The relationship between mental and physical health: Insights from the study of heart rate variability

International Journal of Psychophysiology

Volumn 89, Issue 3, 2013, Pages 288-296

  Kemp, Andrew H ^a,b   Quintana, Daniel S ^a  

^a UNIVERSITY OF SYDNEY   (Australia)

^b UNIVERSITY OF SÃO PAULO   (Brazil)

Author keywords

Alcohol dependence; Anxiety; Cardiovascular disease; Cardiovascular risk reduction; Depression; Heart rate variability; Mortality; Pharmacological treatment; Psychological treatment

Indexed keywords

C REACTIVE PROTEIN; CITALOPRAM; HIGH DENSITY LIPOPROTEIN CHOLESTEROL; INTERLEUKIN 1; INTERLEUKIN 6; LOW DENSITY LIPOPROTEIN CHOLESTEROL; MIRTAZAPINE; NEFAZODONE; SEROTONIN NORADRENALIN REUPTAKE INHIBITOR; SEROTONIN UPTAKE INHIBITOR; SERTRALINE; TRICYCLIC ANTIDEPRESSANT AGENT;

ALCOHOLISM; ANXIETY DISORDER; AUTONOMIC NERVOUS SYSTEM FUNCTION; AUTOREGULATION; CARDIOVASCULAR DISEASE; CARDIOVASCULAR EFFECT; CARDIOVASCULAR MORTALITY; CARDIOVASCULAR RISK; DOWN REGULATION; ELECTROCONVULSIVE THERAPY; EXECUTIVE FUNCTION; FOLLOW UP; FRAMINGHAM RISK SCORE; HEART RATE VARIABILITY; HUMAN; META ANALYSIS (TOPIC); MOOD; MOTIVATION; PHYSIOLOGICAL PROCESS; PSYCHOLOGICAL BALANCE; PSYCHOLOGICAL WELL BEING; QT PROLONGATION; REVIEW; SOCIAL BEHAVIOR; SOCIAL COGNITION; SOCIAL SUPPORT; SUDDEN CARDIAC DEATH; TRANSCRANIAL MAGNETIC STIMULATION; WELLBEING;

ALCOHOL DEPENDENCE; ANXIETY; CARDIOVASCULAR DISEASE; CARDIOVASCULAR RISK REDUCTION; DEPRESSION; HEART RATE VARIABILITY; MORTALITY; PHARMACOLOGICAL TREATMENT; PSYCHOLOGICAL TREATMENT;

ALCOHOLISM; AUTONOMIC NERVOUS SYSTEM DISEASES; COMORBIDITY; HEART RATE; HUMANS; MOOD DISORDERS;

EID: 84885370666     PISSN: 01678760     EISSN: 18727697     Source Type: Journal    
DOI: 10.1016/j.ijpsycho.2013.06.018     Document Type: Review

References (116)

1. Appelhans B., Luecken L. Heart rate variability as an index of regulated emotional responding. Review of General Psychology 2006, 10:229-240.
2. Aquino E.M.L., Barreto S.M., Benseñor I.M., Carvalho M.S., Chor D., Duncan B.B., Lotufo P.A., Mill J.G., Molina M.D.C., Mota E.L.A., Azeredo Passos V.M., Schmidt M.I., Szklo M. Brazilian Longitudinal Study of Adult Health (ELSA-Brasil): objectives and design. American Journal of Epidemiology 2012, 175:315-324.
3. Bal E., Harden E., Lamb D., Van Hecke A.V., Denver J.W., Porges S.W. Emotion recognition in children with autism spectrum disorders: relations to eye gaze and autonomic state. Journal of Autism and Developmental Disorders 2010, 40:358-370.
4. Beauchaine T.P., Gatzke-Kopp L., Mead H.K. Polyvagal theory and developmental psychopathology: emotion dysregulation and conduct problems from preschool to adolescence. Biological Psychology 2007, 74:174-184.
5. Berger S., Boettger M.K., Tancer M., Guinjoan S.M., Yeragani V.K., Bar K.J. Reduced cardio-respiratory coupling indicates suppression of vagal activity in healthy relatives of patients with schizophrenia. Progress in Neuro-Psychopharmacology & Biological Psychiatry 2010, 34:406-411.
6. Bigger J.T., Fleiss J.L., Steinman R.C., Rolnitzky L.M., Kleiger R.E., Rottman J.N. Frequency domain measures of heart period variability and mortality after myocardial infarction. Circulation 1992, 85:164-171.
7. Bigger J.T., Fleiss J.L., Rolnitzky L.M., Steinman R.C. Frequency domain measures of heart period variability to assess risk late after myocardial infarction. Journal of the American College of Cardiology 1993, 21:729-736.
8. Bloom D.E., Cafiero E., Jané-Llopis E., Abrahams-Gessel S., Bloom L.R., Fathima S., Feigl A.B., Gaziano T., Hamandi A., Mowafi M. The Global Economic Burden of Noncommunicable Diseases 2011, World Economic Forum and the Harvard School of Public Health, Geneva.
9. Boehm J.K., Kubzansky L.D. The heart's content: the association between positive psychological well-being and cardiovascular health. Psychological Bulletin 2012, 138:655-691.
10. Boschloo L., Vogelzangs N., Licht C.M., Vreeburg S.A., Smit J.H., van den Brink W., Veltman D.J., de Geus E.J., Beekman A.T., Penninx B.W. Heavy alcohol use, rather than alcohol dependence, is associated with dysregulation of the hypothalamic-pituitary-adrenal axis and the autonomic nervous system. Drug and Alcohol Dependence 2011, 116:170-176.
11. Buchhorn R., Conzelmann A., Willaschek C., Stork D., Taurines R., Renner T.J. Heart rate variability and methylphenidate in children with ADHD. Attention Deficit and Hyperactivity Disorders 2012, 4:85-91.
12. Carney R.M., Freedland K.E. Depression and heart rate variability in patients with coronary heart disease. Cleveland Clinic Journal of Medicine 2009, 76:S13-S17.
13. Carney R.M., Freedland K.E., Stein P.K., Skala J.A., Hoffman P., Jaffe A.S. Change in heart rate and heart rate variability during treatment for depression in patients with coronary heart disease. Psychosomatic Medicine 2000, 62:639-647.
14. Carney R.M., Blumenthal J.A., Freedland K.E., Stein P.K., Howells W.B., Berkman L.F., Watkins L.L., Czajkowski S.M., Hayano J., Domitrovich P.P., Jaffe A.S. Low heart rate variability and the effect of depression on post-myocardial infarction mortality. Archives of Internal Medicine 2005, 165:1486-1491.
15. Cherry D., Woodwell D., Rechsteiner E. National Ambulatory Medical Care Survey: 2005 summary. Advance Data From Vital and Health Statistics; No. 387 2007, National Center for Health Statistics, Hyattsville, MD.
16. Dantzer R., O'Connor J.C., Freund G.G., Johnson R.W., Kelley K.W. From inflammation to sickness and depression: when the immune system subjugates the brain. Nature Reviews Neuroscience 2008, 9:46-56.
17. Dekker J.M., Crow R.S., Folsom A.R., Hannan P.J., Liao D., Swenne C.A., Schouten E.G. Low heart rate variability in a 2-minute rhythm strip predicts risk of coronary heart disease and mortality from several causes: the ARIC Study. Atherosclerosis Risk In Communities. Circulation 2000, 102:1239-1244.
18. Di Simplicio M., Costoloni G., Western D., Hanson B., Taggart P., Harmer C.J. Decreased heart rate variability during emotion regulation in subjects at risk for psychopathology. Psychological Medicine 2012, 42:1775-1783.
19. Dubois C.M., Beach S.R., Kashdan T.B., Nyer M.B., Park E.R., Celano C.M., Huffman J.C. Positive psychological attributes and cardiac outcomes: associations, mechanisms, and interventions. Psychosomatics 2012, 53:303-318.
20. FDA FDA Drug Safety Communication: Abnormal Heart Rhythms Associated with High Doses of Celexa (Citalopram Hydrobromide) http://www.fda.gov/Drugs/DrugSafety/ucm269086.htm.
21. Friedman B.H. An autonomic flexibility-neurovisceral integration model of anxiety and cardiac vagal tone. Biological Psychology 2007, 74:185-199.
22. Garakani A., Martinez J.M., Aaronson C.J., Voustianiouk A., Kaufmann H., Gorman J.M. Effect of medication and psychotherapy on heart rate variability in panic disorder. Depression and Anxiety 2009, 26:251-258.
23. Geisler F.C.M., Vennewald N., Kubiak T., Weber H. The impact of heart rate variability on subjective well-being is mediated by emotion regulation. Personality and Individual Differences 2010, 49:723-728.
24. Geisler F.C., Kubiak T., Siewert K., Weber H. Cardiac vagal tone is associated with social engagement and self-regulation. Biological Psychology 2013, 93:279-286.
25. Glassman A., Maj M., Sartorius N. Depression and Heart Disease 2010, John Wiley & Sons Ltd., Chichester, UK.
26. Goodwin R.D. Association between physical activity and mental disorders among adults in the United States. Preventive Medicine 2003, 36:698-703.
27. Hamer M., Batty G.D., Seldenrijk A., Kivimaki M. Antidepressant medication use and future risk of cardiovascular disease: the Scottish Health Survey. European Heart Journal 2010.
28. Hamer M., Batty G., Marmot M.G., Singh-Manoux A., Kivimaki M. Anti-depressant medication use and C-reactive protein: results from two population-based studies. Brain, Behavior, and Immunity 2011, 25:168-173.
29. Hansen A.L., Johnsen B.H., Thayer J.F. Vagal influence on working memory and attention. International Journal of Psychophysiology 2003, 48:263-274.
30. Henry B.L., Minassian A., Paulus M.P., Geyer M.A., Perry W. Heart rate variability in bipolar mania and schizophrenia. Journal of Psychiatric Research 2010, 44:168-176.
31. Huston J.M., Tracey K.J. The pulse of inflammation: heart rate variability, the cholinergic anti-inflammatory pathway and implications for therapy. Journal of Internal Medicine 2011, 269:45-53.
32. Jane-Llopis E., Matytsina I. Mental health and alcohol, drugs and tobacco: a review of the comorbidity between mental disorders and the use of alcohol, tobacco and illicit drugs. Drug and Alcohol Review 2006, 25:515-536.
33. Karavidas M.K., Lehrer P.M., Vaschillo E., Vaschillo B., Marin H., Buyske S., Malinovsky I., Radvanski D., Hassett A. Preliminary results of an open label study of heart rate variability biofeedback for the treatment of major depression. Applied Psychophysiology and Biofeedback 2007, 32:19-30.
34. Kashdan T.B., Rottenberg J. Psychological flexibility as a fundamental aspect of health. Clinical Psychology Review 2010, 30:865-878.
35. Katon W., Maj M., Sartorius N. Depression and Diabetes 2011, John Wiley & Sons Ltd., Chichester, UK.
36. Kemp A. Depression, antidepressant treatment and the cardiovascular system. Acta Neuropsychiatrica 2011, 23:82-83.
37. Kemp A.H. Reply to: Are antidepressants good for the soul but bad for the matter? Using noninvasive brain stimulation to detangle depression/antidepressants effects on heart rate variability and cardiovascular risk. Biological Psychiatry 2012.
38. Kemp A.H., Quintana D.S., Gray M.A., Felmingham K.L., Brown K., Gatt J.M. Impact of depression and antidepressant treatment on heart rate variability: a review and meta-analysis. Biological Psychiatry 2010, 67:1067-1074.
39. Kemp A.H., Quintana D.S., Gray M.A. Is heart rate variability reduced in depression without cardiovascular disease. BPS 2011, 69:3-4.
40. Kemp A.H., Quintana D.S., Malhi G.S. Effects of serotonin reuptake inhibitors on heart rate variability: methodological issues, medical comorbidity, and clinical relevance. Biological Psychiatry 2011, 69:e25-e26. (author reply e27-28).
41. Kemp A.H., Quintana D.S., Felmingham K.L., Matthews S., Jelinek H.F. Depression, comorbid anxiety disorders, and heart rate variability in physically healthy, unmedicated patients: implications for cardiovascular risk. PLoS One 2012, 7:e30777.
42. Kemp A.H., Quintana D.S., Kuhnert R.-L., Griffiths K., Hickie I.B., Guastella A.J. Oxytocin increases heart rate variability in humans at rest: implications for social approach-related motivation and capacity for social engagement. PLoS One 2012, 7:e44014.
43. Kessler R.C., Chiu W.T., Demler O., Merikangas K.R., Walters E.E. Prevalence, severity, and comorbidity of 12-month DSM-IV disorders in the National Comorbidity Survey Replication. Archives of General Psychiatry 2005, 62:617-627.
44. Kissane D., Maj M., Sartorius N. Depression and Cancer 2011, John Wiley & Sons Ltd., Chichester, UK.
45. Kluttig A., Kuss O., Greiser K.H. Ignoring lack of association of heart rate variability with cardiovascular disease and risk factors: response to the manuscript "The relationship of autonomic imbalance, heart rate variability cardiovascular disease risk factors" by Julian F. Thayer, Shelby S. Yamamoto, Jos F. Brosschot. International Journal of Cardiology 2010, 145:375-376.
46. Koskinen T., Kahonen M., Jula A., Mattsson N., Laitinen T., Keltikangas-Jarvinen L., Viikari J., Valimaki I., Ronnemaa T., Raitakari O.T. Metabolic syndrome and short-term heart rate variability in young adults. The cardiovascular risk in young Finns study. Diabetic Medicine 2009, 26:354-361.
47. Lee J.S., Kim B., Hong Y., Joo Y.H. Heart rate variability in the subsyndromal depressive phase of bipolar disorder. Psychiatry and Clinical Neurosciences 2012, 66:361-366.
48. Liao D., Cai J., Barnes R.W., Tyroler H.A., Rautaharju P., Holme I., Heiss G. Association of cardiac autonomic function and the development of hypertension: the ARIC study. American Journal of Hypertension 1996, 9:1147-1156.
49. Licht C.M.M., de Geus E.J.C., Zitman F.G., Hoogendijk W.J.G., van Dyck R., Penninx B.W.J.H. Association between major depressive disorder and heart rate variability in the Netherlands Study of Depression and Anxiety (NESDA). Archives of General Psychiatry 2008, 65:1358-1367.
50. Licht C.M.M., de Geus E.J.C., van Dyck R., Penninx B.W.J.H. Longitudinal evidence for unfavorable effects of antidepressants on heart rate variability. Biological Psychiatry 2010, 68:861-868.
51. Licht C.M.M., Penninx B.W., de Geus E.J.C. To include or not to include? A response to the meta-analysis of heart rate variability and depression. Biological Psychiatry 2011, 69:e1. (author reply e3-4).
52. Licht C.M.M., Penninx B.W.J.H., Geus E.J.C.d Reply to: Effects of serotonin reuptake inhibitors on heart rate variability: methodological issues, medical comorbidity, and clinical relevance. BPS 2011, 1-2.
53. Licht C.M.M., Penninx B.W.J.H., de Geus E.J.C. Effects of antidepressants, but not psychopathology, on cardiac sympathetic control: a longitudinal study. Neuropsychopharmacology: Official Publication of the American College of Neuropsychopharmacology 2012, 1-9.
54. Licht C.M., de Geus E.J., Penninx B.W. Dysregulation of the autonomic nervous system predicts the development of the metabolic syndrome. Journal of Clinical Endocrinology and Metabolism 2013.
55. Lichtman J.H., Bigger J.T., Blumenthal J.A., Frasure-Smith N., Kaufmann P.G., Lespérance F., Mark D.B., Sheps D.S., Taylor C.B., Froelicher E.S., Nursing, A.H.A.P.C.o.t.C.o.C., Cardiology, A.H.A.C.o.C., Prevention, A.H.A.C.o.E.a, Research, A.H.A.I.C.o.Q.o.C.a.O., Association, A.P. Depression and coronary heart disease: recommendations for screening, referral, and treatment: a science advisory from the American Heart Association Prevention Committee of the Council on Cardiovascular Nursing, Council on Clinical Cardiology, Council on Epidemiology and Prevention, and Interdisciplinary Council on Quality of Care and Outcomes Research: endorsed by the American Psychiatric Association. Circulation 2008, 118:1768-1775.
56. Markkula N., Harkanen T., Perala J., Partti K., Pena S., Koskinen S., Lonnqvist J., Suvisaari J., Saarni S.I. Mortality in people with depressive, anxiety and alcohol use disorders in Finland. The British Journal of Psychiatry 2012, 200:143-149.
57. Mathers C.D., Loncar D. Projections of global mortality and burden of disease from 2002 to 2030. PLoS Medicine 2006, 3:e442.
58. Middleton K., Him E., Xu J. National Hospital Ambulatory Medical Care Survey: 2005 Outpatient Department summary. Advance Data From Vital and Health Statistics; No. 389 2007, National Center for Health Statistics, Hyattsville, MD.
59. Minami J., Ishimitsu T., Matsuoka H. Effects of smoking cessation on blood pressure and heart rate variability in habitual smokers. Hypertension 1999, 33:586-590.
60. Nahshoni E., Aizenberg D., Sigler M., Zalsman G., Strasberg B., Imbar S., Weizman A. Heart rate variability in elderly patients before and after electroconvulsive therapy. The American Journal of Geriatric Psychiatry: Official Journal of the American Association for Geriatric Psychiatry 2001, 9:255-260.
61. Nahshoni E., Aizenberg D., Sigler M., Strasberg B., Zalsman G., Imbar S., Adler E., Weizman A. Heart rate variability increases in elderly depressed patients who respond to electroconvulsive therapy. Journal of Psychosomatic Research 2004, 56:89-94.
62. Nemeroff C.B., Goldschmidt-Clermont P.J. Heartache and Heartbreak-The Link Between Depression and Cardiovascular Disease 2012, 9:526-539. Nature Publishing Group.
63. Oveis C., Cohen A.B., Gruber J., Shiota M.N., Haidt J., Keltner D. Resting respiratory sinus arrhythmia is associated with tonic positive emotionality. Emotion (Washington, DC) 2009, 9:265-270.
64. Pan A., Sun Q., Okereke O.I., Rexrode K.M., Hu F.B. Depression and risk of stroke morbidity and mortality: a meta-analysis and systematic review. JAMA: The Journal of the American Medical Association 2011, 306:1241-1249.
65. Park S.K., Tucker K.L., O'Neill M.S., Sparrow D., Vokonas P.S., Hu H., Schwartz J. Fruit, vegetable, and fish consumption and heart rate variability: the Veterans Administration Normative Aging Study. The American Journal of Clinical Nutrition 2009, 89:778-786.
66. Pavlov V.A., Tracey K.J. The vagus nerve and the inflammatory reflex-linking immunity and metabolism. Nature Reviews. Endocrinology 2012, 8:743-754.
67. Phillips A.C., Batty G.D., Gale C.R., Deary I.J., Osborn D., MacIntyre K., Carroll D. Generalized anxiety disorder, major depressive disorder, and their comorbidity as predictors of all-cause and cardiovascular mortality: the Vietnam experience study. Psychosomatic Medicine 2009, 71:395-403.
68. Pizzi C., Rutjes A.W.S., Costa G.M., Fontana F., Mezzetti A., Manzoli L. Meta-analysis of selective serotonin reuptake inhibitors in patients with depression and coronary heart disease. The American Journal of Cardiology 2011, 107:972-979.
69. Porges S.W. Orienting in a defensive world: mammalian modifications of our evolutionary heritage. A polyvagal theory. Psychophysiology 1995, 32:301-318.
70. Porges S.W. Emotion: an evolutionary by-product of the neural regulation of the autonomic nervous system. Annals of the New York Academy of Sciences 1997, 807:62-77.
71. Porges S.W. Love: an emergent property of the mammalian autonomic nervous system. Psychoneuroendocrinology 1998, 23:837-861.
72. Porges S.W. The polyvagal theory: phylogenetic substrates of a social nervous system. International Journal of Psychophysiology: Official Journal of the International Organization of Psychophysiology 2001, 42:123-146.
73. Porges S.W. The polyvagal theory: phylogenetic contributions to social behavior. Physiology & Behavior 2003, 79:503-513.
74. Porges S.W. Social engagement and attachment: a phylogenetic perspective. Annals of the New York Academy of Sciences 2003, 1008:31-47.
75. Porges S.W. The polyvagal perspective. Biological Psychology 2007, 74:116-143.
76. Porges S.W. The polyvagal theory: new insights into adaptive reactions of the autonomic nervous system. Cleveland Clinic Journal of Medicine 2009, 76(Suppl. 2):S86-S90.
77. Porges S.W. The Polyvagal Theory: Neurophysiological Foundations of Emotions, Attachment, Communication, and Self-regulation 2011, W. W. Norton & Company, New York. 1st ed.
78. Quintana D.S., Guastella A.J., Outhred T., Hickie I.B., Kemp A.H. Heart rate variability is associated with emotion recognition: direct evidence for a relationship between the autonomic nervous system and social cognition. International Journal of Psychophysiology 2012, 86:168-172.
79. Quintana D., Guastella A., McGregor I., Hickie I., Kemp A. Heart rate variability predicts alcohol craving in alcohol dependent outpatients: further evidence for HRV as a psychophysiological marker of self-regulation. Drug and Alcohol Dependence 2013, 132:395-398.
80. Quintana D.S., Kemp A.H., Alvares G.A., Guastella A.J. A role for autonomic cardiac control in the effects of oxytocin on social behavior and psychiatric illness. Frontiers in Neuroscience 2013, 7:48.
81. Quintana D.S., McGregor I.S., Guastella A.J., Malhi G.S., Kemp A.H. A meta-analysis on the impact of alcohol dependence on short-term resting-state heart rate variability: implications for cardiovascular risk. Alcoholism, Clinical and Experimental Research 2013, 37:E23-E29.
82. Rehm J., Mathers C., Popova S., Thavorncharoensap M., Teerawattananon Y., Patra J. Global burden of disease and injury and economic cost attributable to alcohol use and alcohol-use disorders. Lancet 2009, 373:2223-2233.
83. Rennie K.L., Hemingway H., Kumari M., Brunner E., Malik M., Marmot M. Effects of moderate and vigorous physical activity on heart rate variability in a British study of civil servants. American Journal of Epidemiology 2003, 158:135-143.
84. Rudisch B., Nemeroff C.B. Epidemiology of comorbid coronary artery disease and depression. Biological Psychiatry 2003, 54:227-240.
85. Ruiz-Padial E., Sollers J.J., Vila J., Thayer J.F. The rhythm of the heart in the blink of an eye: emotion-modulated startle magnitude covaries with heart rate variability. Psychophysiology 2003, 40:306-313.
86. Russ T.C., Stamatakis E., Hamer M., Starr J.M., Kivimaki M., Batty G.D. Association between psychological distress and mortality: individual participant pooled analysis of 10 prospective cohort studies. BMJ 2012, 345:e4933.
87. Schmitz N., Kruse J., Heckrath C., Alberti L., Tress W. Diagnosing mental disorders in primary care: the General Health Questionnaire (GHQ) and the Symptom Check List (SCL-90-R) as screening instruments. Social Psychiatry and Psychiatric Epidemiology 1999, 34:360-366.
88. Schroeder E.B., Liao D., Chambless L.E., Prineas R.J., Evans G.W., Heiss G. Hypertension, blood pressure, and heart rate variability: the Atherosclerosis Risk in Communities (ARIC) study. Hypertension 2003, 42:1106-1111.
89. Soares-Miranda L., Sandercock G., Vale S., Santos R., Abreu S., Moreira C., Mota J. Metabolic syndrome, physical activity and cardiac autonomic function. Diabetes/Metabolism Research and Reviews 2012, 28:363-369.
90. Tang Y., Ma Y., Fan Y., Feng H., WANG J., Feng S., Lu Q., Hu B., Lin Y., Li J. Central and autonomic nervous system interaction is altered by short-term meditation. Proceedings of the National Academy of Sciences 2009, 106:8865-8870.
91. Taylor C.B. Depression, heart rate related variables and cardiovascular disease. International Journal of Psychophysiology: Official Journal of the International Organization of Psychophysiology 2010, 78:80-88.
92. Thayer J.F. Vagal tone and the inflammatory reflex. Cleveland Clinic Journal of Medicine 2009, 76(Suppl. 2):S23-S26.
93. Thayer J.F., Brosschot J.F. Psychosomatics and psychopathology: looking up and down from the brain. Psychoneuroendocrinology 2005, 30:1050-1058.
94. Thayer J.F., Lane R.D. A model of neurovisceral integration in emotion regulation and dysregulation. Journal of Affective Disorders 2000, 61:201-216.
95. Thayer J.F., Lane R.D. The role of vagal function in the risk for cardiovascular disease and mortality. Biological Psychology 2007, 74:224-242.
96. Thayer J.F., Lane R.D. Claude Bernard and the heart-brain connection: further elaboration of a model of neurovisceral integration. Neuroscience and Biobehavioral Reviews 2009, 33:81-88.
97. Thayer J.F., Sternberg E. Beyond heart rate variability: vagal regulation of allostatic systems. Annals of the New York Academy of Sciences 2006, 1088:361-372.
98. Thayer J.F., Hansen A.L., Saus-Rose E., Johnsen B.H. Heart rate variability, prefrontal neural function, and cognitive performance: the neurovisceral integration perspective on self-regulation, adaptation, and health. Annals of Behavioral Medicine 2009, 37:141-153.
99. Thayer J.F., Yamamoto S.S., Brosschot J.F. On the nature of risk factors: a response to Kluttig, Kuss, and Greiser. International Journal of Cardiology 2010, 145:560-561.
100. Thayer J.F., Yamamoto S.S., Brosschot J.F. The relationship of autonomic imbalance, heart rate variability and cardiovascular disease risk factors. International Journal of Cardiology 2010, 141:122-131.
101. Thayer J.F., Ahs F., Fredrikson M., Sollers Iii J.J., Wager T.D. A meta-analysis of heart rate variability and neuroimaging studies: implications for heart rate variability as a marker of stress and health. Neuroscience and Biobehavioral Reviews 2012, 36:747-756.
102. Tracey K. The inflammatory reflex. Nature 2002, 420:853-859.
103. Tracey K.J. Physiology and immunology of the cholinergic antiinflammatory pathway. The Journal of Clinical Investigation 2007, 117:289-296.
104. Tsuji H., Venditti F., Manders E., Evans J., Larson M., Feldman C., Levy D. Reduced heart rate variability and mortality risk in an elderly cohort. The Framingham Heart Study. Circulation 1994, 90:878.
105. Tsuji H., Larson M., Venditti F., Manders E., Evans J., Feldman C., Levy D. Impact of reduced heart rate variability on risk for cardiac events: the Framingham Heart Study. Circulation 1996, 94:2850.
106. Tudor-Locke C., Craig C.L., Brown W.J., Clemes S.A., De Cocker K., Giles-Corti B., Hatano Y., Inoue S., Matsudo S.M., Mutrie N., Oppert J.M., Rowe D.A., Schmidt M.D., Schofield G.M., Spence J.C., Teixeira P.J., Tully M.A., Blair S.N. How many steps/day are enough? For adults. International Journal of Behavioral Nutrition and Physical Activity 2011, 8:79.
107. Udupa K., Sathyaprabha T.N., Thirthalli J., Kishore K.R., Raju T.R., Gangadhar B.N. Modulation of cardiac autonomic functions in patients with major depression treated with repetitive transcranial magnetic stimulation. Journal of Affective Disorders 2007, 104:231-236.
108. Van Der Kooy K., Van Hout H., Marwijk H., Marten H., Stehouwer C., Beekman A. Depression and the risk for cardiovascular diseases: systematic review and meta analysis. International Journal of Geriatric Psychiatry 2007, 22:613-626.
109. Vogelzangs N., Seldenrijk A., Beekman A.T.F., van Hout H.P.J., de Jonge P., Penninx B.W.J.H. Cardiovascular disease in persons with depressive and anxiety disorders. Journal of Affective Disorders 2010, 125:241-248.
110. Wang H., Yu M., Ochani M., Amella C.A., Tanovic M., Susarla S., Li J.H., Wang H., Yang H., Ulloa L., Al-Abed Y., Czura C.J., Tracey K.J. Nicotinic acetylcholine receptor alpha7 subunit is an essential regulator of inflammation. Nature 2003, 421:384-388.
111. Wells R., Outhred T., Heathers J.A.J., Quintana D.S., Kemp A.H. Matter over mind: a randomised-controlled trial of single-session biofeedback training on performance anxiety and heart rate variability in musicians. PLoS One 2012, 7:e46597.
112. Whang W., Kubzansky L.D., Kawachi I., Rexrode K.M., Kroenke C.H., Glynn R.J., Garan H., Albert C.M. Depression and risk of sudden cardiac death and coronary heart disease in women. Journal of the American College of Cardiology 2009, 53:950-958.
113. Windham B.G., Fumagalli S., Ble A., Sollers J.J., Thayer J.F., Najjar S.S., Griswold M.E., Ferrucci L. The relationship between heart rate variability and adiposity differs for central and overall adiposity. Journal of Obesity 2012, 2012:8.
114. Yasuma F. Respiratory sinus arrhythmia: why does the heartbeat synchronize with respiratory rhythm?. Chest 2004, 125:683-690.
115. Yoo C.S., Lee K., Yi S.H., Kim J.S., Kim H.C. Association of heart rate variability with the Framingham risk score in healthy adults. Korean Journal of Family Medicine 2011, 32:334-340.
116. Zhang Y., Post W.S., Blasco-Colmenares E., Dalal D., Tomaselli G.F., Guallar E. Electrocardiographic QT interval and mortality: a meta-analysis. Epidemiology 2011, 22:660-670.