2′-hydroxy C16-ceramide induces apoptosis-associated proteomic changes in C6 glioma cells

Journal of Proteome Research

Volumn 12, Issue 10, 2013, Pages 4366-4375

  Kota, Venkatesh ^a   Dhople, Vishnu M ^b   Fullbright, George ^a   Smythe, Nancy M ^a   Szulc, Zdzislaw M ^a   Bielawska, Alicja ^a   Hama, Hiroko ^a  

^a MEDICAL UNIVERSITY OF SOUTH CAROLINA   (United States)

^b UNIVERSITY OF GREIFSWALD   (Germany)

Author keywords

Akt phosphorylation; ceramide; gel proteomics; MAPK pathway

Indexed keywords

2' HYDROXY C16 CERAMIDE; CASPASE 3; CERAMIDE DERIVATIVE; GLYCOGEN SYNTHASE KINASE 3BETA; LIPOCORTIN 5; MITOGEN ACTIVATED PROTEIN KINASE; MITOGEN ACTIVATED PROTEIN KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE 3; MITOGEN ACTIVATED PROTEIN KINASE P38; PROTEIN KINASE B; STRESS ACTIVATED PROTEIN KINASE; UNCLASSIFIED DRUG; 2'-HYDROXY C16-CERAMIDE; ANTINEOPLASTIC AGENT; CERAMIDE; PROTEOME;

ANIMAL CELL; APOPTOSIS; ARTICLE; CHROMATIN CONDENSATION; COMPUTER PROGRAM; CONTROLLED STUDY; ENZYME KINETICS; GEL ELECTROPHORESIS; GLIOMA CELL; NONHUMAN; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN CLEAVAGE; PROTEIN DEPHOSPHORYLATION; PROTEIN INTERACTION; PROTEIN PHOSPHORYLATION; PROTEOMICS; RAT; SIGNAL TRANSDUCTION; STEREOISOMERISM; ANIMAL; CELL PROLIFERATION; DRUG EFFECTS; GLIOMA; HUMAN; METABOLISM; PHOSPHORYLATION; PROTEIN PROCESSING; TUMOR CELL LINE; DRUG EFFECT;

ANIMALS; ANTINEOPLASTIC AGENTS; APOPTOSIS; CELL LINE, TUMOR; CELL PROLIFERATION; CERAMIDES; GLIOMA; HUMANS; MAP KINASE SIGNALING SYSTEM; MITOGEN-ACTIVATED PROTEIN KINASES; PHOSPHORYLATION; PROTEIN PROCESSING, POST-TRANSLATIONAL; PROTEOME; PROTO-ONCOGENE PROTEINS C-AKT; RATS;

EID: 84885202063     PISSN: 15353893     EISSN: 15353907     Source Type: Journal    
DOI: 10.1021/pr4003432     Document Type: Article

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