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Volumn 295, Issue 2, 2004, Pages 421-431

The cytoplasmic trafficking of DNA topoisomerase IIα correlates with etoposide resistance in human myeloma cells

Author keywords

BME; BrdU; Bromodeoxyuridine; DNA topoisomerase II ; Drug resistance; FBS; Fetal bovine serum; FITC; Fluorescein isothiocyanate; Leptomycin B; Multiple myeloma; Protein trafficking; Topo; Topoisomerase; TRITC; mercaptoethanol

Indexed keywords

ANTINEOPLASTIC AGENT; BROXURIDINE; CARMUSTINE; CISPLATIN; CYTARABINE; DNA TOPOISOMERASE; DNA TOPOISOMERASE 2ALPHA; DNA TOPOISOMERASE 2BETA; DOUBLE STRANDED DNA; ETOPOSIDE; GYRASE INHIBITOR; LEPTOMYCIN B; MITOXANTRONE; PACLITAXEL; TOPOTECAN; UNCLASSIFIED DRUG;

EID: 1842829000     PISSN: 00144827     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.yexcr.2004.01.012     Document Type: Article
Times cited : (31)

References (43)
  • 1
    • 0034923502 scopus 로고    scopus 로고
    • DNA topoisomerases: Structure, function, and mechanism
    • Champoux J.J. DNA topoisomerases: structure, function, and mechanism. Annu. Rev. Biochem. 70:2001;369-413.
    • (2001) Annu. Rev. Biochem. , vol.70 , pp. 369-413
    • Champoux, J.J.1
  • 2
    • 0036085460 scopus 로고    scopus 로고
    • Cellular roles of DNA topoisomerases: A molecular perspective
    • Wang J.C. Cellular roles of DNA topoisomerases: a molecular perspective. Nat. Rev., Mol. Cell Biol. 6:2002;430-440.
    • (2002) Nat. Rev., Mol. Cell Biol. , vol.6 , pp. 430-440
    • Wang, J.C.1
  • 3
    • 0030014783 scopus 로고    scopus 로고
    • DNA topoisomerases
    • Wang J.C. DNA topoisomerases. Annu. Rev. Biochem. 65:1996;635-692.
    • (1996) Annu. Rev. Biochem. , vol.65 , pp. 635-692
    • Wang, J.C.1
  • 4
    • 0032189942 scopus 로고    scopus 로고
    • Investigating the biological functions of DNA topoisomerases in eukaryotic cells
    • Nitiss J.L. Investigating the biological functions of DNA topoisomerases in eukaryotic cells. Biochim. Biophys. Acta. 1400:1998;63-81.
    • (1998) Biochim. Biophys. Acta , vol.1400 , pp. 63-81
    • Nitiss, J.L.1
  • 6
    • 0022896243 scopus 로고
    • Topoisomerase II: A specific marker for cell proliferation
    • Heck M.M., Earnshaw W.C. Topoisomerase II: a specific marker for cell proliferation. J. Cell Biol. 103:1986;2569-2581.
    • (1986) J. Cell Biol. , vol.103 , pp. 2569-2581
    • Heck, M.M.1    Earnshaw, W.C.2
  • 7
    • 0027251059 scopus 로고
    • Cell-cycle dependent phosphorylation and activity of Chinese hamster ovary topoisomerase II
    • Burden D.A., Goldsmith L.J., Sullivan D.M. Cell-cycle dependent phosphorylation and activity of Chinese hamster ovary topoisomerase II. Biochem. J. 293:1993;297-304.
    • (1993) Biochem. J. , vol.293 , pp. 297-304
    • Burden, D.A.1    Goldsmith, L.J.2    Sullivan, D.M.3
  • 8
    • 0026147704 scopus 로고
    • Proliferation and cell cycle-dependent differences in expression of the 170 kilodalton and 180 kilodalton forms of topoisomerase II in NIH-3T3 cells
    • Woessner R.D., Mattern M.R., Mirabelli C.K., Johnson R.K., Drake F.H. Proliferation and cell cycle-dependent differences in expression of the 170 kilodalton and 180 kilodalton forms of topoisomerase II in NIH-3T3 cells. Cell Growth Differ. 2:1991;209-214.
    • (1991) Cell Growth Differ. , vol.2 , pp. 209-214
    • Woessner, R.D.1    Mattern, M.R.2    Mirabelli, C.K.3    Johnson, R.K.4    Drake, F.H.5
  • 9
    • 0030887316 scopus 로고    scopus 로고
    • The distribution and expression of the two isoforms of DNA topoisomerase II in normal and neoplastic human tissues
    • Turley H., Comley M., Houlbrook S., Nozaki N., Kikuchi A., Hickson I.D., Gatter K., Harris A.L. The distribution and expression of the two isoforms of DNA topoisomerase II in normal and neoplastic human tissues. Br. J. Cancer. 75:1997;1340-1346.
    • (1997) Br. J. Cancer , vol.75 , pp. 1340-1346
    • Turley, H.1    Comley, M.2    Houlbrook, S.3    Nozaki, N.4    Kikuchi, A.5    Hickson, I.D.6    Gatter, K.7    Harris, A.L.8
  • 10
    • 0028878831 scopus 로고
    • Topoisomerase inhibitors: A review of their therapeutic potential in cancer
    • Sinha B.K. Topoisomerase inhibitors: a review of their therapeutic potential in cancer. Drugs. 49:1995;11-19.
    • (1995) Drugs , vol.49 , pp. 11-19
    • Sinha, B.K.1
  • 11
    • 0032190407 scopus 로고    scopus 로고
    • Clinical applications of anticancer drugs targeted to topoisomerase II
    • Hande K.R. Clinical applications of anticancer drugs targeted to topoisomerase II. Biochim. Biophys. Acta. 1400:1998;173-184.
    • (1998) Biochim. Biophys. Acta , vol.1400 , pp. 173-184
    • Hande, K.R.1
  • 12
    • 0001886735 scopus 로고    scopus 로고
    • Pharmacology and molecular mechanism of action or resistance of antineoplastic agents: Current status and future potential
    • R. Hoffman, E.J. Benz, S.J. Shattil, B. Furie, H.J. Cohen, L.E. Silberstein, & P. McGlave. New York, NY: Churchill Livingstone
    • Bhalla K., Gerson S., Grant S.S., Sullivan D.M. Pharmacology and molecular mechanism of action or resistance of antineoplastic agents: current status and future potential. Hoffman R., Benz E.J., Shattil S.J., Furie B., Cohen H.J., Silberstein L.E., McGlave P. Hematology: Basic Principles and Practice. 2000;885-938 Churchill Livingstone, New York, NY.
    • (2000) Hematology: Basic Principles and Practice , pp. 885-938
    • Bhalla, K.1    Gerson, S.2    Grant, S.S.3    Sullivan, D.M.4
  • 14
    • 0031452670 scopus 로고    scopus 로고
    • Drug resistance to DNA topoisomerase I and II inhibitors in human leukemia, lymphoma, and multiple myeloma
    • Valkov N.I., Sullivan D.M. Drug resistance to DNA topoisomerase I and II inhibitors in human leukemia, lymphoma, and multiple myeloma. Semin. Hematol. 34:1997;48-68.
    • (1997) Semin. Hematol. , vol.34 , pp. 48-68
    • Valkov, N.I.1    Sullivan, D.M.2
  • 15
    • 0032189251 scopus 로고    scopus 로고
    • Cellular resistance to topoisomerase-targeted drugs: From drug uptake to cell death
    • Larsen A.K., Skladanowski A. Cellular resistance to topoisomerase- targeted drugs: from drug uptake to cell death. Biochim. Biophys. Acta. 1400:1998;257-274.
    • (1998) Biochim. Biophys. Acta , vol.1400 , pp. 257-274
    • Larsen, A.K.1    Skladanowski, A.2
  • 16
    • 0031435837 scopus 로고    scopus 로고
    • Mechanisms of drug resistance in hematologic malignancies
    • Dalton W.S. Mechanisms of drug resistance in hematologic malignancies. Semin. Hematol. 34:1997;3-8.
    • (1997) Semin. Hematol. , vol.34 , pp. 3-8
    • Dalton, W.S.1
  • 17
  • 18
    • 0001744641 scopus 로고    scopus 로고
    • Multidrug resistance and pharmacological protection mediated by the breast cancer resistance protein (BCRP/ABCG2)
    • Allen J.D., Schinkel A.H. Multidrug resistance and pharmacological protection mediated by the breast cancer resistance protein (BCRP/ABCG2). Mol. Cancer Ther. 1:2002;427-434.
    • (2002) Mol. Cancer Ther. , vol.1 , pp. 427-434
    • Allen, J.D.1    Schinkel, A.H.2
  • 20
    • 0023275078 scopus 로고
    • Proliferation-dependent topoisomerase II content as a determinant of antineoplastic drug action in human, mouse, and Chinese hamster ovary cells
    • Sullivan D.M., Latham M.D., Ross W.E. Proliferation-dependent topoisomerase II content as a determinant of antineoplastic drug action in human, mouse, and Chinese hamster ovary cells. Cancer Res. 47:1987;3973-3979.
    • (1987) Cancer Res. , vol.47 , pp. 3973-3979
    • Sullivan, D.M.1    Latham, M.D.2    Ross, W.E.3
  • 21
    • 0030912109 scopus 로고    scopus 로고
    • Two COOH-terminal truncated cytoplasmic forms of topoisomerase IIα in a VP-16-selected lung cancer cell line result from partial gene deletion and alternative splicing
    • Yu Q., Mirski S.L., Sparks K.E., Cole S.C. Two COOH-terminal truncated cytoplasmic forms of topoisomerase IIα in a VP-16-selected lung cancer cell line result from partial gene deletion and alternative splicing. Biochemistry. 36:1997;5868-5877.
    • (1997) Biochemistry , vol.36 , pp. 5868-5877
    • Yu, Q.1    Mirski, S.L.2    Sparks, K.E.3    Cole, S.C.4
  • 22
    • 0002291316 scopus 로고    scopus 로고
    • Topoisomerase II inhibitors: The epipodophyllotoxins, m-AMSA, and the ellipticine derivatives
    • B.A. Chabner, & D.L. Longo. Philadelphia: Lippincott-Raven Publishers
    • Pommier Y., Fesen M.R., Goldwasser F. Topoisomerase II inhibitors: the epipodophyllotoxins, m-AMSA, and the ellipticine derivatives. Chabner B.A., Longo D.L. Cancer Chemotherapy and Biotherapy. 1996;435-461 Lippincott-Raven Publishers, Philadelphia.
    • (1996) Cancer Chemotherapy and Biotherapy , pp. 435-461
    • Pommier, Y.1    Fesen, M.R.2    Goldwasser, F.3
  • 23
    • 0034053994 scopus 로고    scopus 로고
    • Cell density-dependent VP-16 sensitivity of leukemic cells is accompanied by the translocation of topo IIα from the nucleus to the cytoplasm
    • Valkov N.I., Gump J.L., Engel R., Sullivan D.M. Cell density-dependent VP-16 sensitivity of leukemic cells is accompanied by the translocation of topo IIα from the nucleus to the cytoplasm. Br. J. Haematol. 108:2000;331-334.
    • (2000) Br. J. Haematol. , vol.108 , pp. 331-334
    • Valkov, N.I.1    Gump, J.L.2    Engel, R.3    Sullivan, D.M.4
  • 24
    • 0034667463 scopus 로고    scopus 로고
    • Changes in subcellular distribution of topoisomerase IIα correlate with etoposide resistance in multicell spheroids and xenograft tumors
    • Oloumi A., MacPhail S.H., Johnston P.J., Banáth J.P., Olive P.L. Changes in subcellular distribution of topoisomerase IIα correlate with etoposide resistance in multicell spheroids and xenograft tumors. Cancer Res. 60:2000;5747-5753.
    • (2000) Cancer Res. , vol.60 , pp. 5747-5753
    • Oloumi, A.1    MacPhail, S.H.2    Johnston, P.J.3    Banáth, J.P.4    Olive, P.L.5
  • 26
    • 0033865826 scopus 로고    scopus 로고
    • Ectopic expression of human topoisomerase IIα fragments and etoposide resistance in mammalian cells
    • Ernst A., Soltermann A., Sigrist J.A., Widmer L., Gasser S.M., Stahel R.A. Ectopic expression of human topoisomerase IIα fragments and etoposide resistance in mammalian cells. Int. J. Cancer. 88:2000;99-107.
    • (2000) Int. J. Cancer , vol.88 , pp. 99-107
    • Ernst, A.1    Soltermann, A.2    Sigrist, J.A.3    Widmer, L.4    Gasser, S.M.5    Stahel, R.A.6
  • 27
    • 0029072779 scopus 로고
    • Expression, domain structure, and enzymatic properties of an active recombinant human DNA topoisomerase IIβ
    • Austin C.A., Marsh K.L., Wasserman R.A., Wilmore E., Sayer P.J., Wang J.C., Fisher L.M. Expression, domain structure, and enzymatic properties of an active recombinant human DNA topoisomerase IIβ J. Biol. Chem. 270:1995;15739-15746.
    • (1995) J. Biol. Chem. , vol.270 , pp. 15739-15746
    • Austin, C.A.1    Marsh, K.L.2    Wasserman, R.A.3    Wilmore, E.4    Sayer, P.J.5    Wang, J.C.6    Fisher, L.M.7
  • 29
    • 0029072716 scopus 로고
    • Camptothecin induction of a time- and concentration-dependent decrease of topoisomerase I and its implication in camptothecin activity
    • Beidler D.R., Cheng Y.-C. Camptothecin induction of a time- and concentration-dependent decrease of topoisomerase I and its implication in camptothecin activity. Mol. Pharmacol. 47:1995;907-914.
    • (1995) Mol. Pharmacol. , vol.47 , pp. 907-914
    • Beidler, D.R.1    Cheng, Y.-C.2
  • 31
    • 0030933933 scopus 로고    scopus 로고
    • Altered formation of topotecan-stabilized topoisomerase I-DNA adducts in human leukemia cells
    • Kaufmann S.H., Svingen P.A., Gore S.T., Armstrong D.K., Cheng Y.C., Rowinsky E.K. Altered formation of topotecan-stabilized topoisomerase I-DNA adducts in human leukemia cells. Blood. 89:1997;2098-2104.
    • (1997) Blood , vol.89 , pp. 2098-2104
    • Kaufmann, S.H.1    Svingen, P.A.2    Gore, S.T.3    Armstrong, D.K.4    Cheng, Y.C.5    Rowinsky, E.K.6
  • 32
    • 0029045164 scopus 로고
    • The comet moment as a measurement of DNA damage in the comet assay
    • Kent C.R., Eady J.J., Ross G.M., Steel G.G. The comet moment as a measurement of DNA damage in the comet assay. Int. J. Radiat. Biol. 67:1995;655-660.
    • (1995) Int. J. Radiat. Biol. , vol.67 , pp. 655-660
    • Kent, C.R.1    Eady, J.J.2    Ross, G.M.3    Steel, G.G.4
  • 33
    • 0021875410 scopus 로고
    • DNA topoisomerase I and II activities during cell proliferation and the cell cycle in cultured mouse embryo fibroblast (C3H 10T/2) cells
    • Tricoli J.V., Sahai B.M., McCormick P.J., Jarlinski S.J., Bertram J.S., Kowalski D. DNA topoisomerase I and II activities during cell proliferation and the cell cycle in cultured mouse embryo fibroblast (C3H 10T/2) cells. Exp. Cell Res. 158:1985;1-14.
    • (1985) Exp. Cell Res. , vol.158 , pp. 1-14
    • Tricoli, J.V.1    Sahai, B.M.2    McCormick, P.J.3    Jarlinski, S.J.4    Bertram, J.S.5    Kowalski, D.6
  • 34
    • 0023927993 scopus 로고
    • Proliferation-dependent regulation of DNA topoisomerase II in cultured human cells
    • Hsiang Y.-H., Wu H.-Y., Liu L.F. Proliferation-dependent regulation of DNA topoisomerase II in cultured human cells. Cancer Res. 48:1988;230-3235.
    • (1988) Cancer Res. , vol.48 , pp. 230-3235
    • Hsiang, Y.-H.1    Wu, H.-Y.2    Liu, L.F.3
  • 35
    • 0022414531 scopus 로고
    • Leptomycins a and B, new antifungal antibiotics: III. Mode of action of leptomycin B on Schizosaccharomyces pombe
    • Hamamoto T., Gunji S., Tsuji H., Beppu T. Leptomycins A and B, new antifungal antibiotics: III. Mode of action of leptomycin B on Schizosaccharomyces pombe. J. Antibiot. 38:1985;1573-1580.
    • (1985) J. Antibiot. , vol.38 , pp. 1573-1580
    • Hamamoto, T.1    Gunji, S.2    Tsuji, H.3    Beppu, T.4
  • 36
    • 0028318159 scopus 로고
    • Leptomycin B targets a regulatory cascade of CRM1, a fission yeast nuclear protein, involved in control of higher order chromosome structure and gene expression
    • Nishi K., Yoshida M., Fujiwara D., Nishikawa M., Horinouchi S., Beppu T. Leptomycin B targets a regulatory cascade of CRM1, a fission yeast nuclear protein, involved in control of higher order chromosome structure and gene expression. J. Biol. Chem. 269:1994;6320-6324.
    • (1994) J. Biol. Chem. , vol.269 , pp. 6320-6324
    • Nishi, K.1    Yoshida, M.2    Fujiwara, D.3    Nishikawa, M.4    Horinouchi, S.5    Beppu, T.6
  • 39
    • 0035885933 scopus 로고    scopus 로고
    • Reduction in drug-induced DNA double-strand breaks associated with β1 integrin-mediated adhesion correlates with drug resistance in U937 cells
    • Hazlehurst L.A., Valkov N.I., Wisner L., Storey J.A., Boulware D., Sullivan D.M., Dalton W.S. Reduction in drug-induced DNA double-strand breaks associated with β1 integrin-mediated adhesion correlates with drug resistance in U937 cells. Blood. 98:2001;1897-1903.
    • (2001) Blood , vol.98 , pp. 1897-1903
    • Hazlehurst, L.A.1    Valkov, N.I.2    Wisner, L.3    Storey, J.A.4    Boulware, D.5    Sullivan, D.M.6    Dalton, W.S.7
  • 40
    • 0028091270 scopus 로고
    • Altered subcellular distribution of topoisomerase IIα in a drug-resistant human small cell lung cancer cell line
    • Feldhoff P.W., Mirski S.L., Cole S.C., Sullivan D.M. Altered subcellular distribution of topoisomerase IIα in a drug-resistant human small cell lung cancer cell line. Cancer Res. 54:1994;756.
    • (1994) Cancer Res. , vol.54 , pp. 756
    • Feldhoff, P.W.1    Mirski, S.L.2    Cole, S.C.3    Sullivan, D.M.4
  • 41
    • 0030967776 scopus 로고    scopus 로고
    • Quantitative immunofluorescence and immunoelectron microscopy of the topoisomerase IIα associated with the nuclear matrices from wild-type and drug-resistant Chinese hamster ovary cell lines
    • Valkov N.I., Gump J.L., Sullivan D.M. Quantitative immunofluorescence and immunoelectron microscopy of the topoisomerase IIα associated with the nuclear matrices from wild-type and drug-resistant Chinese hamster ovary cell lines. J. Cell. Biochem. 67:1997;112-130.
    • (1997) J. Cell. Biochem. , vol.67 , pp. 112-130
    • Valkov, N.I.1    Gump, J.L.2    Sullivan, D.M.3
  • 42
    • 0028819988 scopus 로고
    • Selective use of an alternative stop codon and polyadenylation signal within intron sequences leads to a truncated topoisomerase IIα messenger RNA and protein in human HL-60 leukemia cells selected for resistance to mitoxantrone
    • Harker G.W., Slade L.D., Parr R.L., Holguin M.H. Selective use of an alternative stop codon and polyadenylation signal within intron sequences leads to a truncated topoisomerase IIα messenger RNA and protein in human HL-60 leukemia cells selected for resistance to mitoxantrone. Cancer Res. 55:1995;4962-4971.
    • (1995) Cancer Res. , vol.55 , pp. 4962-4971
    • Harker, G.W.1    Slade, L.D.2    Parr, R.L.3    Holguin, M.H.4
  • 43
    • 0033563317 scopus 로고    scopus 로고
    • 5 tail anchors and stabilizes subdomains of human DNA topoisomerase IIα in the cytoplasm of retrovirally infected mammalian cells
    • 5 tail anchors and stabilizes subdomains of human DNA topoisomerase IIα in the cytoplasm of retrovirally infected mammalian cells. Exp. Cell Res. 248:1999;308-319.
    • (1999) Exp. Cell Res. , vol.248 , pp. 308-319
    • Soltermann, A.1    Ernst, A.2    Leroy, D.3    Stahel, R.A.4    Gasser, S.M.5


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