Magnesium lithospermate B protects neurons from N-methyl-d-aspartic acid injury and attenuates kainic acid-induced neurodegeration in FVB mice

Journal of Molecular Neuroscience

Volumn 51, Issue 2, 2013, Pages 550-557

  Xiao, Guodong ^a,c   Hu, Weidong ^a   Chen, Xuesong ^b  

^a THE SECOND AFFILIATED HOSPITAL OF SOOCHOW UNIVERSITY   (China)

^b MEDICAL SCHOOL OF NANJING UNIVERSITY   (China)

^c NONE   (China)

Author keywords

Akt phosphorylation; GSK 3 phosphorylation; Magnesium lithospermate B; Neurodegeration; Neuroprotection

Indexed keywords

2 MORPHOLINO 8 PHENYLCHROMONE; GLYCOGEN SYNTHASE KINASE 3BETA; KAINIC ACID; MAGNESIUM LITHOSPERMATE; N METHYL DEXTRO ASPARTIC ACID; PHOSPHATIDYLINOSITOL 3 KINASE; PROTEIN KINASE B; TRICIRIBINE;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; DOSE RESPONSE; DRUG EFFICACY; DRUG MECHANISM; EMBRYO; ENZYME PHOSPHORYLATION; FVB MOUSE; HIPPOCAMPAL NEURONAL CULTURE; MOUSE; NERVE CELL LESION; NERVE CELL NECROSIS; NERVE DEGENERATION; NERVE FIBER GROWTH; NEUROPROTECTION; NONHUMAN; PROTEIN DEPHOSPHORYLATION; SIGNAL TRANSDUCTION; TREATMENT DURATION;

MUS; SALVIA MILTIORRHIZA;

ANIMALS; CELLS, CULTURED; DOSE-RESPONSE RELATIONSHIP, DRUG; DRUGS, CHINESE HERBAL; GLYCOGEN SYNTHASE KINASE 3; HIPPOCAMPUS; KAINIC ACID; MICE; N-METHYLASPARTATE; NEURONS; NEUROPROTECTIVE AGENTS; PHOSPHATIDYLINOSITOL 3-KINASES; PROTEIN KINASE INHIBITORS; PROTO-ONCOGENE PROTEINS C-AKT;

EID: 84885174882     PISSN: 08958696     EISSN: 15591166     Source Type: Journal    
DOI: 10.1007/s12031-013-0023-7     Document Type: Article

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