Kinetics of action of a two-stage pro-inhibitor of serine β-lactamases

Biochemistry

Volumn 52, Issue 40, 2013, Pages 7060-7070

  Tilvawala, Ronak ^a   Pratt, R F ^a  

^a WESLEYAN UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ENZYME ACTIVE SITES; ENZYME SPECIFICITY; FACILE REACTION; HYDROXAMIC ACIDS; LACTAMASES; PHTHALIC ANHYDRIDES; SPONTANEOUS HYDROLYSIS;

AMINO ACIDS; CARBOXYLATION; CHEMICAL COMPOUNDS;

ENZYMES;

3 BENZOYL 3H BENZO[D][1,2]OXAZINE 1,4 DIONE; 3 METHYL 3H BENZO[D][1,2]OXAZINE 1,4 DIONE; 3H BENZO[D][1,2]OXAZINE 1,4 DIONE; BETA LACTAMASE INHIBITOR; HYDROXAMIC ACID; N (BENZYLOXYCARBONYL) N (BENZOYL)HYDROXYLAMINE; N (TERT BUTOXYCARBONYL) O (2 CARBOXYBENZOYL) HYDROXYLAMINE; UNCLASSIFIED DRUG;

ARTICLE; CHEMICAL STRUCTURE; ENZYME ACTIVE SITE; ENZYME INHIBITION; HYDROLYSIS; PRIORITY JOURNAL; PROTON NUCLEAR MAGNETIC RESONANCE; SYNTHESIS;

ACYLATION; BETA-LACTAMASES; CATALYTIC DOMAIN; ENZYME INHIBITORS; HYDROLYSIS; HYDROXAMIC ACIDS; KINETICS; PHTHALIC ANHYDRIDES; PRODRUGS;

EID: 84885452400     PISSN: 00062960     EISSN: 15204995     Source Type: Journal    
DOI: 10.1021/bi400873r     Document Type: Article

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