Characterization of a colorectal cancer migration and autophagy-related microRNA miR-338-5p and its target gene PIK3C3

Biomarkers and Genomic Medicine

Volumn 5, Issue 3, 2013, Pages 74-78

  Ju, Jian An ^a,b   Huang, Ching Tang ^a   Lan, Sheng Hui ^a   Wang, Ting Huei ^c   Lin, Peng Chan ^a   Lee, Jheng Chang ^d   Tian, Yu Feng ^b,e   Liu, Hsiao Sheng ^a,f  

^a NATIONAL CHENG KUNG UNIVERSITY   (Taiwan)

^b CHI MEI MEDICAL CENTER   (Taiwan)

^c INDUSTRIAL TECHNOLOGY RESEARCH INSTITUTE   (Taiwan)

^d NATIONAL CHENG KUNG UNIVERSITY HOSPITAL   (Taiwan)

^e CHIA NAN UNIVERSITY OF PHARMACY AND SCIENCE   (Taiwan)

^f NATIONAL CHENG KUNG UNIVERSITY   (Taiwan)

Author keywords

Autophagy; Colorectal cancer; MicroRNA; Migration; Phosphatidylinositol 3 kinase catalytic subunit type 3

Indexed keywords

MESSENGER RNA; MICRORNA; MICRORNA 338 5P; PHOSPHATIDYLINOSITOL 3 KINASE; PHOSPHATIDYLINOSITOL 3 KINASE CATALYTIC SUBUNIT TYPE 3; RAPAMYCIN; UNCLASSIFIED DRUG;

ARTICLE; AUTOPHAGY; CANCER PATIENT; CELL MIGRATION; CELL PROLIFERATION; CELL STRAIN HCT116; COLORECTAL CANCER; GENE EXPRESSION; GENE TARGETING; HUMAN; HUMAN CELL; METASTASIS; MICROARRAY ANALYSIS; PRIORITY JOURNAL; PROTEIN EXPRESSION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; UPREGULATION;

EID: 84885211981     PISSN: 22140247     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bgm.2013.07.006     Document Type: Article

References (21)

1. Tsai H.L., Cheng K.I., Lu C.Y., et al. Prognostic significance of depth of invasion, vascular invasion and numbers of lymph node retrievals in combination for patients with stage II colorectal cancer undergoing radical resection. J Surg Oncol 2008, 97:383-387.
2. Jérôme T., Laurie P., Louis B., et al. Enjoy the silence: the story of let-7 microRNA and cancer. Curr Genomics 2007, 8:229-233.
3. Hwang H.W., Mendell J.T. MicroRNAs in cell proliferation, cell death, and tumorigenesis. Br J Cancer 2006, 94:776-780.
4. Johnson S.M., Grosshans H., Shingara J., et al. RAS is regulated by the let-7 microRNA family. Cell 2005, 120:635-647.
5. Lu Z., Liu M., Stribinskis V., et al. MicroRNA-21 promotes cell transformation by targeting the programmed cell death 4 gene. Oncogene 2008, 27:4373-4379.
6. Barik S. An intronic microRNA silences genes that are functionally antagonistic to its host gene. Nucleic Acids Res 2008, 36:5232-5241.
7. Huang X.H., Wang Q., Chen J.S., et al. Bead-based microarray analysis of microRNA expression in hepatocellular carcinoma: miR-338 is downregulated. Hepatol Res 2009, 39:786-794.
8. Ju J.A., Huang Y.C., Lan S.H., et al. Identification of colorectal cancer recurrence-related microRNAs. Genomic Med Biomarkers Health Sci 2012, 4:19-20.
9. Yong F.L., Law C.W., Wang C.W. Potentiality of a triple microRNA classifier: miR-193a-3p, miR-23a and miR-338-5p for early detection of colorectal cancer. BMC Cancer 2013, 13:280.
10. Ng G., Huang J. The significance of autophagy in cancer. Mol Carcinog 2005, 43:183-187.
11. Hippert M.M., O'Toole P.S., Thorburn A. Autophagy in cancer: good, bad, or both?. Cancer Res 2006, 66:9349-9351.
12. Kondo Y., Kanzawa T., Sawaya R., et al. The role of autophagy in cancer development and response to therapy. Nat Rev Cancer 2005, 5:726-734.
13. Itakura E., Kishi C., Inoue K., et al. Beclin 1 forms two distinct phosphatidylinositol 3-kinase complexes with mammalian Atg14 and UVRAG. Mol Biol Cell 2008, 19:5360-5372.
14. Sun Y., Liu J.H., Sui Y.X., et al. Beclin1 overexpression inhibitis proliferation, invasion and migration of CaSki cervical cancer cells. Asian Pac J Cancer Prev 2011, 12:1269-1273.
15. Deryugina E.I., Quigley J.P. Matrix metalloproteinases and tumor metastasis. Cancer Metastasis Rev 2006, 25:9-34.
16. Schetter A.J., Leung S.Y., Sohn J.J., et al. MicroRNA expression profiles associated with prognosis and therapeutic outcome in colon adenocarcinoma. JAMA 2008, 299:425-436.
17. Budhu A., Jia H.L., Forgues M., et al. Identification of metastasis-related microRNAs in hepatocellular carcinoma. Hepatology 2008, 47:897-907.
18. Wong T.S., Liu X.B., Wong B.Y., et al. Mature miR-184 as potential oncogenic microRNA of squamous cell carcinoma of tongue. Clin Cancer Res 2008, 14:2588-2592.
19. Kim J., Guan K.L. AMPK connects energy stress to PIK3C3/VPS34 regulation. Autophagy 2013, 9:1110-1111.
20. Cho D.H., Jo Y.K., Kim S.C., et al. Down-regulated expression of ATG5 in colorectal cancer. Anticancer Res 2012, 32:4091-4096.
21. Lv Q., Wang W., Xue J., et al. DEDD interacts with PI3KC3 to activate autophagy and attenuate epithelial-mesenchymal transition in human breast cancer. Cancer Res 2012, 72:3238-3250.