Septins promote dendrite and axon development by negatively regulating microtubule stability via HDAC6-mediated deacetylation

Nature Communications

Volumn 4, Issue , 2013, Pages

  Ageta Ishihara, Natsumi ^a   Miyata, Takaki ^b   Ohshima, Chika ^a   Watanabe, Masahiko ^c   Sato, Yoshikatsu ^a   Hamamura, Yuki ^a   Higashiyama, Tetsuya ^a   Mazitschek, Ralph ^d   Bito, Haruhiko ^e   Kinoshita, Makoto ^a  

^a NAGOYA UNIVERSITY   (Japan)

^b NAGOYA UNIVERSITY GRADUATE SCHOOL OF MEDICINE   (Japan)

^c HOKKAIDO UNIVERSITY GRADUATE SCHOOL OF MEDICINE   (Japan)

^d MASSACHUSETTS GENERAL HOSPITAL   (United States)

^e UNIVERSITY OF TOKYO   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

ALPHA TUBULIN; HISTONE DEACETYLASE 6; SEPTIN;

BIOLOGICAL DEVELOPMENT; BRAIN; ENZYME ACTIVITY; FUNCTIONAL ROLE; GROWTH RATE; NEUROLOGY; PHENOTYPE; PROTEIN; RODENT;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; CYTOSKELETON; DEACETYLATION; DENDRITE; EMBRYO; ENZYME ACTIVITY; GROWTH RETARDATION; HEMISPHERE; IN VITRO STUDY; MICROTUBULE; MOUSE; NERVE CELL DIFFERENTIATION; NERVE GROWTH; NONHUMAN; PHENOTYPE; POSTNATAL DEVELOPMENT;

ACETYLATION; ANIMALS; ANIMALS, NEWBORN; AXONS; CEREBRAL CORTEX; DENDRITES; FETUS; GENE EXPRESSION REGULATION, DEVELOPMENTAL; GENE KNOCKDOWN TECHNIQUES; GENE KNOCKOUT TECHNIQUES; HISTONE DEACETYLASES; MICE; MICROTUBULES; NEUROGENESIS; SEPTINS; SIGNAL TRANSDUCTION; TUBULIN;

EID: 84885615382     PISSN: None     EISSN: 20411723     Source Type: Journal    
DOI: 10.1038/ncomms3532     Document Type: Article

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