Tea polyphenols as novel and potent inhibitory substances against renin activity

Journal of Agricultural and Food Chemistry

Volumn 61, Issue 40, 2013, Pages 9697-9704

  Li, Fengjuan ^a,b   Ohnishi Kameyama, Mayumi ^a   Takahashi, Yoko ^a   Yamaki, Kohji ^a  

^a NATIONAL FOOD RESEARCH INSTITUTE   (Japan)

^b TIANJIN UNIVERSITY OF SCIENCE AND TECHNOLOGY   (China)

Author keywords

black tea; identification; polyphenol; renin inhibition; theasinensin

Indexed keywords

ACTIVE COMPOUNDS; BLACK TEA; GRADIENT HIGH PERFORMANCE LIQUID CHROMATOGRAPHIES; INHIBITORY ACTIVITY; POLYPHENOLS; POTENT INHIBITOR; TEA POLYPHENOLS; THEASINENSIN;

IDENTIFICATION (CONTROL SYSTEMS); SPECTROSCOPIC ANALYSIS;

BEVERAGES;

CATECHIN; DRUG DERIVATIVE; EPIGALLOCATECHIN 3 O GALLATE EPIGALLOCATECHIN DIMER; EPIGALLOCATECHIN-3-O-GALLATE EPIGALLOCATECHIN DIMER; PHENOL DERIVATIVE; PLANT EXTRACT; POLYPHENOL; RENIN; STRICTININ;

ARTICLE; CHEMISTRY; DRUG ANTAGONISM; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; IC 50; MASS SPECTROMETRY; METABOLISM; TEA;

CATECHIN; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; INHIBITORY CONCENTRATION 50; MASS SPECTROMETRY; PHENOLS; PLANT EXTRACTS; POLYPHENOLS; RENIN; TEA;

EID: 84885446304     PISSN: 00218561     EISSN: 15205118     Source Type: Journal    
DOI: 10.1021/jf403710b     Document Type: Article

References (35)

1. Chen, Z. Y.; Peng, C.; Jiao, R.; Wong, Y. M.; Yang, N.; Huang, Y. Anti-hypertensive Nutraceuticals and Functional Foods J. Agric. Food Chem. 2009, 57, 4485-4499
2. Ondetti, M. A.; Cushman, D. W. Inhibition of the Renin-Angiotensin System. A New Approach to the Therapy of Hypertension J. Med. Chem. 1981, 24, 355-361 (Pubitemid 11151637)
3. Deng, Y. F.; Aluko, R. E.; Jin, Q.; Zhang, Y.; Yuan, L. J. Inhibitory Activities of Baicalin against Renin and Angiotensin-Converting Enzyme Pharm. Biol. 2012, 50, 401-406
4. Lynch, K. R.; Peach, M. J. Molecular Biology of Angiotensinogen Hypertension 1991, 17, 263-269
5. Ajibola, C. F.; Eleyinmi, A. F.; Aluko, R. E. Kinetics of the Inhibition of Renin and Angiotensin I Converting Enzyme by Polar and Non-Polar Polyphenolic Extracts of Vernonia amygdalina and Gongronema latifolium Leaves Plant Foods Hum. Nutr. 2011, 66, 320-327
6. Hernández-Ledesma, B.; Contreras, M. M.; Recio, I. Antihypertensive Peptides: Production, Bioavailability and Incorporation into Foods Adv. Colloid Interface Sci. 2011, 165, 23-35
7. Takahashi, S.; Hori, K.; Ogasawara, H.; Hiwatashi, K.; Sugiyama, T. Effects of Nucleotides on the Interaction of Renin with GlcNAc 2-Epimerase (Renin Binding Protein, RnBP) J. Biochem. 2006, 140, 725-730 (Pubitemid 46065498)
8. Matsoukas, M. T.; Zoumpoulakis, P.; Tselios, T. Conformational Analysis of Aliskiren, A Potent Renin Inhibitor, Using High-Resolution Nuclear Magnetic Resonance and Molecular Dynamics Simulations J. Chem. Inf. Model. 2011, 51, 2386-2397
9. Ishchenko, A.; Liu, Z.; Lindblom, P.; Wu, G.; Jim, K. C.; Gregg, R. D.; Claremon, D. A.; Singh, S. B. Sturcture-Based Design Technology Contour and Its Application to the Design of Renin Inhibitors J. Chem. Inf. Model. 2012, 52, 2089-2097
10. Takahashi, S.; Hori, K.; Shinbo, M.; Hiwatashi, K.; Gotoh, T.; Yamada, S. Isolation of Human Renin Inhibitor from Soybean: Soyasaponin I Is the Novel Human Renin Inhibitor in Soybean Biosci. Biotechnol. Biochem. 2008, 72, 3232-3236
11. Takahashi, S.; Tokiwano, T.; Hata, K.; Kodama, I.; Hokari, M.; Suzuki, N.; Yoshizawa, Y.; Gotoh, T. the Occurrence of Renin Inhibitor in Rice: Isolation, Identification and Structure-Function Relationship Biosci. Biotechnol. Biochem. 2010b, 74, 1713-1715
12. Li, H.; Aluko, R. E. Identification and Inhibitory Properties of Multifunctional Peptides from Pea Protein Hydrolysate J. Agric. Food Chem. 2010, 58, 11471-11476
13. Hiwatashi, K.; Shirakawa, H.; Hori, K.; Yoshiki, Y.; Suzuki, N.; Hokari, M.; Komai, M.; Takahashi, S. Reduction of Blood Pressure by Soybean Saponins, Renin Inhibitors from Soybean, In Spontaneously Hypertensive Rats Biosci. Biotechnol. Biochem. 2010, 74, 2310-2312
14. Takahashi, S.; Hori, K.; Hokari, M.; Gotoh, T.; Sugiyama, T. Inhibition of Human Renin Activity by Saponins Biomed. Res. 2010a, 31, 155-159
15. Li, F.; Takahashi, Y.; Yamaki, K. Inhibitory Effect of Catechin-Related Compounds on Renin Activity Biomed. Res. 2013, 34, 167-171
16. Negishi, H.; Xu, J. W.; Ikeda, K.; Njelekela, M.; Nara, Y.; Yamori, Y. Black and Green Tea Polyphenols Attenuate Blood Pressure Increases in Stroke-Prone Spontaneously Hypertensive Rats J. Nutr. 2004, 134, 38-42 (Pubitemid 38057420)
17. López-Sepúlveda, R.; Jiménez, R.; Romero, M.; Zarzuelo, M. J.; Sánchez, M.; Gómez-Guzmán, M.; Vargas, F.; O'Valle, F.; Zarzuelo, A.; Pérez-Vizcaíno, F.; Duarte, J. Wine Polyphenols Improve Endothelial Function in Large Vessels of Female Spontaneously Hypertensive Rats Hypertension 2008, 51, 1088-1095 (Pubitemid 351398987)
18. Cienfuegos-Jovellanos, E.; Quinones, M. d. M.; Muguerza, B.; Moulay, L.; Miguel, M.; Aleixandre, A. Antihypertensive Effect of a Polyphenol-Rich Cocoa Powder Industrially Processed to Preserve the Original Flavonoids of the Cocoa Beans J. Agric. Food Chem. 2009, 57, 6156-6162
19. Quinones, M.; Miguel, M.; Muguerza, B.; Aleixandre, A. Effect of a Cocoa Polyphenol Extract in Spontaneously Hypertensive Rats Food Funct. 2011, 2, 649-653
20. Mukai, Y.; Sato, S. Polyphenol-Containing Azuki Bean (Vigna angularis) Seed Coats Attenuate Vascular Oxidative Stress and Inflammation in Spontaneously Hypertensive Rats J. Nutr. Biochem. 2011, 22, 16-21
21. Actis-Goretta, L.; Ottaviani, J. I.; Fraga, C. G. Inhibition of Angiotensin Converting Enzyme Activity by Flavanol-Rich Foods J. Agric. Food Chem. 2006, 54, 229-234 (Pubitemid 43119944)
22. Schnorr, O.; Brossette, T.; Momma, T. Y.; Kleinbongard, P.; Keen, C. L.; Schroeter, H.; Sies, H. Cocoa Flavanols Lower Vascular Arginase Activity in Human Endothelial Cells in Vitro And In Erythrocytes in Vivo Arch. Biochem. Biophys. 2008, 476, 211-215
23. Takahashi, S.; Hori, K.; Kumagai, M.; Wakabayashi, S. Human Renin Inhibitory Activity in Legumes J. Biol. Macromol. 2007, 7, 49-54
24. Udenigwe, C. C.; Lin, Y. S.; Hou, W. C.; Aluko, R. E. Kinetics of the Inhibition of Renin and Angiotensin I-Converting Enzyme by Flaxseed Protein Hydrolysate Fractions J. Funct. Foods 2009, 1, 199-207
25. Tanida, M.; Tsuruoka, N.; Shen, J.; Kiso, Y.; Nagai, K. Effects of Oolong Tea on Renal Sympathetic Nerve Activity and Spontaneous Hypertension in Rats Metabolism 2008, 57, 526-534 (Pubitemid 351317968)
26. Khan, N.; Mukhtar, H. Tea Polyphenols for Health Promotion Life Sci. 2007, 81, 519-533 (Pubitemid 47212236)
27. Yung, L. M.; Leung, F. P.; Wong, W. T.; Tian, X. Y.; Yung, L. H.; Chen, Z. Y.; Yao, X. Q.; Huang, Y. Tea Polyphenols Benefit Vascular Function Inflammopharmacology 2008, 16, 230-234
28. Dou, J.; Lee, V. S. Y.; Tzen, J. T. C.; Lee, M. R. Identification and Comparison of Phenolic Compounds in the Preparation of Oolong Tea Manufactured by Semifermentation and Drying Processes J. Agric. Food Chem. 2007, 55, 7462-7468 (Pubitemid 47492302)
29. Lin, L. Z.; Chen, P.; Harnly, J. M. New Phenolic Components and Chromatographic Profiles of Green and Fermented Teas J. Agric. Food Chem. 2008, 56, 8130-8140
30. n Analysis of Phenolic Compounds and Purine Alkaloids in Green and Black Tea J. Agric. Food Chem. 2004, 52, 2807-2815
31. Gondoin, A.; Grussu, D.; Stewart, D.; McDougall, G. J. White and Green Tea Polyphenols Inhibit Pancreatic Lipase in Vitro Food Res. Int. 2010, 43, 1537-1544
32. Okello, E. J.; Leylabi, R.; McDougall, G. J. Inhibition of Acetylcholinesterase by Green and White Tea and Their Simulated Intestinal Metabolites Food Funct. 2012, 3, 651-661
33. Yuan, L.; Wu, J.; Aluko, R. E.; Ye, X. Kinetics of Renin Inhibition by Sodium Houttuyfonate Analogs Biosci. Biotechnol. Biochem. 2006, 70, 2275-2280 (Pubitemid 44451907)
34. Isaacs, C. E.; Xu, W.; Merz, G.; Hillier, S.; Rohan, L.; Wen, G. Y. Digallate Dimers of (-)-Epigallocatechin Gallate Inactivate Herpes Simplex Virus Antimicrob. Agents Chemother.. 2011, 55, 5646-5653
35. Pan, M. H.; Liang, Y. C.; Lin-Shiau, S. Y.; Zhu, N. Q.; Ho, C. T.; Lin, J. K. Induction of Apoptosis by the Oolong Tea Polyphenol Theasinensin a through Cytochrome c Release and Activation of Caspase-9 and Caspase-3 in Human U937 Cells J. Agric. Food Chem. 2000, 48, 6337-6346