메뉴 건너뛰기




Volumn 46, Issue 7, 2013, Pages 439-445

CD8+ T-cell auto-reactivity is dependent on the expression of the immunoproteasome subunit LMP7 in exposed to lipopolysaccharide antigen presenting cells and epithelial target cells

Author keywords

Cytotoxic T cell; Immunoproteasome; Lipopolysaccharide; LMP7; Self tolerance

Indexed keywords

LIPOPOLYSACCHARIDE; LOW MOLECULAR MASS POLYPEPTIDE 7; POLYPEPTIDE; SHORT HAIRPIN RNA; UNCLASSIFIED DRUG;

EID: 84885462934     PISSN: 08916934     EISSN: 1607842X     Source Type: Journal    
DOI: 10.3109/08916934.2013.801460     Document Type: Article
Times cited : (8)

References (42)
  • 1
    • 82255164138 scopus 로고    scopus 로고
    • Towards a systems understanding of MHC class i and MHC class II antigen presentation
    • Neefjes, J., M. L. Jongsma, P. Paul, and O. Bakke. 2011. Towards a systems understanding of MHC class I and MHC class II antigen presentation. Nat Rev Immunol. 11: 823-836.
    • (2011) Nat Rev Immunol. , vol.11 , pp. 823-836
    • Neefjes, J.1    Jongsma, M.L.2    Paul, P.3    Bakke, O.4
  • 3
    • 0037066502 scopus 로고    scopus 로고
    • Decoding the patterns of self and nonself by the innate immune system
    • DOI 10.1126/science.1068883
    • Medzhitov, R., and C. A. Janeway Jr. 2002. Decoding the patterns of self and nonself by the innate immune system. Science. 296: 298-300. (Pubitemid 34303673)
    • (2002) Science , vol.296 , Issue.5566 , pp. 298-300
    • Medzhitov, R.1    Janeway Jr., C.A.2
  • 4
    • 0037066427 scopus 로고    scopus 로고
    • The danger model: A renewed sense of self
    • DOI 10.1126/science.1071059
    • Matzinger, P. 2002. The danger model: a renewed sense of self. Science. 296: 301-305. (Pubitemid 34303674)
    • (2002) Science , vol.296 , Issue.5566 , pp. 301-305
    • Matzinger, P.1
  • 5
    • 72949103056 scopus 로고    scopus 로고
    • Proteasomes in immune cells: More than peptide producers?
    • Groettrup, M., C. J. Kirk, and M. Basler. 2010. Proteasomes in immune cells: more than peptide producers? Nat Rev Immunol. 10: 73-78.
    • (2010) Nat Rev Immunol. , vol.10 , pp. 73-78
    • Groettrup, M.1    Kirk, C.J.2    Basler, M.3
  • 6
    • 0032730872 scopus 로고    scopus 로고
    • Dendritic cells up-regulate immunoproteasomes and the proteasome regulator PA28 during maturation
    • Macagno, A., M. Gilliet, F. Sallusto, A. Lanzavecchia, F. O. Nestle, and M. Groettrup. 1999. Dendritic cells up-regulate immunoproteasomes and the proteasome regulator PA28 during maturation. Eur J Immunol. 29: 4037-4042.
    • (1999) Eur J Immunol. , vol.29 , pp. 4037-4042
    • MacAgno, A.1    Gilliet, M.2    Sallusto, F.3    Lanzavecchia, A.4    Nestle, F.O.5    Groettrup, M.6
  • 7
    • 0035214302 scopus 로고    scopus 로고
    • Bipartite regulation of different components of the MHC class I antigen-processing machinery during dendritic cell maturation
    • Li, J., B. Schuler-Thurner, G. Schuler, C. Huber, and B. Seliger. 2001. Bipartite regulation of different components of the MHC class I antigen-processing machinery during dendritic cell maturation. Int Immunol. 13: 1515-1523. (Pubitemid 33133878)
    • (2001) International Immunology , vol.13 , Issue.12 , pp. 1515-1523
    • Li, J.1    Schuler-Thurner, B.2    Schuler, G.3    Huber, C.4    Seliger, B.5
  • 8
    • 0027214605 scopus 로고
    • γ-Interferon and expression of MHC genes regulate peptide hydrolysis by proteasomes
    • DOI 10.1038/365264a0
    • Gaczynska, M., K. L. Rock, and A. L. Goldberg. 1993. Gammainterferon and expression of MHC genes regulate peptide hydrolysis by proteasomes. Nature. 365: 264-267. (Pubitemid 23282087)
    • (1993) Nature , vol.365 , Issue.6443 , pp. 264-267
    • Gaczynska, M.1    Rock, K.L.2    Goldberg, A.L.3
  • 9
    • 0027223877 scopus 로고
    • MHC-linked LMP gene products specifically alter peptidase activities of the proteasome
    • DOI 10.1038/365262a0
    • Driscoll, J., M. G. Brown, D. Finley, and J. J. Monaco. 1993. MHClinked LMP gene products specifically alter peptidase activities of the proteasome. Nature. 365: 262-264. (Pubitemid 23282086)
    • (1993) Nature , vol.365 , Issue.6443 , pp. 262-264
    • Driscoll, J.1    Brown, M.G.2    Finley, D.3    Monaco, J.J.4
  • 10
    • 0029162601 scopus 로고
    • Incorporation of major histocompatibility complex-encoded subunits LMP2 and LMP7 changes the quality of the 20S proteasome polypeptide processing products independent of interferon-gamma
    • Kuckelkorn, U., S. Frentzel, R. Kraft, S. Kostka, M. Groettrup, and P. M. Kloetzel. 1995. Incorporation of major histocompatibility complex-encoded subunits LMP2 and LMP7 changes the quality of the 20S proteasome polypeptide processing products independent of interferon-gamma. Eur J Immunol. 25: 2605-2611.
    • (1995) Eur J Immunol. , vol.25 , pp. 2605-2611
    • Kuckelkorn, U.1    Frentzel, S.2    Kraft, R.3    Kostka, S.4    Groettrup, M.5    Kloetzel, P.M.6
  • 11
    • 72949103056 scopus 로고    scopus 로고
    • Proteasomes in immune cells: More than peptide producers?
    • Groettrup, M., C. J. Kirk, and M. Basler. 2010. Proteasomes in immune cells: more than peptide producers? Nat Rev Immunol. 10: 73-78.
    • (2010) Nat Rev Immunol. , vol.10 , pp. 73-78
    • Groettrup, M.1    Kirk, C.J.2    Basler, M.3
  • 12
    • 72949104779 scopus 로고    scopus 로고
    • Antigen presentation in the thymus for positive selection and central tolerance induction
    • Klein, L., M. Hinterberger, G. Wirnsberger, and B. Kyewski. 2009. Antigen presentation in the thymus for positive selection and central tolerance induction. Nat Rev Immunol. 9: 833-844.
    • (2009) Nat Rev Immunol. , vol.9 , pp. 833-844
    • Klein, L.1    Hinterberger, M.2    Wirnsberger, G.3    Kyewski, B.4
  • 13
    • 0035806246 scopus 로고    scopus 로고
    • + T cells at the levels of T cell repertoire and presentation of viral antigens
    • DOI 10.1084/jem.193.11.1319
    • Chen, W., C. C. Norbury, Y. Cho, J. W. Yewdell, and J. R. Bennink. 2001. Immunoproteasomes shape immunodominance hierarchies of antiviral CD8(\+) T cells at the levels of T cell repertoire and presentation of viral antigens. J Exp Med. 193: 1319-1326. (Pubitemid 32524782)
    • (2001) Journal of Experimental Medicine , vol.193 , Issue.11 , pp. 1319-1326
    • Chen, W.1    Norbury, C.C.2    Cho, Y.3    Yewdell, J.W.4    Bennink, J.R.5
  • 14
    • 7244239199 scopus 로고    scopus 로고
    • Expression of housekeeping and immunoproteasome subunit genes is differentially regulated in positively and negatively selecting thymic stroma subsets
    • DOI 10.1002/eji.200425032
    • Nil, A., E. Firat, V. Sobek, K. Eichmann, and G. Niedermann. 2004. Expression of housekeeping and immunoproteasome subunit genes is differentially regulated in positively and negatively selecting thymic stroma subsets. Eur J Immunol. 34: 2681-2689. (Pubitemid 39430145)
    • (2004) European Journal of Immunology , vol.34 , Issue.10 , pp. 2681-2689
    • Nil, A.1    Firat, E.2    Sobek, V.3    Eichmann, K.4    Niedermann, G.5
  • 17
    • 0034507693 scopus 로고    scopus 로고
    • Impact of negative selection on the T cell repertoire reactive to a self-peptide: A large fraction of T cell clones escapes clonal deletion
    • DOI 10.1016/S1074-7613(00)00080-7
    • Bouneaud, C., P. Kourilsky, and P. Bousso. 2000. Impact of negative selection on the T cell repertoire reactive to a self-peptide: a large fraction of T cell clones escapes clonal deletion. Immunity. 13: 829-840. (Pubitemid 32041805)
    • (2000) Immunity , vol.13 , Issue.6 , pp. 829-840
    • Bouneaud, C.1    Kourilsky, P.2    Bousso, P.3
  • 18
    • 33748621205 scopus 로고    scopus 로고
    • Major histocompatibility complex class I restricted T-cell autoreactivity in human peripheral blood mononuclear cells
    • DOI 10.1016/j.cellimm.2006.06.006, PII S0008874906001006
    • Eleftheriadis, T., S. Voyatzi, G. Antoniadi, C. Kartsios, V. Liakopoulos, P. Paraskevopoulos, and G. Galaktidou. 2006. Major histocompatibility complex class I restricted T-cell autoreactivity in human peripheral blood mononuclear cells. Cell Immunol. 240: 62-67. (Pubitemid 44376374)
    • (2006) Cellular Immunology , vol.240 , Issue.1 , pp. 62-67
    • Eleftheriadis, T.1    Voyatzi, S.2    Antoniadi, G.3    Kartsios, C.4    Liakopoulos, V.5    Paraskevopoulos, P.6    Galaktidou, G.7
  • 19
    • 33746581248 scopus 로고    scopus 로고
    • Regulation of proteolysis by cytokines in the human intestinal epithelial cell line HCT-8: Role of IFNγ
    • DOI 10.1016/j.biochi.2006.01.003, PII S0300908406000046
    • Leblond, J., A. Hubert-Buron, C. Bole-Feysot, P. Ducrotte, P. Dechelotte, and M. Coeffier. 2006. Regulation of proteolysis by cytokines in the human intestinal epithelial cell line HCT-8: role of IFNgamma. Biochimie. 88: 759-765. (Pubitemid 44142160)
    • (2006) Biochimie , vol.88 , Issue.7 , pp. 759-765
    • Leblond, J.1    Hubert-Buron, A.2    Bole-Feysot, C.3    Ducrotte, P.4    Dechelotte, P.5    Coeffier, M.6
  • 20
    • 0035883047 scopus 로고    scopus 로고
    • Tumor necrosis factor-alpha induces coordinated changes in major histocompatibility class i presentation pathway, resulting in increased stability of class i complexes at the cell surface
    • Hallermalm, K., K. Seki, C. Wei, C. Castelli, L. Rivoltini, R. Kiessling, and J. Levitskaya. 2001. Tumor necrosis factor-alpha induces coordinated changes in major histocompatibility class I presentation pathway, resulting in increased stability of class I complexes at the cell surface. Blood. 98: 1108-1115.
    • (2001) Blood. , vol.98 , pp. 1108-1115
    • Hallermalm, K.1    Seki, K.2    Wei, C.3    Castelli, C.4    Rivoltini, L.5    Kiessling, R.6    Levitskaya, J.7
  • 22
    • 0035892754 scopus 로고    scopus 로고
    • Immunoproteasomes largely replace constitutive proteasomes during an antiviral and antibacterial immune response in the liver
    • Khan, S., M. van den Broek, K. Schwarz, R. de Giuli, P. A. Diener, and M. Groettrup. 2001. Immunoproteasomes largely replace constitutive proteasomes during an antiviral and antibacterial immune response in the liver. J Immunol. 167: 6859-6868. (Pubitemid 33144178)
    • (2001) Journal of Immunology , vol.167 , Issue.12 , pp. 6859-6868
    • Khan, S.1    Van Den Broek, M.2    Schwarz, K.3    De Giuli, R.4    Diener, P.-A.5    Groettrup, M.6
  • 23
    • 0037105392 scopus 로고    scopus 로고
    • Regulation of immunoproteasome subunit expression in vivo following pathogenic fungal infection
    • Barton, L. F., M. Cruz, R. Rangwala, G. S. Deepe Jr., and J. J. Monaco. 2002. Regulation of immunoproteasome subunit expression in vivo following pathogenic fungal infection. J Immunol. 169: 3046-3052. (Pubitemid 35013148)
    • (2002) Journal of Immunology , vol.169 , Issue.6 , pp. 3046-3052
    • Barton, L.F.1    Cruz, M.2    Rangwala, R.3    Deepe Jr., G.S.4    Monaco, J.J.5
  • 24
    • 0242468319 scopus 로고    scopus 로고
    • Bioinformatic analysis of functional differences between the immunoproteasome and the constitutive proteasome
    • DOI 10.1007/s00251-003-0585-6
    • Kesmir, C., V. van Noort, R. J. de Boer, and P. Hogeweg. 2003. Bioinformatic analysis of functional differences between the immunoproteasome and the constitutive proteasome. Immunogenetics. 55: 437-449. (Pubitemid 37378484)
    • (2003) Immunogenetics , vol.55 , Issue.7 , pp. 437-449
    • Kesmir, C.1    Van Noort, V.2    De Boer, R.J.3    Hogeweg, P.4
  • 26
    • 33846083832 scopus 로고    scopus 로고
    • Role of immunoproteasome catalytic subunits in the immune response to hepatitis B virus
    • DOI 10.1128/JVI.01779-06
    • Robek, M. D., M. L. Garcia, B. S. Boyd, and F. V. Chisari. 2007. Role of immunoproteasome catalytic subunits in the immune response to hepatitis B virus. J Virol. 81: 483-491. (Pubitemid 46067875)
    • (2007) Journal of Virology , vol.81 , Issue.2 , pp. 483-491
    • Robek, M.D.1    Garcia, M.L.2    Boyd, B.S.3    Chisari, F.V.4
  • 27
    • 39649085607 scopus 로고    scopus 로고
    • Immunoproteasome down-modulation enhances the ability of dendritic cells to stimulate antitumor immunity
    • DOI 10.1182/blood-2007-04-083188
    • Dannull, J., D. T. Lesher, R. Holzknecht, W. Qi, G. Hanna, H. Seigler, D. S. Tyler, and S. K. Pruitt. 2007. Immunoproteasome down-modulation enhances the ability of dendritic cells to stimulate antitumor immunity. Blood. 110: 4341-4350. (Pubitemid 351377799)
    • (2007) Blood , vol.110 , Issue.13 , pp. 4341-4350
    • Dannull, J.1    Lesher, D.-T.2    Holzknecht, R.3    Qi, W.4    Hanna, G.5    Seigler, H.6    Tyler, D.S.7    Pruitt, S.K.8
  • 28
    • 78650359178 scopus 로고    scopus 로고
    • Differences in the production of spliced antigenic peptides by the standard proteasome and the immunoproteasome
    • Dalet, A., V. Stroobant, N. Vigneron, and B. J. Van den Eynde. 2011. Differences in the production of spliced antigenic peptides by the standard proteasome and the immunoproteasome. Eur J Immunol. 41: 39-46.
    • (2011) Eur J Immunol. , vol.41 , pp. 39-46
    • Dalet, A.1    Stroobant, V.2    Vigneron, N.3    Eynde Den Van, B.J.4
  • 30
    • 83155175088 scopus 로고    scopus 로고
    • The existence of two types of proteasome, the constitutive proteasome and the immunoproteasome, may serve as another layer of protection against autoimmunity
    • Eleftheriadis, T. 2012. The existence of two types of proteasome, the constitutive proteasome and the immunoproteasome, may serve as another layer of protection against autoimmunity. Med Hypotheses. 78: 138-141.
    • (2012) Med Hypotheses. , vol.78 , pp. 138-141
    • Eleftheriadis, T.1
  • 35
    • 67650388103 scopus 로고    scopus 로고
    • A selective inhibitor of the immunoproteasome subunit LMP7 blocks cytokine production and attenuates progression of experimental arthritis
    • Muchamuel, T., M. Basler, M. A. Aujay, E. Suzuki, K. W. Kalim, C. Lauer, C. Sylvain, et al. 2009. A selective inhibitor of the immunoproteasome subunit LMP7 blocks cytokine production and attenuates progression of experimental arthritis. Nat Med. 15: 781-787.
    • (2009) Nat Med. , vol.15 , pp. 781-787
    • Muchamuel, T.1    Basler, M.2    Aujay, M.A.3    Suzuki, E.4    Kalim, K.W.5    Lauer, C.6    Sylvain, C.7
  • 36
    • 77956198116 scopus 로고    scopus 로고
    • Prevention of experimental colitis by a selective inhibitor of the immunoproteasome
    • Basler, M., M. Dajee, C. Moll, M. Groettrup, and C. J. Kirk. 2010. Prevention of experimental colitis by a selective inhibitor of the immunoproteasome. J Immunol. 185: 634-641.
    • (2010) J Immunol. , vol.185 , pp. 634-641
    • Basler, M.1    Dajee, M.2    Moll, C.3    Groettrup, M.4    Kirk, C.J.5
  • 37
    • 84859959246 scopus 로고    scopus 로고
    • Prophylactic and therapeutic efficacies of a selective inhibitor of the immunoproteasome for Hashimoto's thyroiditis, but not for Graves' hyperthyroidism, in mice
    • Nagayama, Y., M. Nakahara, M. Shimamura, I. Horie, K. Arima, and N. Abiru. 2012. Prophylactic and therapeutic efficacies of a selective inhibitor of the immunoproteasome for Hashimoto's thyroiditis, but not for Graves' hyperthyroidism, in mice. Clin Exp Immunol. 168: 268-273.
    • (2012) Clin Exp Immunol. , vol.168 , pp. 268-273
    • Nagayama, Y.1    Nakahara, M.2    Shimamura, M.3    Horie, I.4    Arima, K.5    Abiru, N.6
  • 38
    • 0016345568 scopus 로고
    • Restriction of in vitro T cell-mediated cytotoxicity in lymphocytic choriomeningitis within a syngeneic or semiallogeneic system
    • Zinkernagel, R. M., and P. C. Doherty. 1974. Restriction of in vitro T cell-mediated cytotoxicity in lymphocytic choriomeningitis within a syngeneic or semiallogeneic system. Nature. 248: 701-702.
    • (1974) Nature. , vol.248 , pp. 701-702
    • Zinkernagel, R.M.1    Doherty, P.C.2
  • 39
    • 84856547851 scopus 로고    scopus 로고
    • Mechanisms controlling granule-mediated cytolytic activity of cytotoxic T lymphocytes
    • Anikeeva, N., and Y. Sykulev. 2011. Mechanisms controlling granule-mediated cytolytic activity of cytotoxic T lymphocytes. Immunol Res. 51: 183-194.
    • (2011) Immunol Res. , vol.51 , pp. 183-194
    • Anikeeva, N.1    Sykulev, Y.2
  • 40
    • 78751552261 scopus 로고    scopus 로고
    • Regulatory immune cell subsets in autoimmunity
    • La Cava, A. 2011. Regulatory immune cell subsets in autoimmunity. Autoimmunity. 44: 1-2.
    • (2011) Autoimmunity. , vol.44 , pp. 1-2
    • La Cava, A.1
  • 41
    • 84859835474 scopus 로고    scopus 로고
    • Protective role of anti-idiotypic antibodies in autoimmunity-lessons for type 1 diabetes
    • Hampe, C. S. 2012. Protective role of anti-idiotypic antibodies in autoimmunity-lessons for type 1 diabetes. Autoimmunity. 45: 320-331.
    • (2012) Autoimmunity. , vol.45 , pp. 320-331
    • Hampe, C.S.1
  • 42
    • 84867963556 scopus 로고    scopus 로고
    • When autologous chromatin becomes a foe
    • Munoz, L. E., and M. Herrmann. 2012. When autologous chromatin becomes a foe. Autoimmunity. 45: 565-567.
    • (2012) Autoimmunity. , vol.45 , pp. 565-567
    • Munoz, L.E.1    Herrmann, M.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.