Quantitative determination of arenobufagin in rat plasma by ultra fast liquid chromatography-tandem mass spectrometry and its application in a pharmacokinetic study

Journal of Chromatography B: Analytical Technologies in the Biomedical and Life Sciences

Volumn 939, Issue , 2013, Pages 86-91

  Li, Guoliang ^a   Han, Weili ^a   Jiang, Wei ^a   Zhang, Dongmei ^b   Ye, Wencai ^b   Chen, Xiaojia ^c   Ma, Ande ^a  

^a SOUTHERN MEDICAL UNIVERSITY   (China)

^b JINAN UNIVERSITY   (China)

^c University of Macau   (Macao)

Author keywords

Arenobufagin; Intraperitoneal administration; Pharmacokinetics; Rat plasma; UFLC ESI MS MS

Indexed keywords

BODY FLUIDS; ELECTROSPRAY IONIZATION; MASS SPECTROMETRY; PHARMACOKINETICS; PRECIPITATION (CHEMICAL); RATS;

ARENOBUFAGIN; INTRAPERITONEAL ADMINISTRATION; LOWER LIMIT OF QUANTIFICATIONS; MULTIPLE-REACTION MONITORING MODES; QUANTITATIVE DETERMINATIONS; RAT PLASMA; UFLC-ESI-MS/MS; ULTRA-FAST LIQUID CHROMATOGRAPHY;

LIQUID CHROMATOGRAPHY;

ACETONITRILE; ARENOBUFAGIN; CHINESE DRUG; METHANOL; UNCLASSIFIED DRUG; VENOM; WATER;

ACCURACY; ANIMAL EXPERIMENT; AREA UNDER THE CURVE; ARTICLE; BLOOD ANALYSIS; BLOOD LEVEL; CONTROLLED STUDY; DRUG BLOOD LEVEL; DRUG ISOLATION; ELECTROSPRAY; ELUTION; FLOW RATE; LIMIT OF QUANTITATION; MALE; MASS SPECTROMETER; MAXIMUM PLASMA CONCENTRATION; NONHUMAN; PLASMA CONCENTRATION-TIME CURVE; PRECIPITATION; PRIORITY JOURNAL; QUALITY CONTROL; QUANTITATIVE ANALYSIS; RAT; SINGLE DRUG DOSE; SWITCHING VALVE; TANDEM MASS SPECTROMETRY; TIME TO MAXIMUM PLASMA CONCENTRATION; ULTRA PERFORMANCE LIQUID CHROMATOGRAPHY;

RATTUS;

ARENOBUFAGIN; INTRAPERITONEAL ADMINISTRATION; PHARMACOKINETICS; RAT PLASMA; UFLC-ESI-MS/MS;

ANIMALS; BUFANOLIDES; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; DRUG STABILITY; HUMANS; LEAST-SQUARES ANALYSIS; MALE; RATS; RATS, SPRAGUE-DAWLEY; REPRODUCIBILITY OF RESULTS; SENSITIVITY AND SPECIFICITY; TANDEM MASS SPECTROMETRY;

EID: 84885214148     PISSN: 15700232     EISSN: 1873376X     Source Type: Journal    
DOI: 10.1016/j.jchromb.2013.09.019     Document Type: Article

References (20)

1. Xingping L., Zongde Z., Yanfang Z., Liren C., Yongmin L. Anal. Bioanal. Chem. 2006, 384:1254.
2. Chen K.K., Kovarikova A. J. Pharm. Sci. 1967, 56:1535.
3. Krenn L., Kopp B. Phytochemistry 1998, 48:1.
4. Steyn P.S., van Heerden F.R. Nat. Prod. Rep. 1998, 15:397.
5. Cruz J.S., Matsuda H. Eur. J. Pharmacol. 1993, 239:223.
6. Cruz J.S., Matsuda H. Eur. J. Pharmacol. 1994, 266:317.
7. Cao H.H., Zhang D.M., Liu J.S., Hou C.Y., Kurihara H., Ye W.C. Chin. Pharmacol. Bull. 2011, 27:19.
8. Li M., Wu S., Liu Z., Zhang W., Xu J., Wang Y., Liu J., Zhang D., Tian H., Li Y., Ye W. Biochem. Pharmacol. 2012, 83:1251.
9. Wang Z., Wen J., Zhang J., Ye M., Guo D. Biomed. Chromatogr. 2004, 18:318.
10. Zhang L., Bai X., Qi G., Chen X.Y., Hu W.L. Chin. J. Pharm. Anal. 2004, 24:523.
11. Zhang L., Qi G., Zhang L., Gao Y., Ke Z., Xiong X. Chin. Tradit. Herb. Drugs 2007, 38:199.
12. Yang Y., Feng J., Lu J., Luo J. Chin. Tradit. Pat. Med. 2006, 28:787.
13. Liang Y., Liu A.H., Qin S., Sun J.H., Yang M., Li P., Guo D.A. J. Pharm. Biomed. Anal. 2008, 46:442.
14. Oda M., Kurosawa M., Numazawa S., Tanaka S., Akizawa T., Ito K., Maeda M., Yoshida T. Life Sci. 2001, 68:1107.
15. Aoki K., Aoki M., Hirai Y., Kuroiwa Y. Chem. Pharm. Bull. (Tokyo) 1986, 34:1184.
16. Shimizu Y., Morishita S. Am. J. Chin. Med. 1996, 24:289.
17. Zhang Y., Tang X., Liu X., Li F., Lin X. Anal. Chim. Acta 2008, 610:224.
18. Xu W., Luo H., Zhang Y., Shan L., Li H., Yang M., Liu R., Zhang W. J. Chromatogr. 2007, 859:157.
19. Bonfiglio R., King R.C., Olah T.V., Merkle K. Rapid Commun. Mass Spectrom. 1999, 13:1175.
20. USFDA 2001, http://www.fda.gov/cder/guidance/4252fnl.htm.