. 1996, 73: 1518-1524.
-
(1996)
Br J
, vol.73
, pp. 1518-1524
-
-
Sandri, M.I.1
Hochhauser, D.2
Ayton, P.3
Camplejohn, R.C.4
Whitehouse, R.5
Turley, H.6
Gatter, K.7
Hickson, I.D.8
Harris, A.L.9
-
22
-
-
0032189117
-
Treatment of breast cancer
-
Hortobagyi GN: Treatment of breast cancer. N Engl J Med. 1998, 339: 974-984. 10.1056/NEJM199810013391407.
-
(1998)
N Engl J Med
, vol.339
, pp. 974-984
-
-
Hortobagyi, G.N.1
-
23
-
-
0032816621
-
Prognostic significance of Ki-67 and topoisomerase IIalpha expression in infiltrating ductal carcinoma of the breast. A multivariate analysis of 863 cases
-
Rudolph P, MacGrogan G, Bonichon F, Frahm SO, de Mascarel I, Trojani M, Durand M, Avril A, Coindre JM, Parwaresch R: Prognostic significance of Ki-67 and topoisomerase IIalpha expression in infiltrating ductal carcinoma of the breast. A multivariate analysis of 863 cases. Breast Cancer Res Treat. 1999, 55: 61-71. 10.1023/A:1006159016703.
-
(1999)
Breast Cancer Res Treat
, vol.55
, pp. 61-71
-
-
Rudolph, P.1
MacGrogan, G.2
Bonichon, F.3
Frahm, S.O.4
de Mascarel, I.5
Trojani, M.6
Durand, M.7
Avril, A.8
Coindre, J.M.9
Parwaresch, R.10
-
24
-
-
0033870292
-
Amplification and deletion of topoisomerase IIalpha associate with ErbB-2 amplification and affect sensitivity to topoisomerase II inhibitor doxorubicin in breast cancer
-
Jarvinen TA, Tanner M, Rantanen V, Barlund M, Borg A, Grenman S, Isola J: Amplification and deletion of topoisomerase IIalpha associate with ErbB-2 amplification and affect sensitivity to topoisomerase II inhibitor doxorubicin in breast cancer. Am J Pathol. 2000, 156: 839-847.
-
(2000)
Am J Pathol
, vol.156
, pp. 839-847
-
-
Jarvinen, T.A.1
Tanner, M.2
Rantanen, V.3
Barlund, M.4
Borg, A.5
Grenman, S.6
Isola, J.7
-
25
-
-
0029852430
-
Transfection of human topoisomerase II alpha into etoposide-resistant cells: transient increase in sensitivity followed by down-regulation of the endogenous gene
-
Asano T, An T, Mayes J, Zwelling LA, Kleinerman ES: Transfection of human topoisomerase II alpha into etoposide-resistant cells: transient increase in sensitivity followed by down-regulation of the endogenous gene. Biochem J. 1996, 319: 307-313.
-
(1996)
Biochem J
, vol.319
, pp. 307-313
-
-
Asano, T.1
An, T.2
Mayes, J.3
Zwelling, L.A.4
Kleinerman, E.S.5
-
26
-
-
9144242764
-
Comparative value of tumour grade, hormonal receptors, Ki-67, HER-2 and topoisomerase II alpha status as predictive markers in breast cancer patients treated with neoadjuvant anthracycline-based chemotherapy
-
Petit T, Wilt M, Velten M, Millon R, Rodier JF, Borel C, Mors R, Haegele P, Eber M, Ghnassia JP: Comparative value of tumour grade, hormonal receptors, Ki-67, HER-2 and topoisomerase II alpha status as predictive markers in breast cancer patients treated with neoadjuvant anthracycline-based chemotherapy. Eur J Cancer. 2004, 40: 205-211. 10.1016/S0959-8049(03)00675-0.
-
(2004)
Eur J Cancer
, vol.40
, pp. 205-211
-
-
Petit, T.1
Wilt, M.2
Velten, M.3
Millon, R.4
Rodier, J.F.5
Borel, C.6
Mors, R.7
Haegele, P.8
Eber, M.9
Ghnassia, J.P.10
-
27
-
-
0034486459
-
DNA topoisomerase II-alpha immunoreactivity as a marker of tumor aggressiveness in invasive breast cancer
-
Nakopoulou L, Lazaris AC, Kavantzas N, Alexandrou P, Athanassiadou P, Keramopoulos A, Davaris P: DNA topoisomerase II-alpha immunoreactivity as a marker of tumor aggressiveness in invasive breast cancer. Pathobiology. 2000, 68: 137-143. 10.1159/000055914.
-
(2000)
Pathobiology
, vol.68
, pp. 137-143
-
-
Nakopoulou, L.1
Lazaris, A.C.2
Kavantzas, N.3
Alexandrou, P.4
Athanassiadou, P.5
Keramopoulos, A.6
Davaris, P.7
-
28
-
-
12444269092
-
Enforced cytokinesis without complete nuclear division in embryonic cells depleting the activity of DNA topoisomerase IIalpha
-
Akimitsu N, Adachi N, Hirai H, Hossain MS, Hamamoto H, Kobayashi M, Aratani Y, Koyama H, Sekimizu K: Enforced cytokinesis without complete nuclear division in embryonic cells depleting the activity of DNA topoisomerase IIalpha. Genes Cells. 2003, 8: 393-402. 10.1046/j.1365-2443.2003.00643.x.
-
(2003)
Genes Cells
, vol.8
, pp. 393-402
-
-
Akimitsu, N.1
Adachi, N.2
Hirai, H.3
Hossain, M.S.4
Hamamoto, H.5
Kobayashi, M.6
Aratani, Y.7
Koyama, H.8
Sekimizu, K.9
-
29
-
-
0038013811
-
Induction of apoptosis by depletion of DNA topoisomerase IIalpha in mammalian cells
-
Akimitsu N, Kamura K, Tone S, Sakaguchi A, Kikuchi A, Hamamoto H, Sekimizu K: Induction of apoptosis by depletion of DNA topoisomerase IIalpha in mammalian cells. Biochem Biophys Res Commun. 2003, 307: 301-307. 10.1016/S0006-291X(03)01169-0.
-
(2003)
Biochem Biophys Res Commun
, vol.307
, pp. 301-307
-
-
Akimitsu, N.1
Kamura, K.2
Tone, S.3
Sakaguchi, A.4
Kikuchi, A.5
Hamamoto, H.6
Sekimizu, K.7
-
30
-
-
0032532085
-
Induction of apoptosis by deregulated expression of DNA topoisomerase IIalpha
-
McPherson JP, Goldenberg GJ: Induction of apoptosis by deregulated expression of DNA topoisomerase IIalpha. Cancer Res. 1998, 58: 4519-4524.
-
(1998)
Cancer Res
, vol.58
, pp. 4519-4524
-
-
McPherson, J.P.1
Goldenberg, G.J.2
|