Heart rate variability and methylphenidate in children with ADHD

ADHD Attention Deficit and Hyperactivity Disorders

Volumn 4, Issue 2, 2012, Pages 85-91

  Buchhorn, Reiner ^a   Conzelmann, Annette ^b   Willaschek, Christian ^a   Störk, Dagmar ^b   Taurines, Regina ^b   Renner, Tobias J ^b  

^a CARITAS KRANKENHAUS   (Germany)

^b UNIVERSITY OF WÜRZBURG   (Germany)

Author keywords

ADHD; Autonomic regulation; Heart rate variability; Methylphenidate; Psychostimulants; Sudden cardiac death; Vagal tone

Indexed keywords

METHYLPHENIDATE;

ARTICLE; ATTENTION DEFICIT DISORDER; AUTONOMIC NERVOUS SYSTEM FUNCTION; CARDIOVASCULAR PARAMETERS; CARDIOVASCULAR RISK; CHILD; CIRCADIAN RHYTHM; CLINICAL ARTICLE; CONTROLLED STUDY; ELECTROCARDIOGRAM; FEMALE; HEART PROTECTION; HEART RATE VARIABILITY; HUMAN; MALE; MATHEMATICAL ANALYSIS; NORMAL SINUS RR STANDARD DEVIATION; OUTPATIENT; PERCENTAGE OF SUCCESSIVE NORMAL SINUS RR INTERVAL GREATER THAN 50 MS; PILOT STUDY; PRIORITY JOURNAL; RISK ASSESSMENT; ROOT MEAN SQUARE OF THE SUCCESSIVE NORMAL SINUS RR INTERVAL DIFFERENCE; RR INTERVAL; SCHOOL CHILD; TIME DOMAIN ANALYSIS; VAGUS TONE;

ATTENTION DEFICIT DISORDER WITH HYPERACTIVITY; CENTRAL NERVOUS SYSTEM STIMULANTS; CHILD; CIRCADIAN RHYTHM; ELECTROCARDIOGRAPHY, AMBULATORY; FEMALE; HEART RATE; HUMANS; MALE; METHYLPHENIDATE;

EID: 84861522836     PISSN: 18666116     EISSN: 18666647     Source Type: Journal    
DOI: 10.1007/s12402-012-0072-8     Document Type: Article

References (29)

1. Al Haddad H, Laursen PB, Ahmaidi S, Buchheit M (2009) Nocturnal heart rate variability following supramaximal intermittent exercise. Int J Sports Physiol Perform 4: 435-447.
2. Arnsten AF (2009) Toward a new understanding of attention-deficit hyperactivity disorder pathophysiology: an important role for prefrontal cortex dysfunction. CNS Drugs 23(Suppl 1): 33-41.
3. Buchhorn R, Hulpke-Wette M, Nothroff J, Paul T (2002) Heart rate variability in infants with heart failure due to congenital heart disease: reversal of depressed heart rate variability by propranolol. Med Sci Monit 8: CR661-6.
4. Cooper WO, Habel LA, Sox CM, Chan KA, Arbogast PG, Cheetham TC, Murray KT, Quinn VP, Stein CM, Callahan ST, Fireman BH, Fish FA, Kirshner HS, O'Duffy A, Connell FA, Ray WA (2011) ADHD drugs and serious cardiovascular events in children and young adults. N Engl J Med 365: 1896-1904.
5. Denchev P, Kaltman JR, Schoenbaum M, Vitiello B (2010) Modeled economic evaluation of alternative strategies to reduce sudden cardiac death among children treated for attention deficit/hyperactivity disorder. Circulation 121: 1329-1337.
6. Faraone SV (2009) Using Meta-analysis to Compare the Efficacy of Medications for Attention-Deficit/Hyperactivity Disorder in Youths. P T 34: 678-694.
7. Fei L, Anderson MH, Katritsis D, Sneddon J, Statters DJ, Malik M, Camm AJ (1994) Decreased heart rate variability in survivors of sudden cardiac death not associated with coronary artery disease. Br Heart J 71: 16-21.
8. Gould MS, Walsh BT, Munfakh JL, Kleinman M, Duan N, Olfson M, Greenhill L, Cooper T (2009) Sudden death and use of stimulant medications in youths. Am J Psychiatry 166: 992-1001.
9. Habel LA, Cooper WO, Sox CM, Chan KA, Fireman BH, Arbogast PG, Cheetham TC, Quinn VP, Dublin S, Boudreau DM, Andrade SE, Pawloski PA, Raebel MA, Smith DH, Achacoso N, Uratsu C, Go AS, Sidney S, Nguyen-Huynh MN, Ray WA, Selby JV (2011) ADHD medications and risk of serious cardiovascular events in young and middle-aged adults. JAMA. 306: 2673-2683.
10. Hammerness P, Wilens T, Mick E, Spencer T, Doyle R, McCreary M, Becker J, Biederman J (2009) Cardiovascular effects of longer-term, high-dose OROS methylphenidate in adolescents with attention deficit hyperactivity disorder. J Pediatr 155: 84-89.
11. Huang YS, Tsai MH (2011) Long-Term Outcomes with Medications for Attention-Deficit Hyperactivity Disorder Current Status of Knowledge. Cns Drugs 25: 539-554.
12. Imeraj L, Antrop I, Roeyers H, Deschepper E, Bal S, Deboutte D (2011) Diurnal variations in arousal: a naturalistic heart rate study in children with ADHD. Eur Child Adolesc Psychiatry 20: 381-392.
13. Jacob CP, Romanos J, Dempfle A, Heine M, Windemuth-Kieselbach C, Kruse A, Reif A, Walitza S, Romanos M, Strobel A, Brocke B, Schäfer H, Schmidtke A, Böning J, Lesch K (2007) Co-morbidity of adult attention-deficit/hyperactivity disorder with focus on personality traits and related disorders in a tertiary referral center. Eur Arch Psychiatry Clin Neurosci 257: 309-317.
14. Leslie LK, Alexander ME, Trikalinos TA, Cohen JT, Parsons SK, Newburger JW (2008) Reexamining the emperor's new clothes: ambiguities in current cardiac screening recommendations for youth with attention deficit hyperactivity disorder. Circ Cardiovasc Qual Outcomes 1: 134-137.
15. McCarthy S, Cranswick N, Potts L, Taylor E, Wong ICK (2009) Mortality associated with attention-deficit hyperactivity disorder (ADHD) drug treatment: a retrospective cohort study of children, adolescents and young adults using the general practice research database. Drug Saf 32: 1089-1096.
16. Negrao BL, Bipath P, van der Westhuizen D, Viljoen M (2011) Autonomic correlates at rest and during evoked attention in children with attention-deficit/hyperactivity disorder and effects of methylphenidate. Neuropsychobiology 63: 82-91.
17. Polanczyk G, Rohde LA (2007) Epidemiology of attention-deficit/hyperactivity disorder across the lifespan. Curr Opin Psychiatry 20: 386-392.
18. Polanczyk G, de Lima MS, Horta BL, Biederman J, Rohde LA (2007) The worldwide prevalence of ADHD: a systematic review and metaregression analysis. Am J Psychiatry 164: 942-948.
19. Polderman TJ, Boomsma DI, Bartels M, Verhulst FC, Huizink AC (2010) A systematic review of prospective studies on attention problems and academic achievement. Acta Psychiatr Scand 122: 271-284.
20. Renner T, Gerlach M, Romanos M, Herrmann M, Reif A, Fallgatter A, Lesch K (2008) Neurobiologie des Aufmerksamkeitsdefizit-/Hyperaktivitätssyndroms. Nervenarzt 79: 771-781.
21. Schelleman H, Bilker WB, Strom BL, Kimmel SE, Newcomb C, Guevara JP, Daniel GW, Cziraky MJ, Hennessy S (2011) Cardiovascular Events and Death in Children Exposed and Unexposed to ADHD Agents. Pediatrics 127: 1102-1110.
22. Schlander M, Trott GE, Schwarz O (2010) The health economics of attention deficit hyperactivity disorder in Germany. Part 1: Health care utilization and cost of illness. Nervenarzt 81: 289-300.
23. Schubert I, Köster I, Lehmkuhl G (2010) The changing prevalence of attention-deficit/hyperactivity disorder and methylphenidate prescriptions: a study of data from a random sample of insurees of the AOK Health Insurance Company in the German State of Hesse, 2000-2007. Dtsch Arztebl Int 107: 615-621.
24. Singh RB, Weydahl A, Otsuka K, Watanabe Y, Yano S, Mori H, Ichimaru Y, Mitsutake G, Sato Y, Fanghong L, Zhao ZY, Kartik C, Gvozdjakova A (2001) Can nutrition influence circadian rhythm and heart rate variability? Biomed Pharmacother 55(Suppl 1): 115s-124s.
25. Singh RB, Kartik C, Otsuka K, Pella D, Pella J (2002) Brain-heart connection and the risk of heart attack. Biomed Pharmacother 56(Suppl 2): 257s-265s.
26. Task Force of the European Society of Cardiology and the North American society of Pacing (1996) Heart rate variability. Standards of measurement, physiological interpretation, and clinical use. Task Force of the European Society of Cardiology and the North American Society of Pacing and Electrophysiology. Eur Heart J 17: 354-381.
27. Taurines R, Schmitt J, Renner T, Conner AC, Warnke A, Romanos M (2010) Developmental comorbidity in attention-deficit/hyperactivity disorder. Atten Defic Hyperact Disord 2: 267-289.
28. Tonhajzerova I, Ondrejka I, Adamik P, Hruby R, Javorka M, Trunkvalterova Z, Mokra D, Javorka K (2009) Changes in the cardiac autonomic regulation in children with attention deficit hyperactivity disorder (ADHD). Indian J Med Res 130: 44-50.
29. Vaseghi M, Shivkumar K (2008) The role of the autonomic nervous system in sudden cardiac death. Prog Cardiovasc Dis 50: 404-419.