메뉴 건너뛰기




Volumn 31, Issue 5, 2013, Pages 512-519

Triglyceride metabolism in bone tissue is associated with osteoblast and osteoclast differentiation: A gene expression study

Author keywords

Bone tissue; Free fatty acid; Lipogenesis; Lipolysis

Indexed keywords

ADIPONECTIN; FATTY ACID; FATTY ACID SYNTHASE; HORMONE SENSITIVE LIPASE; LIPOPROTEIN LIPASE; OSTEOCLAST DIFFERENTIATION FACTOR; OSTEOPROTEGERIN; TRANSCRIPTION FACTOR RUNX2; TRIACYLGLYCEROL;

EID: 84885430698     PISSN: 09148779     EISSN: 14355604     Source Type: Journal    
DOI: 10.1007/s00774-013-0445-x     Document Type: Article
Times cited : (30)

References (32)
  • 1
    • 80051696196 scopus 로고    scopus 로고
    • Hormone-sensitive lipase-knockout mice maintain high bone density during aging
    • 21566206 10.1096/fj.11-181016 1:CAS:528:DC%2BC3MXpvFersL8%3D
    • Shen WJ, Liu LF, Patel S, Kraemer FB (2011) Hormone-sensitive lipase-knockout mice maintain high bone density during aging. FASEB J 25:2722-2730
    • (2011) FASEB J , vol.25 , pp. 2722-2730
    • Shen, W.J.1    Liu, L.F.2    Patel, S.3    Kraemer, F.B.4
  • 2
    • 84855877835 scopus 로고    scopus 로고
    • Bone marrow fat has brown adipose tissue characteristics, which are attenuated with aging and diabetes
    • Krings A, Rahman S, Huang S, Lu Y, Czernik PJ, Lecka-Czernik B (2011) Bone marrow fat has brown adipose tissue characteristics, which are attenuated with aging and diabetes. Bone 50:546-552
    • (2011) Bone , vol.50 , pp. 546-552
    • Krings, A.1    Rahman, S.2    Huang, S.3    Lu, Y.4    Czernik, P.J.5    Lecka-Czernik, B.6
  • 3
    • 66849106857 scopus 로고    scopus 로고
    • Lipoprotein lipase: From gene to obesity
    • 19318514 10.1152/ajpendo.90920.2008 1:CAS:528:DC%2BD1MXhtVahsbnN
    • Wang H, Eckel RH (2009) Lipoprotein lipase: from gene to obesity. Am J Physiol Endocrinol Metab 297:E271-E288
    • (2009) Am J Physiol Endocrinol Metab , vol.297
    • Wang, H.1    Eckel, R.H.2
  • 4
    • 78650107057 scopus 로고    scopus 로고
    • Lipolysis: A highly regulated multi-enzyme complex mediates the catabolism of cellular fat stores
    • 21087632 10.1016/j.plipres.2010.10.004 1:CAS:528:DC%2BC3cXhs1WktL7N
    • Lass A, Zimmermann R, Oberer M, Zechner R (2011) Lipolysis: a highly regulated multi-enzyme complex mediates the catabolism of cellular fat stores. Prog Lipid Res 50:14-27
    • (2011) Prog Lipid Res , vol.50 , pp. 14-27
    • Lass, A.1    Zimmermann, R.2    Oberer, M.3    Zechner, R.4
  • 5
    • 79952148424 scopus 로고    scopus 로고
    • Biochemistry, molecular biology, and pharmacology of fatty acid synthase, an emerging therapeutic target and diagnosis/prognosis marker
    • 20706604 1:CAS:528:DC%2BC3MXitlOrurg%3D
    • Liu H, Liu JY, Wu X, Zhang JT (2010) Biochemistry, molecular biology, and pharmacology of fatty acid synthase, an emerging therapeutic target and diagnosis/prognosis marker. Int J Biochem Mol Biol 1:69-89
    • (2010) Int J Biochem Mol Biol , vol.1 , pp. 69-89
    • Liu, H.1    Liu, J.Y.2    Wu, X.3    Zhang, J.T.4
  • 6
    • 61949257688 scopus 로고    scopus 로고
    • Saturated with fat: New perspectives on lipotoxicity
    • 19202381 10.1097/MCO.0b013e32832182ee 1:CAS:528:DC%2BD1MXhsFKksLg%3D
    • Garbarino J, Sturley SL (2009) Saturated with fat: new perspectives on lipotoxicity. Curr Opin Clin Nutr Metab Care 12:110-116
    • (2009) Curr Opin Clin Nutr Metab Care , vol.12 , pp. 110-116
    • Garbarino, J.1    Sturley, S.L.2
  • 7
    • 0034033355 scopus 로고    scopus 로고
    • Influence of mature adipocytes on osteoblast proliferation in human primary cocultures
    • 10773588 10.1016/S8756-3282(00)00252-0 1:STN:280:DC%2BD3c3msVensw%3D%3D
    • Maurin A, Chavassieux P, Frappart L, Delmas P, Serre C, Meunier P (2000) Influence of mature adipocytes on osteoblast proliferation in human primary cocultures. Bone 26:485-489
    • (2000) Bone , vol.26 , pp. 485-489
    • Maurin, A.1    Chavassieux, P.2    Frappart, L.3    Delmas, P.4    Serre, C.5    Meunier, P.6
  • 8
    • 0036312826 scopus 로고    scopus 로고
    • Role of polyunsaturated fatty acids in the inhibitory effect of human adipocytes on osteoblastic proliferation
    • 12110443 10.1016/S8756-3282(02)00805-0 1:CAS:528:DC%2BD38XltFWgs7Y%3D
    • Maurin A, Chavassieux P, Vericel E, Meunier P (2002) Role of polyunsaturated fatty acids in the inhibitory effect of human adipocytes on osteoblastic proliferation. Bone 31:260-266
    • (2002) Bone , vol.31 , pp. 260-266
    • Maurin, A.1    Chavassieux, P.2    Vericel, E.3    Meunier, P.4
  • 9
    • 77953948509 scopus 로고    scopus 로고
    • Inhibition of fatty acid biosynthesis prevents adipocyte lipotoxicity on human osteoblasts in vitro
    • Elbaz A, Wu X, Rivas D, Gimble J, Duque G (2009) Inhibition of fatty acid biosynthesis prevents adipocyte lipotoxicity on human osteoblasts in vitro. J Cell Mol Med 14:982-991
    • (2009) J Cell Mol Med , vol.14 , pp. 982-991
    • Elbaz, A.1    Wu, X.2    Rivas, D.3    Gimble, J.4    Duque, G.5
  • 11
    • 77951063837 scopus 로고    scopus 로고
    • Saturated fatty acids enhance osteoclast survival
    • 20388920 10.1194/jlr.M800626 1:CAS:528:DC%2BC3cXltlWksbY%3D
    • Oh SR, Sul OJ, Kim YY, Kim HJ, Yu R, Suh JH, Choi HS (2010) Saturated fatty acids enhance osteoclast survival. J Lipid Res 51:892-899
    • (2010) J Lipid Res , vol.51 , pp. 892-899
    • Oh, S.R.1    Sul, O.J.2    Kim, Y.Y.3    Kim, H.J.4    Yu, R.5    Suh, J.H.6    Choi, H.S.7
  • 12
    • 0033789518 scopus 로고    scopus 로고
    • Adipose tissue as an endocrine organ
    • 10996528 10.1016/S1043-2760(00)00301-5 1:CAS:528:DC%2BD3cXmtlGlsbs%3D
    • Ahima RS, Flier JS (2000) Adipose tissue as an endocrine organ. Trends Endocrinol Metab 11:327-332
    • (2000) Trends Endocrinol Metab , vol.11 , pp. 327-332
    • Ahima, R.S.1    Flier, J.S.2
  • 15
    • 23944517324 scopus 로고    scopus 로고
    • Adiponectin stimulates human osteoblasts proliferation and differentiation via the MAPK signaling pathway
    • 15963981 10.1016/j.yexcr.2005.05.021 1:CAS:528:DC%2BD2MXpt1ekurw%3D
    • Luo X, Guo L, Yuan L, Xie H, Zhou H, Wu X, Liao E (2005) Adiponectin stimulates human osteoblasts proliferation and differentiation via the MAPK signaling pathway. Exp Cell Res 309:99-109
    • (2005) Exp Cell Res , vol.309 , pp. 99-109
    • Luo, X.1    Guo, L.2    Yuan, L.3    Xie, H.4    Zhou, H.5    Wu, X.6    Liao, E.7
  • 17
    • 38649123699 scopus 로고    scopus 로고
    • Adiponectin inhibits induction of TNF-alpha/RANKL-stimulated NFATc1 via the AMPK signaling
    • 18201570 10.1016/j.febslet.2007.12.037 1:CAS:528:DC%2BD1cXhsVeksbk%3D
    • Yamaguchi N, Kukita T, Li YJ, Kamio N, Fukumoto S, Nonaka K, Ninomiya Y, Hanazawa S, Yamashita Y (2008) Adiponectin inhibits induction of TNF-alpha/RANKL-stimulated NFATc1 via the AMPK signaling. FEBS Lett 582:451-456
    • (2008) FEBS Lett , vol.582 , pp. 451-456
    • Yamaguchi, N.1    Kukita, T.2    Li, Y.J.3    Kamio, N.4    Fukumoto, S.5    Nonaka, K.6    Ninomiya, Y.7    Hanazawa, S.8    Yamashita, Y.9
  • 19
    • 79953310334 scopus 로고    scopus 로고
    • Adiponectin inhibits osteoclastogenesis and bone resorption via APPL1-mediated suppression of Akt1
    • 21300805 10.1074/jbc.M110.152405 1:CAS:528:DC%2BC3MXktVOjsrY%3D
    • Tu Q, Zhang J, Dong LQ, Saunders E, Luo E, Tang J, Chen J (2011) Adiponectin inhibits osteoclastogenesis and bone resorption via APPL1-mediated suppression of Akt1. J Biol Chem 286:12542-12553
    • (2011) J Biol Chem , vol.286 , pp. 12542-12553
    • Tu, Q.1    Zhang, J.2    Dong, L.Q.3    Saunders, E.4    Luo, E.5    Tang, J.6    Chen, J.7
  • 20
    • 33749244468 scopus 로고    scopus 로고
    • Adiponectin stimulates RANKL and inhibits OPG expression in human osteoblasts through the MAPK signaling pathway
    • 16995820 10.1359/jbmr.060707 1:CAS:528:DC%2BD28XhtFekt73M
    • Luo X, Guo L, Xie H, Yuan L, Wu X, Zhou H, Liao E (2006) Adiponectin stimulates RANKL and inhibits OPG expression in human osteoblasts through the MAPK signaling pathway. J Bone Miner Res 21:1648-1656
    • (2006) J Bone Miner Res , vol.21 , pp. 1648-1656
    • Luo, X.1    Guo, L.2    Xie, H.3    Yuan, L.4    Wu, X.5    Zhou, H.6    Liao, E.7
  • 21
    • 80052527615 scopus 로고    scopus 로고
    • Influence of adipokines and ghrelin on bone mineral density and fracture risk: A systematic review and meta-analysis
    • 21778223 10.1210/jc.2011-0047 1:CAS:528:DC%2BC3MXht1SktL7I
    • Biver E, Salliot C, Combescure C, Gossec L, Hardouin P, Legroux-Gerot I, Cortet B (2011) Influence of adipokines and ghrelin on bone mineral density and fracture risk: a systematic review and meta-analysis. J Clin Endocrinol Metab 96:2703-2713
    • (2011) J Clin Endocrinol Metab , vol.96 , pp. 2703-2713
    • Biver, E.1    Salliot, C.2    Combescure, C.3    Gossec, L.4    Hardouin, P.5    Legroux-Gerot, I.6    Cortet, B.7
  • 23
    • 0030237445 scopus 로고    scopus 로고
    • Inverse relationship osteoarthritis-osteoporosis: What is the evidence? What are the consequences?
    • 8810662 10.1093/rheumatology/35.9.813 1:STN:280:DyaK28vgs1GntQ%3D%3D
    • Dequeker J, Boonen S, Aerssens J, Westhovens R (1996) Inverse relationship osteoarthritis-osteoporosis: what is the evidence? What are the consequences? Br J Rheumatol 35:813-818
    • (1996) Br J Rheumatol , vol.35 , pp. 813-818
    • Dequeker, J.1    Boonen, S.2    Aerssens, J.3    Westhovens, R.4
  • 24
    • 63949086875 scopus 로고    scopus 로고
    • Osteoarthritis and risk of fractures
    • 19234808 10.1007/s00223-009-9224-z 1:CAS:528:DC%2BD1MXjvVWrtrk%3D
    • Vestergaard P, Rejnmark L, Mosekilde L (2009) Osteoarthritis and risk of fractures. Calcif Tissue Int 84:249-256
    • (2009) Calcif Tissue Int , vol.84 , pp. 249-256
    • Vestergaard, P.1    Rejnmark, L.2    Mosekilde, L.3
  • 25
    • 80052763526 scopus 로고    scopus 로고
    • Osteoblastogenesis and adipogenesis are higher in osteoarthritic than in osteoporotic bone tissue
    • 21854818 10.1016/j.arcmed.2011.08.005 1:CAS:528:DC%2BC3MXhtFGnsb3I
    • Dragojevic J, Logar DB, Komadina R, Marc J (2011) Osteoblastogenesis and adipogenesis are higher in osteoarthritic than in osteoporotic bone tissue. Arch Med Res 42:392-397
    • (2011) Arch Med Res , vol.42 , pp. 392-397
    • Dragojevic, J.1    Logar, D.B.2    Komadina, R.3    Marc, J.4
  • 26
    • 58149307466 scopus 로고    scopus 로고
    • Quantprime: A flexible tool for reliable high-throughput primer design for quantitative pcr
    • 10.1186/1471-2105-9-465
    • Arvidsson S, Kwasniewski M, Riano-Pachon DM, Mueller-Roeber B (2008) Quantprime: a flexible tool for reliable high-throughput primer design for quantitative pcr. BMC Bioinf 9:465
    • (2008) BMC Bioinf , vol.9 , pp. 465
    • Arvidsson, S.1    Kwasniewski, M.2    Riano-Pachon, D.M.3    Mueller-Roeber, B.4
  • 28
    • 42749092987 scopus 로고    scopus 로고
    • Transcription factors controlling osteoblastogenesis
    • 18331818 10.1016/j.abb.2008.02.030 1:CAS:528:DC%2BD1cXlsFOgurg%3D
    • Marie P (2008) Transcription factors controlling osteoblastogenesis. Arch Biochem Biophys 473:98-105
    • (2008) Arch Biochem Biophys , vol.473 , pp. 98-105
    • Marie, P.1
  • 29
    • 42749083246 scopus 로고    scopus 로고
    • Functions of RANKL/RANK/OPG in bone modeling and remodeling
    • 18395508 10.1016/j.abb.2008.03.018 1:CAS:528:DC%2BD1cXlsFOgt7c%3D
    • Boyce BF, Xing L (2008) Functions of RANKL/RANK/OPG in bone modeling and remodeling. Arch Biochem Biophys 473:139-146
    • (2008) Arch Biochem Biophys , vol.473 , pp. 139-146
    • Boyce, B.F.1    Xing, L.2
  • 30
    • 0034996687 scopus 로고    scopus 로고
    • The ratio of messenger rna levels of receptor activator of nuclear factor kappab ligand to osteoprotegerin correlates with bone remodeling indices in normal human cancellous bone but not in osteoarthritis
    • 11393778 10.1359/jbmr.2001.16.6.1015 1:CAS:528:DC%2BD3MXkt1Oqsrw%3D
    • Fazzalari NL, Kuliwaba JS, Atkins GJ, Forwood MR, Findlay DM (2001) The ratio of messenger rna levels of receptor activator of nuclear factor kappab ligand to osteoprotegerin correlates with bone remodeling indices in normal human cancellous bone but not in osteoarthritis. J Bone Miner Res 16:1015-1027
    • (2001) J Bone Miner Res , vol.16 , pp. 1015-1027
    • Fazzalari, N.L.1    Kuliwaba, J.S.2    Atkins, G.J.3    Forwood, M.R.4    Findlay, D.M.5
  • 31
    • 2942739081 scopus 로고    scopus 로고
    • Increased expression of IL-6 and RANK mRNA in human trabecular bone from fragility fracture of the femoral neck
    • 15207775 10.1016/j.bone.2004.02.006 1:CAS:528:DC%2BD2cXltVGjsLs%3D
    • Tsangari H, Findlay DM, Kuliwaba JS, Atkins GJ, Fazzalari NL (2004) Increased expression of IL-6 and RANK mRNA in human trabecular bone from fragility fracture of the femoral neck. Bone 35:334-342
    • (2004) Bone , vol.35 , pp. 334-342
    • Tsangari, H.1    Findlay, D.M.2    Kuliwaba, J.S.3    Atkins, G.J.4    Fazzalari, N.L.5
  • 32
    • 18444365892 scopus 로고    scopus 로고
    • Increased RANKL/OPG mRNA ratio in iliac bone biopsies from women with hip fractures
    • 15570403 10.1007/s00223-004-0074-4 1:CAS:528:DC%2BD2MXivVaitbc%3D
    • Abdallah BM, Stilgren LS, Nissen N, Kassem M, Jorgensen HR, Abrahamsen B (2005) Increased RANKL/OPG mRNA ratio in iliac bone biopsies from women with hip fractures. Calcif Tissue Int 76:90-97
    • (2005) Calcif Tissue Int , vol.76 , pp. 90-97
    • Abdallah, B.M.1    Stilgren, L.S.2    Nissen, N.3    Kassem, M.4    Jorgensen, H.R.5    Abrahamsen, B.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.