-
1
-
-
0031588180
-
Randomised trial of two regimens of chemotherapy in operable osteosarcoma: A study of the European Osteosarcoma Intergroup
-
DOI 10.1016/S0140-6736(97)02307-6
-
Souhami RL, Craft AW, Van der Eijken JW, et al. Randomized trial of regimens of chemotherapy in operable osteosarcoma: a study of the European Osteosarcoma Intergroup. Lancet 1997;350:911-17 . An important study showing that ADM + CDDP chemotherapy is effective for osteosarcoma. (Pubitemid 27420527)
-
(1997)
Lancet
, vol.350
, Issue.9082
, pp. 911-917
-
-
Souhami, R.L.1
Craft, A.W.2
Van Der Eijken, J.W.3
Nooij, M.4
Spooner, D.5
Bramwell, V.H.C.6
Wierzbicki, R.7
Malcolm, A.J.8
Kirkpatrick, A.9
Uscinska, B.M.10
Van Glabbeke, M.11
Machin, D.12
-
2
-
-
84864340595
-
Extraskeletal osteosarcoma of the breast in an adolescent girl
-
Zils K, Ebner F, Ott M, et al. Extraskeletal osteosarcoma of the breast in an adolescent girl. J Pediatr Hematol Oncol 2012;34:e261-3
-
(2012)
J Pediatr Hematol Oncol
, vol.34
-
-
Zils, K.1
Ebner, F.2
Ott, M.3
-
3
-
-
84863660155
-
Extraskeletal osteosarcoma of penis: A case report
-
Wu CZ, Li CM, Han S, et al. Extraskeletal osteosarcoma of penis: a case report. Chin J Cancer Res 2012;24:164-6
-
(2012)
Chin J Cancer Res
, vol.24
, pp. 164-166
-
-
Wu, C.Z.1
Li, C.M.2
Han, S.3
-
4
-
-
0002093123
-
Osteosrcoma
-
In: Dorfman HD, Czerniak B, editors. Mosby; St. Louis:
-
Dorfman HD, Czerniak B. Osteosrcoma. In: Dorfman HD, Czerniak B, editors. Bone tumors. Mosby. St. Louis: 1998. p. 128-252
-
(1998)
Bone Tumors.
, pp. 128-252
-
-
Dorfman, H.D.1
Czerniak, B.2
-
5
-
-
0036467661
-
Prognostic factors in high-grade osteosarcoma of the extremities or trunk: An analysis of 1,702 patients treated on neoadjuvant cooperative osteosarcoma study group protocols
-
DOI 10.1200/JCO.20.3.776
-
Bielack SS, Kempf-Bielack B, Delling G, et al. Prognostic factors in high-grade osteosarcoma of the extremities or trunk: an analysis of 1,702 patients treated on neoadjuvant cooperative osteosarcoma study group protocols. J Clin Oncol 2002;20:776-90 (Pubitemid 34111386)
-
(2002)
Journal of Clinical Oncology
, vol.20
, Issue.3
, pp. 776-790
-
-
Bielack, S.S.1
Kempf-Bielack, B.2
Delling, G.3
Exner, G.U.4
Flege, S.5
Helmke, K.6
Kotz, R.7
Salzer-Kuntschik, M.8
Wemer, M.9
Winkelmann, W.10
Zoubek, A.11
Jurgens, H.12
Winkler, K.13
-
6
-
-
0015460906
-
The therapy of osteogenic sarcoma- current status and thoughts for the future
-
Friedman MA, Carter SK. The therapy of osteogenic sarcoma- current status and thoughts for the future. J Surg Oncol 1972;4:482-510
-
(1972)
J Surg Oncol
, vol.4
, pp. 482-510
-
-
Friedman, M.A.1
Carter, S.K.2
-
7
-
-
0015442331
-
Recent advances in the chemotherapy of metastatic osteogenic sarcoma
-
Jaffe N. Recent advances in the chemotherapy of metastatic osteogenic sarcoma. Cancer 1972;30:1627-31
-
(1972)
Cancer
, vol.30
, pp. 1627-1631
-
-
Jaffe, N.1
-
8
-
-
0016242550
-
Adjuvant methotrexate and citrovorum-factor treatment of osteogenic sarcoma
-
A landmark study showing that chemotherapy is effective for osteosarcoma and that it can improve the survival of patients with osteosarcoma
-
Jaffe N, Frei E III, Traggis D, et al. Adjuvant methotrexate and citrovorum-factor treatment of osteogenic sarcoma. N Engl J Med 1974;291:994-7 .. A landmark study showing that chemotherapy is effective for osteosarcoma and that it can improve the survival of patients with osteosarcoma.
-
(1974)
N Engl J Med
, vol.291
, pp. 994-997
-
-
Jaffe, N.1
Frei III, E.2
Traggis, D.3
-
9
-
-
0016208984
-
Amputation and adriamycin in primary osteosarcoma
-
Cortes EP, Holland JF, Wang JJ, et al. Amputation and adriamycin in primary osteosarcoma. N Engl J Med 1974;291:998-1000
-
(1974)
N Engl J Med
, vol.291
, pp. 998-1000
-
-
Cortes, E.P.1
Holland, J.F.2
Wang, J.J.3
-
10
-
-
0018136131
-
Multi-drug adjuvant chemotherapy for osteosarcoma: Interim report of the Southwest Oncology Group studies
-
An important study showing that adjuvant multidrug chemotherapy is more effective for osteosarcoma
-
Stow WW, Gehan EA, Dyment PG, et al. Multi-drug adjuvant chemotherapy for osteosarcoma: interim report of the Southwest Oncology Group studies. Cancer Treat Rep 1978;62:265-70 . An important study showing that adjuvant multidrug chemotherapy is more effective for osteosarcoma.
-
(1978)
Cancer Treat Rep
, vol.62
, pp. 265-270
-
-
Stow, W.W.1
Gehan, E.A.2
Dyment, P.G.3
-
11
-
-
0018650014
-
Primary osteogenic sarcoma. The rationale for preoperative chemotherapy and delayed surgery
-
DOI 10.1002/1097-0142(197906) 43:6<2163::AID-CNCR2820430602>3.0. CO;2-S
-
Rosen G, Marcove RC, Caparros B, et al. Primary osteogenic sarcoma: the rationale for preoperative chemotherapy and delayed surgery. Cancer 1979;43:2163-77 . An important study that introduces two concepts: Preoperative chemotherapy should be added to postoperative adjuvant chemotherapy subsequent to a definitive diagnosis by biopsy; and chemotherapy should be continued until a custom prosthesis is made to reconstruct the affected limb. (Pubitemid 9246383)
-
(1979)
Cancer
, vol.43
, Issue.6
, pp. 2163-2177
-
-
Rosen, G.1
Marcove, R.C.2
Caparros, B.3
-
12
-
-
0020059356
-
Preoperative chemotherapy for osteogenic sarcoma: Selection of postoperative adjuvant chemotherapy based on the response of the primary tumor to preoperative chemotherapy
-
Rosen G, Caparros B, Huvos AG, et al. Preoperative chemotherapy for osteogenic sarcoma: selection of postoperative adjuvant chemotherapy based on the response of the primary tumor to preoperative chemotherapy. Cancer 1982;49:1221-30 .. A landmark study that reports the outcomes of one of the most famous chemotherapy protocols (T-10) and advocates use of neoadjuvant chemotherapy. (Pubitemid 12187826)
-
(1982)
Cancer
, vol.49
, Issue.6
, pp. 1221-1230
-
-
Rosen, G.1
Caparros, B.2
Huvos, A.G.3
-
13
-
-
0026503028
-
Chemotherapy for nonmetastatic osteogenic sarcoma: The memorial sloan-kettering osteogenic sarcoma: The memorial sloan-kettering experience
-
Meyers PA, Heller G, Healey JH, et al. Chemotherapy for nonmetastatic osteogenic sarcoma: the memorial sloan-kettering osteogenic sarcoma: the memorial sloan-kettering experience. J Clin Oncol 1992;10:5-15
-
(1992)
J Clin Oncol
, vol.10
, pp. 5-15
-
-
Meyers, P.A.1
Heller, G.2
Healey, J.H.3
-
14
-
-
0031861214
-
Intensification of preoperative chemotherapy for osteogenic sarcoma: Results of the Memorial Sloan-Kettering (T12) protocol
-
Meyers P, Gorlick R, Heller G, et al. Intensification of preoperative chemotherapy for osteogenic sarcoma: results of the Memorial Sloan-Kettering (T12) protocol. J Clin Oncol 1998;16:2452-8 (Pubitemid 28309040)
-
(1998)
Journal of Clinical Oncology
, vol.16
, Issue.7
, pp. 2452-2458
-
-
Meyers, P.A.1
Gorlick, R.2
Heller, G.3
Casper, E.4
Lane, J.5
Huvos, A.G.6
Healey, J.H.7
-
15
-
-
0026002081
-
Treatment of osteosarcoma of the extremities with the T-10 protocol, with emphasis on the effects of preoperative chemotherapy with single-agent highdose methotrexate: A Scandinavian Sarcoma Group Study
-
A clinical study in which the dose-response relationship for HD-MTX treatment is elucidated
-
Saeter G, Alvegard TA, Elomaa I, et al. Treatment of osteosarcoma of the extremities with the T-10 protocol, with emphasis on the effects of preoperative chemotherapy with single-agent highdose methotrexate: a Scandinavian Sarcoma Group Study. J Clin Oncol 1991;9:1766-75 . A clinical study in which the dose-response relationship for HD-MTX treatment is elucidated.
-
(1991)
J Clin Oncol
, vol.9
, pp. 1766-1775
-
-
Saeter, G.1
Alvegard, T.A.2
Elomaa, I.3
-
16
-
-
0029861534
-
Influence of methotrexate dose intensity on outcome of patients with high grade osteogenic osteosarcoma: Analysis of the literature
-
DOI 10.1002/(SICI)1097-0142(19961115) 78:10<2127::AID-CNCR13>3.0. CO;2-0
-
Delepine N, Delepine G, Bacci G, et al. Influence of methotrexate dose intensity on outcome of patients with high grade osteogenic osteosarcoma. Cancer 1996;78:2127-35 (Pubitemid 26367605)
-
(1996)
Cancer
, vol.78
, Issue.10
, pp. 2127-2135
-
-
Delepine, N.1
Delepine, G.2
Bacci, G.3
Rosen, G.4
Desbois, J.-C.5
-
17
-
-
0031022801
-
Treatment of nonmetastatic osteosarcoma of the extremity with preoperative and postoperative chemotherapy: A report from the Children's Cancer Group
-
Provisor AJ, Ettinger LJ, Nachman JB, et al. Treatment of nenmetastatic osteosarcoma of the extremity with preoperative and postoperative chemotherapy: a report from the Children's Cancer Group. J Clin Oncol 1997;15:76-84 .. A multicentre single-arm study that greatly contributed to the standardisation of chemotherapy and limb-sparing surgery in osteosarcoma treatment. (Pubitemid 27020560)
-
(1997)
Journal of Clinical Oncology
, vol.15
, Issue.1
, pp. 76-84
-
-
Provisor, A.J.1
Ettinger, L.J.2
Nachman, J.B.3
Krailo, M.D.4
Makley, J.T.5
Yunis, E.J.6
Huvos, A.G.7
Betcher, D.L.8
Baum, E.S.9
Kisker, C.T.10
Miser, J.S.11
-
18
-
-
0017836885
-
Cis-dichlorodiammineplatinum (II) in advanced osteogenic sarcoma
-
Ochs JJ, Freeman AI, Douglass HO. Jr, et al. Cis-dichlorodiammineplatinum (II) in advanced osteogenic sarcoma. Cancer Treat Rep 1978;62:239-45
-
(1978)
Cancer Treat Rep
, vol.62
, pp. 239-245
-
-
Ochs, J.J.1
Freeman, A.I.2
Douglass Jr., H.O.3
-
19
-
-
0018570543
-
Phase II study of cis-dichlorodiammineplatinum(II) in childhood osteosarcoma: Children's cancer study group report
-
Baum ES, Gaynon P, Greenberg L, et al. Phase II study of cisdichlorodiammineplatinum( II) in childhood osteosarcoma: children's Cancer Study Group Report. Cancer Treat Rep 1979;63:1621-7 (Pubitemid 10167768)
-
(1979)
Cancer Treatment Reports
, vol.63
, Issue.9-10
, pp. 1621-1627
-
-
Baum, E.S.1
Gaynon, P.2
Greenberg, L.3
-
20
-
-
0019350529
-
Adjuvant adriamycin and Cis-diamminedichloroplatinum (Cis-platinum) in primary osteosarcoma
-
DOI 10.1002/1097-0142(19810115) 47:2<248::AID-CNCR2820470208>3.0. CO;2-E
-
Ettinger LJ, Douglass HO Jr, Higby DJ, et al. Adjuvant adriamycin and cis-diamminedichloroplatinum (cisplatinum) in primary osteosarcoma. Cancer 1981;47:248-54 (Pubitemid 11179318)
-
(1981)
Cancer
, vol.47
, Issue.2
, pp. 248-254
-
-
Ettinger, L.J.1
Douglass Jr., H.O.2
Higby, D.J.3
-
21
-
-
0021830031
-
Comparison of intra-arterial cis-diamminedichloroplatinum II with high-dose methotrexate and citrovorum factor rescue in the treatment of primary osteosarcoma
-
Jaffe N, Robertson R, Ayala A, et al. Comparison of intra-arterial Cisdichlorodiammineplatinum II with high-dose methotrexate and citrovorum factor rescue in the treatment of primary osteosarcoma. J Clin oncol 1985;3:1101-4 (Pubitemid 15004831)
-
(1985)
Journal of Clinical Oncology
, vol.3
, Issue.8
, pp. 1101-1104
-
-
Jaffe, N.1
Robertson, R.2
Ayala, A.3
-
22
-
-
0021367709
-
A controlled pilot study of high-dose methotrexate as postsurgical adjuvant treatment for primary osteosarcoma
-
Edmonson JH, Green SJ, Ivins JC, et al. A controlled pilot study of high-dose methotrexate as postsurgical adjuvant treatment for primary osteosarcoma. J Clin Oncol 1984;2:152-6 (Pubitemid 14138401)
-
(1984)
Journal of Clinical Oncology
, vol.2
, Issue.3
, pp. 152-156
-
-
Edmonson, J.H.1
Green, S.J.2
Ivins, J.C.3
-
23
-
-
0022656434
-
The effect of adjuvant chemotherapy on relapse-free survival in patients with osteosarcoma of the extremity
-
Link MP, Goorin AM, Miser AW, et al. The effect of adjuvant chemotherapy on release-free survival in patients with osteosarcoma of the extremity. N Engl J Med 1986;314:1600-6 (Pubitemid 16118216)
-
(1986)
New England Journal of Medicine
, vol.314
, Issue.25
, pp. 1600-1606
-
-
Link, M.P.1
Goorin, A.M.2
Miser, A.W.3
-
24
-
-
0023125939
-
Adjuvant chemotherapy for osteosarcoma: A randomized prospective trial
-
Eilber F, Giuliano A, Eckardt J, et al. Adjuvant chemotherapy for osteosarcoma: a randomized prospective trial. J Clin Oncol 1987;5:21-6 (Pubitemid 17007852)
-
(1987)
Journal of Clinical Oncology
, vol.5
, Issue.1
, pp. 21-26
-
-
Eilber, F.1
Giuliano, A.2
Eckhardt, J.3
-
25
-
-
0026326203
-
Adjuvant chemotherapy of high-grade osteosarcoma of the extremity: Updated results of the multi-institutionalosteosarcoma study
-
A multicentre study in which the importance of adjuvant chemotherapy for osteosarcoma is indicated
-
Link MP, Goorin AM, Horowitz M, et al. Adjuvant chemotherapy of high-grade osteosarcoma of the extremity: updated results of the multi-institutionalosteosarcoma study. Clin Orthop 1991;270:8-14 .. A multicentre study in which the importance of adjuvant chemotherapy for osteosarcoma is indicated.
-
(1991)
Clin Orthop
, vol.270
, pp. 8-14
-
-
Link, M.P.1
Goorin, A.M.2
Horowitz, M.3
-
26
-
-
84885676758
-
Presentation of the collaborative osteosarcoma study COSS-77
-
Winkler K, Becker W, Kotz R, et al. Presentation of the collaborative osteosarcoma study COSS-77. Chimiother Oncol 1978;2:225-8
-
(1978)
Chimiother Oncol
, vol.2
, pp. 225-228
-
-
Winkler, K.1
Becker, W.2
Kotz, R.3
-
27
-
-
0021612290
-
Neoadjuvant chemotherapy for osteogenic sarcoma: Results of a cooperative German/Austrian study
-
Winkler K, Beron G, Kotz R, et al. Neoadjuvant chemotherapy for osteogenic sarcoma: results of a Cooperative German/Austrian Study. J Clin Oncol 1984;2:617-24 (Pubitemid 14025617)
-
(1984)
Journal of Clinical Oncology
, vol.2
, Issue.6
, pp. 617-624
-
-
Winkler, K.1
Beron, G.2
Kotz, R.3
-
28
-
-
0023852095
-
Neoadjuvant chemotherapy of osteosarcoma: Results of a randomized cooperative trial (COSS-82) with salvage chemotherapy based on histological tumor response
-
Winkler K, Beron G, delling G, et al. Neoadjuvant chemotherapy of osteosarcoma: results of a randomized cooperative trial (COSS-82) with salvage chemotherapy based on histological tumor response. J Clin Oncol 1988;6:329-37 (Pubitemid 18065939)
-
(1988)
Journal of Clinical Oncology
, vol.6
, Issue.2
, pp. 329-337
-
-
Winkler, K.1
Beron, G.2
Delling, G.3
Heise, U.4
Kabisch, H.5
Purfurst, C.6
Berger, J.7
Ritter, J.8
Jurgens, H.9
Gerein, V.10
Graf, N.11
Russe, W.12
Gruemayer, E.R.13
Ertelt, W.14
Kotz, R.15
Preusser, P.16
Prindull, G.17
Brandeis, W.18
Landbeck, G.19
-
29
-
-
0025155287
-
Effect of intraarterial versus intravenous cisplatin in addition to systemic doxorubicin, high-dose methotrexate, and ifosfamide on histologic tumor response in osteosarcoma (Study COSS-86)
-
Winkler K, Bielack S, Delling G, et al. Effect of intraarterial versus intravenous cisplatin in addition to systemic doxorubicin, high-dose methotrexate, and ifosfamide on histologic tumor response in osteosarcoma (Study COSS 86). Cancer 1990;66:1703-10 (Pubitemid 20381203)
-
(1990)
Cancer
, vol.66
, Issue.8
, pp. 1703-1710
-
-
Winkler, K.1
Bielack, S.2
Delling, G.3
Salzer-Kuntschik, M.4
Kotz, R.5
Greenshaw, C.6
Jurgens, H.7
Ritter, J.8
Kusnierz-Glaz, C.9
Erttmann, R.10
Gadicke, G.11
Graf, N.12
Ladenstein, R.13
Leyvraz, S.14
Mertens, R.15
Weinel, P.16
-
30
-
-
7344229308
-
Long-term results of the co-operative German-Austrian-Swiss osteosarcoma study group's protocol COSS-86 of intensive multidrug chemotherapy and surgery for osteosarcoma of the limbs
-
DOI 10.1023/A:1008391103132
-
Fuchs N, Bielack SS, Epler D, et al. Long-term results of the co-operative German-Austrian-Swiss osteosarcoma study group's protocol COSS-86 of intensive multidrug chemotherapy and surgery for osteosarcoma of the limbs. Ann Oncol 1998;9:893-9 (Pubitemid 28440449)
-
(1998)
Annals of Oncology
, vol.9
, Issue.8
, pp. 893-899
-
-
Fuchs, N.1
Bielack, S.S.2
Epler, D.3
Bieling, P.4
Delling, G.5
Korholz, D.6
Graf, N.7
Heise, U.8
Jurgens, H.9
Kotz, R.10
Salzer-Kuntschik, M.11
Weinel, P.12
Werner, M.13
Winkler, K.14
-
31
-
-
0027082303
-
A comparison of two short intensive adjuvant chemotherapy regimens in operable osteosarcoma of limbs in children and young adults: The first study of the European Osteosarcoma Intergroup
-
Bramwell VHC, Burgers M, Sneath R, et al. A comparison of two short intensive adjuvant chemotherapy regimens in operable osteosarcoma of limbs in children and young adults: the first study of the European Osteosarcoma Intergroup. J Clin Oncol 1992;10:1579-91 (Pubitemid 23057988)
-
(1992)
Journal of Clinical Oncology
, vol.10
, Issue.10
, pp. 1579-1591
-
-
Bramwell, V.H.C.1
Burgers, M.2
Sneath, R.3
Souhami, R.4
Van Oosterom, A.T.5
Voute, P.A.6
Rouesse, J.7
Spooner, D.8
Craft, A.W.9
Somers, R.10
Pringle, J.11
Malcolm, A.J.12
Van Der Eijken, J.13
Thomas, D.14
Uscinska, B.15
Machin, D.16
Van Glabbeke, M.17
-
32
-
-
33846981552
-
Improvement in histologic response but not survival in osteosarcoma patients treated with intensified chemotherapy: A randomized phase III trial of the European Osteosarcoma Intergroup
-
Lewis IJ, Nooij MA, Whelan J, et al. Improvement in histologic response but not survival in osteosarcoma patients treated with intensified chemotherapy: a randomized phase III trial of the European Osteosarcoma Intergroup. J Natl Cancer Inst 2007;99:112-28
-
(2007)
J Natl Cancer Inst
, vol.99
, pp. 112-128
-
-
Lewis, I.J.1
Nooij, M.A.2
Whelan, J.3
-
33
-
-
0021995651
-
High-dose ifosfamide in advanced osteosarcoma
-
Marti C, Kroner T, Remagen W, et al. High-dose ifosfamide in advanced osteosarcoma. Cancer Treat Rep 1985;69:115-17 (Pubitemid 15197088)
-
(1985)
Cancer Treatment Reports
, vol.69
, Issue.1
, pp. 115-117
-
-
Marti, C.1
Kroner, T.2
Remagen, W.3
-
34
-
-
0023555424
-
Ifosfamide with mesna uroprotection and etoposide: An effective regimen in the treatment of recurrent sarcomas and other tumors of children and young adults
-
Miser JS, Kinsella TJ, Triche TJ, et al. Ifosfamide with mesna uroprotection and etoposide: an effective regimen in the treatment of recurrent sarcomas and other tumors of children and young adults. J Clin Oncol 1987;5:1191-8 (Pubitemid 18045304)
-
(1987)
Journal of Clinical Oncology
, vol.5
, Issue.8
, pp. 1191-1198
-
-
Miser, J.S.1
Kinsella, T.J.2
Triche, T.J.3
Tsokos, M.4
Jarosinski, P.5
Forquer, R.6
Wesley, R.7
Magrath, I.8
-
35
-
-
0023092830
-
Phase II trial of ifosfamide in children with malignant solid tumors
-
Pratt CB, Horowitz ME, Meyer WH, et al. Phase II trial of ifosfamide in children with malignant solid tumors. Cancer Treat Rep 1987;71:131-5 (Pubitemid 17030141)
-
(1987)
Cancer Treatment Reports
, vol.71
, Issue.2
, pp. 131-135
-
-
Pratt, C.B.1
Horowitz, M.E.2
Meyer, W.H.3
-
36
-
-
0023555424
-
Ifosfamide with mesna uroprotection and etoposide: An effective regimen in the treatment of recurrent sarcomas and other tumors of children and young adults
-
Miser JS, Kinsella TJ, Triche TJ, et al. Ifosfamide with mesna uroprotection and etoposide: an effective regimen in the treatment of recurrent sarcomas and other tumors of children and young adults. J Clin Oncol 1987;5:1191-8 (Pubitemid 18045304)
-
(1987)
Journal of Clinical Oncology
, vol.5
, Issue.8
, pp. 1191-1198
-
-
Miser, J.S.1
Kinsella, T.J.2
Triche, T.J.3
Tsokos, M.4
Jarosinski, P.5
Forquer, R.6
Wesley, R.7
Magrath, I.8
-
37
-
-
0034671416
-
Long-term outcome for patients with nonmetastatic osteosarcoma of the extremity treated at the Istituto Ortopedico Rizzoli according to the Istituto Ortopedico Rizzoli/osteosarcoma-2 protocol: An updated report
-
Bacci G, Ferrari S, Bertoni F, et al. Long-term outcome for patients with nonmetastatic osteosarcoma of the extremity treated at the Istituto Orthopedico Rizzoli according to the Istituto Orthopedico Rizzoli/Osteosarcoma-2 protocol: an updated report. J Clin Oncol 2000;18:4016-27 (Pubitemid 32038393)
-
(2000)
Journal of Clinical Oncology
, vol.18
, Issue.24
, pp. 4016-4027
-
-
Bacci, G.1
Ferrari, S.2
Bertoni, F.3
Ruggieri, P.4
Picci, P.5
Longhi, A.6
Casadei, R.7
Fabbri, N.8
Forni, C.9
Versari, M.10
Campanacci, M.11
-
38
-
-
0030995153
-
Ifosfamide and etoposide in childhood osteosarcoma. A phase II study of the French Society of Paediatric Oncology
-
Gentet JC, Brunat-Mentigny M, Demaille MC, et al. Ifosfamide and etoposide in childhood osteosarcoma. A phase II study of the French Society of Paediatric Oncology. Eur J Cancer 1997;33:232-7
-
(1997)
Eur J Cancer
, vol.33
, pp. 232-237
-
-
Gentet, J.C.1
Brunat-Mentigny, M.2
Demaille, M.C.3
-
39
-
-
13444253743
-
High-dose ifosfamide in relapsed pediatric osteosarcoma: Therapeutic effects and renal toxicity
-
DOI 10.1002/pbc.20228
-
Berrak SG, Pearson M, Berberoglu S, et al. High-dose ifosfamide in relapsed pediatric osteosarcoma: therapeutic effects and renal toxicity. Pediatr Blood Cancer 2005;44:215-19 (Pubitemid 40209429)
-
(2005)
Pediatric Blood and Cancer
, vol.44
, Issue.3
, pp. 215-219
-
-
Berrak, S.G.1
Pearson, M.2
Berberoglu, S.3
Ilhan, I.E.4
Jaffe, N.5
-
40
-
-
33947710840
-
SFOP OS94: A randomised trial comparing preoperative high-dose methotrexate plus doxorubicin to high-dose methotrexate plus etoposide and ifosfamide in osteosarcoma patients
-
An important study showing that IFO + VP-16 chemotherapy is effective for osteosarcoma
-
Le Deley MC, Guinebretière JM, Gentet JC, et al. SFOP OS94: a randomised trial comparing preoperative high-dose methotrexate plus doxorubicin to high-dose methotrexate plus etoposide and ifosfamide in osteosarcoma patients. Eur J Cancer 2007;43:752-61 . An important study showing that IFO + VP-16 chemotherapy is effective for osteosarcoma.
-
(2007)
Eur J Cancer
, vol.43
, pp. 752-761
-
-
Le Deley, M.C.1
Guinebretière, J.M.2
Gentet, J.C.3
-
41
-
-
0028948514
-
Treatment of osteosarcoma with ifosfamide: Comparison of response in pediatric patients with recurrent disease versus patients previously untreated: A Pediatric Oncology Group study
-
Harris MB, Cantor AB, Goorin AM, et al. Treatment of osteosarcoma with ifosfamide: comparison of response in pediatric patients with recurrent disease versus patients previously untreated: a Pediatric Oncology Group study. Med Pediatr Oncol 1995;24:87-92
-
(1995)
Med Pediatr Oncol
, vol.24
, pp. 87-92
-
-
Harris, M.B.1
Cantor, A.B.2
Goorin, A.M.3
-
42
-
-
0037080289
-
Phase II/III trial of etoposide and high-dose ifosfamide in newly diagnosed metastatic osteosarcoma: A pediatric oncology group trial
-
DOI 10.1200/JCO.20.2.426
-
Goorin AM, Harris MB, Bernstein M, et al. Phase II/III trial of etoposide and high-dose ifosfamide in newly diagnosed metastatic osteosarcoma: a pediatric oncology group trial. J Clin Oncol 2002;20:426-33 (Pubitemid 34072525)
-
(2002)
Journal of Clinical Oncology
, vol.20
, Issue.2
, pp. 426-433
-
-
Goorin, A.M.1
Harris, M.B.2
Bernstein, M.3
Ferguson, W.4
Devidas, M.5
Siegal, G.P.6
Gebhardt, M.C.7
Schwartz, C.L.8
Link, M.9
Grier, H.E.10
-
43
-
-
33644837672
-
Neoadjuvant chemotherapy with high-dose ifosfamide, high-dose methotrexate, cisplatin, and doxorubicin for patients with localized osteosarcoma of the extremity: A joint study by the italian and Scandinavian Sarcoma Groups
-
DOI 10.1200/JCO.2004.00.5785
-
Ferrari S, Smeland S, Mercuri M, et al. Neoadjuvant chemotherapy with high-dose ifosfamide, high-dose methotrexate, cisplatin, and doxorubicin for patients with localized osteosarcoma of the extremity: a joint study by the Italian and Scandinavian Sarcoma groups. J Clin Oncol 2005;23:8845-52 (Pubitemid 46211531)
-
(2005)
Journal of Clinical Oncology
, vol.23
, Issue.34
, pp. 8845-8852
-
-
Ferrari, S.1
Smeland, S.2
Mercuri, M.3
Bertoni, F.4
Longhi, A.5
Ruggieri, P.6
Alvegard, T.A.7
Picci, P.8
Capanna, R.9
Bernini, G.10
Muller, C.11
Tienghi, A.12
Wiebe, T.13
Comandone, A.14
Bohling, T.15
Del Prever, A.B.16
Brosjo, O.17
Bacci, G.18
Saeter, G.19
-
44
-
-
68849109737
-
Multiinstitutional phase II study of neoadjuvant chemotherapy for osteosarcoma (NECO study) in Japan: NECO-93J and NECO-95J
-
Iwamoto Y, Tanaka K, Isu K, et al. Multiinstitutional phase II study of neoadjuvant chemotherapy for osteosarcoma (NECO study) in Japan: NECO-93J and NECO-95J. J Orthop Sci 2009;14:397-404
-
(2009)
J Orthop Sci
, vol.14
, pp. 397-404
-
-
Iwamoto, Y.1
Tanaka, K.2
Isu, K.3
-
45
-
-
84885603776
-
-
EURAMOS-1 study: recruitment, characteristics and initial treatment of 2000 patients with high-grade osteosarcoma, Available from [Access 25 April 2013]
-
EURAMOS-1 study: recruitment, characteristics and initial treatment of 2000 patients with high-grade osteosarcoma. Available from: http://www.ctu.mrc. ac.uk/euramos/main-site-contentpages/images-and-documents/ASCO%202012/ EURAMOS%20ASCO%202012% 20poster-final.pdf [Access 25 April 2013] . An important study that is the largest multicentre randomised prospective trial for osteosarcoma to date.
-
An Important Study That Is the Largest Multicentre Randomised Prospective Trial for Osteosarcoma to Date
-
-
-
46
-
-
78650687502
-
Phase II study of gemcitabine with oxapiplatin in relapsed or refractory paediatric solid malignancies: An innovative therapy for children with Cancer European Consortium Study
-
Geoerger B, Chisholm J, Le Deley MC, et al. Phase II study of gemcitabine with oxapiplatin in relapsed or refractory paediatric solid malignancies: an innovative therapy for children with Cancer European Consortium Study. Eur J Cancer 2011;37:230-8
-
(2011)
Eur J Cancer
, vol.37
, pp. 230-238
-
-
Geoerger, B.1
Chisholm, J.2
Le Deley, M.C.3
-
47
-
-
84857062135
-
A phase II trial of second-line pemetrexed in adult with advanced/metastatic osteosarcoma
-
Duffaud F, Egerer G, Ferrari S, et al. A phase II trial of second-line pemetrexed in adult with advanced/metastatic osteosarcoma. Eur J Cancer 2012;48:564-70
-
(2012)
Eur J Cancer
, vol.48
, pp. 564-570
-
-
Duffaud, F.1
Egerer, G.2
Ferrari, S.3
-
48
-
-
84864044404
-
Phase II trial of trastuzumab in combination with cytotoxic chemotherapy for treatment of metastatic osteosarcoma with human epidermal growth factor receptor 2 overexpression: A report from the children's oncology group
-
Ebb D, Meyers P, Grier H, et al. Phase II trial of trastuzumab in combination with cytotoxic chemotherapy for treatment of metastatic osteosarcoma with human epidermal growth factor receptor 2 overexpression: a report from the children's oncology group. J Clin Oncol 2012;30:2545-51
-
(2012)
J Clin Oncol
, vol.30
, pp. 2545-2551
-
-
Ebb, D.1
Meyers, P.2
Grier, H.3
-
49
-
-
84862907964
-
Phase I/II trial and pharmacokinetic study of cixutumumab in pediatric patients with refractory solid tumors and Ewing sarcoma: A report from the Children's Oncology Group
-
Malempati S, Weigel B, Ingle AM, et al. Phase I/II trial and pharmacokinetic study of cixutumumab in pediatric patients with refractory solid tumors and Ewing sarcoma: a report from the Children's Oncology Group. J Clin Oncol 2012;30:256-62
-
(2012)
J Clin Oncol
, vol.30
, pp. 256-262
-
-
Malempati, S.1
Weigel, B.2
Ingle, A.M.3
-
50
-
-
84879570162
-
Comprehensive analysis of published phase I/II clinical trials between 1990-2010 in osteosarcoma and Ewing sarcoma confirms limited outcomes and need fortranslational investment
-
van Maldegem AM, Bhosale A, Gelderblom HJ, et al. Comprehensive analysis of published phase I/II clinical trials between 1990-2010 in osteosarcoma and Ewing sarcoma confirms limited outcomes and need fortranslational investment. Clin Sarcoma Res 2012;2:5
-
(2012)
Clin Sarcoma Res
, vol.2
, pp. 5
-
-
Van Maldegem, A.M.1
Bhosale, A.2
Gelderblom, H.J.3
-
51
-
-
0031922848
-
Caffeine-assisted chemotherapy and minimized tumor excision for nonmetastatic osteosarcoma
-
Tsuchiya H, Tomita K, Mori Y, et al. Caffeine-assisted chemotherapy and minimized tumor excision for nonmetastatic osteosarcoma. Anticancer Res 1998;18:657-66 . An important study indicating the capability of enhancers of anticancer drugs to achieve better clinical outcomes. (Pubitemid 28174888)
-
(1998)
Anticancer Research
, vol.18
, Issue.1
, pp. 657-666
-
-
Tsuchiya, H.1
Tomita, K.2
Mori, Y.3
Asada, N.4
Morinaga, T.5
Kitano, S.6
Yamamoto, N.7
-
52
-
-
84885585662
-
Clinical observations of caffeine-potentiated chemotherapy
-
Yamamoto N, Tsuchiya H. Clinical observations of caffeine-potentiated chemotherapy. J Caffeine Res 2011;1:163-8
-
(2011)
J Caffeine Res
, vol.1
, pp. 163-168
-
-
Yamamoto, N.1
Tsuchiya, H.2
-
53
-
-
0024803687
-
Caffeine enhancement of the effect of anticancer agents on human sarcoma cells
-
Tomita K, Tsuchiya H. Caffeine enhancement of the effect of anticancer agents on human sarcoma cells. Jpn J Cancer Res 1989;80:83-8 (Pubitemid 20027203)
-
(1989)
Japanese Journal of Cancer Research
, vol.80
, Issue.1
, pp. 83-88
-
-
Tomita, K.1
Tsuchiya, H.2
-
54
-
-
0024558364
-
Enhancement of cytocidal and antitumor effect of cisplatin by caffeine in human osteosarcoma
-
Tomita K, Tsuchiya H. Enhancement of cytocidal and antitumor effect of cisplatin, by caffeine in human osteosarcoma. Clin Ther 1989;11:43-52 (Pubitemid 19112875)
-
(1989)
Clinical Therapeutics
, vol.11
, Issue.1
, pp. 43-52
-
-
Tomita, K.1
Tsuchiya, H.2
-
55
-
-
0024843463
-
Growth inhibition and differentiation of murine melanoma B16-BL6 cells caused by the combination of cisplatin and caffeine
-
Tsuchiya H, Tomita K, Yasutake H, et al. Growth inhibition and differentiation of murine melanoma B16-BL6 cells caused by the combination of cisplatin and caffeine. Jpn J Cancer Res 1989;80:1246-51 (Pubitemid 20050995)
-
(1989)
Japanese Journal of Cancer Research
, vol.80
, Issue.12
, pp. 1246-1251
-
-
Tsuchiya, H.1
Tomati, K.2
Yasutake, H.3
Ueda, Y.4
Tanaka, M.5
Sasaki, T.6
-
56
-
-
0022365834
-
Enhanced therapeutic effect of cis-diamminedichloroplatinum(II) against nude mouse grown human pancreatic adenocarcinoma when combined with 1-β-D-arabinofuranosylcytosine and caffeine
-
Kyriazis AP, Kyriazis AA, Yagoda A. Enhanced therapeutic effect of cisdiamminedichloroplatinum( II) against nude mouse grown human pancreatic adenocarcinoma when combined with 1-beta-D-arabinofuranosylcytosine and caffeine. Cancer Res 1985;45:6083-7 (Pubitemid 16224763)
-
(1985)
Cancer Research
, vol.45
, Issue.12
, pp. 6083-6087
-
-
Kyriazis, A.1
Kyriazis, A.A.2
Yagoda, A.3
-
57
-
-
0028289752
-
Greater enhancement of chemosensitivity by caffeine in high-p185neu-expressing human non-small-cell lung cancer cell lines
-
Tsai CM, Perng RP, Chen MH, et al. Greater enhancement of chemosensitivity by caffeine in high-p185neu-expressing human non-small-cell lung cancer cell lines. J Natl Cancer inst 1994;86:1018-20
-
(1994)
J Natl Cancer Inst
, vol.86
, pp. 1018-1020
-
-
Tsai, C.M.1
Perng, R.P.2
Chen, M.H.3
-
58
-
-
0031449479
-
In vitro enhancement of antitumor activity of a water-soluble duocarmycin derivative, KW-2189, by caffeine-mediated DNA-repair inhibition in human lung cancer cells
-
Ogasawara H, Nishio K, Ishida T, et al. In vitro enhancement of antitumor activity of a water-soluble duocarmycin derivative, KW-2189, by caffeine-mediated DNA-repair inhibition in human lung cancer cells. Jpn J Cancer Res 1997;88:1033-7 (Pubitemid 28021474)
-
(1997)
Japanese Journal of Cancer Research
, vol.88
, Issue.11
, pp. 1033-1037
-
-
Ogasawara, H.1
Nishio, K.2
Ishida, T.3
Arioka, H.4
Fukuoka, K.5
Saijo, N.6
-
59
-
-
0032566339
-
Caffeine and staurosporine enhance the cytotoxicity of cisplatin and camptothecin in human brain tumor cell lines
-
DOI 10.1006/excr.1998.4122
-
Janss AJ, Levow C, Bernhand EJ, et al. Caffeine and staurosporine enhance the cytotoxicity of cisplatin and camptothecin in human brain tumor cell lines. Exp cell Res 1998;243:29-38 (Pubitemid 28397631)
-
(1998)
Experimental Cell Research
, vol.243
, Issue.1
, pp. 29-38
-
-
Janss, A.J.1
Levow, C.2
Bernhard, E.J.3
Muschel, R.J.4
McKenna, W.G.5
Sutton, L.6
Phillips, P.C.7
-
60
-
-
0032442707
-
Combined effect of CDDP and caffeine against human gastric cell line in vivo
-
Takahashi M, Yanoma S, Yamamoto Y, et al. Combined effect of CDDP and caffeine against human gastric cell line in vivo. Anticancer Res 1998;18:4399-401 (Pubitemid 29043666)
-
(1998)
Anticancer Research
, vol.18
, Issue.6
, pp. 4399-4401
-
-
Takahashi, M.1
Yanoma, S.2
Yamamotq, Y.3
Rino, Y.4
Amano, T.5
Imada, T.6
-
61
-
-
77953666099
-
Current concepts on the molecular biology of osteosarcoma
-
Gorlick R. Current concepts on the molecular biology of osteosarcoma. Cancer Treat Res 2009;152:467-78
-
(2009)
Cancer Treat Res
, vol.152
, pp. 467-478
-
-
Gorlick, R.1
-
62
-
-
79955524738
-
Molecular alterations as target for therapy in metastatic osteosarcoma: A review of literature
-
An important review that explains the molecular alterations in metastatic osteosarcoma and introduces (pre)clinical studies in this field
-
PosthumaDeBoer J, Witlox MA, Kaspers GJ, et al. Molecular alterations as target for therapy in metastatic osteosarcoma: a review of literature. Clin Exp Metastasis 2011;28:493-503 . An important review that explains the molecular alterations in metastatic osteosarcoma and introduces (pre)clinical studies in this field.
-
(2011)
Clin Exp Metastasis
, vol.28
, pp. 493-503
-
-
Posthumadeboer, J.1
Witlox, M.A.2
Kaspers, G.J.3
-
63
-
-
0030844897
-
Phase II study of recombinant interleukin 1α and etoposide in patients with relapsed osteosarcoma
-
Worth LL, Jaffe N, Benjamin RS, et al. Phase II study of recombinant interleukin 1alpha and etoposide in patients with relapsed osteosarcoma. Clin Cancer Res 1997;3:1721-9 (Pubitemid 27444710)
-
(1997)
Clinical Cancer Research
, vol.3
, Issue.10
, pp. 1721-1729
-
-
Worth, L.L.1
Jaffe, N.2
Benjamin, R.S.3
Papadopoulos, N.E.4
Patel, S.5
Raymond, A.K.6
Jia, S.-F.7
Rodriguez, C.8
Gano, J.9
Gianan, M.A.10
Kleinerman, E.S.11
-
64
-
-
0036694322
-
Treatment of metastatic osteosarcoma with the somatostatin analog OncoLar: Significant reduction of insulin-like growth factor-1 serum levels
-
Mansky PJ, Liewehr DJ, Steinberg SM, et al. Treatment of metastatic osteosarcoma with the somatostatin analog OncoLar: significant reduction of insulin-like growth factor-1 serum levels. J Pediatr Hematol Oncol 2002;24:440-6
-
(2002)
J Pediatr Hematol Oncol
, vol.24
, pp. 440-446
-
-
Mansky, P.J.1
Liewehr, D.J.2
Steinberg, S.M.3
-
65
-
-
24944519394
-
Phase i and pharmacokinetic study of gefitinib in children with refractory solid tumors: A Children's Oncology Group Study
-
Daw NC, Furman WL, Stewart CF, et al. Phase I and pharmacokinetic study of gefitinib in children with refractory solid tumors: a Children's Oncology Group Study. J Clin Oncol 2005;23:6172-80
-
(2005)
J Clin Oncol
, vol.23
, pp. 6172-6180
-
-
Daw, N.C.1
Furman, W.L.2
Stewart, C.F.3
-
66
-
-
15744364211
-
A multicenter phase II study of bortezomib in ecurrent or metastatic sarcomas
-
DOI 10.1002/cncr.20968
-
Maki RG, Kraft AS, Scheu K, et al. A multicenter phase II study of bortezomib in recurrent or metastatic sarcomas. Cancer 2005;103:1431-8 (Pubitemid 40410740)
-
(2005)
Cancer
, vol.103
, Issue.7
, pp. 1431-1438
-
-
Maki, R.G.1
Kraft, A.S.2
Scheu, K.3
Yamada, J.4
Wadler, S.5
Antonescu, C.R.6
Wright, J.J.7
Schwartz, G.K.8
-
67
-
-
34547788184
-
Analysis of biologic surrogate markers from a children's oncology group phase I trial of gefitinib in pediatric patients with solid tumors
-
DOI 10.1002/pbc.20753
-
Jimeno A, Daw NC, Amador ML, et al. Analysis of biologic surrogate markers from a Children's Oncology Group Phase I trial of gefitinib in pediatric patients with solid tumors. Pediatric Blood Cancer 2007;49:352-7 (Pubitemid 47236232)
-
(2007)
Pediatric Blood and Cancer
, vol.49
, Issue.3
, pp. 352-357
-
-
Jimeno, A.1
Daw, N.C.2
Amador, M.L.3
Cusatis, G.4
Kulesza, P.5
Krailo, M.6
Ingle, A.M.7
Blaney, S.M.8
Adamson, P.9
Hidalgo, M.10
-
68
-
-
36849018928
-
Phase I study of targeted radioimmunotherapy for leptomeningeal cancers using intra-Ommaya 131-I-3F8
-
DOI 10.1200/JCO.2007.11.1807
-
Kramer K, Humm JL, Souweidane MM, et al. Phase I study of targeted radioimmunotherapy for leptomeningeal cancers using intra-Ommaya 131-I-3F8. J Clin Oncol 2007;25:5465-70 (Pubitemid 350232224)
-
(2007)
Journal of Clinical Oncology
, vol.25
, Issue.34
, pp. 5465-5470
-
-
Kramer, K.1
Humm, J.L.2
Souweidane, M.M.3
Zanzonico, P.B.4
Dunkel, I.J.5
Gerald, W.L.6
Khakoo, Y.7
Yeh, S.D.8
Yeung, H.W.9
Finn, R.D.10
Wolden, S.L.11
Larson, S.M.12
Cheung, N.-K.V.13
-
69
-
-
37549041711
-
A phase II study of imatinib mesylate in children with refractory or relapsed solid tumors: A Children's Oncology Group study
-
Bond M, Bernstein ML, Pappo A, et al. A phase II study of imatinib mesylate in children with refractory or relapsed solid tumors: a Children's Oncology Group study. Pediatric Blood Cancer 2008;50:254-8
-
(2008)
Pediatric Blood Cancer
, vol.50
, pp. 254-258
-
-
Bond, M.1
Bernstein, M.L.2
Pappo, A.3
-
70
-
-
54449085941
-
Pediatric phase i and pharmacokinetic study of erlotinib followed by the combination of erlotinib and temozolomide: A Children's Oncology Group Phase i Consortium Study
-
Jakacki RI, Hamilton M, Gilbertson RJ, et al. Pediatric phase I and pharmacokinetic study of erlotinib followed by the combination of erlotinib and temozolomide: a Children's Oncology Group Phase I Consortium Study. J Clin Oncol 2008;26:4921-7
-
(2008)
J Clin Oncol
, vol.26
, pp. 4921-4927
-
-
Jakacki, R.I.1
Hamilton, M.2
Gilbertson, R.J.3
-
71
-
-
69949145988
-
Phase I/II and phase II studies of targeted gene delivery in vivo: Intravenous Rexin-G for chemotherapy-resistant sarcoma and osteosarcoma
-
Chawla SP, Chua VS, Fernandez L, et al. Phase I/II and phase II studies of targeted gene delivery in vivo: intravenous Rexin-G for chemotherapy- resistant sarcoma and osteosarcoma. Mol Ther 2009;17:1651-7
-
(2009)
Mol Ther
, vol.17
, pp. 1651-1657
-
-
Chawla, S.P.1
Chua, V.S.2
Fernandez, L.3
-
72
-
-
67650302850
-
Phase II multicenter trial of imatinib in 10 histologic subtypes of sarcoma using a Bayesian hierarchical statistical model
-
Chugh R, Wathen JK, Maki RG, et al. Phase II multicenter trial of imatinib in 10 histologic subtypes of sarcoma using a Bayesian hierarchical statistical model. J Clin Oncol 2009;27:3148-53
-
(2009)
J Clin Oncol
, vol.27
, pp. 3148-3153
-
-
Chugh, R.1
Wathen, J.K.2
Maki, R.G.3
-
73
-
-
84875158718
-
Results of a Sarcoma Alliance for Research through Collaboration (SARC) phase II trial of dasatinib in previously treated, high-grade, advanced sarcoma
-
Schuetze S, Wathen K, Choy E, et al. Results of a Sarcoma Alliance for Research through Collaboration (SARC) phase II trial of dasatinib in previously treated, high-grade, advanced sarcoma. J Clin Oncol 2010;28:10009
-
(2010)
J Clin Oncol
, vol.28
, pp. 10009
-
-
Schuetze, S.1
Wathen, K.2
Choy, E.3
-
74
-
-
84867574623
-
Insulin-like growth factor type 1 receptor (IGF-1R) exclusive nuclear staining: A predictive biomarker for IGF-1R monoclonal antibody (Ab) therapy in sarcomas
-
Asmane I, Watkin E, Alberti L, et al. Insulin-like growth factor type 1 receptor (IGF-1R) exclusive nuclear staining: a predictive biomarker for IGF-1R monoclonal antibody (Ab) therapy in sarcomas. Eur J Cancer 2012;48:3027-35
-
(2012)
Eur J Cancer
, vol.48
, pp. 3027-3035
-
-
Asmane, I.1
Watkin, E.2
Alberti, L.3
-
75
-
-
69949145988
-
Phase I/II and phase II studies of targeted gene delivery in vivo: Intravenous Rexin-G for chemotherapy-resistant sarcoma and osteosarcoma
-
A landmark study that was the first Phase II trial of a gene therapy for osteosarcoma
-
Chawla SP, Chua VS, Fernandez L, et al. Phase I/II and phase II studies of targeted gene delivery in vivo: intravenous Rexin-G for chemotherapy- resistant sarcoma and osteosarcoma. Mol Ther 2009;17:1651-7 .. A landmark study that was the first Phase II trial of a gene therapy for osteosarcoma.
-
(2009)
Mol Ther
, vol.17
, pp. 1651-1657
-
-
Chawla, S.P.1
Chua, V.S.2
Fernandez, L.3
-
76
-
-
34447535345
-
Engineering targeted viral vectors for gene therapy
-
DOI 10.1038/nrg2141, PII NRG2141
-
Waehler R, Russell SJ, Curiel DT. Engineering targeted viral vectors for gene therapy. Nat Rev Genet 2007;8:573-87 (Pubitemid 47077278)
-
(2007)
Nature Reviews Genetics
, vol.8
, Issue.8
, pp. 573-587
-
-
Waehler, R.1
Russell, S.J.2
Curiel, D.T.3
-
77
-
-
0034192369
-
Molecular engineering of matrix-targeted retroviral vectors incorporating a surveillance function inherent in von willebrand factor
-
DOI 10.1089/10430340050015293
-
Hall FL, Liu L, Zhu NL, et al. Molecular engineering of matrix-targeted retroviral vectors incorporating a surveillance function inherent in von Willebrand factor. Hum Gene Ther 2000;11:983-93 (Pubitemid 30250115)
-
(2000)
Human Gene Therapy
, vol.11
, Issue.7
, pp. 983-993
-
-
Hall, F.L.1
Liu, L.2
Zhu, N.L.3
Stapfer, M.4
Anderson, W.F.5
Beart, R.W.6
Gordon, E.M.7
-
78
-
-
0035409211
-
Long term inhibition of neointima formation in balloon-injured rat arteries by intraluminal instillation of a matrix-targeted retroviral vector bearing a cytocidal mutant cyclin G1 construct
-
Xu F, Prescott MF, Liu PX, et al. Long term inhibition of neointima formation in balloon-injured rat arteries by intraluminal instillation of a matrix-targeted retroviral vector bearing a cytocidal mutant cyclin G1 construct. Int J Mol Med 2001;8:19-30
-
(2001)
Int J Mol Med
, vol.8
, pp. 19-30
-
-
Xu, F.1
Prescott, M.F.2
Liu, P.X.3
-
79
-
-
0028840423
-
Retroviral vector-mediated gene transfer of antisense cyclin G1 (CYCG1) inhibits proliferation of human osteogenic sarcoma cells
-
Skotzko M, Wu L, Anderson WF, et al. Retroviral vector-mediated gene transfer of antisense cyclin G1 (CYCG1) inhibits proliferation of human osteogenic sarcoma cells. Cancer Res 1995;55:5493-8
-
(1995)
Cancer Res
, vol.55
, pp. 5493-5498
-
-
Skotzko, M.1
Wu, L.2
Anderson, W.F.3
-
80
-
-
77951123789
-
Rexin-G, a targeted genetic medicine for cancer
-
Gordon EM, Hall FL. Rexin-G, a targeted genetic medicine for cancer. Expert Opin Biol Ther 2010;10:819-32
-
(2010)
Expert Opin Biol Ther
, vol.10
, pp. 819-832
-
-
Gordon, E.M.1
Hall, F.L.2
-
81
-
-
0034616329
-
2/M DNA damage checkpoint by inhibiting ataxia-telangiectasia-mutated kinase activity
-
DOI 10.1074/jbc.275.14.10342
-
Zhou BB, Chaturvedi P, Spring K, et al. Caffeine abolishes the mammalian G(2)/M DNA damage checkpoint by inhibiting ataxia-telangiectasia-mutated kinase activity. J Biol Chem 2000;275:10342-8 (Pubitemid 30202093)
-
(2000)
Journal of Biological Chemistry
, vol.275
, Issue.14
, pp. 10342-10348
-
-
Zhou, B.-B.S.1
Chaturvedi, P.2
Spring, K.3
Scott, S.P.4
Johanson, R.A.5
Mishra, R.6
Mattern, M.R.7
Winkler, J.D.8
Khanna, K.K.9
-
82
-
-
0033199892
-
Inhibition of ATM and ATR kinase activities by the radiosensitizing agent, caffeine
-
Sarkaria JN, Busby EC, Tibbetts RS, et al. Inhibition of ATM and ATR kinase activities by the radiosensitizing agent, caffeine. Cancer Res 1999;59:4375-82 (Pubitemid 29418757)
-
(1999)
Cancer Research
, vol.59
, Issue.17
, pp. 4375-4382
-
-
Sarkaria, J.N.1
Busby, E.C.2
Tibbetts, R.S.3
Roos, P.4
Taya, Y.5
Karnitz, L.M.6
Abraham, R.T.7
-
83
-
-
0033555260
-
A role for ATR in the DNA damage-induced phosphorylation of p53
-
Tibbetts RS, Brumbaugh KM, Williams JM, et al. A role for ATR in the DNA damage-induced phosphorylation of p53. Genes Dev 1999;13:152-7 (Pubitemid 29061945)
-
(1999)
Genes and Development
, vol.13
, Issue.2
, pp. 152-157
-
-
Tibbetts, R.S.1
Brumbaugh, K.M.2
Williams, J.M.3
Sarkaria, J.N.4
Cliby, W.A.5
Shieh, S.-Y.6
Taya, Y.7
Prives, C.8
Abraham, R.T.9
-
84
-
-
0042591432
-
Induction of apoptosis by caffeine is mediated by the p53, Bax, and caspase 3 pathways
-
He Z, Ma WY, Hashimoto T, et al. Induction of apoptosis by caffeine is mediated by the p53, Bax, and caspase 3 pathways. Cancer Res 2003;63:4396-401 (Pubitemid 36951009)
-
(2003)
Cancer Research
, vol.63
, Issue.15
, pp. 4396-4401
-
-
He, Z.1
Ma, W.-Y.2
Hashimoto, T.3
Bode, A.M.4
Yang, C.S.5
Dong, Z.6
-
85
-
-
0025236932
-
Preoperative chemotherapy for soft-tissue sarcomas of the extremities
-
Pezzi CM, Pollock RE, Evans HL, et al. Preoperative chemotherapy for soft-tissue sarcomas of the extremities. Ann Surg 1990;211:476-81 (Pubitemid 20138190)
-
(1990)
Annals of Surgery
, vol.211
, Issue.4
, pp. 476-481
-
-
Pezzi, C.M.1
Pollock, R.E.2
Evans, H.L.3
Lorigan, J.G.4
Pezzi, T.A.5
Benjamin, R.S.6
Romsdahl, M.M.7
-
86
-
-
0030699251
-
Preoperative chemotherapy for stage IIIB extremity soft tissue sarcoma: Long-term results from a single institution
-
Pisters PW, Patel SR, Varma DG, et al. Preoperative chemotherapy for stage IIIB extremity soft tissue sarcoma: long-term results from a single institution. J Clin Oncol 1997;15:3481-7 (Pubitemid 27527721)
-
(1997)
Journal of Clinical Oncology
, vol.15
, Issue.12
, pp. 3481-3487
-
-
Pisters, P.W.T.1
Patel, S.R.2
Varma, D.G.K.3
Cheng, S.-C.4
Chen, N.P.5
Nguyen, H.T.B.6
Feig, B.W.7
Pollack, A.8
Pollock, R.E.9
Benjamin, R.S.10
-
87
-
-
0036720472
-
Radiographic response to neoadjuvant chemotherapy is a predictor of local control and survival in soft tissue sarcomas
-
DOI 10.1002/cncr.10794
-
Meric F, Hess KR, Varma DG, et al. Radiographic response to neoadjuvant chemotherapy is a predictor of local control and survival in soft tissue sarcomas. Cancer 2002;95:1120-6 (Pubitemid 34925365)
-
(2002)
Cancer
, vol.95
, Issue.5
, pp. 1120-1126
-
-
Meric, F.1
Hess, K.R.2
Varma, D.G.K.3
Hunt, K.K.4
Pisters, P.W.T.5
Milas, K.M.6
Patel, S.R.7
Benjamin, R.S.8
Plager, C.9
Papadopoulos, N.E.J.10
Burgess, M.A.11
Pollock, R.E.12
Feig, B.W.13
-
88
-
-
0035003544
-
A randomised phase II study on neo-adjuvant chemotherapy for 'high-risk' adult soft-tissue sarcoma
-
Gortzak E, Azzarelli A, Buesa J, et al. A randomised phase II study on neo-adjuvant chemotherapy for 'high-risk' adult soft-tissue sarcoma. Eur J Cancer 2001;37:1096-103
-
(2001)
Eur J Cancer
, vol.37
, pp. 1096-1103
-
-
Gortzak, E.1
Azzarelli, A.2
Buesa, J.3
-
89
-
-
0035399207
-
Treatment-induced pathologic necrosis: A predictor of local recurrence and survival in patients receiving neoadjuvant therapy for high-grade extremity soft tissue sarcomas
-
Eilber FC, Rosen G, Eckardt J, et al. Treatment-induced pathologic necrosis: a predictor of local recurrence and survival in patients receiving neoadjuvant therapy for high-grade extremity soft tissue sarcomas. J Clin Oncol 2001;19:3203-9 (Pubitemid 32591437)
-
(2001)
Journal of Clinical Oncology
, vol.19
, Issue.13
, pp. 3203-3209
-
-
Eilber, F.C.1
Rosen, G.2
Eckardt, J.3
Forscher, C.4
Nelson, S.D.5
Selch, M.6
Dorey, F.7
Eilber, F.R.8
-
90
-
-
35348965187
-
Caffeine-potentiated chemotherapy for patients with high-grade soft tissue sarcoma: Long-term clinical outcome
-
Takeuchi A, Tsuchiya H, Yamamoto N, et al. Caffeine-potentiated chemotherapy for patients with high-grade soft tissue sarcoma: long-term clinical outcome. Anticancer Res 2007;27:3489-96
-
(2007)
Anticancer Res
, vol.27
, pp. 3489-3496
-
-
Takeuchi, A.1
Tsuchiya, H.2
Yamamoto, N.3
-
91
-
-
22944448045
-
Caffeine-potentiated chemotherapy for metastatic carcinoma and lymphoma of bone and soft tissue
-
Hayashi M, Tsuchiya H, Yamamoto N, et al. Caffeine-potentiated chemotherapy for metastatic carcinoma and lymphoma of bone and soft tissue. Anticancer Res 2005;25:2399-405 (Pubitemid 41044722)
-
(2005)
Anticancer Research
, vol.25
, Issue.3
, pp. 2399-2405
-
-
Hayashi, M.1
Tsuchiya, H.2
Yamamoto, N.3
Karita, M.4
Shirai, T.5
Nishida, H.6
Takeuchi, A.7
Tomita, K.8
-
92
-
-
0018839580
-
Randomized trial of chlorpromazine, caffeine, and methyl-CCNU in disseminated melanoma
-
Cohen M, Schoenfeld D, Wolter J. Randomized trials of chlorpromazine, caffeine, and methyl-CCNU in disseminated melanoma. Cancer Treat Rep 1980;64:151-3 (Pubitemid 10125469)
-
(1980)
Cancer Treatment Reports
, vol.64
, Issue.1
, pp. 151-153
-
-
Cohen, M.H.1
Schoenfeld, D.2
Wolter, J.3
-
93
-
-
0023355696
-
Cytosine arabinoside plus cisplatin and other drugs as chemotherapy for gliomas
-
Stewart DJ, Hugenholtz H, Dasilva V, et al. Cytosine arabinoside plus cisplatin and other drugs as chemotherapy for gliomas. Semin Oncol 1987;14:110-15
-
(1987)
Semin Oncol
, vol.14
, pp. 110-115
-
-
Stewart, D.J.1
Hugenholtz, H.2
Dasilva, V.3
-
94
-
-
0025987989
-
A phase III comparison trial of streptozotocin, mitomycin, and 5-fluorouracil with cisplatin, cytosine arabinoside, and caffeine in patients with advanced pancreatic carcinoma
-
Kelsen D, Hudis C, Niedzwiecki D, et al. A phase III comparison trial of streptozotocin, mitomycin, and 5-fluorouracil with cisplatin, cytosine arabinoside, and caffeine in patients with advanced pancreatic carcinoma. Cancer 1991;68:965-9
-
(1991)
Cancer
, vol.68
, pp. 965-969
-
-
Kelsen, D.1
Hudis, C.2
Niedzwiecki, D.3
-
95
-
-
0346243858
-
Chemoradiotherapy in the Treatment of Regional Pancreatic Carcinoma: A Phase II Study
-
DOI 10.1097/01.coc.0000037143.60502.54
-
Al-Sukhun S, Zalupski MM, Ben-Josef E, et al. Chemoradiotherapy in the treatment of regional pancreatic carcinoma: a phase II study. Am J Clin Oncol 2003;26:543-9 (Pubitemid 37523053)
-
(2003)
American Journal of Clinical Oncology: Cancer Clinical Trials
, vol.26
, Issue.6
, pp. 543-549
-
-
Al-Sukhun, S.1
Zalupski, M.M.2
Ben-Josef, E.3
Vaitkevicius, V.K.4
Philip, P.A.5
Soulen, R.6
Weaver, D.7
Adsay, V.8
Heilbrun, L.K.9
Levin, K.10
Forman, J.D.11
Shields, A.F.12
-
96
-
-
0032899225
-
Marginal excision for osteosarcoma with caffeine assisted chemotherapy
-
Tsuchiya H, Tomita K, Mori Y, et al. Marginal excision for osteosarcoma with caffeine assisted chemotherapy. Clin Orthop Relat Res 1999;358:27-35 (Pubitemid 29066071)
-
(1999)
Clinical Orthopaedics and Related Research
, Issue.358
, pp. 27-35
-
-
Tsuchiya, H.1
Tomita, K.2
Mori, Y.3
Asada, N.4
Yamamoto, N.5
|