Characterisation of glycoproteins using a quadrupole time-of-flight mass spectrometer configured for electron transfer dissociation

Rapid Communications in Mass Spectrometry

Volumn 27, Issue 21, 2013, Pages 2383-2390

  Williams, Jonathan P ^a   Pringle, Steven ^a   Richardson, Keith ^a   Gethings, Lee ^a   Vissers, Johannes P C ^a   De Cecco, Martin ^a   Houel, Stephane ^a   Chakraborty, Asish B ^a   Yu, Ying Qing ^a   Chen, Weibin ^a   Brown, Jeffery M ^a  

^a WATERS CORPORATION   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

DISSOCIATION; ELECTRON TRANSITIONS; ELECTROSPRAY IONIZATION; GLOW DISCHARGES; IONS; LIQUID CHROMATOGRAPHY; MASS SPECTROMETERS; MASS SPECTROMETRY; PEPTIDES;

DISSOCIATION REACTIONS; ELECTRON TRANSFER DISSOCIATION; GLYCOPEPTIDES; N-LINKED; O-LINKED; QUADRUPOLE-TIME-OF-FLIGHT MASS SPECTROMETER; QUADRUPOLE/TIME OF FLIGHTS; TIME-OF-FLIGHT SYSTEM; TRASTUZUMAB; TRYPTIC PEPTIDES;

GLYCOPROTEINS;

GLYCOPEPTIDE; GLYCOPROTEIN; MONOCLONAL ANTIBODY; TRASTUZUMAB;

AMINO ACID SEQUENCE; ARTICLE; CHEMISTRY; ELECTRON; ELECTROSPRAY MASS SPECTROMETRY; EQUIPMENT; EQUIPMENT DESIGN; LIQUID CHROMATOGRAPHY; METHODOLOGY; MOLECULAR GENETICS;

AMINO ACID SEQUENCE; ANTIBODIES, MONOCLONAL, HUMANIZED; CHROMATOGRAPHY, LIQUID; ELECTRONS; EQUIPMENT DESIGN; GLYCOPEPTIDES; GLYCOPROTEINS; MOLECULAR SEQUENCE DATA; SPECTROMETRY, MASS, ELECTROSPRAY IONIZATION;

EID: 84885220943     PISSN: 09514198     EISSN: 10970231     Source Type: Journal    
DOI: 10.1002/rcm.6684     Document Type: Article

References (40)

1. E. Song, S. Pyreddy, Y. Mechref,. Quantification of glycopeptides by multiple reaction monitoring liquid chromatography/tandem mass spectrometry. Rapid Commun. Mass Spectrom. 2012, 26, 194.
2. http://www.antibodysociety.org/news/approved-mabs.php (2013).
3. K. P. Garnock-Jones, G. M. Keating, L. J. Scott,. Trastuzumab: A review of its use as adjuvant treatment in human epidermal growth factor receptor 2 (HER2)-positive early breast cancer. Drugs 2010, 70, 215.
4. A. Beck, S. Sanglier-Cianférani, A. Van Dorsselaer,. Biosimilar, Biobetter, and next generation antibody characterization by mass spectrometry. Anal. Chem. 2012, 84, 4637.
5. A. Beck, E. Wagner-Rousset, D. Ayoub, A. Van Dorsselaer, S. Sanglier-Cianférani,. Characterization of therapeutic antibodies and related products. Anal. Chem. 2013, 85, 715.
6. R. Jefferis,. Glycosylation of recombinant antibody therapeutics. Biotechnol. Prog. 2005, 21, 11.
7. http://www.fda.gov/downloads/Drugs/ GuidanceComplianceRegulatoryInformation/Guidances/ucm073488.pdf (1999).
8. L. R. Ruhaak, G. Zauner, C. Huhn, C. Bruggink, A. M. Deelder, M. Wuhrer,. Glycan labeling strategies and their use in identification and quantification. Anal. Bioanal. Chem. 2010, 397, 3457.
9. J. E. P Syka, J. J. Coon, M. J. Schroeder, J. Shabanowitz, D. F. Hunt,. Peptide and protein sequence analysis by electron transfer dissociation mass spectrometry. Proc. Natl. Acad. Sci. USA 2004, 101, 9528.
10. J. J. Coon, J. E. P. Syka, J. C. Schwartz, J. Shabanowitz, D. F. Hunt,. Anion dependence in the partitioning between proton and electron transfer in ion/ion reactions. Int. J. Mass Spectrom. 2004, 236, 33.
11. D. L. Swaney, G. C. McAlister, M. Wirtala, J. C. Schwartz, J. E. P. Syka, J. J. Coon,. Supplemental activation method for high-efficiency electron-transfer dissociation of doubly protonated peptide precursors. Anal. Chem. 2007, 79, 477.
12. D. M. Good, M. Wirtala, G. C. McAlister, J. J. Coon,. Performance characteristics of electron transfer dissociation mass spectrometry. Mol. Cell. Proteomics 2007, 6, 1942.
13. S. J. Pitteri, P. A. Chrisman, S. A. McLuckey,. Electron-transfer ion/ion reactions of doubly protonated peptides: Effect of elevated bath gas temperature. Anal. Chem. 2005, 77, 5662.
14. -. Anal. Chem. 2005, 77, 1831.
15. F. Kjeldsen, A. M. B. Giessing, C. R. Ingrell, O. N. Jensen,. Peptide sequencing and characterization of post-translational modifications by enhanced ion-charging and liquid chromatography electron-transfer dissociation tandem mass spectrometry. Anal. Chem. 2007, 79, 9243.
16. Z. Zhu, D. Hua, D. F. Clark, E. P. Go, H. Desaire,. GlycoPep detector: A tool for assigning mass spectrometry data of N-linked glycopeptides on the basis of their electron transfer dissociation spectra. Anal. Chem. 2013, 85, 5023.
17. J. M. Brown, I. Campuzano, S. Pringle, R. Chapman,. Electron transfer dissociation within a rf travelling wave ion guide collision cell of a QTOF. Proc. 56th ASMS Conf. Mass Spectrometry and Allied Topics, Denver, 2008.
18. J. P. Williams, J. M. Brown, I. Campuzano, P. J. Sadler,. Identifying drug metallation sites on peptides using electron transfer dissociation (ETD), collision induced dissociation (CID) and ion mobility-mass spectrometry (IM-MS). Chem. Commun. 2010, 46, 5458.
19. F. A. White,. Mass Spectrometry in Science and Technology. John Wiley. 1968. p. 352.
20. S. A. McLuckey, G. L. Glish, K. G. Asano, B. C. Grant,. Atmospheric sampling glow discharge ionization source for the determination of trace organic compounds in ambient air. Anal. Chem. 1988, 60, 2220.
21. H.P. Gunawardena, M. He, P. A. Chrisman, S. J. Pitteri, J. M. Hogan, B. D. Hodges, S. A. McLuckey,. J. Am. Chem. Soc. 2005, 127, 12627.
22. http://avogadro.openmolecules.net/wiki/Main-Page.
23. M. J. Frisch, G. W. Trucks, H. B. Schlegel, G. E. Scuseria, M. A. Robb, J. R. Cheeseman, G. Scalmani, V. Barone, B. Mennucci, G. A. Petersson, H. Nakatsuji, M. Caricato, X. Li, H. P. Hratchian, A. F. Izmaylov, J. Bloino, G. Zheng, J. L. Sonnenberg, M. Hada, M. Ehara, K. Toyota, R. Fukuda, J. Hasegawa, M. Ishida, T. Nakajima, Y. Honda, O. Kitao, H. Nakai, T. Vreven, J. A. Jr. Montgomery, J. E. Peralta, F. Ogliaro, M. Bearpark, J. J. Heyd, E. Brothers, K. N. Kudin, V. N. Staroverov, R. Kobayashi, J. Normand, K. Raghavachari, A. Rendell, J. C. Burant, S. S. Iyengar, J. Tomasi, M. Cossi, N. Rega, J. M. Millam, M. Klene, J. E. Knox, J. B. Cross, V. Bakken, C. Adamo, J. Jaramillo, R. Gomperts, R. E. Stratmann, O. Yazyev, A. J. Austin, R. Cammi, C. Pomelli, J. W. Ochterski, R. L. Martin, K. Morokuma, V. G. Zakrzewski, G. A. Voth, P. Salvador, J. J. Dannenberg, S. Dapprich, A. D. Daniels, O. Farkas, J. B. Foresman, J. V. Ortiz, J. Cioslowski, D. J. Fox,. Gaussian 09, Revision A.02. Gaussian, Inc., Wallingford, CT, 2009.
24. http://iopenshell.usc.edu/.
25. J. P. Williams, J. Brown, K. Richardson, I. Campuzano, R. Denny, B. Dyson, J. Langridge,. Design of small molecule electron transfer dissociation reagents suitable for Q-TOF based instrumentation. Proc. 59th ASMS Conf. Mass Spectrometry and Allied Topics, Denver, 2011.
26. C. W. N. Damen, W. Chen, A. B. Chakraborty, M. van Oosterhout, J. R. Mazzeo, J. C. Gebler, J. H. M. Schellens, H. Rosing, J. H. Beijnena,. Electrospray ionization quadrupole ion-mobility time-of-flight mass spectrometry as a tool to distinguish the lot-to-lot heterogeneity in N-glycosylation profile of the therapeutic monoclonal antibody trastuzumab. J. Am. Soc. Mass Spectrom. 2009, 20, 2021.
27. J. M. Hogan, S. J. Pitteri, P. A. Chrisman, S. A. McLuckey,. Complementary structural information from a tryptic N-linked glycopeptide via electron transfer ion/ion reactions and collision-induced dissociation. J. Protein Res. 2005, 4, 628.
28. L. M. Mikesh, B. Ueberheide, A. Chi, J. J. Coon, J. E. P. Syka, J. Shabanowitz, D. F. Hunt,. The utility of ETD mass spectrometry in proteomic analysis. Biochim. Biophys. Acta 2006, 1764, 1811.
29. M. Wuhrer, M. I. Catalina, A. M. Deelder, C. H. Hokke,. Glycoproteomics based on tandem mass spectrometry of glycopeptides. J. Chromatogr. B 2007, 849, 115.
30. Z. Darula, K. F. Medzihradszky,. Affinity enrichment and characterization of mucin core-1 type glycopeptides from bovine serum. Mol. Cell. Proteomics 2009, 8, 2515.
31. W. R. Alley, Y. Mechref, M. V. Novotny,. Characterization of glycopeptides by combining collision-induced dissociation and electron-transfer dissociation mass spectrometry data. Rapid Commun. Mass Spectrom. 2009, 23, 161.
32. N. E. Scott, B. L. Parker, A. M. Connolly, J. Paulech, A. V. G. Edwards, B. Crossett, L. Falconer, D. Kolarich, S. P. Djordjevic, P. Højrup, N. H. Packer, M. R. Larsen, S. J. Cordwell,. Simultaneous glycan-peptide characterization using hydrophilic interaction chromatography and parallel fragmentation by CID, higher energy collisional dissociation, and electron transfer dissociation MS applied to the N-linked glycoproteome of Campylobacter jejuni. Mol. Cell. Proteomics 2011, 10, 2515
33. J. Saba, S. Dutta, E. Hemenway, R. Viner,. Increasing the productivity of glycopeptides analysis by using higher-energy collision dissociation-accurate mass-product-dependent electron transfer dissociation. Int. J. Proteomics 2012, DOI: 10.1155/2012/560391.
34. Z. Lin, A. Lo, D. M. Simeone, M T. Ruffin, D. M. Lubman,. An N-glycosylation analysis of human alpha-2-macroglobulin using an integrated approach. J. Prot. Bioinform. 2012, 5, 127.
35. S. A. Myers, S. Daou, E. B. Affar, A. L. Burlingame,. Electron transfer dissociation (ETD): The mass spectrometric breakthrough essential for O-GlcNAc protein site assignments-A study of the O-GlcNAcylated protein host cell factor C1. Proteomics 2013. DOI: 10.1002/pmic.201200332.
36. R. H. Bateman, R. Carruthers, J. B. Hoyes, C. Jones, J. I. Langridge, A. Millar, J. P. Vissers,. A novel precursor ion discovery method on a hybrid quadrupole orthogonal acceleration time-of-flight (Q-TOF) mass spectrometer for studying protein phosphorylation. J. Am. Soc. Mass Spectrom. 2002, 7, 792.
37. S. J. Geromanos, J. P. Vissers, J. C. Silva, C. A. Dorschel, G. Z. Li, M. V. Gorenstein, R. H. Bateman, J. I. Langridge,. The detection, correlation, and comparison of peptide precursor and product ions from data independent LC-MS with data dependant LC-MS/MS. Proteomics 2009, 6, 1683.
38. Y. O. Tsybin, L. Fornelli, C. Stoermer, M. Luebeck, J. Parra, S. Nallet, F. M. Wurm, R. Hartmer,. Structural analysis of intact monoclonal antibodies by electron transfer dissociation mass spectrometry. Anal. Chem. 2011, 83, 8919.
39. L. Fornelli, E. Damoc, P. M. Thomas, N. L. Kelleher, K. Aizikov, E. Denisov, A. Makaraov, Y. O. Tsybin,. Analysis of intact monoclonal antibody IgG1 by electron transfer dissociation Orbitrap FTMS. Mol. Cell. Proteomics 2012, 11, 1758.
40. C. Singh, C. G. Zampronio, A. J. Creese, H. J. Cooper,. Higher energy collision dissociation (HCD) product ion-triggered electron transfer dissociation (ETD) mass spectrometry for the analysis of N-linked glycoproteins. J. Proteome Res. 2012, 11, 1.