Synthesis and oxidant properties of phase 1 benzepine N-oxides of common antipsychotic drugs

Synthesis (Germany)

Volumn 45, Issue 20, 2013, Pages 2875-2887

  Körber, Jochen ^a   Löffler, Stefan ^b   Schollmeyer, Dieter ^a   Nubbemeyer, Udo ^a  

^a JOHANNES GUTENBERG UNIVERSITY   (Germany)

^b SANA KLINIKUM OFFENBACH   (Germany)

Author keywords

benzepines; catalysis; dihydroxylations; drugs; medicinal chemistry; oxidations; transition metals

Indexed keywords

BENZEPINES; CATALYZED OXIDATION; CHEMICAL TRANSFORMATIONS; DIHYDROXYLATIONS; DRUGS; MEDICINAL CHEMISTRY; N-METHYLMORPHOLINE-N-OXIDE; TRANSITION-METAL-CATALYZED REACTIONS;

CATALYSIS; OXIDANTS; OXYGEN; STYRENE; TRANSITION METALS;

OXIDATION;

4 METHYLMORPHOLINE N OXIDE; AMINE OXIDE; BENZEPINE N OXIDE; CLOZAPINE N OXIDE; NEUROLEPTIC AGENT; OLANZAPINE N OXIDE; OSMIUM TETRAOXIDE; OXIDIZING AGENT; OXYGEN; QUETIAPINE N DIOXIDE; QUETIAPINE N OXIDE; TETRAPROPYLAMMONIUM; TETRAPROPYLAMMONIUM PERRUTHENATE; UNCLASSIFIED DRUG; ZOTEPINE N DIOXIDE; ZOTEPINE N OXIDE;

ARTICLE; CATALYSIS; CHEMICAL MODIFICATION; CHEMICAL REACTION; CHEMICAL REACTION KINETICS; DRUG OXIDATION; DRUG STRUCTURE; DRUG SYNTHESIS;

EID: 84885469213     PISSN: 00397881     EISSN: 1437210X     Source Type: Journal    
DOI: 10.1055/s-0033-1338519     Document Type: Article

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