Effect of poly(propylene imine) glycodendrimers on β-amyloid aggregation in vitro and in APP/PS1 transgenic mice, as a model of brain amyloid deposition and alzheimer's disease

Biomacromolecules

Volumn 14, Issue 10, 2013, Pages 3570-3580

  Klementieva, O ^a   Aso, E ^a   Filippini, D ^b   Benseny Cases, N ^c   Carmona, M ^a   Juves S ^a   Appelhans, D ^b   Cladera, J ^d   Ferrer, I ^a,e,f  

^a HOSPITAL UNIVERSITARI DE BELLVITGE   (Spain)

^b LEIBNIZ INSTITUTE OF POLYMER RESEARCH DRESDEN   (Germany)

^c EUROPEAN SYNCHROTRON RADIATION FACILITY   (France)

^d UNIVERSITAT AUTÒNOMA DE BARCELONA   (Spain)

^e UNIVERSITY OF BARCELONA   (Spain)

^f INSTITUTO DE SALUD CARLOS III   (Spain)

Author keywords

[No Author keywords available]

Indexed keywords

CYTOLOGY; DENDRIMERS; MALTOSE; MAMMALS; NEURODEGENERATIVE DISEASES; NITROGEN COMPOUNDS; PROPYLENE; TOXICITY;

ALZHEIMER'S DISEASE; AMYLOID DEPOSITION; BLOOD-BRAIN BARRIER; COGNITIVE DECLINE; HARMFUL EFFECTS; NEUROBLASTOMA CELLS; POLY(PROPYLENE IMINE); TRANSGENIC MICE;

GLYCOPROTEINS;

AMYLOID BETA PROTEIN[1-42]; BRAIN EXTRACT; CATION; DENDRIMER; IMINE; MALTOSE; MALTOTRIOSE; POLY(PROPYLENE IMINE) GLYCODENDRIMER; UNCLASSIFIED DRUG; AMYLOID PRECURSOR PROTEIN; GLYCOCONJUGATE; POLY(PROPYLENEIMINE); POLYPROPYLENE; PROTEIN SERINE THREONINE KINASE;

ANIMAL CELL CULTURE; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BRAIN TISSUE; BRAIN TOXICITY; CONTROLLED STUDY; CYTOPLASM; HUMAN; HUMAN CELL; IN VITRO STUDY; IN VIVO STUDY; MALE; MOUSE; NEUROBLASTOMA CELL; NONHUMAN; PRIORITY JOURNAL; PROTEIN AGGREGATION; SURFACE PROPERTY; ALZHEIMER DISEASE; ANIMAL; BRAIN; CELL SURVIVAL; CHEMISTRY; DISEASE MODEL; DOSE RESPONSE; DRUG EFFECTS; GENETICS; INTRANASAL DRUG ADMINISTRATION; METABOLISM; PARTICLE SIZE; PATHOLOGY; STRUCTURE ACTIVITY RELATION; TRANSGENIC MOUSE; TUMOR CELL CULTURE;

MUS; MUS MUSCULUS;

ADMINISTRATION, INTRANASAL; ALZHEIMER DISEASE; AMYLOID BETA-PROTEIN PRECURSOR; ANIMALS; BRAIN; CELL SURVIVAL; DENDRIMERS; DISEASE MODELS, ANIMAL; DOSE-RESPONSE RELATIONSHIP, DRUG; GLYCOCONJUGATES; HUMANS; MALE; MALTOSE; MICE; MICE, TRANSGENIC; PARTICLE SIZE; POLYPROPYLENES; PROTEIN-SERINE-THREONINE KINASES; STRUCTURE-ACTIVITY RELATIONSHIP; SURFACE PROPERTIES; TUMOR CELLS, CULTURED;

EID: 84885605499     PISSN: 15257797     EISSN: 15264602     Source Type: Journal    
DOI: 10.1021/bm400948z     Document Type: Article

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