Functionalized liposomes loaded with siRNAs targeting ion channels in effector memory T cells as a potential therapy for autoimmunity

Biomaterials

Volumn 34, Issue 38, 2013, Pages 10249-10257

  Hajdu, Péter ^a   Chimote, Ameet A ^a   Thompson, Tyler H ^a   Koo, Youngmi ^b   Yun, Yeoheung ^b   Conforti, Laura ^a  

^a UNIVERSITY OF CINCINNATI COLLEGE OF MEDICINE   (United States)

^b North Carolina Agricultural and Technical State University   (United States)

Author keywords

Autoimmunity; Kv1.3 ion channel; Lipid nanoparticles; SiRNA; T cell

Indexed keywords

AUTOIMMUNE DISORDER; AUTOIMMUNITY; CELL SURFACE MARKER; ION CHANNEL; LIPID NANOPARTICLES; PHOSPHATIDYLCHOLINE; POTENTIAL THERAPIES; SIRNA;

CALCIUM; CELL MEMBRANES; DISEASE CONTROL; IONS; LIPOSOMES; MOLECULAR BIOLOGY; NANOPARTICLES; PROTEINS; RNA; SYNTHESIS (CHEMICAL); T-CELLS;

CYTOLOGY;

CHOLESTEROL; LIPOSOME; PHOSPHATIDYLCHOLINE; PHOSPHOETHANOLAMINE; POTASSIUM CHANNEL KV1.3; SMALL INTERFERING RNA; SOLID LIPID NANOPARTICLE; STREPTAVIDIN;

ARTICLE; AUTOIMMUNITY; CALCIUM TRANSPORT; CONTROLLED STUDY; CYTOSOL; EFFECTOR CELL; ENDOCYTOSIS; FREEZE DRYING; GENE SILENCING; HUMAN; HUMAN CELL; INTERNALIZATION; LIGHT SCATTERING; MEMORY T LYMPHOCYTE; NANOENCAPSULATION; PRIORITY JOURNAL; SURFACE PROPERTY; SYNTHESIS;

AUTOIMMUNITY; KV1.3 ION CHANNEL; LIPID NANOPARTICLES; SIRNA; T CELL;

AUTOIMMUNITY; CELLS, CULTURED; ELECTROPHYSIOLOGY; HUMANS; IMMUNOHISTOCHEMISTRY; LIPOSOMES; MICROSCOPY, CONFOCAL; RNA, SMALL INTERFERING; T-LYMPHOCYTES;

EID: 84885388963     PISSN: 01429612     EISSN: 18785905     Source Type: Journal    
DOI: 10.1016/j.biomaterials.2013.09.019     Document Type: Article

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