Lack of CD47 impairs bone cell differentiation and results in an osteopenic phenotype in vivo due to impaired signal regulatory protein α (SIRPα) signaling

Journal of Biological Chemistry

Volumn 288, Issue 41, 2013, Pages 29333-29344

  Koskinen, Cecilia ^a   Persson, Emelie ^a   Baldock, Paul ^b   Stenberg, Åsa ^a   Boström, Ingrid ^a   Matozaki, Takashi ^c   Oldenborg, Per Arne ^a   Lundberg, Pernilla ^a  

^a UMEÅ UNIVERSITY   (Sweden)

^b GARVAN INSTITUTE OF MEDICAL RESEARCH   (Australia)

^c KOBE UNIVERSITY GRADUATE SCHOOL OF MEDICINE   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

BONE CELL DIFFERENTIATION; BONE MARROW STROMAL CELLS; OSTEOBLAST DIFFERENTIATION; OSTEOGENIC DIFFERENTIATION; PARATHYROID HORMONES; SIGNAL REGULATORY PROTEINS; TARTRATE-RESISTANT ACID PHOSPHATASE; TYROSINE PHOSPHORYLATION;

AMINO ACIDS; BIOMATERIALS; BONE; CELL MEMBRANES; CYTOLOGY; GENE EXPRESSION; LIGANDS; MAMMALS; OSTEOBLASTS; PHOSPHATASES; PROTEINS; SIGNALING;

CELL SIGNALING;

ACID PHOSPHATASE TARTRATE RESISTANT ISOENZYME; CD47 ANTIGEN; CELL SURFACE PROTEIN; COLLAGEN; PARATHYROID HORMONE; REGULATOR PROTEIN;

ANIMAL CELL; ANIMAL EXPERIMENT; ARTICLE; BONE MARROW; BONE MARROW CULTURE; CELL DIFFERENTIATION; CONTROLLED STUDY; CYTOPLASM; IN VITRO STUDY; IN VIVO STUDY; MALE; MOUSE; NONHUMAN; OSSIFICATION; OSTEOBLAST; OSTEOCLAST; OSTEOCLASTOGENESIS; OSTEOLYSIS; OSTEOPENIA; PHENOTYPE; PRIORITY JOURNAL; PROTEIN PHOSPHORYLATION;

BONE; CD47; CELL DIFFERENTIATION; OSTEOBLASTS; OSTEOCLAST; SIRPALPHA; STROMAL CELL;

ANIMALS; ANTIGENS, CD47; BLOTTING, WESTERN; BONE AND BONES; BONE DISEASES, METABOLIC; BONE MARROW CELLS; CELL DIFFERENTIATION; CELLS, CULTURED; COCULTURE TECHNIQUES; MICE; MICE, INBRED BALB C; MICE, INBRED C57BL; MICE, KNOCKOUT; MUTATION; MYELOID PROGENITOR CELLS; OSTEOBLASTS; OSTEOCLASTS; OSTEOGENESIS; PHENOTYPE; RECEPTORS, IMMUNOLOGIC; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; SIGNAL TRANSDUCTION; STROMAL CELLS;

EID: 84885591935     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M113.494591     Document Type: Article

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