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Volumn 8, Issue 10, 2013, Pages

Genetic Characteristics of the Human Hepatic Stellate Cell Line LX-2

Author keywords

[No Author keywords available]

Indexed keywords

ALPHA SMOOTH MUSCLE ACTIN; COLLAGEN TYPE 4; CONNECTIVE TISSUE GROWTH FACTOR; DESMIN; ENDOGLIN; FIBRONECTIN; RECOMBINANT TRANSFORMING GROWTH FACTOR BETA2; TRANSFORMING GROWTH FACTOR BETA1; VIMENTIN; VIRUS T ANTIGEN;

EID: 84885153238     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0075692     Document Type: Article
Times cited : (48)

References (35)
  • 1
    • 35948954244 scopus 로고    scopus 로고
    • Hepatic stellate cells: protean, multifunctional, and enigmatic cells of the liver
    • Friedman SL, (2008) Hepatic stellate cells: protean, multifunctional, and enigmatic cells of the liver. Physiol Rev 88: 125-172.
    • (2008) Physiol Rev , vol.88 , pp. 125-172
    • Friedman, S.L.1
  • 2
    • 83455259787 scopus 로고    scopus 로고
    • Update on hepatic stellate cells: pathogenic role in liver fibrosis and novel isolation techniques
    • Tacke F, Weiskirchen R, (2012) Update on hepatic stellate cells: pathogenic role in liver fibrosis and novel isolation techniques. Expert Rev Gastroenterol Hepatol 6: 67-80.
    • (2012) Expert Rev Gastroenterol Hepatol , vol.6 , pp. 67-80
    • Tacke, F.1    Weiskirchen, R.2
  • 3
    • 34548180280 scopus 로고    scopus 로고
    • Immortal hepatic stellate cell lines: useful tools to study hepatic stellate cell biology and function?
    • Herrmann J, Gressner AM, Weiskirchen R, (2007) Immortal hepatic stellate cell lines: useful tools to study hepatic stellate cell biology and function? J Cell Mol Med 11: 704-722.
    • (2007) J Cell Mol Med , vol.11 , pp. 704-722
    • Herrmann, J.1    Gressner, A.M.2    Weiskirchen, R.3
  • 4
    • 10844242987 scopus 로고    scopus 로고
    • Human hepatic stellate cell lines, LX-1 and LX-2: new tools for analysis of hepatic fibrosis
    • Xu L, Hui AY, Albanis E, Arthur MJ, O'Byrne SM, et al. (2005) Human hepatic stellate cell lines, LX-1 and LX-2: new tools for analysis of hepatic fibrosis. GUT 54: 142-151.
    • (2005) GUT , vol.54 , pp. 142-151
    • Xu, L.1    Hui, A.Y.2    Albanis, E.3    Arthur, M.J.4    O'Byrne, S.M.5
  • 5
    • 0034808310 scopus 로고    scopus 로고
    • History, heterogeneity, developmental biology, and functions of quiescent hepatic stellate cells
    • Geerts A, (2001) History, heterogeneity, developmental biology, and functions of quiescent hepatic stellate cells. Semin Liver Dis 21: 311-335.
    • (2001) Semin Liver Dis , vol.21 , pp. 311-335
    • Geerts, A.1
  • 6
    • 0037219276 scopus 로고    scopus 로고
    • Activated stellate cells express the TRAIL receptor-2/death receptor-5 and undergo TRAIL-mediated apoptosis
    • Taimr P, Higuchi H, Kocova E, Rippe RA, Friedman S, et al. (2003) Activated stellate cells express the TRAIL receptor-2/death receptor-5 and undergo TRAIL-mediated apoptosis. Hepatology 37: 87-95.
    • (2003) Hepatology , vol.37 , pp. 87-95
    • Taimr, P.1    Higuchi, H.2    Kocova, E.3    Rippe, R.A.4    Friedman, S.5
  • 8
    • 77955704597 scopus 로고    scopus 로고
    • Human immunodeficiency virus (HIV)-1 infects human hepatic stellate cells and promotes collagen I and monocyte chemoattractant protein-1 expression: implications for the pathogenesis of HIV/hepatitis C virus-induced liver fibrosis
    • Tuyama AC, Hong F, Saiman Y, Wang C, Ozkok D, et al. (2010) Human immunodeficiency virus (HIV)-1 infects human hepatic stellate cells and promotes collagen I and monocyte chemoattractant protein-1 expression: implications for the pathogenesis of HIV/hepatitis C virus-induced liver fibrosis. Hepatology 52: 612-622.
    • (2010) Hepatology , vol.52 , pp. 612-622
    • Tuyama, A.C.1    Hong, F.2    Saiman, Y.3    Wang, C.4    Ozkok, D.5
  • 9
    • 79151480336 scopus 로고    scopus 로고
    • Expression and functional analysis of endoglin in isolated liver cells and its involvement in fibrogenic Smad signalling
    • Meurer SK, Tihaa L, Borkham-Kamphorst E, Weiskirchen R, (2011) Expression and functional analysis of endoglin in isolated liver cells and its involvement in fibrogenic Smad signalling. Cell Signal 23: 683-699.
    • (2011) Cell Signal , vol.23 , pp. 683-699
    • Meurer, S.K.1    Tihaa, L.2    Borkham-Kamphorst, E.3    Weiskirchen, R.4
  • 10
    • 30044443872 scopus 로고    scopus 로고
    • Leptin enhances alpha1(I) collagen gene expression in LX-2 human hepatic stellate cells through JAK-mediated H2O2-dependent MAPK pathways
    • Cao Q, Mak KM, Lieber CS, (2006) Leptin enhances alpha1(I) collagen gene expression in LX-2 human hepatic stellate cells through JAK-mediated H2O2-dependent MAPK pathways. J Cell Biochem 97: 188-197.
    • (2006) J Cell Biochem , vol.97 , pp. 188-197
    • Cao, Q.1    Mak, K.M.2    Lieber, C.S.3
  • 11
    • 36348939367 scopus 로고    scopus 로고
    • Adenosine A2A receptor occupancy stimulates collagen expression by hepatic stellate cells via pathways involving protein kinase A, Src, and extracellular signal-regulated kinases 1/2 signaling cascade or p38 mitogen-activated protein kinase signaling pathway
    • Che J, Chan ES, Cronstein BN, (2007) Adenosine A2A receptor occupancy stimulates collagen expression by hepatic stellate cells via pathways involving protein kinase A, Src, and extracellular signal-regulated kinases 1/2 signaling cascade or p38 mitogen-activated protein kinase signaling pathway. Mol Pharmacol 72: 1626-1636.
    • (2007) Mol Pharmacol , vol.72 , pp. 1626-1636
    • Che, J.1    Chan, E.S.2    Cronstein, B.N.3
  • 12
    • 79251527482 scopus 로고    scopus 로고
    • Combination of retinoic acid and ursodeoxycholic acid attenuates liver injury in bile duct-ligated rats and human hepatic cells
    • He H, Mennone A, Boyer JL, Cai SY, (2011) Combination of retinoic acid and ursodeoxycholic acid attenuates liver injury in bile duct-ligated rats and human hepatic cells. Hepatology 53: 548-557.
    • (2011) Hepatology , vol.53 , pp. 548-557
    • He, H.1    Mennone, A.2    Boyer, J.L.3    Cai, S.Y.4
  • 13
    • 66249134291 scopus 로고    scopus 로고
    • Biodegradable meshes printed with extracellular matrix proteins support micropatterned hepatocyte cultures
    • Woodrow KA, Wood MJ, Saucier-Sawyer JK, Solbrig C, Saltzman WM, (2009) Biodegradable meshes printed with extracellular matrix proteins support micropatterned hepatocyte cultures. Tissue Eng Part A 15: 1169-1179.
    • (2009) Tissue Eng Part A , vol.15 , pp. 1169-1179
    • Woodrow, K.A.1    Wood, M.J.2    Saucier-Sawyer, J.K.3    Solbrig, C.4    Saltzman, W.M.5
  • 14
    • 79955820751 scopus 로고    scopus 로고
    • Hepatic stellate cells accelerate the malignant behavior of cholangiocarcinoma cells
    • Okabe H, Beppu T, Hayashi H, Ishiko T, Masuda T, et al. (2011) Hepatic stellate cells accelerate the malignant behavior of cholangiocarcinoma cells. Ann Surg Oncol 18: 1175-1184.
    • (2011) Ann Surg Oncol , vol.18 , pp. 1175-1184
    • Okabe, H.1    Beppu, T.2    Hayashi, H.3    Ishiko, T.4    Masuda, T.5
  • 15
    • 78049503283 scopus 로고    scopus 로고
    • Apelin mediates the induction of profibrogenic genes in human hepatic stellate cells
    • Melgar-Lesmes P, Casals G, Pauta M, Ros J, Reichenbach V, et al. (2010) Apelin mediates the induction of profibrogenic genes in human hepatic stellate cells. Endocrinology 151: 5306-5314.
    • (2010) Endocrinology , vol.151 , pp. 5306-5314
    • Melgar-Lesmes, P.1    Casals, G.2    Pauta, M.3    Ros, J.4    Reichenbach, V.5
  • 16
    • 78149455402 scopus 로고    scopus 로고
    • E3 ubiquitin ligase synoviolin is involved in liver fibrogenesis
    • Hasegawa D, Fujii R, Yagishita N, Matsumoto N, Aratani S, et al. (2010) E3 ubiquitin ligase synoviolin is involved in liver fibrogenesis. PLoS ONE 5(10): e13590.
    • (2010) PLoS ONE , vol.5 , Issue.10
    • Hasegawa, D.1    Fujii, R.2    Yagishita, N.3    Matsumoto, N.4    Aratani, S.5
  • 17
    • 0029959861 scopus 로고    scopus 로고
    • A hybrid herpesvirus infectious vector based on Epstein-Barr virus and herpes simplex virus type 1 for gene transfer into human cells in vitro and in vivo
    • Wang S, Vos JM, (1996) A hybrid herpesvirus infectious vector based on Epstein-Barr virus and herpes simplex virus type 1 for gene transfer into human cells in vitro and in vivo. J Virol 70: 8422-8430.
    • (1996) J Virol , vol.70 , pp. 8422-8430
    • Wang, S.1    Vos, J.M.2
  • 18
    • 0019332750 scopus 로고
    • Human hepatocellular carcinoma cell lines secrete the major plasma proteins and hepatitis B surface antigen
    • Knowles BB, Howe CC, Aden DP, (1980) Human hepatocellular carcinoma cell lines secrete the major plasma proteins and hepatitis B surface antigen. Science 209: 497-499.
    • (1980) Science , vol.209 , pp. 497-499
    • Knowles, B.B.1    Howe, C.C.2    Aden, D.P.3
  • 19
    • 0035035514 scopus 로고    scopus 로고
    • Expression of isoforms and splice variants of the latent transforming growth factor beta binding protein (LTBP) in cultured human liver myofibroblasts
    • Mangasser-Stephan K, Gartung C, Lahme B, Gressner AM, (2001) Expression of isoforms and splice variants of the latent transforming growth factor beta binding protein (LTBP) in cultured human liver myofibroblasts. Liver 21: 105-113.
    • (2001) Liver , vol.21 , pp. 105-113
    • Mangasser-Stephan, K.1    Gartung, C.2    Lahme, B.3    Gressner, A.M.4
  • 21
    • 0344622606 scopus 로고
    • The serial cultivation of human diploid cell strains
    • Hayflick L, Moorhead PS, (1961) The serial cultivation of human diploid cell strains. Exp Cell Res 25: 585-621.
    • (1961) Exp Cell Res , vol.25 , pp. 585-621
    • Hayflick, L.1    Moorhead, P.S.2
  • 22
    • 0002889389 scopus 로고
    • SV40-induced transformation of human diploid cells: crisis and recovery
    • Girardi AJ, Jensen FC, Koprowski H, (1965) SV40-induced transformation of human diploid cells: crisis and recovery. J Cell Physiol 65: 69-83.
    • (1965) J Cell Physiol , vol.65 , pp. 69-83
    • Girardi, A.J.1    Jensen, F.C.2    Koprowski, H.3
  • 23
    • 78651238599 scopus 로고    scopus 로고
    • CCN proteins in normal and injured liver
    • Weiskirchen R, (2011) CCN proteins in normal and injured liver. Front Biosci 16: 1939-1961.
    • (2011) Front Biosci , vol.16 , pp. 1939-1961
    • Weiskirchen, R.1
  • 24
    • 84860228100 scopus 로고    scopus 로고
    • BMP-7/TGF-β1 signalling in myoblasts: components involved in signalling and BMP-7-dependent blockage of TGF-β-mediated CTGF expression
    • Meurer SK, Esser M, Tihaa L, Weiskirchen R, (2012) BMP-7/TGF-β1 signalling in myoblasts: components involved in signalling and BMP-7-dependent blockage of TGF-β-mediated CTGF expression. Eur J Cell Biol 91: 450-463.
    • (2012) Eur J Cell Biol , vol.91 , pp. 450-463
    • Meurer, S.K.1    Esser, M.2    Tihaa, L.3    Weiskirchen, R.4
  • 25
    • 13244249796 scopus 로고    scopus 로고
    • Identification of endoglin in rat hepatic stellate cells: new insights into transforming growth factor β receptor signaling
    • Meurer SK, Tihaa L, Lahme B, Gressner AM, Weiskirchen R, (2005) Identification of endoglin in rat hepatic stellate cells: new insights into transforming growth factor β receptor signaling. J Biol Chem 280: 3078-3087.
    • (2005) J Biol Chem , vol.280 , pp. 3078-3087
    • Meurer, S.K.1    Tihaa, L.2    Lahme, B.3    Gressner, A.M.4    Weiskirchen, R.5
  • 26
  • 27
    • 0004629582 scopus 로고
    • Results of species-specific hemagglutination tests on "transformed," nontransformed, and primary cell cultures
    • Brand KG, Syverton JT, (1962) Results of species-specific hemagglutination tests on "transformed," nontransformed, and primary cell cultures. J Natl Cancer Inst 28: 147-157.
    • (1962) J Natl Cancer Inst , vol.28 , pp. 147-157
    • Brand, K.G.1    Syverton, J.T.2
  • 28
    • 0014129108 scopus 로고
    • Genetic markers as tracers in cell culture
    • Gartler SM, (1967) Genetic markers as tracers in cell culture. Natl Cancer Inst Monogr 26: 167-195.
    • (1967) Natl Cancer Inst Monogr , vol.26 , pp. 167-195
    • Gartler, S.M.1
  • 29
    • 33847126553 scopus 로고    scopus 로고
    • Cell biology. Cases of mistaken identity
    • Chatterjee R, (2007) Cell biology. Cases of mistaken identity. Science 315: 928-931.
    • (2007) Science , vol.315 , pp. 928-931
    • Chatterjee, R.1
  • 30
    • 78649323066 scopus 로고    scopus 로고
    • Recommendation of short tandem repeat profiling for authenticating human cell lines, stem cells, and tissues
    • Barallon R, Bauer SR, Butler J, Capes-Davis A, Dirks WG, et al. (2010) Recommendation of short tandem repeat profiling for authenticating human cell lines, stem cells, and tissues. In Vitro Cell Dev Biol Anim 46: 727-732.
    • (2010) In Vitro Cell Dev Biol Anim , vol.46 , pp. 727-732
    • Barallon, R.1    Bauer, S.R.2    Butler, J.3    Capes-Davis, A.4    Dirks, W.G.5
  • 31
    • 77952950455 scopus 로고    scopus 로고
    • Cell line misidentification: the beginning of the end
    • American Type Culture Collection Standards Development Organization Workgroup ASN-0002
    • American Type Culture Collection Standards Development Organization Workgroup ASN-0002 (2010) Cell line misidentification: the beginning of the end. Nat Rev Cancer 10: 441-448.
    • (2010) Nat Rev Cancer , vol.10 , pp. 441-448
  • 32
    • 80055061886 scopus 로고    scopus 로고
    • Cell line misidentification: the case of the Chang liver cell line
    • Gao Q, Wang XY, Zhou J, Fan J, (2011) Cell line misidentification: the case of the Chang liver cell line. Hepatology 54: 1894-1895.
    • (2011) Hepatology , vol.54 , pp. 1894-1895
    • Gao, Q.1    Wang, X.Y.2    Zhou, J.3    Fan, J.4
  • 34
    • 37749010294 scopus 로고    scopus 로고
    • Eradication of cross-contaminated cell lines: a call for action
    • Nardone RM, (2007) Eradication of cross-contaminated cell lines: a call for action. Cell Biol Toxicol 23: 367-372.
    • (2007) Cell Biol Toxicol , vol.23 , pp. 367-372
    • Nardone, R.M.1
  • 35
    • 0034934077 scopus 로고    scopus 로고
    • Short tandem repeat profiling provides an international reference standard for human cell lines
    • Masters JR, Thomson JA, Daly-Burns B, Reid YA, Dirks WG, et al. (2001) Short tandem repeat profiling provides an international reference standard for human cell lines. Proc Natl Acad Sci U S A 98: 8012-8017.
    • (2001) Proc Natl Acad Sci U S A , vol.98 , pp. 8012-8017
    • Masters, J.R.1    Thomson, J.A.2    Daly-Burns, B.3    Reid, Y.A.4    Dirks, W.G.5


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