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Volumn 44, Issue 2, 2013, Pages 496-503

Differential gene expression in ERα-positive and ERα-negative breast cancer cells upon leptin stimulation

Author keywords

Breast cancer; Estrogen receptor; Leptin; Whole genome microarray

Indexed keywords

ESTROGEN RECEPTOR ALPHA; LEPTIN; STAT3 PROTEIN;

EID: 84885609505     PISSN: 1355008X     EISSN: 15590100     Source Type: Journal    
DOI: 10.1007/s12020-013-9897-y     Document Type: Article
Times cited : (8)

References (47)
  • 1
    • 84864855395 scopus 로고    scopus 로고
    • Obesity and the risk for premenopausal and postmenopausal breast cancer
    • 10.1158/1940-6207.CAPR-12-0091
    • G.L. Anderson, M.L. Neuhouser, Obesity and the risk for premenopausal and postmenopausal breast cancer. Cancer Prev. Res. (Phila.) 5, 515-521 (2012)
    • (2012) Cancer Prev. Res. (Phila.) , vol.5 , pp. 515-521
    • Anderson, G.L.1    Neuhouser, M.L.2
  • 2
    • 84856502414 scopus 로고    scopus 로고
    • Obesity and breast cancer: A clinical biochemistry perspective
    • 22178111 10.1016/j.clinbiochem.2011.11.016 1:CAS:528:DC%2BC38XhvFKltbw%3D
    • A. Ray, M.P. Cleary, Obesity and breast cancer: a clinical biochemistry perspective. Clin. Biochem. 45, 189-197 (2012)
    • (2012) Clin. Biochem. , vol.45 , pp. 189-197
    • Ray, A.1    Cleary, M.P.2
  • 3
    • 33644916156 scopus 로고    scopus 로고
    • Leptin and cancer
    • 16110483 10.1002/jcp.20472 1:CAS:528:DC%2BD28XisFOjsr4%3D
    • C. Garofalo, E. Surmacz, Leptin and cancer. J. Cell. Physiol. 207, 12-22 (2006)
    • (2006) J. Cell. Physiol. , vol.207 , pp. 12-22
    • Garofalo, C.1    Surmacz, E.2
  • 5
    • 79958729402 scopus 로고    scopus 로고
    • Increased risk of contralateral breast cancers among overweight and obese women: A time-dependent association
    • 20872242 10.1007/s10549-010-1153-z
    • B. Majed, A. Dozol, L. Ribassin-Majed, K. Senouci, B. Asselain, Increased risk of contralateral breast cancers among overweight and obese women: a time-dependent association. Breast Cancer Res. Treat. 126, 729-738 (2011)
    • (2011) Breast Cancer Res. Treat. , vol.126 , pp. 729-738
    • Majed, B.1    Dozol, A.2    Ribassin-Majed, L.3    Senouci, K.4    Asselain, B.5
  • 6
    • 30044434035 scopus 로고    scopus 로고
    • Intracellular signalling pathways activated by leptin
    • 16336196 10.1042/BJ20051578 1:CAS:528:DC%2BD28XivVKnsg%3D%3D
    • G. Fruhbeck, Intracellular signalling pathways activated by leptin. Biochem. J. 393, 7-20 (2006)
    • (2006) Biochem. J. , vol.393 , pp. 7-20
    • Fruhbeck, G.1
  • 7
    • 76149142449 scopus 로고    scopus 로고
    • Leptin and adiponectin: New players in the field of tumor cell and leukocyte migration
    • 20030801 10.1186/1478-811X-7-27
    • K. Lang, J. Ratke, Leptin and adiponectin: new players in the field of tumor cell and leukocyte migration. Cell Commun. Signal. 7, 27 (2009)
    • (2009) Cell Commun. Signal. , vol.7 , pp. 27
    • Lang, K.1    Ratke, J.2
  • 8
    • 84885592621 scopus 로고    scopus 로고
    • The role of leptin in obesity and the potential for leptin replacement therapy
    • H. Feng, L. Zheng, Z. Feng, Y. Zhao, N. Zhang, The role of leptin in obesity and the potential for leptin replacement therapy. Endocrine (2012)
    • (2012) Endocrine
    • Feng, H.1    Zheng, L.2    Feng, Z.3    Zhao, Y.4    Zhang, N.5
  • 10
    • 0031436148 scopus 로고    scopus 로고
    • Divergent signaling capacities of the long and short isoforms of the leptin receptor
    • 9405487 10.1074/jbc.272.51.32686 1:CAS:528:DyaK1cXisleqsA%3D%3D
    • C. Bjorbaek, S. Uotani, B. da Silva, J.S. Flier, Divergent signaling capacities of the long and short isoforms of the leptin receptor. J. Biol. Chem. 272, 32686-32695 (1997)
    • (1997) J. Biol. Chem. , vol.272 , pp. 32686-32695
    • Bjorbaek, C.1    Uotani, S.2    Da Silva, B.3    Flier, J.S.4
  • 12
    • 0033521595 scopus 로고    scopus 로고
    • STAT3 is required for the gp130-mediated full activation of the c-myc gene
    • 9874564 10.1084/jem.189.1.63 1:CAS:528:DyaK1MXjs1Ogtg%3D%3D
    • N. Kiuchi, K. Nakajima, M. Ichiba, T. Fukada, M. Narimatsu, K. Mizuno, M. Hibi, T. Hirano, STAT3 is required for the gp130-mediated full activation of the c-myc gene. J. Exp. Med. 189, 63-73 (1999)
    • (1999) J. Exp. Med. , vol.189 , pp. 63-73
    • Kiuchi, N.1    Nakajima, K.2    Ichiba, M.3    Fukada, T.4    Narimatsu, M.5    Mizuno, K.6    Hibi, M.7    Hirano, T.8
  • 13
    • 0034676267 scopus 로고    scopus 로고
    • Induction of p21WAF1/CIP1 and cyclin D1 expression by the Src oncoprotein in mouse fibroblasts: Role of activated STAT3 signaling
    • 11114718 10.1038/sj.onc.1203947 1:CAS:528:DC%2BD3cXosl2nu78%3D
    • D. Sinibaldi, W. Wharton, J. Turkson, T. Bowman, W.J. Pledger, R. Jove, Induction of p21WAF1/CIP1 and cyclin D1 expression by the Src oncoprotein in mouse fibroblasts: role of activated STAT3 signaling. Oncogene 19, 5419-5427 (2000)
    • (2000) Oncogene , vol.19 , pp. 5419-5427
    • Sinibaldi, D.1    Wharton, W.2    Turkson, J.3    Bowman, T.4    Pledger, W.J.5    Jove, R.6
  • 14
    • 20444446371 scopus 로고    scopus 로고
    • Identification of a genetic signature of activated signal transducer and activator of transcription 3 in human tumors
    • 15958548 10.1158/0008-5472.CAN-04-4281 1:CAS:528:DC%2BD2MXltFemtb8%3D
    • J.V. Alvarez, P.G. Febbo, S. Ramaswamy, M. Loda, A. Richardson, D.A. Frank, Identification of a genetic signature of activated signal transducer and activator of transcription 3 in human tumors. Cancer Res. 65, 5054-5062 (2005)
    • (2005) Cancer Res. , vol.65 , pp. 5054-5062
    • Alvarez, J.V.1    Febbo, P.G.2    Ramaswamy, S.3    Loda, M.4    Richardson, A.5    Frank, D.A.6
  • 15
    • 0036794395 scopus 로고    scopus 로고
    • Signal transducers and activators of transcription as downstream targets of nongenomic estrogen receptor actions
    • 12351686 10.1210/me.2002-0072 1:CAS:528:DC%2BD38XnsFKmurY%3D
    • L. Bjornstrom, M. Sjoberg, Signal transducers and activators of transcription as downstream targets of nongenomic estrogen receptor actions. Mol. Endocrinol. 16, 2202-2214 (2002)
    • (2002) Mol. Endocrinol. , vol.16 , pp. 2202-2214
    • Bjornstrom, L.1    Sjoberg, M.2
  • 18
    • 0042357145 scopus 로고    scopus 로고
    • Estrogen receptor alpha, a molecular switch converting transforming growth factor-alpha-mediated proliferation into differentiation in neuroblastoma cells
    • 12709435 10.1074/jbc.M301525200 1:CAS:528:DC%2BD3sXmsVOntLk%3D
    • P. Ciana, S. Ghisletti, P. Mussi, I. Eberini, E. Vegeto, A. Maggi, Estrogen receptor alpha, a molecular switch converting transforming growth factor-alpha-mediated proliferation into differentiation in neuroblastoma cells. J. Biol. Chem. 278, 31737-31744 (2003)
    • (2003) J. Biol. Chem. , vol.278 , pp. 31737-31744
    • Ciana, P.1    Ghisletti, S.2    Mussi, P.3    Eberini, I.4    Vegeto, E.5    Maggi, A.6
  • 19
    • 77953473305 scopus 로고    scopus 로고
    • Expression of estrogen receptor alpha increases leptin-induced STAT3 activity in breast cancer cells
    • 19876927 10.1002/ijc.25010 1:CAS:528:DC%2BC3cXlsVOrsLY%3D
    • N.A. Binai, A. Damert, G. Carra, S. Steckelbroeck, J. Lower, R. Lower, S. Wessler, Expression of estrogen receptor alpha increases leptin-induced STAT3 activity in breast cancer cells. Int. J. Cancer 127, 55-66 (2010)
    • (2010) Int. J. Cancer , vol.127 , pp. 55-66
    • Binai, N.A.1    Damert, A.2    Carra, G.3    Steckelbroeck, S.4    Lower, J.5    Lower, R.6    Wessler, S.7
  • 20
    • 30944440261 scopus 로고    scopus 로고
    • Identification of estrogen receptor ligands leading to activation of non-genomic signaling pathways while exhibiting only weak transcriptional activity
    • 16203130 10.1016/j.jsbmb.2005.08.003 1:CAS:528:DC%2BD28XmsVGluw%3D%3D
    • S. Wessler, C. Otto, N. Wilck, V. Stangl, K.H. Fritzemeier, Identification of estrogen receptor ligands leading to activation of non-genomic signaling pathways while exhibiting only weak transcriptional activity. J. Steroid Biochem. Mol. Biol. 98, 25-35 (2006)
    • (2006) J. Steroid Biochem. Mol. Biol. , vol.98 , pp. 25-35
    • Wessler, S.1    Otto, C.2    Wilck, N.3    Stangl, V.4    Fritzemeier, K.H.5
  • 21
    • 0024440781 scopus 로고
    • The cloned human oestrogen receptor contains a mutation which alters its hormone binding properties
    • 2792078 1:CAS:528:DyaL1MXkslansrk%3D
    • L. Tora, A. Mullick, D. Metzger, M. Ponglikitmongkol, I. Park, P. Chambon, The cloned human oestrogen receptor contains a mutation which alters its hormone binding properties. EMBO J. 8, 1981-1986 (1989)
    • (1989) EMBO J. , vol.8 , pp. 1981-1986
    • Tora, L.1    Mullick, A.2    Metzger, D.3    Ponglikitmongkol, M.4    Park, I.5    Chambon, P.6
  • 22
  • 24
    • 44949231424 scopus 로고    scopus 로고
    • Analyzing real-time PCR data by the comparative C(T) method
    • 18546601 10.1038/nprot.2008.73 1:CAS:528:DC%2BD1cXmvVemt7c%3D
    • T.D. Schmittgen, K.J. Livak, Analyzing real-time PCR data by the comparative C(T) method. Nat. Protoc. 3, 1101-1108 (2008)
    • (2008) Nat. Protoc. , vol.3 , pp. 1101-1108
    • Schmittgen, T.D.1    Livak, K.J.2
  • 26
    • 77953582276 scopus 로고    scopus 로고
    • Cellular and molecular crosstalk between leptin receptor and estrogen receptor-{alpha} in breast cancer: Molecular basis for a novel therapeutic setting
    • 20410173 10.1677/ERC-09-0340 1:CAS:528:DC%2BC3cXptV2lsr0%3D
    • R. Fusco, M. Galgani, C. Procaccini, R. Franco, G. Pirozzi, L. Fucci, P. Laccetti, G. Matarese, Cellular and molecular crosstalk between leptin receptor and estrogen receptor-{alpha} in breast cancer: molecular basis for a novel therapeutic setting. Endocr. Relat. Cancer 17, 373-382 (2010)
    • (2010) Endocr. Relat. Cancer , vol.17 , pp. 373-382
    • Fusco, R.1    Galgani, M.2    Procaccini, C.3    Franco, R.4    Pirozzi, G.5    Fucci, L.6    Laccetti, P.7    Matarese, G.8
  • 29
    • 84879555168 scopus 로고    scopus 로고
    • Leptin stimulation of cell cycle and inhibition of apoptosis gene and protein expression in OVCAR-3 ovarian cancer cells
    • doi: 10.1007/s12020-012-9788-7
    • A. Ptak, E. Kolaczkowska, E. L. Gregoraszczuk, Leptin stimulation of cell cycle and inhibition of apoptosis gene and protein expression in OVCAR-3 ovarian cancer cells. Endocrine (2012). doi: 10.1007/s12020-012-9788-7
    • (2012) Endocrine
    • Ptak, A.1    Kolaczkowska, E.2    Gregoraszczuk, E.L.3
  • 34
    • 56849130281 scopus 로고    scopus 로고
    • Leptin-regulated gene expression in MCF-7 breast cancer cells: Mechanistic insights into leptin-regulated mammary tumor growth and progression
    • 18715880 10.1677/JOE-08-0215 1:CAS:528:DC%2BD1cXhsVClsb7M
    • C.N. Perera, H.G. Chin, N. Duru, I.G. Camarillo, Leptin-regulated gene expression in MCF-7 breast cancer cells: mechanistic insights into leptin-regulated mammary tumor growth and progression. J. Endocrinol. 199, 221-233 (2008)
    • (2008) J. Endocrinol. , vol.199 , pp. 221-233
    • Perera, C.N.1    Chin, H.G.2    Duru, N.3    Camarillo, I.G.4
  • 35
    • 0035783047 scopus 로고    scopus 로고
    • Developmental roles of the glypicans
    • 11292377 10.1006/scdb.2000.0240
    • B. De Cat, G. David, Developmental roles of the glypicans. Semin. Cell Dev. Biol. 12, 117-125 (2001)
    • (2001) Semin. Cell Dev. Biol. , vol.12 , pp. 117-125
    • De Cat, B.1    David, G.2
  • 36
    • 79955162643 scopus 로고    scopus 로고
    • A lung cancer gene GPC5 could also be crucial in breast cancer
    • 21396872 10.1016/j.ymgme.2011.02.005 1:CAS:528:DC%2BC3MXltFeksLg%3D
    • C. Zhang, S. Zhang, D. Zhang, Z. Zhang, Y. Xu, S. Liu, A lung cancer gene GPC5 could also be crucial in breast cancer. Mol. Genet. Metab. 103, 104-105 (2011)
    • (2011) Mol. Genet. Metab. , vol.103 , pp. 104-105
    • Zhang, C.1    Zhang, S.2    Zhang, D.3    Zhang, Z.4    Xu, Y.5    Liu, S.6
  • 37
    • 56949084416 scopus 로고    scopus 로고
    • Molecular evolution of the cadherin superfamily
    • 18848899 10.1016/j.biocel.2008.09.027 1:CAS:528:DC%2BD1cXhsVCgsL7J
    • P. Hulpiau, F. van Roy, Molecular evolution of the cadherin superfamily. Int. J. Biochem. Cell Biol. 41, 349-369 (2009)
    • (2009) Int. J. Biochem. Cell Biol. , vol.41 , pp. 349-369
    • Hulpiau, P.1    Van Roy, F.2
  • 38
    • 84865031797 scopus 로고    scopus 로고
    • Prevalence and clinical features of hearing loss patients with CDH23 mutations: A large cohort study
    • 22899989 10.1371/journal.pone.0040366 1:CAS:528:DC%2BC38Xht1Olsb%2FF
    • M. Miyagawa, S.Y. Nishio, S. Usami, Prevalence and clinical features of hearing loss patients with CDH23 mutations: a large cohort study. PLoS ONE 7, e40366 (2012)
    • (2012) PLoS ONE , vol.7 , pp. 40366
    • Miyagawa, M.1    Nishio, S.Y.2    Usami, S.3
  • 39
    • 84857834773 scopus 로고    scopus 로고
    • Cadherin-23 mediates heterotypic cell-cell adhesion between breast cancer epithelial cells and fibroblasts
    • 22413011 10.1371/journal.pone.0033289 1:CAS:528:DC%2BC38XktF2gs7s%3D
    • M. Apostolopoulou, L. Ligon, Cadherin-23 mediates heterotypic cell-cell adhesion between breast cancer epithelial cells and fibroblasts. PLoS ONE 7, e33289 (2012)
    • (2012) PLoS ONE , vol.7 , pp. 33289
    • Apostolopoulou, M.1    Ligon, L.2
  • 40
    • 0026805954 scopus 로고
    • Cloning, primary sequence and chromosomal localization of human FMO2, a new member of the flavin-containing mono-oxygenase family
    • 1417778 1:CAS:528:DyaK3sXks1Knsro%3D
    • C.T. Dolphin, E.A. Shephard, S. Povey, R.L. Smith, I.R. Phillips, Cloning, primary sequence and chromosomal localization of human FMO2, a new member of the flavin-containing mono-oxygenase family. Biochem. J. 287, 261-267 (1992)
    • (1992) Biochem. J. , vol.287 , pp. 261-267
    • Dolphin, C.T.1    Shephard, E.A.2    Povey, S.3    Smith, R.L.4    Phillips, I.R.5
  • 41
    • 51749119672 scopus 로고    scopus 로고
    • CPA6, FMO2, LGI1, SIAT1 and TNC are differentially expressed in early- and late-stage oral squamous cell carcinoma - A pilot study
    • 18234543 10.1016/j.oraloncology.2007.10.011 1:CAS:528:DC%2BD1cXhtFekurvI
    • F. Fialka, R.M. Gruber, R. Hitt, L. Opitz, E. Brunner, H. Schliephake, F.J. Kramer, CPA6, FMO2, LGI1, SIAT1 and TNC are differentially expressed in early- and late-stage oral squamous cell carcinoma - a pilot study. Oral Oncol. 44, 941-948 (2008)
    • (2008) Oral Oncol. , vol.44 , pp. 941-948
    • Fialka, F.1    Gruber, R.M.2    Hitt, R.3    Opitz, L.4    Brunner, E.5    Schliephake, H.6    Kramer, F.J.7
  • 42
    • 33646712592 scopus 로고    scopus 로고
    • The role of flavin-containing monooxygenase (FMO) in the metabolism of tamoxifen and other tertiary amines
    • 16684653 10.1080/03602530600569919 1:CAS:528:DC%2BD28XktlWlu7k%3D
    • S.K. Krueger, J.E. Vandyke, D.E. Williams, R.N. Hines, The role of flavin-containing monooxygenase (FMO) in the metabolism of tamoxifen and other tertiary amines. Drug Metab. Rev. 38, 139-147 (2006)
    • (2006) Drug Metab. Rev. , vol.38 , pp. 139-147
    • Krueger, S.K.1    Vandyke, J.E.2    Williams, D.E.3    Hines, R.N.4
  • 43
    • 0026319776 scopus 로고
    • Cytochrome P-450-mediated activation and irreversible binding of the antiestrogen tamoxifen to proteins in rat and human liver: Possible involvement of flavin-containing monooxygenases in tamoxifen activation
    • 1933868 1:CAS:528:DyaK38XjsVOhug%3D%3D
    • C. Mani, D. Kupfer, Cytochrome P-450-mediated activation and irreversible binding of the antiestrogen tamoxifen to proteins in rat and human liver: possible involvement of flavin-containing monooxygenases in tamoxifen activation. Cancer Res. 51, 6052-6058 (1991)
    • (1991) Cancer Res. , vol.51 , pp. 6052-6058
    • Mani, C.1    Kupfer, D.2
  • 44
    • 66449115901 scopus 로고    scopus 로고
    • STAT3-stathmin interactions control microtubule dynamics in migrating T-cells
    • 19251695 10.1074/jbc.M807761200 1:CAS:528:DC%2BD1MXltVClsro%3D
    • N.K. Verma, J. Dourlat, A.M. Davies, A. Long, W.Q. Liu, C. Garbay, D. Kelleher, Y. Volkov, STAT3-stathmin interactions control microtubule dynamics in migrating T-cells. J. Biol. Chem. 284, 12349-12362 (2009)
    • (2009) J. Biol. Chem. , vol.284 , pp. 12349-12362
    • Verma, N.K.1    Dourlat, J.2    Davies, A.M.3    Long, A.4    Liu, W.Q.5    Garbay, C.6    Kelleher, D.7    Volkov, Y.8
  • 45
    • 34250217027 scopus 로고    scopus 로고
    • Constitutively activated Stat3 induces tumorigenesis and enhances cell motility of prostate epithelial cells through integrin beta 6
    • 17438134 10.1128/MCB.02404-06 1:CAS:528:DC%2BD2sXmvFansLc%3D
    • J. Azare, K. Leslie, H. Al-Ahmadie, W. Gerald, P.H. Weinreb, S.M. Violette, J. Bromberg, Constitutively activated Stat3 induces tumorigenesis and enhances cell motility of prostate epithelial cells through integrin beta 6. Mol. Cell. Biol. 27, 4444-4453 (2007)
    • (2007) Mol. Cell. Biol. , vol.27 , pp. 4444-4453
    • Azare, J.1    Leslie, K.2    Al-Ahmadie, H.3    Gerald, W.4    Weinreb, P.H.5    Violette, S.M.6    Bromberg, J.7
  • 46
    • 30944435466 scopus 로고    scopus 로고
    • Stat3 regulates microtubules by antagonizing the depolymerization activity of stathmin
    • 16401721 10.1083/jcb.200503021 1:CAS:528:DC%2BD28XntV2isA%3D%3D
    • D.C. Ng, B.H. Lin, C.P. Lim, G. Huang, T. Zhang, V. Poli, X. Cao, Stat3 regulates microtubules by antagonizing the depolymerization activity of stathmin. J. Cell Biol. 172, 245-257 (2006)
    • (2006) J. Cell Biol. , vol.172 , pp. 245-257
    • Ng, D.C.1    Lin, B.H.2    Lim, C.P.3    Huang, G.4    Zhang, T.5    Poli, V.6    Cao, X.7
  • 47
    • 79952224367 scopus 로고    scopus 로고
    • STAT3 Inhibition by microtubule-targeted drugs: Dual molecular effects of chemotherapeutic agents
    • 21949561 1:CAS:528:DC%2BC3MXks1Krsrk%3D
    • S.R. Walker, M. Chaudhury, D.A. Frank, STAT3 Inhibition by microtubule-targeted drugs: dual molecular effects of chemotherapeutic agents. Mol. Cell. Pharmacol. 3, 13-19 (2011)
    • (2011) Mol. Cell. Pharmacol. , vol.3 , pp. 13-19
    • Walker, S.R.1    Chaudhury, M.2    Frank, D.A.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.