메뉴 건너뛰기




Volumn 8, Issue 10, 2013, Pages

Identification of microRNAs That Regulate TLR2-Mediated Trophoblast Apoptosis and Inhibition of IL-6 mRNA

Author keywords

[No Author keywords available]

Indexed keywords

INTERLEUKIN 6; MESSENGER RNA; MICRORNA; MICRORNA 149; MICRORNA 155 5P; MICRORNA 23A; MICRORNA 23B; MICRORNA 329; MICRORNA 347; MICRORNA LET 7C; PEPTIDOGLYCAN; TOLL LIKE RECEPTOR 2; TOLL LIKE RECEPTOR 6; TRANSCRIPTION FACTOR RELA; UNCLASSIFIED DRUG;

EID: 84885445127     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0077249     Document Type: Article
Times cited : (34)

References (57)
  • 1
    • 33846413943 scopus 로고    scopus 로고
    • The role of inflammation and infection in preterm birth
    • doi:10.1055/s-2006-956773
    • Romero R, Espinoza J, Gonçalves LF, Kusanovic JP, Friel L, et al. (2007) The role of inflammation and infection in preterm birth. Semin Reprod Med 25: 21-39. doi:10.1055/s-2006-956773. PubMed: 17205421.
    • (2007) Semin Reprod Med , vol.25 , pp. 21-39
    • Romero, R.1    Espinoza, J.2    Gonçalves, L.F.3    Kusanovic, J.P.4    Friel, L.5
  • 2
    • 0034682251 scopus 로고    scopus 로고
    • Intrauterine infection and preterm delivery
    • doi:10.1056/NEJM200005183422007
    • Goldenberg RL, Hauth JC, Andrews WW, (2000) Intrauterine infection and preterm delivery. N Engl J Med 342: 1500-1507. doi:10.1056/NEJM200005183422007. PubMed: 10816189.
    • (2000) N Engl J Med , vol.342 , pp. 1500-1507
    • Goldenberg, R.L.1    Hauth, J.C.2    Andrews, W.W.3
  • 3
    • 79960451801 scopus 로고    scopus 로고
    • The origins and end-organ consequence of pre-eclampsia
    • doi:10.1016/j.bpobgyn.2011.01.005
    • Eastabrook G, Brown M, Sargent I, (2011) The origins and end-organ consequence of pre-eclampsia. Best Pract Res Clin Obstet Gynaecol 25: 435-447. doi:10.1016/j.bpobgyn.2011.01.005. PubMed: 21367667.
    • (2011) Best Pract Res Clin Obstet Gynaecol , vol.25 , pp. 435-447
    • Eastabrook, G.1    Brown, M.2    Sargent, I.3
  • 4
    • 44449091615 scopus 로고    scopus 로고
    • TLR6 modulates first trimester trophoblast responses to peptidoglycan
    • Abrahams VM, Aldo PB, Murphy SP, Visintin I, Koga K, et al. (2008) TLR6 modulates first trimester trophoblast responses to peptidoglycan. J Immunol 180: 6035-6043. PubMed: 18424724.
    • (2008) J Immunol , vol.180 , pp. 6035-6043
    • Abrahams, V.M.1    Aldo, P.B.2    Murphy, S.P.3    Visintin, I.4    Koga, K.5
  • 5
    • 0142244180 scopus 로고    scopus 로고
    • A new model for inflammation-induced preterm birth: the role of platelet-activating factor and Toll-like receptor-4
    • doi:10.1016/S0002-9440(10)63567-5
    • Elovitz MA, Wang Z, Chien EK, Rychlik DF, Phillippe M, (2003) A new model for inflammation-induced preterm birth: the role of platelet-activating factor and Toll-like receptor-4. Am J Pathol 163: 2103-2111. doi:10.1016/S0002-9440(10)63567-5. PubMed: 14578208.
    • (2003) Am J Pathol , vol.163 , pp. 2103-2111
    • Elovitz, M.A.1    Wang, Z.2    Chien, E.K.3    Rychlik, D.F.4    Phillippe, M.5
  • 6
    • 34648823296 scopus 로고    scopus 로고
    • Activation of toll-like receptors 2 or 3 and preterm delivery in the mouse
    • doi:10.1177/1933719107302959
    • Ilievski V, Lu SJ, Hirsch E, (2007) Activation of toll-like receptors 2 or 3 and preterm delivery in the mouse. Reprod Sci 14: 315-320. doi:10.1177/1933719107302959. PubMed: 17644803.
    • (2007) Reprod Sci , vol.14 , pp. 315-320
    • Ilievski, V.1    Lu, S.J.2    Hirsch, E.3
  • 7
    • 60449092852 scopus 로고    scopus 로고
    • Activation of TLR3 in the trophoblast is associated with preterm delivery
    • doi:10.1111/j.1600-0897.2008.00682.x
    • Koga K, Cardenas I, Aldo P, Abrahams VM, Peng B, et al. (2009) Activation of TLR3 in the trophoblast is associated with preterm delivery. Am J Reprod Immunol 61: 196-212. doi:10.1111/j.1600-0897.2008.00682.x. PubMed: 19239422.
    • (2009) Am J Reprod Immunol , vol.61 , pp. 196-212
    • Koga, K.1    Cardenas, I.2    Aldo, P.3    Abrahams, V.M.4    Peng, B.5
  • 8
    • 0037962024 scopus 로고    scopus 로고
    • Regulation of FasL/Fas in human trophoblasts: possible implications for chorioamnionitis
    • doi:10.1095/biolreprod.102.013102
    • Balkundi DR, Ziegler JA, Watchko JF, Craven C, Trucco M, (2003) Regulation of FasL/Fas in human trophoblasts: possible implications for chorioamnionitis. Biol Reprod 69: 718-724. doi:10.1095/biolreprod.102.013102. PubMed: 12700199.
    • (2003) Biol Reprod , vol.69 , pp. 718-724
    • Balkundi, D.R.1    Ziegler, J.A.2    Watchko, J.F.3    Craven, C.4    Trucco, M.5
  • 9
    • 28844503868 scopus 로고    scopus 로고
    • The role of apoptosis in the regulation of trophoblast survival and differentiation during pregnancy
    • doi:10.1210/er.2005-0003
    • Straszewski-Chavez SL, Abrahams VM, Mor G, (2005) The role of apoptosis in the regulation of trophoblast survival and differentiation during pregnancy. Endocr Rev 26: 877-897. doi:10.1210/er.2005-0003. PubMed: 15901666.
    • (2005) Endocr Rev , vol.26 , pp. 877-897
    • Straszewski-Chavez, S.L.1    Abrahams, V.M.2    Mor, G.3
  • 10
    • 33745847809 scopus 로고    scopus 로고
    • Chlamydia heat shock protein 60 induces trophoblast apoptosis through TLR4
    • Equils O, Lu D, Gatter M, Witkin SS, Bertolotto C, et al. (2006) Chlamydia heat shock protein 60 induces trophoblast apoptosis through TLR4. J Immunol 177: 1257-1263. PubMed: 16818785.
    • (2006) J Immunol , vol.177 , pp. 1257-1263
    • Equils, O.1    Lu, D.2    Gatter, M.3    Witkin, S.S.4    Bertolotto, C.5
  • 12
    • 77954480383 scopus 로고    scopus 로고
    • Human TLRs 10 and 1 share common mechanisms of innate immune sensing but not signaling
    • doi:10.4049/jimmunol.0901888
    • Guan Y, Ranoa DR, Jiang S, Mutha SK, Li X, et al. (2010) Human TLRs 10 and 1 share common mechanisms of innate immune sensing but not signaling. J Immunol 184: 5094-5103. doi:10.4049/jimmunol.0901888. PubMed: 20348427.
    • (2010) J Immunol , vol.184 , pp. 5094-5103
    • Guan, Y.1    Ranoa, D.R.2    Jiang, S.3    Mutha, S.K.4    Li, X.5
  • 13
    • 20044368019 scopus 로고    scopus 로고
    • Human TLR10 is a functional receptor, expressed by B cells and plasmacytoid dendritic cells, which activates gene transcription through MyD88
    • Hasan U, Chaffois C, Gaillard C, Saulnier V, Merck E, et al. (2005) Human TLR10 is a functional receptor, expressed by B cells and plasmacytoid dendritic cells, which activates gene transcription through MyD88. J Immunol 174: 2942-2950. PubMed: 15728506.
    • (2005) J Immunol , vol.174 , pp. 2942-2950
    • Hasan, U.1    Chaffois, C.2    Gaillard, C.3    Saulnier, V.4    Merck, E.5
  • 14
    • 0034610291 scopus 로고    scopus 로고
    • The repertoire for pattern recognition of pathogens by the innate immune system is defined by cooperation between toll-like receptors
    • doi:10.1073/pnas.250476497
    • Ozinsky A, Underhill DM, Fontenot JD, Hajjar AM, Smith KD, et al. (2000) The repertoire for pattern recognition of pathogens by the innate immune system is defined by cooperation between toll-like receptors. Proc Natl Acad Sci U S A 97: 13766-13771. doi:10.1073/pnas.250476497. PubMed: 11095740.
    • (2000) Proc Natl Acad Sci U S A , vol.97 , pp. 13766-13771
    • Ozinsky, A.1    Underhill, D.M.2    Fontenot, J.D.3    Hajjar, A.M.4    Smith, K.D.5
  • 15
    • 84876304588 scopus 로고    scopus 로고
    • Cutting-Edge Report: TLR10 Plays a Role in Mediating Bacterial Peptidoglycan-Induced Trophoblast Apoptosis
    • doi:10.1111/aji.12065
    • Mulla MJ, Myrtolli K, Tadesse S, Stanwood NL, Gariepy A, et al. (2013) Cutting-Edge Report: TLR10 Plays a Role in Mediating Bacterial Peptidoglycan-Induced Trophoblast Apoptosis. Am J Reprod Immunol 69: 449-453. doi:10.1111/aji.12065. PubMed: 23279063.
    • (2013) Am J Reprod Immunol , vol.69 , pp. 449-453
    • Mulla, M.J.1    Myrtolli, K.2    Tadesse, S.3    Stanwood, N.L.4    Gariepy, A.5
  • 16
    • 0347444723 scopus 로고    scopus 로고
    • MicroRNAs: genomics, biogenesis, mechanism, and function
    • doi:10.1016/S0092-8674(04)00045-5
    • Bartel DP, (2004) MicroRNAs: genomics, biogenesis, mechanism, and function. Cell 116: 281-297. doi:10.1016/S0092-8674(04)00045-5. PubMed: 14744438.
    • (2004) Cell , vol.116 , pp. 281-297
    • Bartel, D.P.1
  • 17
    • 79952186298 scopus 로고    scopus 로고
    • MicroRNAs: the fine-tuners of Toll-like receptor signalling
    • doi:10.1038/nri2957
    • O'Neill LA, Sheedy FJ, McCoy CE, (2011) MicroRNAs: the fine-tuners of Toll-like receptor signalling. Nat Rev Immunol 11: 163-175. doi:10.1038/nri2957. PubMed: 21331081.
    • (2011) Nat Rev Immunol , vol.11 , pp. 163-175
    • O'Neill, L.A.1    Sheedy, F.J.2    McCoy, C.E.3
  • 18
    • 79952509217 scopus 로고    scopus 로고
    • Expression profile of microRNAs and mRNAs in human placentas from pregnancies complicated by preeclampsia and preterm labor
    • doi:10.1177/1933719110374115
    • Mayor-Lynn K, Toloubeydokhti T, Cruz AC, Chegini N, (2011) Expression profile of microRNAs and mRNAs in human placentas from pregnancies complicated by preeclampsia and preterm labor. Reprod Sci 18: 46-56. doi:10.1177/1933719110374115. PubMed: 21079238.
    • (2011) Reprod Sci , vol.18 , pp. 46-56
    • Mayor-Lynn, K.1    Toloubeydokhti, T.2    Cruz, A.C.3    Chegini, N.4
  • 19
    • 78650512404 scopus 로고    scopus 로고
    • miR-200 family and targets, ZEB1 and ZEB2, modulate uterine quiescence and contractility during pregnancy and labor
    • doi:10.1073/pnas.1008301107
    • Renthal NE, Chen CC, Williams KC, Gerard RD, Prange-Kiel J, et al. (2010) miR-200 family and targets, ZEB1 and ZEB2, modulate uterine quiescence and contractility during pregnancy and labor. Proc Natl Acad Sci U S A 107: 20828-20833. doi:10.1073/pnas.1008301107. PubMed: 21079000.
    • (2010) Proc Natl Acad Sci U S A , vol.107 , pp. 20828-20833
    • Renthal, N.E.1    Chen, C.C.2    Williams, K.C.3    Gerard, R.D.4    Prange-Kiel, J.5
  • 20
    • 84866094382 scopus 로고    scopus 로고
    • MicroRNA-155 inhibits proliferation and migration of human extravillous trophoblast derived HTR-8/SVneo cells via down-regulating cyclin D1
    • doi:10.1016/j.placenta.2012.07.012
    • Dai Y, Qiu Z, Diao Z, Shen L, Xue P, et al. (2012) MicroRNA-155 inhibits proliferation and migration of human extravillous trophoblast derived HTR-8/SVneo cells via down-regulating cyclin D1. Placenta 33: 824-829. doi:10.1016/j.placenta.2012.07.012. PubMed: 22858023.
    • (2012) Placenta , vol.33 , pp. 824-829
    • Dai, Y.1    Qiu, Z.2    Diao, Z.3    Shen, L.4    Xue, P.5
  • 21
    • 84870682228 scopus 로고    scopus 로고
    • microRNA-29b contributes to pre-eclampsia through its effects on apoptosis, invasion and angiogenesis of trophoblast cells
    • doi:10.1042/CS20120121
    • Li P, Guo W, Du L, Zhao J, Wang Y, et al. (2013) microRNA-29b contributes to pre-eclampsia through its effects on apoptosis, invasion and angiogenesis of trophoblast cells. Clin Sci (Lond) 124: 27-40. doi:10.1042/CS20120121. PubMed: 22716646.
    • (2013) Clin Sci (Lond) , vol.124 , pp. 27-40
    • Li, P.1    Guo, W.2    Du, L.3    Zhao, J.4    Wang, Y.5
  • 22
    • 84865858694 scopus 로고    scopus 로고
    • MicroRNA-378a-5p promotes trophoblast cell survival, migration and invasion by targeting Nodal
    • doi:10.1242/jcs.096412
    • Luo L, Ye G, Nadeem L, Fu G, Yang BB, et al. (2012) MicroRNA-378a-5p promotes trophoblast cell survival, migration and invasion by targeting Nodal. J Cell Sci 125: 3124-3132. doi:10.1242/jcs.096412. PubMed: 22454525.
    • (2012) J Cell Sci , vol.125 , pp. 3124-3132
    • Luo, L.1    Ye, G.2    Nadeem, L.3    Fu, G.4    Yang, B.B.5
  • 23
    • 84858416153 scopus 로고    scopus 로고
    • MiRNA-mediated control of HLA-G expression and function
    • doi:10.1371/journal.pone.0033395
    • Manaster I, Goldman-Wohl D, Greenfield C, Nachmani D, Tsukerman P, et al. (2012) MiRNA-mediated control of HLA-G expression and function. PLOS ONE 7: e33395. doi:10.1371/journal.pone.0033395. PubMed: 22438923.
    • (2012) PLOS ONE , vol.7
    • Manaster, I.1    Goldman-Wohl, D.2    Greenfield, C.3    Nachmani, D.4    Tsukerman, P.5
  • 24
    • 79959945255 scopus 로고    scopus 로고
    • Reduction in miR-141 is induced by leukemia inhibitory factor and inhibits proliferation in choriocarcinoma cell line JEG-3
    • doi:10.1111/j.1600-0897.2011.01037.x
    • Morales-Prieto DM, Schleussner E, Markert UR, (2011) Reduction in miR-141 is induced by leukemia inhibitory factor and inhibits proliferation in choriocarcinoma cell line JEG-3. Am J Reprod Immunol 66 (Suppl 1):: 57-62. doi:10.1111/j.1600-0897.2011.01037.x. PubMed: 21726338.
    • (2011) Am J Reprod Immunol , vol.66 , Issue.SUPPL. 1 , pp. 57-62
    • Morales-Prieto, D.M.1    Schleussner, E.2    Markert, U.R.3
  • 25
    • 58449103541 scopus 로고    scopus 로고
    • Expression patterns of microRNAs in the chorioamniotic membranes: a role for microRNAs in human pregnancy and parturition
    • doi:10.1002/path.2463
    • Montenegro D, Romero R, Kim SS, Tarca AL, Draghici S, et al. (2009) Expression patterns of microRNAs in the chorioamniotic membranes: a role for microRNAs in human pregnancy and parturition. J Pathol 217: 113-121. doi:10.1002/path.2463. PubMed: 18991333.
    • (2009) J Pathol , vol.217 , pp. 113-121
    • Montenegro, D.1    Romero, R.2    Kim, S.S.3    Tarca, A.L.4    Draghici, S.5
  • 26
    • 34548476553 scopus 로고    scopus 로고
    • Differential expression of microRNAs with progression of gestation and inflammation in the human chorioamniotic membranes
    • Montenegro D, Romero R, Pineles BL, Tarca AL, Kim YM, et al. (2007) Differential expression of microRNAs with progression of gestation and inflammation in the human chorioamniotic membranes. Am J Obstet Gynecol 197289:: e281-e286. PubMed: 17826424.
    • (2007) Am J Obstet Gynecol , vol.197
    • Montenegro, D.1    Romero, R.2    Pineles, B.L.3    Tarca, A.L.4    Kim, Y.M.5
  • 27
    • 77953540644 scopus 로고    scopus 로고
    • Bisphenol A exposure leads to specific microRNA alterations in placental cells
    • doi:10.1016/j.reprotox.2010.04.004
    • Avissar-Whiting M, Veiga KR, Uhl KM, Maccani MA, Gagne LA, et al. (2010) Bisphenol A exposure leads to specific microRNA alterations in placental cells. Reprod Toxicol 29: 401-406. doi:10.1016/j.reprotox.2010.04.004. PubMed: 20417706.
    • (2010) Reprod Toxicol , vol.29 , pp. 401-406
    • Avissar-Whiting, M.1    Veiga, K.R.2    Uhl, K.M.3    Maccani, M.A.4    Gagne, L.A.5
  • 28
    • 79959435762 scopus 로고    scopus 로고
    • MicroRNA-155 is involved in the remodelling of human-trophoblast-derived HTR-8/SVneo cells induced by lipopolysaccharides
    • doi:10.1093/humrep/der118
    • Dai Y, Diao Z, Sun H, Li R, Qiu Z, et al. (2011) MicroRNA-155 is involved in the remodelling of human-trophoblast-derived HTR-8/SVneo cells induced by lipopolysaccharides. Hum Reprod 26: 1882-1891. doi:10.1093/humrep/der118. PubMed: 21515911.
    • (2011) Hum Reprod , vol.26 , pp. 1882-1891
    • Dai, Y.1    Diao, Z.2    Sun, H.3    Li, R.4    Qiu, Z.5
  • 29
    • 34147116217 scopus 로고    scopus 로고
    • The expression of Argonaute2 and related microRNA biogenesis proteins in normal and hypoxic trophoblasts
    • doi:10.1093/molehr/gam006
    • Donker RB, Mouillet JF, Nelson DM, Sadovsky Y, (2007) The expression of Argonaute2 and related microRNA biogenesis proteins in normal and hypoxic trophoblasts. Mol Hum Reprod 13: 273-279. doi:10.1093/molehr/gam006. PubMed: 17327266.
    • (2007) Mol Hum Reprod , vol.13 , pp. 273-279
    • Donker, R.B.1    Mouillet, J.F.2    Nelson, D.M.3    Sadovsky, Y.4
  • 30
    • 78449244510 scopus 로고    scopus 로고
    • Maternal cigarette smoking during pregnancy is associated with downregulation of miR-16, miR-21, and miR-146a in the placenta
    • doi:10.4161/epi.5.7.12762
    • Maccani MA, Avissar-Whiting M, Banister CE, McGonnigal B, Padbury JF, et al. (2010) Maternal cigarette smoking during pregnancy is associated with downregulation of miR-16, miR-21, and miR-146a in the placenta. Epigenetics 5: 583-589. doi:10.4161/epi.5.7.12762. PubMed: 20647767.
    • (2010) Epigenetics , vol.5 , pp. 583-589
    • Maccani, M.A.1    Avissar-Whiting, M.2    Banister, C.E.3    McGonnigal, B.4    Padbury, J.F.5
  • 31
    • 77953494278 scopus 로고    scopus 로고
    • MiR-205 silences MED1 in hypoxic primary human trophoblasts
    • doi:10.1096/fj.09-149724
    • Mouillet JF, Chu T, Nelson DM, Mishima T, Sadovsky Y, (2010) MiR-205 silences MED1 in hypoxic primary human trophoblasts. FASEB J 24: 2030-2039. doi:10.1096/fj.09-149724. PubMed: 20065103.
    • (2010) FASEB J , vol.24 , pp. 2030-2039
    • Mouillet, J.F.1    Chu, T.2    Nelson, D.M.3    Mishima, T.4    Sadovsky, Y.5
  • 32
    • 33847680037 scopus 로고    scopus 로고
    • Distinct subsets of microRNAs are expressed differentially in the human placentas of patients with preeclampsia
    • Pineles BL, Romero R, Montenegro D, Tarca AL, Han YM, et al. (2007) Distinct subsets of microRNAs are expressed differentially in the human placentas of patients with preeclampsia. Am J Obstet Gynecol 196261:: e261-e266. PubMed: 17346547.
    • (2007) Am J Obstet Gynecol , vol.196
    • Pineles, B.L.1    Romero, R.2    Montenegro, D.3    Tarca, A.L.4    Han, Y.M.5
  • 33
    • 0030772376 scopus 로고    scopus 로고
    • Novel inhibitors of cytokine-induced IkappaBalpha phosphorylation and endothelial cell adhesion molecule expression show anti-inflammatory effects in vivo
    • doi:10.1074/jbc.272.34.21096
    • Pierce JW, Schoenleber R, Jesmok G, Best J, Moore SA, et al. (1997) Novel inhibitors of cytokine-induced IkappaBalpha phosphorylation and endothelial cell adhesion molecule expression show anti-inflammatory effects in vivo. J Biol Chem 272: 21096-21103. doi:10.1074/jbc.272.34.21096. PubMed: 9261113.
    • (1997) J Biol Chem , vol.272 , pp. 21096-21103
    • Pierce, J.W.1    Schoenleber, R.2    Jesmok, G.3    Best, J.4    Moore, S.A.5
  • 34
    • 0037295377 scopus 로고    scopus 로고
    • Discovery of quinazolines as a novel structural class of potent inhibitors of NF-kappa B activation
    • doi:10.1016/S0968-0896(02)00440-6
    • Tobe M, Isobe Y, Tomizawa H, Nagasaki T, Takahashi H, et al. (2003) Discovery of quinazolines as a novel structural class of potent inhibitors of NF-kappa B activation. Bioorg Med Chem 11: 383-391. doi:10.1016/S0968-0896(02)00440-6. PubMed: 12517433.
    • (2003) Bioorg Med Chem , vol.11 , pp. 383-391
    • Tobe, M.1    Isobe, Y.2    Tomizawa, H.3    Nagasaki, T.4    Takahashi, H.5
  • 35
    • 0031897632 scopus 로고    scopus 로고
    • NF-kappa B and Rel proteins: evolutionarily conserved mediators of immune responses
    • doi:10.1146/annurev.immunol.16.1.225
    • Ghosh S, May MJ, Kopp EB, (1998) NF-kappa B and Rel proteins: evolutionarily conserved mediators of immune responses. Annu Rev Immunol 16: 225-260. doi:10.1146/annurev.immunol.16.1.225. PubMed: 9597130.
    • (1998) Annu Rev Immunol , vol.16 , pp. 225-260
    • Ghosh, S.1    May, M.J.2    Kopp, E.B.3
  • 36
    • 17944378526 scopus 로고    scopus 로고
    • Activation by IKKalpha of a second, evolutionary conserved, NF-kappa B signaling pathway
    • doi:10.1126/science.1062677
    • Senftleben U, Cao Y, Xiao G, Greten FR, Krähn G, et al. (2001) Activation by IKKalpha of a second, evolutionary conserved, NF-kappa B signaling pathway. Science 293: 1495-1499. doi:10.1126/science.1062677. PubMed: 11520989.
    • (2001) Science , vol.293 , pp. 1495-1499
    • Senftleben, U.1    Cao, Y.2    Xiao, G.3    Greten, F.R.4    Krähn, G.5
  • 37
    • 0033618630 scopus 로고    scopus 로고
    • Cell activation and apoptosis by bacterial lipoproteins through toll-like receptor-2
    • doi:10.1126/science.285.5428.736
    • Aliprantis AO, Yang RB, Mark MR, Suggett S, Devaux B, et al. (1999) Cell activation and apoptosis by bacterial lipoproteins through toll-like receptor-2. Science 285: 736-739. doi:10.1126/science.285.5428.736. PubMed: 10426996.
    • (1999) Science , vol.285 , pp. 736-739
    • Aliprantis, A.O.1    Yang, R.B.2    Mark, M.R.3    Suggett, S.4    Devaux, B.5
  • 38
    • 34248630818 scopus 로고    scopus 로고
    • Toll-like receptor 2 signaling is a mediator of apoptosis in herpes simplex virus-infected microglia
    • doi:10.1186/1742-2094-4-11
    • Aravalli RN, Hu S, Lokensgard JR, (2007) Toll-like receptor 2 signaling is a mediator of apoptosis in herpes simplex virus-infected microglia. J Neuroinflammation 4: 11. doi:10.1186/1742-2094-4-11. PubMed: 17470292.
    • (2007) J Neuroinflammation , vol.4 , pp. 11
    • Aravalli, R.N.1    Hu, S.2    Lokensgard, J.R.3
  • 39
    • 1642513702 scopus 로고    scopus 로고
    • Stimulation of human Toll-like receptor (TLR) 2 and TLR6 with membrane lipoproteins of Mycoplasma fermentans induces apoptotic cell death after NF-kappa B activation
    • doi:10.1046/j.1462-5822.2003.00356.x
    • Into T, Kiura K, Yasuda M, Kataoka H, Inoue N, et al. (2004) Stimulation of human Toll-like receptor (TLR) 2 and TLR6 with membrane lipoproteins of Mycoplasma fermentans induces apoptotic cell death after NF-kappa B activation. Cell Microbiol 6: 187-199. doi:10.1046/j.1462-5822.2003.00356.x. PubMed: 14706104.
    • (2004) Cell Microbiol , vol.6 , pp. 187-199
    • Into, T.1    Kiura, K.2    Yasuda, M.3    Kataoka, H.4    Inoue, N.5
  • 40
    • 0344643405 scopus 로고    scopus 로고
    • The 19-kDa Mycobacterium tuberculosis protein induces macrophage apoptosis through Toll-like receptor-2
    • López M, Sly LM, Luu Y, Young D, Cooper H, et al. (2003) The 19-kDa Mycobacterium tuberculosis protein induces macrophage apoptosis through Toll-like receptor-2. J Immunol 170: 2409-2416. PubMed: 12594264.
    • (2003) J Immunol , vol.170 , pp. 2409-2416
    • López, M.1    Sly, L.M.2    Luu, Y.3    Young, D.4    Cooper, H.5
  • 41
    • 33645755382 scopus 로고    scopus 로고
    • TLR3 can directly trigger apoptosis in human cancer cells
    • Salaun B, Coste I, Rissoan MC, Lebecque SJ, Renno T, (2006) TLR3 can directly trigger apoptosis in human cancer cells. J Immunol 176: 4894-4901. PubMed: 16585585.
    • (2006) J Immunol , vol.176 , pp. 4894-4901
    • Salaun, B.1    Coste, I.2    Rissoan, M.C.3    Lebecque, S.J.4    Renno, T.5
  • 42
    • 34548384824 scopus 로고    scopus 로고
    • Cell Type-specific Expression and Function of Toll-like Receptors 2 and 4 in Human Placenta: Implications in Fetal Infection
    • doi:10.1016/j.placenta.2007.05.003
    • Ma Y, Krikun G, Abrahams VM, Mor G, Guller S, (2007) Cell Type-specific Expression and Function of Toll-like Receptors 2 and 4 in Human Placenta: Implications in Fetal Infection. Placenta 28: 1024-1031. doi:10.1016/j.placenta.2007.05.003. PubMed: 17588655.
    • (2007) Placenta , vol.28 , pp. 1024-1031
    • Ma, Y.1    Krikun, G.2    Abrahams, V.M.3    Mor, G.4    Guller, S.5
  • 43
    • 0030817061 scopus 로고    scopus 로고
    • Inhibition of NF-kappa B activity induces apoptosis in murine hepatocytes
    • Bellas RE, FitzGerald MJ, Fausto N, Sonenshein GE, (1997) Inhibition of NF-kappa B activity induces apoptosis in murine hepatocytes. Am J Pathol 151: 891-896. PubMed: 9327720.
    • (1997) Am J Pathol , vol.151 , pp. 891-896
    • Bellas, R.E.1    FitzGerald, M.J.2    Fausto, N.3    Sonenshein, G.E.4
  • 44
    • 0034353454 scopus 로고    scopus 로고
    • Inhibition of NF-kappaB activity enhances TRAIL mediated apoptosis in breast cancer cell lines
    • doi:10.1023/A:1006458407515
    • Keane MM, Rubinstein Y, Cuello M, Ettenberg SA, Banerjee P, et al. (2000) Inhibition of NF-kappaB activity enhances TRAIL mediated apoptosis in breast cancer cell lines. Breast Cancer Res Treat 64: 211-219. doi:10.1023/A:1006458407515. PubMed: 11194457.
    • (2000) Breast Cancer Res Treat , vol.64 , pp. 211-219
    • Keane, M.M.1    Rubinstein, Y.2    Cuello, M.3    Ettenberg, S.A.4    Banerjee, P.5
  • 45
    • 0025343895 scopus 로고
    • Activation of interleukin-6 gene expression through the NF-kappa B transcription factor
    • Libermann TA, Baltimore D, (1990) Activation of interleukin-6 gene expression through the NF-kappa B transcription factor. Mol Cell Biol 10: 2327-2334. PubMed: 2183031.
    • (1990) Mol Cell Biol , vol.10 , pp. 2327-2334
    • Libermann, T.A.1    Baltimore, D.2
  • 46
    • 0034601057 scopus 로고    scopus 로고
    • The apoptotic signaling pathway activated by Toll-like receptor-2
    • doi:10.1093/emboj/19.13.3325
    • Aliprantis AO, Yang RB, Weiss DS, Godowski P, Zychlinsky A, (2000) The apoptotic signaling pathway activated by Toll-like receptor-2. EMBO J 19: 3325-3336. doi:10.1093/emboj/19.13.3325. PubMed: 10880445.
    • (2000) EMBO J , vol.19 , pp. 3325-3336
    • Aliprantis, A.O.1    Yang, R.B.2    Weiss, D.S.3    Godowski, P.4    Zychlinsky, A.5
  • 47
    • 84872050193 scopus 로고    scopus 로고
    • Interactions of miR-323/miR-326/miR-329 and miR-130a/miR-155/miR-210 as prognostic indicators for clinical outcome of glioblastoma patients
    • doi:10.1186/1479-5876-11-10
    • Qiu S, Lin S, Hu D, Feng Y, Tan Y, et al. (2013) Interactions of miR-323/miR-326/miR-329 and miR-130a/miR-155/miR-210 as prognostic indicators for clinical outcome of glioblastoma patients. J Transl Med 11: 10. doi:10.1186/1479-5876-11-10. PubMed: 23302469.
    • (2013) J Transl Med , vol.11 , pp. 10
    • Qiu, S.1    Lin, S.2    Hu, D.3    Feng, Y.4    Tan, Y.5
  • 48
    • 77951259728 scopus 로고    scopus 로고
    • MicroRNA as modulators of neuronal responses
    • doi:10.4161/cib.2.5.8834
    • Khudayberdiev S, Fiore R, Schratt G, (2009) MicroRNA as modulators of neuronal responses. Commun Integr Biol 2: 411-413. doi:10.4161/cib.2.5.8834. PubMed: 19907703.
    • (2009) Commun Integr Biol , vol.2 , pp. 411-413
    • Khudayberdiev, S.1    Fiore, R.2    Schratt, G.3
  • 49
    • 77950467511 scopus 로고    scopus 로고
    • MicroRNA expression in human airway smooth muscle cells: role of miR-25 in regulation of airway smooth muscle phenotype
    • doi:10.1165/rcmb.2009-0123OC
    • Kuhn AR, Schlauch K, Lao R, Halayko AJ, Gerthoffer WT, et al. (2010) MicroRNA expression in human airway smooth muscle cells: role of miR-25 in regulation of airway smooth muscle phenotype. Am J Respir Cell Mol Biol 42: 506-513. doi:10.1165/rcmb.2009-0123OC. PubMed: 19541842.
    • (2010) Am J Respir Cell Mol Biol , vol.42 , pp. 506-513
    • Kuhn, A.R.1    Schlauch, K.2    Lao, R.3    Halayko, A.J.4    Gerthoffer, W.T.5
  • 50
    • 79961237509 scopus 로고    scopus 로고
    • MicroRNAs add an additional layer to the complexity of cell signaling
    • Herschkowitz JI, Fu X, (2011) MicroRNAs add an additional layer to the complexity of cell signaling. Sci Signal 4jc5-: jc5 PubMed: 21868350.
    • (2011) Sci Signal , vol.4
    • Herschkowitz, J.I.1    Fu, X.2
  • 51
    • 84863526545 scopus 로고    scopus 로고
    • Stat3-mediated activation of microRNA-23a suppresses gluconeogenesis in hepatocellular carcinoma by down-regulating glucose-6-phosphatase and peroxisome proliferator-activated receptor gamma, coactivator 1 alpha
    • doi:10.1002/hep.25632
    • Wang B, Hsu SH, Frankel W, Ghoshal K, Jacob ST, (2012) Stat3-mediated activation of microRNA-23a suppresses gluconeogenesis in hepatocellular carcinoma by down-regulating glucose-6-phosphatase and peroxisome proliferator-activated receptor gamma, coactivator 1 alpha. Hepatology 56: 186-197. doi:10.1002/hep.25632. PubMed: 22318941.
    • (2012) Hepatology , vol.56 , pp. 186-197
    • Wang, B.1    Hsu, S.H.2    Frankel, W.3    Ghoshal, K.4    Jacob, S.T.5
  • 52
    • 77956311739 scopus 로고    scopus 로고
    • MicroRNA-23a promotes the growth of gastric adenocarcinoma cell line MGC803 and downregulates interleukin-6 receptor
    • doi:10.1111/j.1742-4658.2010.07773.x
    • Zhu LH, Liu T, Tang H, Tian RQ, Su C, et al. (2010) MicroRNA-23a promotes the growth of gastric adenocarcinoma cell line MGC803 and downregulates interleukin-6 receptor. FEBS J 277: 3726-3734. doi:10.1111/j.1742-4658.2010.07773.x. PubMed: 20698883.
    • (2010) FEBS J , vol.277 , pp. 3726-3734
    • Zhu, L.H.1    Liu, T.2    Tang, H.3    Tian, R.Q.4    Su, C.5
  • 53
    • 20044395613 scopus 로고    scopus 로고
    • RAS is regulated by the let-7 microRNA family
    • doi:10.1016/j.cell.2005.01.014
    • Johnson SM, Grosshans H, Shingara J, Byrom M, Jarvis R, et al. (2005) RAS is regulated by the let-7 microRNA family. Cell 120: 635-647. doi:10.1016/j.cell.2005.01.014. PubMed: 15766527.
    • (2005) Cell , vol.120 , pp. 635-647
    • Johnson, S.M.1    Grosshans, H.2    Shingara, J.3    Byrom, M.4    Jarvis, R.5
  • 54
    • 80052502658 scopus 로고    scopus 로고
    • Let-7 microRNA-mediated regulation of IL-13 and allergic airway inflammation
    • doi:10.1016/j.jaci.2011.04.034
    • Kumar M, Ahmad T, Sharma A, Mabalirajan U, Kulshreshtha A, et al. (2011) Let-7 microRNA-mediated regulation of IL-13 and allergic airway inflammation. J Allergy Clin Immunol 128: 1077-1085 e1071-1010 doi:10.1016/j.jaci.2011.04.034. PubMed: 21616524.
    • (2011) J Allergy Clin Immunol , vol.128 , pp. 1077-1085
    • Kumar, M.1    Ahmad, T.2    Sharma, A.3    Mabalirajan, U.4    Kulshreshtha, A.5
  • 55
    • 33947431322 scopus 로고    scopus 로고
    • Disrupting the pairing between let-7 and Hmga2 enhances oncogenic transformation
    • doi:10.1126/science.1137999
    • Mayr C, Hemann MT, Bartel DP, (2007) Disrupting the pairing between let-7 and Hmga2 enhances oncogenic transformation. Science 315: 1576-1579. doi:10.1126/science.1137999. PubMed: 17322030.
    • (2007) Science , vol.315 , pp. 1576-1579
    • Mayr, C.1    Hemann, M.T.2    Bartel, D.P.3
  • 56
    • 70350778443 scopus 로고    scopus 로고
    • An epigenetic switch involving NF-kappaB, Lin28, Let-7 MicroRNA, and IL6 links inflammation to cell transformation
    • doi:10.1016/j.cell.2009.10.014
    • Iliopoulos D, Hirsch HA, Struhl K, (2009) An epigenetic switch involving NF-kappaB, Lin28, Let-7 MicroRNA, and IL6 links inflammation to cell transformation. Cell 139: 693-706. doi:10.1016/j.cell.2009.10.014. PubMed: 19878981.
    • (2009) Cell , vol.139 , pp. 693-706
    • Iliopoulos, D.1    Hirsch, H.A.2    Struhl, K.3
  • 57
    • 84864506367 scopus 로고    scopus 로고
    • Altered let-7 expression in Myasthenia gravis and let-7c mediated regulation of IL-10 by directly targeting IL-10 in Jurkat cells
    • doi:10.1016/j.intimp.2012.07.003
    • Jiang L, Cheng Z, Qiu S, Que Z, Bao W, et al. (2012) Altered let-7 expression in Myasthenia gravis and let-7c mediated regulation of IL-10 by directly targeting IL-10 in Jurkat cells. Int Immunopharmacol 14: 217-223. doi:10.1016/j.intimp.2012.07.003. PubMed: 22835429.
    • (2012) Int Immunopharmacol , vol.14 , pp. 217-223
    • Jiang, L.1    Cheng, Z.2    Qiu, S.3    Que, Z.4    Bao, W.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.