Galactosyltransferase knockout pigs produce the natural anti-Gal antibody and simulate the evolutionary appearance of this antibody in primates

Xenotransplantation

Volumn 20, Issue 5, 2013, Pages 267-276

  Galili, Uri ^a  

^a UNIVERSITY OF MASSACHUSETTS MEDICAL SCHOOL   (United States)

Author keywords

Anti Gal; Gal epitope; Galactosyltransferase; GT KO pigs; Primate evolution

Indexed keywords

ALPHA 1,3 GALACTOSYLTRANSFERASE; ANTIBODY; EPITOPE; GALACTOSYLTRANSFERASE; GALACTOSYLTRANSFERASE ANTIBODY; IMMUNOGLOBULIN; IMMUNOGLOBULIN G; IMMUNOGLOBULIN M; UNCLASSIFIED DRUG; ALPHA-GALACTOSYL EPITOPE; TRISACCHARIDE;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ANTIBODY PRODUCTION; ARTICLE; CYTOLYSIS; ENZYME LINKED IMMUNOSORBENT ASSAY; ERYTHROCYTE; HUMAN; KIDNEY HOMOGENATE; MARSUPIAL; NONHUMAN; PLATYRRHINI; PRIORITY JOURNAL; SWINE; WILD TYPE; ANIMAL; CARBOHYDRATE ANALYSIS; EVOLUTION; GENE INACTIVATION; GENETICS; IMMUNOLOGY; PHYSIOLOGY; PRIMATE; TRANSGENIC ANIMAL; XENOGRAFT;

ANIMALS; ANIMALS, GENETICALLY MODIFIED; ANTIBODIES; BIOLOGICAL EVOLUTION; CARBOHYDRATE SEQUENCE; GALACTOSYLTRANSFERASES; GENE KNOCKOUT TECHNIQUES; HUMANS; IMMUNOGLOBULINS; PRIMATES; SWINE; TRANSPLANTATION, HETEROLOGOUS; TRISACCHARIDES;

EID: 84885176030     PISSN: 0908665X     EISSN: 13993089     Source Type: Journal    
DOI: 10.1111/xen.12051     Document Type: Article

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