Dopamine D2 receptor-mediated epidermal growth factor receptor transactivation through a disintegrin and metalloprotease regulates dopaminergic neuron development via extracellular signal-related kinase activation

Journal of Biological Chemistry

Volumn 288, Issue 40, 2013, Pages 28435-28446

  Yoon, Sehyoun ^a   Baik, Ja Hyun ^a  

^a Korea University   (South Korea)

Author keywords

[No Author keywords available]

Indexed keywords

DOPAMINERGIC NEURONS; EPIDERMAL GROWTH FACTOR RECEPTORS; HEPARIN BINDING; KINASE ACTIVATION; METALLO-PROTEASE; METALLOPROTEINASES; NEURONAL DEVELOPMENT; TRANSACTIVATION;

AMINES; CHEMICAL ACTIVATION; ENZYME ACTIVITY;

NEURONS;

ADAM PROTEIN; ADAM10 ENDOPEPTIDASE; ADAM17 PROTEIN; DOPAMINE 2 RECEPTOR; EPIDERMAL GROWTH FACTOR; EPIDERMAL GROWTH FACTOR RECEPTOR; MITOGEN ACTIVATED PROTEIN KINASE; UNCLASSIFIED DRUG;

ANIMAL CELL; ARTICLE; CONTROLLED STUDY; DOPAMINERGIC NERVE CELL; ENZYME ACTIVATION; KNOCKOUT MOUSE; MESENCEPHALON; MOUSE; NERVE CELL DIFFERENTIATION; NERVE FIBER GROWTH; NONHUMAN; PRIORITY JOURNAL; REGULATORY MECHANISM;

ADAM; ADAMTS; DOPAMINE RECEPTORS; DOPAMINERGIC NEURON DEVELOPMENT; EPIDERMAL GROWTH FACTOR RECEPTOR (EGFR); ERK; SIGNAL TRANSDUCTION;

ADAM PROTEINS; AMYLOID PRECURSOR PROTEIN SECRETASES; ANIMALS; CELLS, CULTURED; DOPAMINERGIC NEURONS; ENZYME ACTIVATION; EXTRACELLULAR SIGNAL-REGULATED MAP KINASES; GENE KNOCKDOWN TECHNIQUES; IMMUNOHISTOCHEMISTRY; INTERCELLULAR SIGNALING PEPTIDES AND PROTEINS; MATRIX METALLOPROTEINASE INHIBITORS; MEMBRANE PROTEINS; MESENCEPHALON; MICE; RECEPTOR, EPIDERMAL GROWTH FACTOR; RECEPTORS, DOPAMINE D2; TRANSCRIPTIONAL ACTIVATION; TYROSINE 3-MONOOXYGENASE;

EID: 84885168622     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M113.461202     Document Type: Article

References (29)

1. Lindvall, O., and Kokaia, Z. (2009) Prospects of stem cell therapy for replacing dopamine neurons in Parkinson's disease. Trends Pharmacol. Sci. 30, 260-267
2. Smidt, M. P., and Burbach, J. P. (2007) How to make a mesodiencephalic dopaminergic neuron. Nat. Rev. Neurosci. 8, 21-32
3. Perrone-Capano, C., Da Pozzo, P., and di Porzio, U. (2000) Epigenetic cues in midbrain dopaminergic neuron development. Neurosci. Biobehav. Rev. 24, 119-124
4. Simon, H. H., Bhatt, L., Gherbassi, D., Sgadó, P., and Alberí, L. (2003) Midbrain dopaminergic neurons: determination of their developmental fate by transcription factors. Ann. N.Y. Acad. Sci. 991, 36-47
5. Riddle, R., and Pollock, J. D. (2003) Making connections: the development of mesencephalic dopaminergic neurons. Brain Res. Dev. Brain Res. 147, 3-21
6. Perlmann, T., and Wallén-Mackenzie, A. (2004) Nurr1, an orphan nuclear receptor with essential functions in developing dopamine cells. Cell Tissue Res. 318, 45-52
7. Kim, S. Y., Choi, K. C., Chang, M. S., Kim, M. H., Kim, S. Y., Na, Y. S., Lee, J. E., Jin, B. K., Lee, B. H., and Baik, J. H. (2006) The dopamine D2 receptor regulates the development of dopaminergic neurons via extracellular signal-regulated kinase and Nurr1 activation. J. Neurosci. 26, 4567-4576
8. Kim, S. Y., Lee, H. J., Kim, Y. N., Yoon, S., Lee, J. E., Sun, W., Choi, E. J., and Baik, J. H. (2008) Striatal-enriched protein tyrosine phosphatase regulates dopaminergic neuronal development via extracellular signal-regulated kinase signaling. Exp. Neurol. 214, 69-77
9. Yoon, S., Choi, M. H., Chang, M. S., and Baik, J. H. (2011) Wnt5adopamine D2 receptor interactions regulate dopamine neuron development via extracellular signal-regulated kinase (ERK) activation. J. Biol. Chem. 286, 15641-15651
10. Liebmann, C. (2011) EGF receptor activation by GPCRs: a universal pathway reveals different versions. Mol. Cell. Endocrinol. 331, 222-231
11. Wang, C., Buck, D. C., Yang, R., Macey, T. A., and Neve, K. A. (2005) Dopamine D2 receptor stimulation of mitogen-activated protein kinases mediated by cell type-dependent transactivation of receptor tyrosine kinases. J. Neurochem. 93, 899-909
12. Yan, Y., Shirakabe, K., and Werb, Z. (2002) The metalloprotease Kuzbanian (ADAM10) mediates the transactivation of EGF receptor by G protein-coupled receptors. J. Cell Biol. 158, 221-226
13. Sahin, U., Weskamp, G., Kelly, K., Zhou, H. M., Higashiyama, S., Peschon, J., Hartmann, D., Saftig, P., and Blobel, C. P. (2004) Distinct roles for ADAM10 and ADAM17 in ectodomain shedding of six EGFR ligands. J. Cell Biol. 164, 769-779
14. Higashiyama, S., and Nanba, D. (2005) ADAM-mediated ectodomain shedding of HB-EGF in receptor cross-talk. Biochim. Biophys. Acta 1751, 110-117
15. Ohtsu, H., Dempsey, P. J., and Eguchi, S. (2006) ADAMs as mediators of EGF receptor transactivation by G protein-coupled receptors. Am. J. Physiol. Cell Physiol. 291, C1-10
16. Huovila, A. P., Turner, A. J., Pelto-Huikko, M., Kärkkäinen, I., and Ortiz, R. M. (2005) Shedding light on ADAM metalloproteinases. Trends Biochem. Sci. 30, 413-422
17. Caiazzo, M., Dell'Anno, M. T., Dvoretskova, E., Lazarevic, D., Taverna, S., Leo, D., Sotnikova, T. D., Menegon, A., Roncaglia, P., Colciago, G., Russo, G., Carninci, P., Pezzoli, G., Gainetdinov, R. R., Gustincich, S., Dityatev, A., and Broccoli, V. (2011) Direct generation of functional dopaminergic neurons from mouse and human fibroblasts. Nature 476, 224-227
18. Kim, S. J., Kim, M. Y., Lee, E. J., Ahn, Y. S., and Baik, J. H. (2004) Distinct regulation of internalization and mitogen-activated protein kinase activation by two isoforms of the dopamine D2 receptor. Mol. Endocrinol. 18, 640-652
19. Diaz, J., Ridray, S., Mignon, V., Griffon, N., Schwartz, J. C., Sokoloff, P. (1997) Selective expression of dopamine D2 receptor mRNA in proliferative zones during embryonic development of the rat brain. J. Neurosci. 17, 4282-4292
20. Farkas, L. M., and Krieglstein, K. (2002) Heparin-binding epidermal growth factor-like growth factor (HB-EGF) regulates survival of midbrain dopaminergic neurons. J. Neural Transm. 109, 267-277
21. Oyagi, A., Oida, Y., Kakefuda, K., Shimazawa, M., Shioda, N., Moriguchi, S., Kitaichi, K., Nanba, D., Yamaguchi, K., Furuta, Y., Fukunaga, K., Higashiyama, S., and Hara, H. (2009) Generation and characterization of conditional heparin-binding EGF-like growth factor knockout mice. PLoS One 4, e7461
22. Moses, D., Teper, Y., Gantois, I., Finkelstein, D. I., Horne, M. K., and Drago, J. (2006) Murine embryonic EGF-responsive ventral mesencephalic neurospheres display distinct regional specification and promote survival of dopaminergic neurons. Exp. Neurol. 199, 209-221
23. Inoue, H., Lin, L., Lee, X., Shao, Z., Mendes, S., Snodgrass-Belt, P., Sweigard, H., Engber, T., Pepinsky, B., Yang, L., Beal, M. F., Mi, S., and Isacson, O. (2007) Inhibition of the leucine-rich repeat protein LINGO-1 enhances survival, structure, and function of dopaminergic neurons in Parkinson's disease models. Proc. Natl. Acad. Sci. U.S.A. 104, 14430-14435
24. O'Keeffe, G. C., Tyers, P., Aarsland, D., Dalley, J. W., Barker, R. A., and Caldwell, M. A. (2009) Dopamine-induced proliferation of adult neural precursor cells in the mammalian subventricular zone is mediated through EGF. Proc. Natl. Acad. Sci. U.S.A. 106, 8754-8759
25. Iwakura, Y., Zheng, Y., Sibilia, M., Abe, Y., Piao, Y. S., Yokomaku, D., Wang, R., Ishizuka, Y., Takei, N., and Nawa, H. (2011) Qualitative and quantitative re-evaluation of epidermal growth factor-ErbB1 action on developing midbrain dopaminergic neurons in vivo and in vitro: targetderived neurotrophic signaling (part 1). J. Neurochem. 118, 45-56
26. Iwakura, Y., Wang, R., Abe, Y., Piao, Y. S., Shishido, Y., Higashiyama, S., Takei, N., and Nawa, H. (2011) Dopamine-dependent ectodomain shedding and release of epidermal growth factor in developing striatum: targetderived neurotrophic signaling (part 2). J. Neurochem. 118, 57-68
27. Goldstein, M., and Deutch, A. Y. (1992) Dopaminergic mechanisms in the pathogenesis of schizophrenia. FASEB J. 6, 2413-2421
28. Futamura, T., Toyooka, K., Iritani, S., Niizato, K., Nakamura, R., Tsuchiya, K., Someya, T., Kakita, A., Takahashi, H., and Nawa, H. (2002) Abnormal expression of epidermal growth factor and its receptor in the forebrain and serum of schizophrenic patients. Mol. Psychiatry 7, 673-682
29. Iwakura Y., Piao Y. S., Mizuno M., Takei N., Kakita A., Takahashi H., and Nawa H. (2005) Influence of dopaminergic lesion on epidermal growth factor-ErbB1 signals in Parkinson's disease and its model: neurotrophic implication in nigrostriatal neurons. J. Neurochem. 93, 974-983