p53-Mediated Biliary Defects Caused by Knockdown of cirh1a, the Zebrafish Homolog of the Gene Responsible for North American Indian Childhood Cirrhosis

PLoS ONE

Volumn 8, Issue 10, 2013, Pages

  Wilkins, Benjamin J ^a   Lorent, Kristin ^b   Matthews, Randolph P ^a   Pack, Michael ^b  

^a CHILDREN S HOSPITAL OF PHILADELPHIA   (United States)

^b UNIVERSITY OF PENNSYLVANIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

MESSENGER RNA; MORPHOLINO OLIGONUCLEOTIDE; PROTEIN P53;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; APOPTOSIS; ARTICLE; BILIARY TRACT DISEASE; BIOGENESIS; CELL CYCLE ARREST; CELL NUCLEUS; CELL STRESS; CIRH1A GENE; CONTROLLED STUDY; EMBRYO; EPITHELIUM CELL; GENE; GENE EXPRESSION; GENE SILENCING; GENETIC ANALYSIS; GENETIC ASSOCIATION; INDIAN CHILDHOOD CIRRHOSIS; LIVER CELL; LOSS OF FUNCTION MUTATION; MOLECULAR PATHOLOGY; NONHUMAN; NUCLEOLUS; NUCLEOTIDE SEQUENCE; PROTEIN AGGREGATION; PROTEIN DEFICIENCY; REPORTER GENE; RIBOSOME; SEQUENCE HOMOLOGY; UPREGULATION; ZEBRA FISH;

ANIMALS; HEPATOCYTES; HUMANS; IN SITU HYBRIDIZATION; LARVA; LIVER; LIVER CIRRHOSIS, BILIARY; MUTATION; MUTATION, MISSENSE; RIBONUCLEOPROTEINS; TUMOR SUPPRESSOR PROTEIN P53; ZEBRAFISH; ZEBRAFISH PROTEINS;

EID: 84885412567     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0077670     Document Type: Article

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