GWAS to therapy by genome edits?

Science

Volumn 342, Issue 6155, 2013, Pages 206-207

  Hardison, Ross C ^a   Blobel, Gerd A ^b,c  

^a PENNSYLVANIA STATE UNIVERSITY   (United States)

^b CHILDREN S HOSPITAL OF PHILADELPHIA   (United States)

^c UNIVERSITY OF PENNSYLVANIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

HEMOGLOBIN F; TRANSCRIPTION FACTOR; BCL11A PROTEIN, HUMAN; CARRIER PROTEIN; NUCLEAR PROTEIN;

DISEASE TREATMENT; GENETIC ANALYSIS; GENOME; GENOMICS; HEMOGLOBIN;

DISEASE PREDISPOSITION; ERYTHROID CELL; GENE DELETION; GENE EXPRESSION; GENE REPLACEMENT THERAPY; GENE THERAPY; GENETIC ASSOCIATION; GENETIC ENGINEERING AND GENE TECHNOLOGY; GLOBIN GENE; HEMOGLOBINOPATHY; HERITABILITY; HUMAN; HYPERSENSITIVITY; LYMPHOID CELL LINE; NONHUMAN; PHENOTYPE; PRIORITY JOURNAL; QUANTITATIVE TRAIT LOCUS; SHORT SURVEY; SICKLE CELL ANEMIA; SINGLE NUCLEOTIDE POLYMORPHISM; THALASSEMIA; ANIMAL; BIOSYNTHESIS; ENHANCER REGION; GENE EXPRESSION REGULATION; GENETICS; METABOLISM; NOTE;

ANIMALS; CARRIER PROTEINS; ENHANCER ELEMENTS, GENETIC; ERYTHROID CELLS; FETAL HEMOGLOBIN; GENE EXPRESSION REGULATION; HEMOGLOBINOPATHIES; HUMANS; NUCLEAR PROTEINS;

EID: 84885587219     PISSN: 00368075     EISSN: 10959203     Source Type: Journal    
DOI: 10.1126/science.1245813     Document Type: Short Survey

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