APRIL depletion induces cell cycle arrest and apoptosis through blocking TGF-β1/ERK signaling pathway in human colorectal cancer cells

Molecular and Cellular Biochemistry

Volumn 383, Issue 1-2, 2013, Pages 179-189

  Wang, Feng ^a   Chen, Lin ^b   Ni, Hongbin ^a   Wang, Guihua ^a   Ding, Weifeng ^a   Cong, Hui ^a   Ju, Shaoqing ^a   Yang, Shumei ^a   Wang, Huimin ^a  

^a NANTONG UNIVERSITY   (China)

^b Third People's Hospital of Nantong   (China)

Author keywords

Apoptosis; APRIL; Cell cycle; Colorectal carcinoma; RNA interference; TGF 1

Indexed keywords

APRIL PROTEIN; CHOLECYSTOKININ OCTAPEPTIDE; CYCLIN D1; CYCLIN DEPENDENT KINASE 2; MESSENGER RNA; MITOGEN ACTIVATED PROTEIN KINASE; PROTEIN BAX; PROTEIN BCL 2; PROTEIN P21; SMAD2 PROTEIN; SMAD3 PROTEIN; SMALL INTERFERING RNA; TRANSFORMING GROWTH FACTOR BETA1;

ADULT; AGED; APOPTOSIS; ARTICLE; ASSAY; CANCER CELL CULTURE; CELL CYCLE; CELL CYCLE ARREST; CELL GROWTH; CELL PROLIFERATION; CELL VIABILITY; CLINICAL ARTICLE; COLORECTAL CANCER; CONTROLLED STUDY; ENZYME ACTIVATION; FLOW CYTOMETRY; HUMAN; HUMAN CELL; HUMAN TISSUE; IMMUNOHISTOCHEMISTRY; PROTEIN EXPRESSION; REAL TIME POLYMERASE CHAIN REACTION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; RNA INTERFERENCE; SIGNAL TRANSDUCTION; WESTERN BLOTTING;

AGED; APOPTOSIS; CELL CYCLE CHECKPOINTS; CELL LINE, TUMOR; CELL PROLIFERATION; CELL SURVIVAL; COLORECTAL NEOPLASMS; GENE EXPRESSION REGULATION, NEOPLASTIC; GENE SILENCING; HUMANS; MAP KINASE SIGNALING SYSTEM; MIDDLE AGED; RNA, MESSENGER; TRANSFECTION; TRANSFORMING GROWTH FACTOR BETA1; TUMOR NECROSIS FACTOR LIGAND SUPERFAMILY MEMBER 13;

EID: 84885419280     PISSN: 03008177     EISSN: 15734919     Source Type: Journal    
DOI: 10.1007/s11010-013-1766-8     Document Type: Article

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