Targeted Deletion of FGL2 Leads to Increased Early Viral Replication and Enhanced Adaptive Immunity in a Murine Model of Acute Viral Hepatitis Caused by LCMV WE

PLoS ONE

Volumn 8, Issue 10, 2013, Pages

  Khattar, Ramzi ^a   Luft, Olga ^a   Yavorska, Nataliya ^a   Shalev, Itay ^a   Phillips, M James ^a   Adeyi, Oyedele ^a   Gao, Darrin ^a   Bartczak, Agata ^a   Urbanellis, Peter ^a   Shyu, Wendy ^a   Zhang, Jianhua ^a   Manuel, Justin ^a   Levy, Gary A ^a   Selzner, Nazia ^a  

^a UNIVERSITY OF TORONTO   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

ALANINE AMINOTRANSFERASE; B7 ANTIGEN; FIBRINOGEN LIKE PROTEIN 2; GAMMA INTERFERON; MAJOR HISTOCOMPATIBILITY ANTIGEN CLASS 2; NEUTRALIZING ANTIBODY; REGULATOR PROTEIN; UNCLASSIFIED DRUG; VIRUS ANTIBODY;

ADAPTIVE IMMUNITY; ALANINE AMINOTRANSFERASE BLOOD LEVEL; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANTIBODY TITER; ARTICLE; CD4+ T LYMPHOCYTE; CD8+ T LYMPHOCYTE; CONTROLLED STUDY; CYTOKINE PRODUCTION; DENDRITIC CELL; EX VIVO STUDY; FEMALE; FGL2 GENE; GENE DELETION; GENE TARGETING; INFLAMMATION; LIVER; LIVER NECROSIS; LYMPH NODE; LYMPHOCYTIC CHORIOMENINGITIS VIRUS; MOUSE; NONHUMAN; PROTEIN BLOOD LEVEL; PROTEIN EXPRESSION; SPLEEN; VIRAL CLEARANCE; VIRUS HEPATITIS; VIRUS IMMUNITY; VIRUS LOAD; VIRUS REPLICATION;

ADAPTIVE IMMUNITY; ALANINE TRANSAMINASE; ANIMALS; ANTIBODIES, NEUTRALIZING; ANTIGENS, CD80; B-LYMPHOCYTES; CD4-POSITIVE T-LYMPHOCYTES; CD8-POSITIVE T-LYMPHOCYTES; DENDRITIC CELLS; FEMALE; FIBRINOGEN; GENE DELETION; GENE EXPRESSION REGULATION; HEPATITIS; HOST-PATHOGEN INTERACTIONS; INTERFERON-GAMMA; LYMPHOCYTIC CHORIOMENINGITIS VIRUS; MICE; MICE, KNOCKOUT; SIGNAL TRANSDUCTION; SPLEEN; VIRAL LOAD; VIRUS REPLICATION;

EID: 84885411102     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0072309     Document Type: Article

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