Structural and mechanistic basis for enhanced translational efficiency by 2-thiouridine at the tRNA anticodon wobble position

Journal of Molecular Biology

Volumn 425, Issue 20, 2013, Pages 3888-3906

  Rodriguez Hernandez, Annia ^a,b   Spears, Jessica L ^c   Gaston, Kirk W ^d   Limbach, Patrick A ^d   Gamper, Howard ^e   Hou, Ya Ming ^e   Kaiser, Rob ^f   Agris, Paul F ^c   Perona, John J ^a,b  

^a PORTLAND STATE UNIVERSITY   (United States)

^b OREGON HEALTH AND SCIENCE UNIVERSITY   (United States)

^c STATE UNIVERSITY OF NEW YORK   (United States)

^d UNIVERSITY OF CINCINNATI   (United States)

^e THOMAS JEFFERSON UNIVERSITY   (United States)

^f Thermo Fisher Scientific   (United States)

Author keywords

glutaminyl tRNA synthetase; peptidyl transfer; pre steady state kinetics; ribosome; transfer RNA

Indexed keywords

ADENOSINE TRIPHOSPHATE; GLUTAMINE TRANSFER RNA LIGASE; SYNTHETIC PEPTIDE; THIOURIDINE; TRANSFER RNA;

AMINOACYLATION; ANTICODON; ARTICLE; BINDING AFFINITY; CAG REPEAT; CONTROLLED STUDY; CRYOPROTECTION; CRYSTAL STRUCTURE; ESCHERICHIA COLI; HYDROLYSIS; IN VIVO STUDY; MASS SPECTROMETRY; PRIORITY JOURNAL; PROTEIN DOMAIN; PROTEIN PROTEIN INTERACTION; PROTEIN RNA BINDING; RIBOSOME; RNA ANALYSIS; RNA STRUCTURE; RNA TRANSCRIPTION; STEADY STATE;

BACTERIA (MICROORGANISMS); ESCHERICHIA COLI; EUKARYOTA;

EID: 84885172817     PISSN: 00222836     EISSN: 10898638     Source Type: Journal    
DOI: 10.1016/j.jmb.2013.05.018     Document Type: Article

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