Parallel assessment of globin lentiviral transfer in induced pluripotent stem cells and adult hematopoietic stem cells derived from the same transplanted β-thalassemia patient

Stem Cells

Volumn 31, Issue 9, 2013, Pages 1785-1794

  Tubsuwan, Alisa ^a,b,c,d   Abed, Soumeya ^a,b,e   Deichmann, Annette ^f   Kardel, Melanie D ^g   Bartholomä, Cynthia ^f   Cheung, Alice ^g   Negre, Olivier ^a,b,h   Kadri, Zahra ^a,b   Fucharoen, Suthat ^c,d   Von Kalle, Christof ^f   Payen, Emmanuel ^a,b   Chrétien, Stany ^a,b   Schmidt, Manfred ^f   Eaves, Connie J ^g   Leboulch, Philippe ^a,b,h,i   Maouche Chrétien, Leïla ^a,b  

^a INSTITUT DE RADIOPROTECTION ET DE SÛRETÉ NUCLÉAIRE   (France)

^b Institute of Emerging Diseases and Innovative Therapies   (France)

^c MAHIDOL UNIVERSITY   (Thailand)

^d MAHIDOL UNIVERSITY   (Thailand)

^e UNIVERSITÉ PARIS DESCARTES   (France)

^f GERMAN CANCER RESEARCH CENTER DKFZ   (Germany)

^g BRITISH COLUMBIA CANCER AGENCY   (Canada)

^h Bluebirdbio France ^*  (France)

ⁱ BRIGHAM AND WOMEN S HOSPITAL   (United States)

Author keywords

Human induced pluripotent stem cells Gene therapy Hematopoietic stem cells Thalassemia Globin expression

Indexed keywords

GLOBIN; HIGH MOBILITY GROUP A2 PROTEIN; LENTIVIRUS VECTOR;

ADRENOLEUKODYSTROPHY; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BETA THALASSEMIA; CARCINOGENESIS; CELL REGENERATION; CELL TRANSPLANTATION; CONTROLLED STUDY; ERYTHROID CELL; GENE CONTROL; GENE EXPRESSION; GENOTOXICITY; HEMATOPOIETIC STEM CELL; HEMOGLOBINOPATHY; MOUSE; NONHUMAN; PLURIPOTENT STEM CELL; VIRAL GENE DELIVERY SYSTEM;

HUMAN INDUCED PLURIPOTENT STEM CELLS GENE THERAPY HEMATOPOIETIC STEM CELLS THALASSEMIA Β-GLOBIN EXPRESSION;

ADULT; ANIMALS; BETA-THALASSEMIA; CELL DIFFERENTIATION; ERYTHROID CELLS; GENE EXPRESSION REGULATION; GENETIC VECTORS; GLOBINS; HEMATOPOIETIC STEM CELL TRANSPLANTATION; HEMATOPOIETIC STEM CELLS; HUMANS; INDUCED PLURIPOTENT STEM CELLS; LENTIVIRUS; MICE; MUTAGENS; REGENERATION; TRANSDUCTION, GENETIC; VIRUS INTEGRATION;

EID: 84885145569     PISSN: 10665099     EISSN: None     Source Type: Journal    
DOI: 10.1002/stem.1436     Document Type: Article

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