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Volumn 20, Issue 10, 2013, Pages 1074-1083

Blockade of substance P receptor attenuates osteoporotic pain, but not bone loss, in ovariectomized mice

Author keywords

Hyperalgesia; NK1 receptor; Osteoporosis; Ovariectomy; Substance P

Indexed keywords

2 BENZHYDRYL 3 (2 IODOBENZYLAMINO)QUINUCLIDINE; SUBSTANCE P ANTAGONIST;

EID: 84885178131     PISSN: 10723714     EISSN: 15300374     Source Type: Journal    
DOI: 10.1097/GME.0b013e31828837a6     Document Type: Article
Times cited : (16)

References (63)
  • 1
    • 0027104212 scopus 로고
    • Determination of the amino acid residues in substance P conferring selectivity and specificity for the rat neurokinin receptors
    • Cascieri MA, Huang RR, Fong TM, et al. Determination of the amino acid residues in substance P conferring selectivity and specificity for the rat neurokinin receptors. Mol Pharmacol 1992;41: 1096-1099.
    • (1992) Mol Pharmacol , vol.41 , pp. 1096-1099
    • Cascieri, M.A.1    Huang, R.R.2    Fong, T.M.3
  • 2
    • 78650490994 scopus 로고    scopus 로고
    • Changes in tissue substance P levels in patients with carpal tunnel syndrome
    • ö ztürk N, Erin N, Tüzüner S. Changes in tissue substance P levels in patients with carpal tunnel syndrome. Neurosurgery 2010;67: 1655-1661.
    • (2010) Neurosurgery , vol.67 , pp. 1655-1661
    • Öztürk, N.1    Erin, N.2    Tüzüner, S.3
  • 3
    • 0037192420 scopus 로고    scopus 로고
    • Local neurokinin-1 receptor in the knee joint contributes to the induction, but not maintenance, of arthritic pain in the rat
    • Hong SK, Han JS, Min SS, et al. Local neurokinin-1 receptor in the knee joint contributes to the induction, but not maintenance, of arthritic pain in the rat. Neurosci Lett 2002;322: 21-24.
    • (2002) Neurosci Lett , vol.322 , pp. 21-24
    • Hong, S.K.1    Han, J.S.2    Min, S.S.3
  • 4
    • 69649089496 scopus 로고    scopus 로고
    • Role of substance P signaling in enhanced nociceptive sensitization and local cytokine production after incision
    • Sahbaie P, Shi X, Guo TZ, et al. Role of substance P signaling in enhanced nociceptive sensitization and local cytokine production after incision. Pain 2009;145: 341-349.
    • (2009) Pain , vol.145 , pp. 341-349
    • Sahbaie, P.1    Shi, X.2    Guo, T.Z.3
  • 5
    • 34548689372 scopus 로고    scopus 로고
    • Continuous intra-arterial application of substance P induces signs and symptoms of experimental complex regional pain syndrome (CRPS) such as edema, inflammation and mechanical pain but no thermal pain
    • Gradl G, Finke B, Schattner S, Gierer P, Mittlmeier T, Vollmar B. Continuous intra-arterial application of substance P induces signs and symptoms of experimental complex regional pain syndrome (CRPS) such as edema, inflammation and mechanical pain but no thermal pain. Neuroscience 2007;148: 757-765.
    • (2007) Neuroscience , vol.148 , pp. 757-765
    • Gradl, G.1    Finke, B.2    Schattner, S.3    Gierer, P.4    Mittlmeier, T.5    Vollmar, B.6
  • 6
    • 67649470432 scopus 로고    scopus 로고
    • Post-junctional facilitation of substance P signaling in a tibia fracture rat model of complex regional pain syndrome type I
    • Wei T, Li WW, Guo TZ, et al. Post-junctional facilitation of substance P signaling in a tibia fracture rat model of complex regional pain syndrome type I. Pain 2009;144: 278-286.
    • (2009) Pain , vol.144 , pp. 278-286
    • Wei, T.1    Li, W.W.2    Guo, T.Z.3
  • 7
    • 79952116085 scopus 로고    scopus 로고
    • Role of neuropeptide, cytokine, and growth factor signaling in complex regional pain syndrome
    • Kingery WS. Role of neuropeptide, cytokine, and growth factor signaling in complex regional pain syndrome. Pain Med 2010;11: 1239-1250.
    • (2010) Pain Med , vol.11 , pp. 1239-1250
    • Kingery, W.S.1
  • 8
    • 0038500684 scopus 로고    scopus 로고
    • A substance P receptor (NK1) antagonist can reverse vascular and nociceptive abnormalities in a rat model of complex regional pain syndrome type II
    • Kingery WS, Davies MF, Clark JD. A substance P receptor (NK1) antagonist can reverse vascular and nociceptive abnormalities in a rat model of complex regional pain syndrome type II. Pain 2003;104: 75-84.
    • (2003) Pain , vol.104 , pp. 75-84
    • Kingery, W.S.1    Davies, M.F.2    Clark, J.D.3
  • 9
    • 34447282998 scopus 로고    scopus 로고
    • Involvement of substance P and calcitonin geneYrelated peptide in development and maintenance of neuropathic pain from spinal nerve injury model of rat
    • Lee SE, Kim JH. Involvement of substance P and calcitonin geneYrelated peptide in development and maintenance of neuropathic pain from spinal nerve injury model of rat. Neurosci Res 2007;58: 245-249.
    • (2007) Neurosci Res , vol.58 , pp. 245-249
    • Lee, S.E.1    Kim, J.H.2
  • 10
    • 77953486186 scopus 로고    scopus 로고
    • Estrogen effects on pain sensitivity and neuropeptide expression in rat sensory neurons
    • Sarajari S, Oblinger MM. Estrogen effects on pain sensitivity and neuropeptide expression in rat sensory neurons. Exp Neurol 2010;224: 163-169.
    • (2010) Exp Neurol , vol.224 , pp. 163-169
    • Sarajari, S.1    Oblinger, M.M.2
  • 11
    • 47249124483 scopus 로고    scopus 로고
    • Changes of substance PYimmunoreactive nerve fiber innervation density in the sublesional bones in young growing rats at an early stage after spinal cord injury
    • Liu D, Li H, Zhao CQ, Jiang LS, Dai LY. Changes of substance PYimmunoreactive nerve fiber innervation density in the sublesional bones in young growing rats at an early stage after spinal cord injury. Osteoporos Int 2008;19: 559-569.
    • (2008) Osteoporos Int , vol.19 , pp. 559-569
    • Liu, D.1    Li, H.2    Zhao, C.Q.3    Jiang, L.S.4    Dai, L.Y.5
  • 12
    • 0347356609 scopus 로고    scopus 로고
    • Bone loss induced by dietary magnesium reduction to 10% of the nutrient requirement in rats is associated with increased release of substance P and tumor necrosis factor->
    • Rude RK, Gruber HE, Norton HJ, Wei LY, Frausto A, Mills BG. Bone loss induced by dietary magnesium reduction to 10% of the nutrient requirement in rats is associated with increased release of substance P and tumor necrosis factor->. J Nutr 2004;134: 79-85.
    • (2004) J Nutr , vol.134 , pp. 79-85
    • Rude, R.K.1    Gruber, H.E.2    Norton, H.J.3    Wei, L.Y.4    Frausto, A.5    Mills, B.G.6
  • 13
    • 0346996347 scopus 로고    scopus 로고
    • A substance P receptor (NK1) antagonist enhances the widespread osteoporotic effects of sciatic nerve section
    • Kingery WS, Offley SC, Guo TZ, Davies MF, Clark JD, Jacobs CR. A substance P receptor (NK1) antagonist enhances the widespread osteoporotic effects of sciatic nerve section. Bone 2003;33: 927-936.
    • (2003) Bone , vol.33 , pp. 927-936
    • Kingery, W.S.1    Offley, S.C.2    Guo, T.Z.3    Davies, M.F.4    Clark, J.D.5    Jacobs, C.R.6
  • 14
    • 0036851758 scopus 로고    scopus 로고
    • The influence of back pain on balance and functional mobility in 65- to 75-year-old women with osteoporosis
    • Liu-Ambrose T, Eng JJ, Khan KM, Mallinson A, Carter ND, McKay HA. The influence of back pain on balance and functional mobility in 65- to 75-year-old women with osteoporosis. Osteoporos Int 2002;13: 868-873.
    • (2002) Osteoporos Int , vol.13 , pp. 868-873
    • Liu-Ambrose, T.1    Eng, J.J.2    Khan, K.M.3    Mallinson, A.4    Carter, N.D.5    McKay, H.A.6
  • 15
    • 42949131193 scopus 로고    scopus 로고
    • Estrogen modulation of ovariectomy-induced hyperalgesia in adult mice
    • Sanoja R, Cervero F. Estrogen modulation of ovariectomy-induced hyperalgesia in adult mice. Eur J Pain 2008;12: 573-581.
    • (2008) Eur J Pain , vol.12 , pp. 573-581
    • Sanoja, R.1    Cervero, F.2
  • 16
    • 27644573431 scopus 로고    scopus 로고
    • Estrogen-dependent abdominal hyperalgesia induced by ovariectomy in adult mice: A model of functional abdominal pain
    • Sanoja R, Cervero F. Estrogen-dependent abdominal hyperalgesia induced by ovariectomy in adult mice: a model of functional abdominal pain. Pain 2005;118: 243-253.
    • (2005) Pain , vol.118 , pp. 243-253
    • Sanoja, R.1    Cervero, F.2
  • 17
    • 67349163785 scopus 로고    scopus 로고
    • Modulatory role of estradiol in nicotinic antinociception in adult female rats
    • Chen Y, Cui Y, Lin JW, Xiang QL, Liu WF, Wang TH. Modulatory role of estradiol in nicotinic antinociception in adult female rats. Life Sci 2009;85: 91-96.
    • (2009) Life Sci , vol.85 , pp. 91-96
    • Chen, Y.1    Cui, Y.2    Lin, J.W.3    Xiang, Q.L.4    Liu, W.F.5    Wang, T.H.6
  • 18
    • 35348862345 scopus 로고    scopus 로고
    • Estrogen receptor A is essential for sprouting of nociceptive primary afferents and for morphogenesis and maintenance of the dorsal horn interneurons
    • Fan X, Kim HJ, Warner M, Gustafsson JA. Estrogen receptor A is essential for sprouting of nociceptive primary afferents and for morphogenesis and maintenance of the dorsal horn interneurons. Proc Natl Acad Sci 2007;104: 13696-13701.
    • (2007) Proc Natl Acad Sci , vol.104 , pp. 13696-13701
    • Fan, X.1    Kim, H.J.2    Warner, M.3    Gustafsson, J.A.4
  • 19
    • 0042706195 scopus 로고    scopus 로고
    • Substance P in the uterine cervix, dorsal root ganglia and spinal cord during pregnancy and the effect of estrogen on SP synthesis
    • Mowa C. Substance P in the uterine cervix, dorsal root ganglia and spinal cord during pregnancy and the effect of estrogen on SP synthesis. Peptides 2003;24: 761-771.
    • (2003) Peptides , vol.24 , pp. 761-771
    • Mowa, C.1
  • 20
    • 54949105805 scopus 로고    scopus 로고
    • Effects of estrogen on age-related changes in muscarinic responsiveness of the urinary bladder and lumbosacral dorsal root ganglion cells in female rats
    • Watanabe T, Matsumoto M, Toji S, Miyagawa I. Effects of estrogen on age-related changes in muscarinic responsiveness of the urinary bladder and lumbosacral dorsal root ganglion cells in female rats. Mol Cell Biochem 2008;318: 53-61.
    • (2008) Mol Cell Biochem , vol.318 , pp. 53-61
    • Watanabe, T.1    Matsumoto, M.2    Toji, S.3    Miyagawa, I.4
  • 21
    • 33645818157 scopus 로고    scopus 로고
    • Spinal estrogen attenuates the exercise pressor reflex but has little effect on the expression of genes regulating neurotransmitters in the dorsal root ganglia
    • Schmitt PM, Gohil K, Kaufman MP. Spinal estrogen attenuates the exercise pressor reflex but has little effect on the expression of genes regulating neurotransmitters in the dorsal root ganglia. J Appl Physiol 2006; 100: 958-964.
    • (2006) J Appl Physiol , vol.100 , pp. 958-964
    • Schmitt, P.M.1    Gohil, K.2    Kaufman, M.P.3
  • 22
    • 73449111540 scopus 로고    scopus 로고
    • Risedronate decreases bone resorption and improves low back pain in postmenopausal osteoporosis patients without vertebral fractures
    • Ohtori S, Akazawa T, Murata Y, et al. Risedronate decreases bone resorption and improves low back pain in postmenopausal osteoporosis patients without vertebral fractures. J Clin Neurosci 2010;17: 209-213.
    • (2010) J Clin Neurosci , vol.17 , pp. 209-213
    • Ohtori, S.1    Akazawa, T.2    Murata, Y.3
  • 23
    • 78650264647 scopus 로고    scopus 로고
    • Use of recombinant human parathyroid hormone(1-84) in patients with postmenopausal osteoporosis: A prospective, open-label, single-arm, multicentre, observational cohort study of the effects of treatment on quality of life and painVthe PROPOSE study
    • Moricke R, Rettig K, Bethke TD. Use of recombinant human parathyroid hormone(1-84) in patients with postmenopausal osteoporosis: a prospective, open-label, single-arm, multicentre, observational cohort study of the effects of treatment on quality of life and painVthe PROPOSE study. Clin Drug Investig 2011;31: 87-99.
    • (2011) Clin Drug Investig , vol.31 , pp. 87-99
    • Moricke, R.1    Rettig, K.2    Bethke, T.D.3
  • 24
    • 6344232104 scopus 로고    scopus 로고
    • Effects of alendronate on metacarpal and lumbar bone mineral density, bone resorption, and chronic back pain in postmenopausal women with osteoporosis
    • Iwamoto J, Takeda T, Sato Y, Uzawa M. Effects of alendronate on metacarpal and lumbar bone mineral density, bone resorption, and chronic back pain in postmenopausal women with osteoporosis. Clin Rheumatol 2004;23: 383-389.
    • (2004) Clin Rheumatol , vol.23 , pp. 383-389
    • Iwamoto, J.1    Takeda, T.2    Sato, Y.3    Uzawa, M.4
  • 25
    • 84863541661 scopus 로고    scopus 로고
    • Elcatonin in combination with risedronate is more effective than risedronate alone for relieving back pain in postmenopausal women with osteoporosis
    • Takakuwa M, Iwamoto J. Elcatonin in combination with risedronate is more effective than risedronate alone for relieving back pain in postmenopausal women with osteoporosis. Biol Pharm Bull 2012;35: 1159-1165.
    • (2012) Biol Pharm Bull , vol.35 , pp. 1159-1165
    • Takakuwa, M.1    Iwamoto, J.2
  • 26
    • 79951868498 scopus 로고    scopus 로고
    • Risk reduction of falls and fractures, reduction of back pain and safety in elderly high risk patients receiving combined therapy with alfacalcidol and alendronate: A prospective study
    • Schacht E, Ringe JD. Risk reduction of falls and fractures, reduction of back pain and safety in elderly high risk patients receiving combined therapy with alfacalcidol and alendronate: a prospective study. Arzneimittelforschung 2011;61: 40-54.
    • (2011) Arzneimittelforschung , vol.61 , pp. 40-54
    • Schacht, E.1    Ringe, J.D.2
  • 27
    • 75149144858 scopus 로고    scopus 로고
    • Substance P stimulates differentiation of mice osteoblast through up-regulating the expression of Osterix
    • Sun HB, Liu Q, Guo MF, Zhang HP, Chen JC. Substance P stimulates differentiation of mice osteoblast through up-regulating the expression of Osterix. J Xi'an Jiaotong Univ 2009;30: 716-719.
    • (2009) J xi'An Jiaotong Univ , vol.30 , pp. 716-719
    • Sun, H.B.1    Liu, Q.2    Guo, M.F.3    Zhang, H.P.4    Chen, J.C.5
  • 28
    • 67649452522 scopus 로고    scopus 로고
    • Substance P stimulates bone marrow stromal cell osteogenic activity, osteoclast differentiation, and resorption activity in vitro
    • Wang L, Zhao R, Shi X, et al. Substance P stimulates bone marrow stromal cell osteogenic activity, osteoclast differentiation, and resorption activity in vitro. Bone 2009;45: 309-320.
    • (2009) Bone , vol.45 , pp. 309-320
    • Wang, L.1    Zhao, R.2    Shi, X.3
  • 29
    • 33846081607 scopus 로고    scopus 로고
    • Substance P stimulates late-stage rat osteoblastic bone formation through neurokinin-1 receptors
    • Goto T, Nakao K, Gunjigake KK, Kido MA, Kobayashi S, Tanaka T. Substance P stimulates late-stage rat osteoblastic bone formation through neurokinin-1 receptors. Neuropeptides 2007;41: 25-31.
    • (2007) Neuropeptides , vol.41 , pp. 25-31
    • Goto, T.1    Nakao, K.2    Gunjigake, K.K.3    Kido, M.A.4    Kobayashi, S.5    Tanaka, T.6
  • 30
    • 0033610070 scopus 로고    scopus 로고
    • Substance P regulates the function of rabbit cultured osteoclast; Increase of intracellular free calcium concentration and enhancement of bone resorption
    • Mori T, Ogata T, Okumura H, Shibata T, Nakamura Y, Kataoka K. Substance P regulates the function of rabbit cultured osteoclast; increase of intracellular free calcium concentration and enhancement of bone resorption. Biochem Biophys Res Commun 1999;262: 418-422.
    • (1999) Biochem Biophys Res Commun , vol.262 , pp. 418-422
    • Mori, T.1    Ogata, T.2    Okumura, H.3    Shibata, T.4    Nakamura, Y.5    Kataoka, K.6
  • 32
    • 34247632616 scopus 로고    scopus 로고
    • Differences of bone mass and bone structure in osteopenic rat models caused by spinal cord injury and ovariectomy
    • Jiang SD, Shen C, Jiang LS, Dai LY. Differences of bone mass and bone structure in osteopenic rat models caused by spinal cord injury and ovariectomy. Osteoporos Int 2007;18: 743-750.
    • (2007) Osteoporos Int , vol.18 , pp. 743-750
    • Jiang, S.D.1    Shen, C.2    Jiang, L.S.3    Dai, L.Y.4
  • 33
    • 80051602755 scopus 로고    scopus 로고
    • Nav1.9 channel contributes to mechanical and heat pain hypersensitivity induced by subacute and chronic inflammation
    • Lolignier S, Amsalem M, Maingret F, et al. Nav1.9 channel contributes to mechanical and heat pain hypersensitivity induced by subacute and chronic inflammation. PLoS One 2011;6:e23083.
    • (2011) PLoS One , vol.6
    • Lolignier, S.1    Amsalem, M.2    Maingret, F.3
  • 34
    • 77649236090 scopus 로고    scopus 로고
    • Neurokinin-1 receptors (NK1R:S), alcohol consumption, and alcohol reward in mice
    • Thorsell A, Schank JR, Singley E, Hunt SP, Heilig M. Neurokinin-1 receptors (NK1R:s), alcohol consumption, and alcohol reward in mice. Psychopharmacology 2010;209: 103-111.
    • (2010) Psychopharmacology , vol.209 , pp. 103-111
    • Thorsell, A.1    Schank, J.R.2    Singley, E.3    Hunt, S.P.4    Heilig, M.5
  • 35
    • 0027092664 scopus 로고
    • Osteoporosis and chronic back pain: A study with single-photon emission computed tomography bone scintigraphy
    • Ryan PJ, Evans P, Gibson T, Fogelman I. Osteoporosis and chronic back pain: a study with single-photon emission computed tomography bone scintigraphy. J Bone Miner Res 1992;7: 1455-1460.
    • (1992) J Bone Miner Res , vol.7 , pp. 1455-1460
    • Ryan, P.J.1    Evans, P.2    Gibson, T.3    Fogelman, I.4
  • 36
    • 20044386353 scopus 로고    scopus 로고
    • AA-Afferents activate neurokinin-1 receptor in dorsal horn neurons after nerve injury
    • Zheng JH, Song XJ. AA-Afferents activate neurokinin-1 receptor in dorsal horn neurons after nerve injury. Neuroreport 2005;16: 715-719.
    • (2005) Neuroreport , vol.16 , pp. 715-719
    • Zheng, J.H.1    Song, X.J.2
  • 37
    • 0033845060 scopus 로고    scopus 로고
    • Different subtypes of tachykinin NK (1) receptor binding sites are present in the rat brain
    • Beaujouan JC, Saffroy M, Torrens Y, Glowinski J. Different subtypes of tachykinin NK(1) receptor binding sites are present in the rat brain. J Neurochem 2000;75: 1015-1026.
    • (2000) J Neurochem , vol.75 , pp. 1015-1026
    • Beaujouan, J.C.1    Saffroy, M.2    Torrens, Y.3    Glowinski, J.4
  • 38
    • 0037177455 scopus 로고    scopus 로고
    • Neurokinin NK1 and NK3- immunoreactive neurons in serotonergic cell groups in the rat brain
    • Leger L, Gay N, Cespuglio R. Neurokinin NK1- and NK3- immunoreactive neurons in serotonergic cell groups in the rat brain. Neurosci Lett 2002;323: 146-150.
    • (2002) Neurosci Lett , vol.323 , pp. 146-150
    • Leger, L.1    Gay, N.2    Cespuglio, R.3
  • 40
    • 44249108287 scopus 로고    scopus 로고
    • Lateral hypothalamic-induced antinociception may be mediated by a substance P connection with the rostral ventromedial medulla
    • Holden JE, Pizzi JA. Lateral hypothalamic-induced antinociception may be mediated by a substance P connection with the rostral ventromedial medulla. Brain Res 2008;1214: 40-49.
    • (2008) Brain Res , vol.1214 , pp. 40-49
    • Holden, J.E.1    Pizzi, J.A.2
  • 41
    • 72749113618 scopus 로고    scopus 로고
    • Effects of neurokinin-1 receptor agonism and antagonism in the rostral ventromedial medulla of rats with acute or persistent inflammatory nociception
    • Hamity MV, White SR, Hammond DL. Effects of neurokinin-1 receptor agonism and antagonism in the rostral ventromedial medulla of rats with acute or persistent inflammatory nociception. Neuroscience (Research Support, NIH, Extramural) 2010;165: 902-913.
    • (2010) Neuroscience (Research Support, NIH, Extramural) , vol.165 , pp. 902-913
    • Hamity, M.V.1    White, S.R.2    Hammond, D.L.3
  • 42
    • 0024361850 scopus 로고
    • The response to analgesia testing is affected by gonadal steroids in the rat
    • Forman LJ, Tingle V, Estilow S, Cater J. The response to analgesia testing is affected by gonadal steroids in the rat. Life Sci 1989;45: 447-454.
    • (1989) Life Sci , vol.45 , pp. 447-454
    • Forman, L.J.1    Tingle, V.2    Estilow, S.3    Cater, J.4
  • 43
    • 0034662505 scopus 로고    scopus 로고
    • Mechanisms for ovariectomy-induced hyperalgesia and its relief by calcitonin: Participation of 5-HT1AYlike receptor on C-afferent terminals in substantia gelatinosa of the rat spinal cord
    • Ito A, Kumamoto E, Takeda M, Shibata K, Sagai H, Yoshimura M. Mechanisms for ovariectomy-induced hyperalgesia and its relief by calcitonin: participation of 5-HT1AYlike receptor on C-afferent terminals in substantia gelatinosa of the rat spinal cord. J Neurosci 2000;20: 6302-6308.
    • (2000) J Neurosci , vol.20 , pp. 6302-6308
    • Ito, A.1    Kumamoto, E.2    Takeda, M.3    Shibata, K.4    Sagai, H.5    Yoshimura, M.6
  • 44
  • 46
    • 0037008424 scopus 로고    scopus 로고
    • Origins of skeletal pain: Sensory and sympathetic innervation of the mouse femur
    • Mach DB, Rogers SD, Sabino MC, et al. Origins of skeletal pain: sensory and sympathetic innervation of the mouse femur. Neuroscience 2002; 113: 155-166.
    • (2002) Neuroscience , vol.113 , pp. 155-166
    • MacH, D.B.1    Rogers, S.D.2    Sabino, M.C.3
  • 47
    • 0032696046 scopus 로고    scopus 로고
    • Evidence for a dense and intimate innervation of the bone tissue, including glutamate-containing fibers
    • Serre CM, Farlay D, Delmas PD, Chenu C. Evidence for a dense and intimate innervation of the bone tissue, including glutamate-containing fibers. Bone 1999;25: 623-629.
    • (1999) Bone , vol.25 , pp. 623-629
    • Serre, C.M.1    Farlay, D.2    Delmas, P.D.3    Chenu, C.4
  • 48
    • 35448929372 scopus 로고    scopus 로고
    • Organization of a unique net-like meshwork of CGRP+ sensory fibers in the mouse periosteum: Implications for the generation and maintenance of bone fracture pain
    • Martin CD, Jimenez-Andrade JM, Ghilardi JR, Mantyh PW. Organization of a unique net-like meshwork of CGRP+ sensory fibers in the mouse periosteum: implications for the generation and maintenance of bone fracture pain. Neurosci Lett 2007;427: 148-152.
    • (2007) Neurosci Lett , vol.427 , pp. 148-152
    • Martin, C.D.1    Jimenez-Andrade, J.M.2    Ghilardi, J.R.3    Mantyh, P.W.4
  • 49
    • 0037098915 scopus 로고    scopus 로고
    • Adrenergic regulation of bone metabolism: Possible involvement of sympathetic innervation of osteoblastic and osteoclastic cells
    • Togari A. Adrenergic regulation of bone metabolism: possible involvement of sympathetic innervation of osteoblastic and osteoclastic cells. Microsc Res Tech 2002;58: 77-84.
    • (2002) Microsc Res Tech , vol.58 , pp. 77-84
    • Togari, A.1
  • 50
    • 0034652131 scopus 로고    scopus 로고
    • Developmental changes in the transmitter properties of sympathetic neurons that innervate the periosteum
    • Asmus SE, Parsons S, Landis SC. Developmental changes in the transmitter properties of sympathetic neurons that innervate the periosteum. J Neurosci 2000;20: 1495-1504.
    • (2000) J Neurosci , vol.20 , pp. 1495-1504
    • Asmus, S.E.1    Parsons, S.2    Landis, S.C.3
  • 51
    • 11144231703 scopus 로고    scopus 로고
    • Dramatic decrease of innervation density in bone after ovariectomy
    • Burt-Pichat B. Dramatic decrease of innervation density in bone after ovariectomy. Endocrinology 2004;146: 503-510.
    • (2004) Endocrinology , vol.146 , pp. 503-510
    • Burt-Pichat, B.1
  • 52
    • 0035057053 scopus 로고    scopus 로고
    • Levels of vasodilators (SP, CGRP) and vasoconstrictor (NPY) peptides in early human burns
    • Onuoha GN, Alpar EK. Levels of vasodilators (SP, CGRP) and vasoconstrictor (NPY) peptides in early human burns. Eur J Clin Investig 2001; 31: 253-257.
    • (2001) Eur J Clin Investig , vol.31 , pp. 253-257
    • Onuoha, G.N.1    Alpar, E.K.2
  • 53
    • 0033855887 scopus 로고    scopus 로고
    • Elevation of plasma CGRP and SP levels in orthopedic patients with fracture neck of femur
    • Onuoha GN, Alpar EK. Elevation of plasma CGRP and SP levels in orthopedic patients with fracture neck of femur. Neuropeptides 2000;34: 116-120.
    • (2000) Neuropeptides , vol.34 , pp. 116-120
    • Onuoha, G.N.1    Alpar, E.K.2
  • 55
    • 63349084176 scopus 로고    scopus 로고
    • Systemic inflammatory mediators in post-traumatic complex regional pain syndrome (CRPS I)Vlongitudinal investigations and differences to control groups
    • Schinkel C, Scherens A, Koller M, Roellecke G, Muhr G, Maier C. Systemic inflammatory mediators in post-traumatic complex regional pain syndrome (CRPS I)Vlongitudinal investigations and differences to control groups. Eur J Med Res 2009;14: 130-135.
    • (2009) Eur J Med Res , vol.14 , pp. 130-135
    • Schinkel, C.1    Scherens, A.2    Koller, M.3    Roellecke, G.4    Muhr, G.5    Maier, C.6
  • 56
    • 33846243742 scopus 로고    scopus 로고
    • Plasma neuropeptides in patients undergoing lumbar discectomy
    • Takeuchi H, Kawaguchi S, Ohwada O, et al. Plasma neuropeptides in patients undergoing lumbar discectomy. Spine 2007;32:E79-E84.
    • (2007) Spine , vol.32
    • Takeuchi, H.1    Kawaguchi, S.2    Ohwada, O.3
  • 57
    • 45549109711 scopus 로고    scopus 로고
    • Local and systemic release of cytokines, nerve growth factor, prostaglandin E2, and substance P in incisional wounds and serum following cesarean delivery
    • Carvalho B, Clark DJ, Angst MS. Local and systemic release of cytokines, nerve growth factor, prostaglandin E2, and substance P in incisional wounds and serum following cesarean delivery. J Pain 2008;9: 650-657.
    • (2008) J Pain , vol.9 , pp. 650-657
    • Carvalho, B.1    Clark, D.J.2    Angst, M.S.3
  • 58
    • 0031037298 scopus 로고    scopus 로고
    • Plasma and saliva substance P levels: The effects of acute pain in pregnant and non-pregnant women
    • Dalby PL, Ramanathan S, Rudy TE, Roy L, Amenta JS, Aber A. Plasma and saliva substance P levels: the effects of acute pain in pregnant and non-pregnant women. Pain 1997;69: 263-267.
    • (1997) Pain , vol.69 , pp. 263-267
    • Dalby, P.L.1    Ramanathan, S.2    Rudy, T.E.3    Roy, L.4    Amenta, J.S.5    Aber, A.6
  • 59
    • 77955304164 scopus 로고    scopus 로고
    • A-995662 [(R)-8-(4-methyl-5-(4- (trifluoromethyl)phenyl)oxazol-2-ylamino) -1, 2, 34-tetrahydr onaphthalen-2- ol] a novel selective TRPV1 receptor antagonist reduces spinal release of glutamate and CGRP in a rat knee joint pain model
    • Puttfarcken PS, Han P, Joshi SK, et al. A-995662 [(R)-8-(4-methyl-5-(4- (trifluoromethyl)phenyl)oxazol-2-ylamino)-1,2,3,4-tetrahydr onaphthalen-2- ol], a novel, selective TRPV1 receptor antagonist, reduces spinal release of glutamate and CGRP in a rat knee joint pain model. Pain 2010;150: 319-326.
    • (2010) Pain , vol.150 , pp. 319-326
    • Puttfarcken, P.S.1    Han, P.2    Joshi, S.K.3
  • 60
    • 0036295872 scopus 로고    scopus 로고
    • A non-peptide substance P antagonist down-regulates SP mRNA expression in human mononuclear phagocytes
    • Lai JP, Ho WZ, Yang JH, Wang X, Song L, Douglas SD. A non-peptide substance P antagonist down-regulates SP mRNA expression in human mononuclear phagocytes. J Neuroimmunol 2002;128: 101-108.
    • (2002) J Neuroimmunol , vol.128 , pp. 101-108
    • Lai, J.P.1    Ho, W.Z.2    Yang, J.H.3    Wang, X.4    Song, L.5    Douglas, S.D.6
  • 61
    • 51249116922 scopus 로고    scopus 로고
    • Presence of substance P and the neurokinin-1 receptor in tenocytes of the human Achilles tendon
    • Andersson G, Danielson P, Alfredson H, Forsgren S. Presence of substance P and the neurokinin-1 receptor in tenocytes of the human Achilles tendon. Regul Pept 2008;150: 81-87.
    • (2008) Regul Pept , vol.150 , pp. 81-87
    • Andersson, G.1    Danielson, P.2    Alfredson, H.3    Forsgren, S.4
  • 62
    • 0037215591 scopus 로고    scopus 로고
    • Airway smooth muscle cells express functional neurokinin-1 receptors and the nerve-derived preprotachykinin- A gene: Regulation by passive sensitization
    • Maghni K, Michoud MC, Alles M, et al. Airway smooth muscle cells express functional neurokinin-1 receptors and the nerve-derived preprotachykinin- A gene: regulation by passive sensitization. Am J Respir Cell Mol Biol 2003;28: 103-110.
    • (2003) Am J Respir Cell Mol Biol , vol.28 , pp. 103-110
    • Maghni, K.1    Michoud, M.C.2    Alles, M.3
  • 63
    • 79551587116 scopus 로고    scopus 로고
    • Evidence for regulatory diversity and auto-regulation at the TAC1 locus in sensory neurones
    • Shanley L, Lear M, Davidson S, Ross R, MacKenzie A. Evidence for regulatory diversity and auto-regulation at the TAC1 locus in sensory neurones. J Neuroinflamm 2011;8: 10.
    • (2011) J Neuroinflamm , vol.8 , pp. 10
    • Shanley, L.1    Lear, M.2    Davidson, S.3    Ross, R.4    MacKenzie, A.5


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