-
1
-
-
65249129156
-
Creatine and its potential therapeutic value for targeting cellular energy impairment in neurodegenerative diseases
-
10.1007/s12017-008-8053-y 19005780 10.1007/s12017-008-8053-y 1:CAS:528:DC%2BD1MXhtlKktA%3D%3D
-
Adhihetty P, Beal M (2008) Creatine and its potential therapeutic value for targeting cellular energy impairment in neurodegenerative diseases. Neuromolecular Med 10(4):275-290. doi: 10.1007/s12017-008-8053-y
-
(2008)
Neuromolecular Med
, vol.10
, Issue.4
, pp. 275-290
-
-
Adhihetty, P.1
Beal, M.2
-
2
-
-
83055186656
-
Searching for a therapy of creatine transporter deficiency: Some effects of creatine ethyl ester in brain slices in vitro
-
10.1016/j.neuroscience.2011.09.018 21963865 10.1016/j.neuroscience.2011. 09.018 1:CAS:528:DC%2BC3MXhs1SgsL3M
-
Adriano E, Garbati P, Damonte G, Salis A, Armirotti A, Balestrino M (2011) Searching for a therapy of creatine transporter deficiency: some effects of creatine ethyl ester in brain slices in vitro. Neuroscience 199:386-393. doi: 10.1016/j.neuroscience.2011.09.018
-
(2011)
Neuroscience
, vol.199
, pp. 386-393
-
-
Adriano, E.1
Garbati, P.2
Damonte, G.3
Salis, A.4
Armirotti, A.5
Balestrino, M.6
-
3
-
-
43849087699
-
Functions and effects of creatine in the central nervous system
-
10.1016/j.brainresbull.2008.02.035 18502307 10.1016/j.brainresbull.2008. 02.035 1:CAS:528:DC%2BD1cXmtlWht70%3D
-
Andres RH, Ducray AD, Schlattner U, Wallimann T, Widmer HR (2008) Functions and effects of creatine in the central nervous system. Brain Res Bull 76:329-343. doi: 10.1016/j.brainresbull.2008.02.035
-
(2008)
Brain Res Bull
, vol.76
, pp. 329-343
-
-
Andres, R.H.1
Ducray, A.D.2
Schlattner, U.3
Wallimann, T.4
Widmer, H.R.5
-
4
-
-
0036391841
-
Role of creatine and phosphocreatine in neuronal protection from anoxic and ischemic damage
-
10.1007/s00726-001-0133-3 12373542 10.1007/s00726-001-0133-3 1:CAS:528:DC%2BD38Xns1Gnsbs%3D
-
Balestrino M, Lensman M, Parodi M, Perasso L, Rebaudo R, Melani R, Polenov S, Cupello A (2002) Role of creatine and phosphocreatine in neuronal protection from anoxic and ischemic damage. Amino Acids 23(1-3):221-229. doi: 10.1007/s00726-001-0133-3
-
(2002)
Amino Acids
, vol.23
, Issue.1-3
, pp. 221-229
-
-
Balestrino, M.1
Lensman, M.2
Parodi, M.3
Perasso, L.4
Rebaudo, R.5
Melani, R.6
Polenov, S.7
Cupello, A.8
-
5
-
-
80052809265
-
Neuroprotective effects of creatine
-
doi: 10.1007/s00726-011-0851-0
-
Beal M (2011) Neuroprotective effects of creatine. Amino Acids 1-9. doi: 10.1007/s00726-011-0851-0
-
(2011)
Amino Acids
, pp. 1-9
-
-
Beal, M.1
-
6
-
-
79961172469
-
Creatinyl amino acids - New hybrid compounds with neuroprotective activity
-
10.1002/psc.1379 21644247 10.1002/psc.1379 1:CAS:528:DC%2BC3MXntVWjsLY%3D
-
Burov S, Leko M, Dorosh M, Dobrodumov A, Veselkina O (2011a) Creatinyl amino acids - new hybrid compounds with neuroprotective activity. J Pept Sci 17(9):620-626. doi: 10.1002/psc.1379
-
(2011)
J Pept Sci
, vol.17
, Issue.9
, pp. 620-626
-
-
Burov, S.1
Leko, M.2
Dorosh, M.3
Dobrodumov, A.4
Veselkina, O.5
-
7
-
-
84885289641
-
-
Patent US 2011/0269986 A1 Pub. Date Nov. 3, 2011
-
Burov S, Khromova NV, Khromova AA, Khromov PA (2011b) Patent US 2011/0269986 A1 Amides of creatine, method of their preparation, and remedy possessing a neuroprotective activity, Pub. Date Nov. 3, 2011
-
(2011)
Amides of Creatine, Method of Their Preparation, and Remedy Possessing A Neuroprotective Activity
-
-
Burov, S.1
Khromova, N.V.2
Khromova, A.A.3
Khromov, P.A.4
-
8
-
-
0027441062
-
The 2,2,4,6,7, pentamethyldihydrobenzofuran-5-sulfonyl group (Pbf) as arginine side chain protectant
-
10.1016/S0040-4039(00)61487-9 10.1016/S0040-4039(00)61487-9 1:CAS:528:DyaK2cXislWisbg%3D
-
Carpino LA, Shroff H, Triolo SA, Mansour ESME, Wenschuh H, Albericio F (1993) The 2,2,4,6,7, pentamethyldihydrobenzofuran-5-sulfonyl group (Pbf) as arginine side chain protectant. Tetrahedron Lett 34(49):7829-7832. doi: 10.1016/S0040-4039(00)61487-9
-
(1993)
Tetrahedron Lett
, vol.34
, Issue.49
, pp. 7829-7832
-
-
Carpino, L.A.1
Shroff, H.2
Triolo, S.A.3
Mansour, E.4
Wenschuh, H.5
Albericio, F.6
-
9
-
-
0037525384
-
Using mixed anhydrides from amino acids and isobutyl chloroformate in N-acylations: A case study on the elucidation of mechanism of urethane formation and starting amino acid liberation using carbon dioxide as the probe
-
10.1016/S0040-4039(03)01329-7 10.1016/S0040-4039(03)01329-7 1:CAS:528:DC%2BD3sXkvVGrsLY%3D
-
Chaudhary A, Girgis M, Prashad M, Hu B, Har D, Repič O, Blacklock TJ (2003) Using mixed anhydrides from amino acids and isobutyl chloroformate in N-acylations: a case study on the elucidation of mechanism of urethane formation and starting amino acid liberation using carbon dioxide as the probe. Tetrahedron Lett 44(29):5543-5546. doi: 10.1016/S0040-4039(03)01329-7
-
(2003)
Tetrahedron Lett
, vol.44
, Issue.29
, pp. 5543-5546
-
-
Chaudhary, A.1
Girgis, M.2
Prashad, M.3
Hu, B.4
Har, D.5
Repič, O.6
Blacklock, T.J.7
-
10
-
-
0035854314
-
Solution synthesis and characterization of aza-beta(3)-peptides (N(alpha)-substituted hydrazino acetic acid oligomers)
-
11442427 10.1021/jo001500d 1:CAS:528:DC%2BD3MXksVSjur4%3D
-
Cheguillaume A, Salaün A, Sinbandhit S, Potel M, Gall P, Baudy-Floćh M, Le Grel P (2001) Solution synthesis and characterization of aza-beta(3)-peptides (N(alpha)-substituted hydrazino acetic acid oligomers). J Org Chem 66(14):4923-4929
-
(2001)
J Org Chem
, vol.66
, Issue.14
, pp. 4923-4929
-
-
Cheguillaume, A.1
Salaün, A.2
Sinbandhit, S.3
Potel, M.4
Gall, P.5
Baudy-Floćh, M.6
Le Grel, P.7
-
11
-
-
0032784879
-
A facile method for the transformation of N-(tert-butoxycarbonyl)α- amino acids to N-unprotected α-amino acids methyl esters
-
10.1021/jo990311w 10.1021/jo990311w 1:CAS:528:DyaK1MXnsFCqsb4%3D
-
Chen BC, Skoumbourdis AP, Guo P, Bednarz MS, Kocy OR, Sundeen JE, Vite GD (1999) A facile method for the transformation of N-(tert-butoxycarbonyl) α-amino acids to N-unprotected α-amino acids methyl esters. J Org Chem 64:9294-9296. doi: 10.1021/jo990311w
-
(1999)
J Org Chem
, vol.64
, pp. 9294-9296
-
-
Chen, B.C.1
Skoumbourdis, A.P.2
Guo, P.3
Bednarz, M.S.4
Kocy, O.R.5
Sundeen, J.E.6
Vite, G.D.7
-
12
-
-
0037205815
-
A simple LC method with UV detection for the analysis of creatine and creatinine and its application to several creatine formulations
-
10.1016/S0731-7085(02)00167-X 12093528 10.1016/S0731-7085(02)00167-X 1:CAS:528:DC%2BD38XkvFyrur8%3D
-
Dash AK, Sawhney A (2002) A simple LC method with UV detection for the analysis of creatine and creatinine and its application to several creatine formulations. J Pharm Biomed Anal 29(5):939-945. doi: 10.1016/S0731-7085(02) 00167-X
-
(2002)
J Pharm Biomed Anal
, vol.29
, Issue.5
, pp. 939-945
-
-
Dash, A.K.1
Sawhney, A.2
-
13
-
-
33947490630
-
The equilibrium between creatine and creatinine in aqueous solution. The effect of the hydrogen ion
-
10.1021/ja01681a040 1:CAS:528:DyaB2MXhtFOqsw%3D%3D
-
Edgar G, Shiver HE (1925) The equilibrium between creatine and creatinine in aqueous solution. The effect of the hydrogen ion. J Am Chem Soc 47(4):1179-1188
-
(1925)
J Am Chem Soc
, vol.47
, Issue.4
, pp. 1179-1188
-
-
Edgar, G.1
Shiver, H.E.2
-
14
-
-
0035893870
-
The creatine-phosphocreatine system: There's more than one song in its repertoire
-
10.1113/jphysiol.2001.013478 10.1113/jphysiol.2001.013478 1:CAS:528:DC%2BD38XntVGmsA%3D%3D
-
Greenhaff PL (2001) The creatine-phosphocreatine system: there's more than one song in its repertoire. J Physiol (Lond) 537(3):657. doi: 10.1113/jphysiol.2001.013478
-
(2001)
J Physiol (Lond)
, vol.537
, Issue.3
, pp. 657
-
-
Greenhaff, P.L.1
-
16
-
-
67649274217
-
Amino acid-protecting groups
-
10.1021/cr800323s 19364121 10.1021/cr800323s 1:CAS:528: DC%2BD1MXksVSlur4%3D
-
Isidro-Llobet A, Alvarez M, Albericio F (2009) Amino acid-protecting groups. Chem Rev 109:2455-2504. doi: 10.1021/cr800323s
-
(2009)
Chem Rev
, vol.109
, pp. 2455-2504
-
-
Isidro-Llobet, A.1
Alvarez, M.2
Albericio, F.3
-
17
-
-
44449160328
-
A convenient synthesis of amino acid methyl esters
-
10.3390/molecules13051111 18560331 10.3390/molecules13051111 1:CAS:528:DC%2BD1cXmvVSlsrY%3D
-
Li J, Sha Y (2008) A convenient synthesis of amino acid methyl esters. Molecules 13(5):1111-1119. doi: 10.3390/molecules13051111
-
(2008)
Molecules
, vol.13
, Issue.5
, pp. 1111-1119
-
-
Li, J.1
Sha, Y.2
-
18
-
-
33750297109
-
The creatine transporter mediates the uptake of creatine by brain tissue, but not the uptake of two creatine-derived compounds
-
10.1016/j.neuroscience.2006.06.058 16949212 10.1016/j.neuroscience.2006. 06.058 1:CAS:528:DC%2BD28XhtFCjsbzP
-
Lunardi G, Parodi A, Perasso L, Pohvozcheva AV, Scarrone S, Adriano E, Florio T, Gandolfo C, Cupello A, Burov SV, Balestrino M (2006) The creatine transporter mediates the uptake of creatine by brain tissue, but not the uptake of two creatine-derived compounds. Neuroscience 142(4):991-997. doi: 10.1016/j.neuroscience.2006.06.058
-
(2006)
Neuroscience
, vol.142
, Issue.4
, pp. 991-997
-
-
Lunardi, G.1
Parodi, A.2
Perasso, L.3
Pohvozcheva, A.V.4
Scarrone, S.5
Adriano, E.6
Florio, T.7
Gandolfo, C.8
Cupello, A.9
Burov, S.V.10
Balestrino, M.11
-
19
-
-
76249097469
-
Creatine and Creatine Deficiency Syndromes: Biochemical and clinical aspects
-
10.1016/j.pediatrneurol.2009.07.015 20159424 10.1016/j.pediatrneurol. 2009.07.015
-
Nasrallah F, Feki M, Kaabachi N (2010) Creatine and Creatine Deficiency Syndromes: biochemical and clinical aspects. Pediatr Neurol 42(3):163-171. doi: 10.1016/j.pediatrneurol.2009.07.015
-
(2010)
Pediatr Neurol
, vol.42
, Issue.3
, pp. 163-171
-
-
Nasrallah, F.1
Feki, M.2
Kaabachi, N.3
-
20
-
-
77955586617
-
-
Patent 5,973,199, Date of patent: Oct. 26, 1999
-
Negrisoli G, Del Corona L (1999) Hydrosoluble organic salts of creatine, Patent 5,973,199, Date of patent: Oct. 26, 1999
-
(1999)
Hydrosoluble Organic Salts of Creatine
-
-
Negrisoli, G.1
Del Corona, L.2
-
21
-
-
0031906453
-
Acetyl chloride-methanol as a convenient reagent for: A) quantitative formation of amine hydrochlorides; B) carboxylate ester formation; C) mild removal of N-t-Boc-protective group
-
10.1080/00397919808005101 10.1080/00397919808005101 1:CAS:528: DyaK1cXhsVCrs7o%3D
-
Nudelman A, Bechor Y, Falb E, Fischer B, Wexler BA, Nudelman A (1998) Acetyl chloride-methanol as a convenient reagent for: A) quantitative formation of amine hydrochlorides; B) carboxylate ester formation; C) mild removal of N-t-Boc-protective group. Synth Commun 28(3):471-474. doi: 10.1080/ 00397919808005101
-
(1998)
Synth Commun
, vol.28
, Issue.3
, pp. 471-474
-
-
Nudelman, A.1
Bechor, Y.2
Falb, E.3
Fischer, B.4
Wexler, B.A.5
Nudelman, A.6
-
22
-
-
0036843535
-
The blood-brain barrier creatine transporter is a major pathway for supplying creatine to the brain
-
12439290 10.1097/00004647-200211000-00006 1:CAS:528:DC%2BD38Xosl2gtrc%3D
-
Ohtsuki S, Tachikawa M, Takanaga T, Shimizu H, Watanabe TM, Hosoya K, Terasaki T (2002) The blood-brain barrier creatine transporter is a major pathway for supplying creatine to the brain. J Cereb Blood Flow Metab 22(11):1327-1335
-
(2002)
J Cereb Blood Flow Metab
, vol.22
, Issue.11
, pp. 1327-1335
-
-
Ohtsuki, S.1
Tachikawa, M.2
Takanaga, T.3
Shimizu, H.4
Watanabe, T.M.5
Hosoya, K.6
Terasaki, T.7
-
23
-
-
0038665436
-
Kinetics of creatine in blood and brain after intraperitoneal injection in the rat
-
10.1016/S0006-8993(03)02547-2 12742622 10.1016/S0006-8993(03)02547-2 1:CAS:528:DC%2BD3sXjs1Cktrg%3D
-
Perasso L, Cupello A, Lunardi GL, Principato C, Gandolfo C, Balestrino M (2003) Kinetics of creatine in blood and brain after intraperitoneal injection in the rat. Brain Res 974(1-2):37-42. doi: 10.1016/S0006-8993(03)02547-2
-
(2003)
Brain Res
, vol.974
, Issue.1-2
, pp. 37-42
-
-
Perasso, L.1
Cupello, A.2
Lunardi, G.L.3
Principato, C.4
Gandolfo, C.5
Balestrino, M.6
-
24
-
-
41049102922
-
Protective effects of some creatine derivatives in brain tissue anoxia
-
10.1007/s11064-007-9492-9 17940889 10.1007/s11064-007-9492-9 1:CAS:528:DC%2BD1cXjsFGit7c%3D
-
Perasso L, Lunardi G, Risso F, Pohvozcheva A, Leko M, Gandolfo C, Florio T, Cupello A, Burov S, Balestrino M (2008) Protective effects of some creatine derivatives in brain tissue anoxia. Neurochem Res 33(5):765-775. doi: 10.1007/s11064-007-9492-9
-
(2008)
Neurochem Res
, vol.33
, Issue.5
, pp. 765-775
-
-
Perasso, L.1
Lunardi, G.2
Risso, F.3
Pohvozcheva, A.4
Leko, M.5
Gandolfo, C.6
Florio, T.7
Cupello, A.8
Burov, S.9
Balestrino, M.10
-
25
-
-
84873987487
-
Therapeutic use of creatine in brain or heart ischemia: Available data and future perspectives
-
10.1002/med.20255 22135003 10.1002/med.20255 1:CAS:528: DC%2BC3sXivFartLc%3D
-
Perasso L, Spallarossa P, Gandolfo C, Ruggeri P, Balestrino M (2013) Therapeutic use of creatine in brain or heart ischemia: available data and future perspectives. Med Res Rev 33(2):336-363. doi: 10.1002/med.20255
-
(2013)
Med Res Rev
, vol.33
, Issue.2
, pp. 336-363
-
-
Perasso, L.1
Spallarossa, P.2
Gandolfo, C.3
Ruggeri, P.4
Balestrino, M.5
-
27
-
-
49649113197
-
Creatine - Its chemical synthesis, chemistry, and legal status
-
G.S. Salomons M. Wyss (eds) Springer Berlin
-
Pischel I, Gastner T (2008) Creatine - its chemical synthesis, chemistry, and legal status. In: Salomons GS, Wyss M (eds) Creatine and creatine kinase in health and disease subcellular biochemistry. Springer, Berlin, pp 291-307
-
(2008)
Creatine and Creatine Kinase in Health and Disease Subcellular Biochemistry
, pp. 291-307
-
-
Pischel, I.1
Gastner, T.2
-
28
-
-
84885294354
-
-
Patent 5,863,939, Date of patent Jan. 26, 1999
-
Pischel I, Weiss S, Gloxhuber C, Mertschenk B (1999) Creatine ascorbates and method of producing them, Patent 5,863,939, Date of patent Jan. 26, 1999
-
(1999)
Creatine Ascorbates and Method of Producing Them
-
-
Pischel, I.1
Weiss, S.2
Gloxhuber, C.3
Mertschenk, B.4
-
29
-
-
0037459670
-
Phase-transfer-catalyzed alkylation of guanidines by alkyl halides under biphasic conditions: A convenient protocol for the synthesis of highly functionalized guanidines
-
10.1021/jo0265535 12636395 10.1021/jo0265535 1:CAS:528: DC%2BD3sXht1Sgtbc%3D
-
Powell DA, Ramsden PD, Batey RA (2003) Phase-transfer-catalyzed alkylation of guanidines by alkyl halides under biphasic conditions: a convenient protocol for the synthesis of highly functionalized guanidines. J Org Chem 68(6):2300-2309. doi: 10.1021/jo0265535
-
(2003)
J Org Chem
, vol.68
, Issue.6
, pp. 2300-2309
-
-
Powell, D.A.1
Ramsden, P.D.2
Batey, R.A.3
-
30
-
-
0030948518
-
Solid phase of guanidines
-
10.1016/S0040-4020(97)00225-1 10.1016/S0040-4020(97)00225-1 1:CAS:528:DyaK2sXjtlKhu74%3D
-
Robinson S, Roskamp EJ (1997) Solid phase of guanidines. Tetrahedron 53(19):6697-6705. doi: 10.1016/S0040-4020(97)00225-1
-
(1997)
Tetrahedron
, vol.53
, Issue.19
, pp. 6697-6705
-
-
Robinson, S.1
Roskamp, E.J.2
-
32
-
-
0037306564
-
Creatine deficiency syndromes
-
10.1023/A:1022443503883 12701824 10.1023/A:1022443503883 1:CAS:528:DC%2BD3sXht12jtrk%3D
-
Schulze A (2003) Creatine deficiency syndromes. Mol Cell Biochem 244(1-2):143-150. doi: 10.1023/A:1022443503883
-
(2003)
Mol Cell Biochem
, vol.244
, Issue.1-2
, pp. 143-150
-
-
Schulze, A.1
-
33
-
-
84885292270
-
Creatine Monohydrate
-
H.G. Brittain (eds) 1 34 Elsevier Oxford
-
Singh S, Dash AK (2009) Creatine Monohydrate. In: Brittain HG (ed) Profiles of drug substances, excipients, and related methodology, vol 34, 1st edn. Elsevier, Oxford, pp 18-19
-
(2009)
Profiles of Drug Substances, Excipients, and Related Methodology
, pp. 18-19
-
-
Singh, S.1
Dash, A.K.2
-
34
-
-
0037027845
-
Separation methods applicable to urinary creatine and creatinine
-
10.1016/S1570-0232(02)00617-7 12450655 1:CAS:528:DC%2BD3sXktFCjtA%3D%3D
-
Smith-Palmer T (2002) Separation methods applicable to urinary creatine and creatinine. J Chromatogr B Analyt Technol Biomed Life Sci 781(1-2):93-106. doi: 10.1016/S1570-0232(02)00617-7
-
(2002)
J Chromatogr B Analyt Technol Biomed Life Sci
, vol.781
, Issue.1-2
, pp. 93-106
-
-
Smith-Palmer, T.1
-
35
-
-
0034787869
-
Creatine and the creatine transporter: A review
-
10.1023/A:1011908606819 11693194 10.1023/A:1011908606819 1:CAS:528:DC%2BD3MXot1Ciu78%3D
-
Snow RJ, Murphy RM (2001) Creatine and the creatine transporter: a review. Mol Cell Biochem 224(1-2):169-181. doi: 10.1023/A:1011908606819
-
(2001)
Mol Cell Biochem
, vol.224
, Issue.1-2
, pp. 169-181
-
-
Snow, R.J.1
Murphy, R.M.2
-
36
-
-
79952186878
-
Synthesis and biological activity of amino acid conjugates of abscisic acid
-
10.1016/j.bmc.2011.01.019 21310619 10.1016/j.bmc.2011.01.019 1:CAS:528:DC%2BC3MXisFyltLw%3D
-
Todoroki Y, Narita K, Muramatsu T, Shimomura H, Ohnishi T, Mizutani M, Ueno K, Hirai N (2011) Synthesis and biological activity of amino acid conjugates of abscisic acid. Bioorg Med Chem 19:1743-1750. doi: 10.1016/j.bmc.2011.01.019
-
(2011)
Bioorg Med Chem
, vol.19
, pp. 1743-1750
-
-
Todoroki, Y.1
Narita, K.2
Muramatsu, T.3
Shimomura, H.4
Ohnishi, T.5
Mizutani, M.6
Ueno, K.7
Hirai, N.8
-
37
-
-
0003414262
-
-
9 Merck NJ
-
Windholz M, Budavari S, Stroumtsos Y, Fertig MN (1976) The Merck index: an encyclopedia of chemicals, drugs, and biologicals, 9th edn. Merck, NJ
-
(1976)
The Merck Index: An Encyclopedia of Chemicals, Drugs, and Biologicals
-
-
Windholz, M.1
Budavari, S.2
Stroumtsos, Y.3
Fertig, M.N.4
-
38
-
-
0034597978
-
Aqueous trifluoroacetic acid - An efficient reagent for exclusively cleaving the 5′-end of 3′,5′-TIPDS protected ribonucleosides
-
10.1016/S0040-4039(00)01685-3 1:CAS:528:DC%2BD3cXovFOmsL4%3D
-
Zhu XF, Williams HJ, Scott AI (2000) Aqueous trifluoroacetic acid - an efficient reagent for exclusively cleaving the 5′-end of 3′,5′-TIPDS protected ribonucleosides. Tetrahedron Lett 41(49):9541-9545
-
(2000)
Tetrahedron Lett
, vol.41
, Issue.49
, pp. 9541-9545
-
-
Zhu, X.F.1
Williams, H.J.2
Scott, A.I.3
|