Quantitative, fluorescence-based in-situ assessment of protein expression

Methods in Molecular Biology

Volumn 520, Issue , 2009, Pages 163-175

  Moeder, Christopher B ^a   Giltnane, Jennifer M ^b   Moulis, Sharon Pozner ^c   Rimm, David L ^a  

^a YALE UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b VANDERBILT UNIVERSITY SCHOOL OF MEDICINE   (United States)

^c Merrimack Pharmceuticals   (United States)

Author keywords

AQUA; Biomarkers; Immunohistochemistry; Quantitative analysis; Tissue microarrays

Indexed keywords

ESTROGEN RECEPTOR; PROTEIN;

ARTICLE; CELL LINE; COMPUTER PROGRAM; FLUORESCENCE; HUMAN; IMMUNOHISTOCHEMISTRY; METABOLISM; METHODOLOGY; REGRESSION ANALYSIS; REPRODUCIBILITY; STANDARD;

CELL LINE; FLUORESCENCE; HUMANS; IMMUNOHISTOCHEMISTRY; PROTEINS; RECEPTORS, ESTROGEN; REGRESSION ANALYSIS; REPRODUCIBILITY OF RESULTS; SOFTWARE;

EID: 65649138059     PISSN: 10643745     EISSN: None     Source Type: Book Series    
DOI: 10.1007/978-1-60327-811-9_12     Document Type: Article

References (12)

1. McCarty, K. S., Jr., Szabo, E., Flowers, J. L., Cox, E. B., Leight, G. S., Miller, L., Konrath, J., Soper, J. T., Budwit, D. A., Creasman, W. T., et al. (1986) Use of a monoclonal anti-estrogen receptor antibody in the immunohisto-chemical evaluation of human tumors. Cancer Res 46, 4244s-48s. (Pubitemid 16041242)
2. Allred, D. C., Harvey, J. M., Berardo, M., and Clark, G. M. (1998) Prognostic and predictive factors in breast cancer by immunohistochem-ical analysis. Mod Pathol 11, 155-68. (Pubitemid 28144151)
3. Wolf f, A. C., Hammond, M. E., Schwar tz, J. N., Hagerty, K. L., Allred, D. C., Cote, R. J., Dowsett, M., Fitzgibbons, P. L., Hanna, W. M., Langer, A., McShane, L. M., Paik, S., Pegram, M. D., Perez, E. A., Press, M. F., Rhodes, A., Sturgeon, C., Taube, S. E., Tubbs, R., Vance, G. H., van de Vijver, M., Wheeler, T. M., and Hayes, D. F. (2007) American Society of Clinical Oncology/College of American Pathologists guideline recommendations for human epidermal growth factor receptor 2 testing in breast cancer. J Clin Oncol 25, 118-45. (Pubitemid 350003059)
4. Elkin, E. B., Weinstein, M. C., Winer, E. P., Kuntz, K. M., Schnitt, S. J., and Weeks, J. C. (2004) HER-2 testing and trastuzumab therapy for metastatic breast cancer: a cost-effectiveness analysis. J Clin Oncol 22, 854-63. (Pubitemid 41103597)
5. Camp, R. L., Chung, G. G., and Rimm, D. L. (2002) Automated subcellular localization and quantification of protein expression in tissue microarrays. Nat Med 8, 1323-7. (Pubitemid 35373567)
6. McCabe, A., Dolled-Filhart, M., Camp, R. L., and Rimm, D. L. (2005) Automated quantitative analysis (AQUA) of in situ protein expression, antibody concentration, and prognosis. J Natl Cancer Inst 97, 1808-15. (Pubitemid 43033901)
7. Cregger, M., Berger, A. J., and Rimm, D. L. (2006) Immunohistochemistry and quantitative analysis of protein expression. Arch Pathol Lab Med 130, 1026-30. (Pubitemid 44061434)
8. Chung, G. G., Zerkowski, M. P., Ghosh, S., Camp, R. L., and Rimm, D. L. (2007) Quantitative analysis of estrogen receptor heterogeneity in breast cancer. Lab Invest 87, 662-9. (Pubitemid 46920099)
9. Nielsen, T. O., Hsu, F. D., O'Connell, J. X., Gilks, C. B., Sorensen, P. H., Linn, S., West, R. B., Liu, C. L., Botstein, D., Brown, P. O., and van de Rijn, M. (2003) Tissue microarray validation of epidermal growth factor receptor and SALL2 in synovial sarcoma with comparison to tumors of similar histology. Am J Pathol 163, 1449-56. (Pubitemid 37175092)
10. Torhorst, J., Bucher, C., Kononen, J., Haas, P., Zuber, M., Kochli, O. R., Mross, F., Dieterich, H., Moch, H., Mihatsch, M., Kallioniemi, O. P., and Sauter, G. (2001) Tissue microarrays for rapid linking of molecular changes to clinical endpoints. Am J Pathol 159, 2249-56. (Pubitemid 33104278)
11. Camp, R. L., Charette, L. A., and Rimm, D. L. (2000) Validation of tissue microarray technology in breast carcinoma. Lab Invest 80, 1943-9. (Pubitemid 32012762)
12. Pozner-Moulis, S., Cregger, M., Camp, R. L., and Rimm, D. L. (2007) Antibody validation by quantitative analysis of protein expression using expression of Met in breast cancer as a model. Lab Invest 87, 251-60. (Pubitemid 46353942)