메뉴 건너뛰기




Volumn 288, Issue 40, 2013, Pages 29193-29205

Cross-talk from β-adrenergic receptors modulates α2A -adrenergic receptor endocytosis in sympathetic neurons via protein kinase A and spinophilin

Author keywords

[No Author keywords available]

Indexed keywords

MOLECULAR BIOLOGY;

EID: 84885143688     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M113.469494     Document Type: Article
Times cited : (10)

References (48)
  • 2
    • 33747585593 scopus 로고    scopus 로고
    • 2C-Adrenergic receptors exhibit enhanced surface expression and signaling upon association with 2-adrenergic receptors
    • Prinster, S. C., Holmqvist, T. G., and Hall, R. A. (2006) 2C-Adrenergic receptors exhibit enhanced surface expression and signaling upon association with 2-adrenergic receptors. J. Pharmacol. Exp. Ther. 318, 974-981
    • (2006) J. Pharmacol. Exp. Ther. , vol.318 , pp. 974-981
    • Prinster, S.C.1    Holmqvist, T.G.2    Hall, R.A.3
  • 3
    • 0037352887 scopus 로고    scopus 로고
    • Desensitization of 2A-adrenoceptor signalling by modest levels of adrenaline is facilitated by 2-adrenoceptor-dependent GRK3 up-regulation
    • Bawa, T., Altememi, G. F., Eikenburg, D. C., and Standifer, K. M. (2003) Desensitization of 2A-adrenoceptor signalling by modest levels of adrenaline is facilitated by 2-adrenoceptor-dependent GRK3 up-regulation. Br. J. Pharmacol. 138, 921-931
    • (2003) Br. J. Pharmacol. , vol.138 , pp. 921-931
    • Bawa, T.1    Altememi, G.F.2    Eikenburg, D.C.3    Standifer, K.M.4
  • 4
    • 39049161159 scopus 로고    scopus 로고
    • The presence of 2-adrenoceptors sensitizes 2A-adrenoceptors to desensitization after chronic epinephrine treatment
    • Bawa-Khalfe, T., Altememi, G. F., Mandyam, C. D., Schwarz, L. A., Eikenburg, D. C., and Standifer, K. M. (2007) The presence of 2-adrenoceptors sensitizes 2A-adrenoceptors to desensitization after chronic epinephrine treatment. BMC Pharmacol. 7, 16
    • (2007) BMC Pharmacol. , vol.7 , pp. 16
    • Bawa-Khalfe, T.1    Altememi, G.F.2    Mandyam, C.D.3    Schwarz, L.A.4    Eikenburg, D.C.5    Standifer, K.M.6
  • 5
    • 6344229316 scopus 로고    scopus 로고
    • Simultaneous 2B-and 2-adrenoceptor activation sensitizes the 2B-adrenoceptor for agonist-induced down-regulation
    • Desai, A. N., Standifer, K. M., and Eikenburg, D. C. (2004) Simultaneous 2B-and 2-adrenoceptor activation sensitizes the 2B-adrenoceptor for agonist-induced down-regulation. J. Pharmacol. Exp. Ther. 311, 794-802
    • (2004) J. Pharmacol. Exp. Ther. , vol.311 , pp. 794-802
    • Desai, A.N.1    Standifer, K.M.2    Eikenburg, D.C.3
  • 6
    • 0018895964 scopus 로고
    • Adrenergic regulation of2-adrenergic receptors in the central nervous system
    • Maggi, A., U'Prichard, D. C., and Enna, S. J. (1980)-Adrenergic regulation of2-adrenergic receptors in the central nervous system. Science 207, 645-647
    • (1980) Science , vol.207 , pp. 645-647
    • Maggi, A.1    U'Prichard, D.C.2    Enna, S.J.3
  • 7
    • 0021274727 scopus 로고
    • The interaction between-and 2-adrenoceptors in cerebral cortical membranes. Isoproterenol-induced increase in [3H]clonidine binding in rats
    • Nomura, Y., Kawai, M., and Segawa, T. (1984) The interaction between-and 2-adrenoceptors in cerebral cortical membranes. Isoproterenol-induced increase in [3H]clonidine binding in rats. Brain Res. 302, 101-109
    • (1984) Brain Res. , vol.302 , pp. 101-109
    • Nomura, Y.1    Kawai, M.2    Segawa, T.3
  • 8
    • 0026029391 scopus 로고
    • Interaction between 2-and-adrenergic receptors in rat cerebral cortical membranes. Clonidine-induced reduction in agonist and antagonist affinity for-adrenergic receptors
    • Nakamura, T., Tsujimura, R., and Nomura, J. (1991) Interaction between 2-and-adrenergic receptors in rat cerebral cortical membranes. Clonidine-induced reduction in agonist and antagonist affinity for-adrenergic receptors. Brain Res. 542, 181-186
    • (1991) Brain Res. , vol.542 , pp. 181-186
    • Nakamura, T.1    Tsujimura, R.2    Nomura, J.3
  • 9
    • 0029989950 scopus 로고    scopus 로고
    • Interaction between-and-adrenergic receptor agonists modulating the slow Ca2+-activated K+ current IAHP in hippocampal neurons
    • Pedarzani, P., and Storm, J. F. (1996) Interaction between-and-adrenergic receptor agonists modulating the slow Ca2+-activated K+ current IAHP in hippocampal neurons. Eur. J. Neurosci. 8, 2098-2110
    • (1996) Eur. J. Neurosci. , vol.8 , pp. 2098-2110
    • Pedarzani, P.1    Storm, J.F.2
  • 10
    • 0027722294 scopus 로고
    • PKA mediates the effects of monoamine transmitters on the K+ current underlying the slow spike frequency adaptation in hippocampal neurons
    • Pedarzani, P., and Storm, J. F. (1993) PKA mediates the effects of monoamine transmitters on the K+ current underlying the slow spike frequency adaptation in hippocampal neurons. Neuron. 11, 1023-1035
    • (1993) Neuron. , vol.11 , pp. 1023-1035
    • Pedarzani, P.1    Storm, J.F.2
  • 11
    • 0021995606 scopus 로고
    • Clonidine pretreatment enhances the sensitivity of the-noradrenergic receptor coupled adenylate cyclase system in astrocytes
    • Northam, W. J., and Mobley, P. (1985) Clonidine pretreatment enhances the sensitivity of the-noradrenergic receptor coupled adenylate cyclase system in astrocytes. Eur. J. Pharmacol. 113, 153-154
    • (1985) Eur. J. Pharmacol. , vol.113 , pp. 153-154
    • Northam, W.J.1    Mobley, P.2
  • 12
    • 0027104739 scopus 로고
    • Preferential desensitization of-versus 2-adrenergic receptors accelerates loss of response to norepinephrine in primary glial cultures
    • Atkinson, B. N., and Minneman, K. P. (1992) Preferential desensitization of-versus 2-adrenergic receptors accelerates loss of response to norepinephrine in primary glial cultures. Mol. Pharmacol. 41, 688-694
    • (1992) Mol. Pharmacol. , vol.41 , pp. 688-694
    • Atkinson, B.N.1    Minneman, K.P.2
  • 13
    • 0030435116 scopus 로고    scopus 로고
    • Prejunctional adrenoceptor desensitization in rat heart after chronic epinephrine treatment
    • Apparsundaram, S., and Eikenburg, D. C. (1996) Prejunctional adrenoceptor desensitization in rat heart after chronic epinephrine treatment. J. Pharmacol. Exp. Ther. 278, 862-870
    • (1996) J. Pharmacol. Exp. Ther. , vol.278 , pp. 862-870
    • Apparsundaram, S.1    Eikenburg, D.C.2
  • 16
    • 84857051837 scopus 로고    scopus 로고
    • Neurotransmission. The autonomic and somatic motor nervous systems
    • online edition (Brunton, L. L., ed) 12th Ed., McGraw-Hill Inc., New York
    • Westfall, T. C., and Westfall, D. P. (2011) Neurotransmission. The autonomic and somatic motor nervous systems, in Goodman & Gilman's The Pharmacological Basis of Therapeutics, online edition (Brunton, L. L., ed) 12th Ed., McGraw-Hill Inc., New York
    • (2011) Goodman & Gilman's the Pharmacological Basis of Therapeutics
    • Westfall, T.C.1    Westfall, D.P.2
  • 18
    • 0030922920 scopus 로고    scopus 로고
    • Spinophilin, a novel protein phosphatase 1 binding protein localized to dendritic spines
    • Allen, P. B., Ouimet, C. C., and Greengard, P. (1997) Spinophilin, a novel protein phosphatase 1 binding protein localized to dendritic spines. Proc. Natl. Acad. Sci. U.S.A. 94, 9956-9961
    • (1997) Proc. Natl. Acad. Sci. U.S.A. , vol.94 , pp. 9956-9961
    • Allen, P.B.1    Ouimet, C.C.2    Greengard, P.3
  • 21
    • 0037184945 scopus 로고    scopus 로고
    • Regulated interactions of the 2A adrenergic receptor with spinophilin, 14-3-3, and arrestin 3
    • Wang, Q., and Limbird, L. E. (2002) Regulated interactions of the 2A adrenergic receptor with spinophilin, 14-3-3, and arrestin 3. J. Biol. Chem. 277, 50589-50596
    • (2002) J. Biol. Chem. , vol.277 , pp. 50589-50596
    • Wang, Q.1    Limbird, L.E.2
  • 22
    • 17844410054 scopus 로고    scopus 로고
    • 2-adrenergic agonist enrichment of spinophilin at the cell surface involves subunits ofGi proteins and is preferentially induced by the 2A-subtype
    • Brady, A. E., Wang, Q., Allen, P. B., Rizzo, M., Greengard, P., and Limbird, L. E. (2005) 2-adrenergic agonist enrichment of spinophilin at the cell surface involves subunits ofGi proteins and is preferentially induced by the 2A-subtype. Mol. Pharmacol. 67, 1690-1696
    • (2005) Mol. Pharmacol. , vol.67 , pp. 1690-1696
    • Brady, A.E.1    Wang, Q.2    Allen, P.B.3    Rizzo, M.4    Greengard, P.5    Limbird, L.E.6
  • 23
  • 25
    • 77954902976 scopus 로고    scopus 로고
    • Enhanced hypotensive, bradycardic, and hypnotic responses to 2-adrenergic agonists in spinophilin-null mice are accompanied by increased G protein coupling to the 2A-adrenergic receptor
    • Lu, R., Chen, Y., Cottingham, C., Peng, N., Jiao, K., Limbird, L. E., Wyss, J. M., and Wang, Q. (2010) Enhanced hypotensive, bradycardic, and hypnotic responses to 2-adrenergic agonists in spinophilin-null mice are accompanied by increased G protein coupling to the 2A-adrenergic receptor. Mol. Pharmacol. 78, 279-286
    • (2010) Mol. Pharmacol. , vol.78 , pp. 279-286
    • Lu, R.1    Chen, Y.2    Cottingham, C.3    Peng, N.4    Jiao, K.5    Limbird, L.E.6    Wyss, J.M.7    Wang, Q.8
  • 26
    • 84871904171 scopus 로고    scopus 로고
    • Noradrenergic antidepressant responses to desipramine in vivo are reciprocally regulated by arrestin3 and spinophilin
    • Cottingham, C., Li, X., and Wang, Q. (2012) Noradrenergic antidepressant responses to desipramine in vivo are reciprocally regulated by arrestin3 and spinophilin. Neuropharmacology 62, 2354-2362
    • (2012) Neuropharmacology , vol.62 , pp. 2354-2362
    • Cottingham, C.1    Li, X.2    Wang, Q.3
  • 28
    • 47249114403 scopus 로고    scopus 로고
    • Protein kinase A phosphorylation of spinophilin modulates its interaction with the 2A-adrenergic receptor (AR) and alters temporal properties of 2AAR internalization
    • Xu, J., Chen, Y., Lu, R., Cottingham, C., Jiao, K., and Wang, Q. (2008) Protein kinase A phosphorylation of spinophilin modulates its interaction with the 2A-adrenergic receptor (AR) and alters temporal properties of 2AAR internalization. J. Biol. Chem. 283, 14516-14523
    • (2008) J. Biol. Chem. , vol.283 , pp. 14516-14523
    • Xu, J.1    Chen, Y.2    Lu, R.3    Cottingham, C.4    Jiao, K.5    Wang, Q.6
  • 29
    • 79954425389 scopus 로고    scopus 로고
    • Structural insights into adrenergic receptor function and pharmacology
    • Kobilka, B. K. (2011) Structural insights into adrenergic receptor function and pharmacology. Trends Pharmacol. Sci. 32, 213-218
    • (2011) Trends Pharmacol. Sci. , vol.32 , pp. 213-218
    • Kobilka, B.K.1
  • 30
    • 67649713896 scopus 로고    scopus 로고
    • Epitope-tagged receptor knock-in mice reveal that differential desensitization of 2-adrenergic responses is because of ligand-selective internalization
    • Lu, R., Li, Y., Zhang, Y., Chen, Y., Shields, A. D., Winder, D. G., Angelotti, T., Jiao, K., Limbird, L. E., Zhou, Y., and Wang, Q. (2009) Epitope-tagged receptor knock-in mice reveal that differential desensitization of 2-adrenergic responses is because of ligand-selective internalization. J. Biol. Chem. 284, 13233-13243
    • (2009) J. Biol. Chem. , vol.284 , pp. 13233-13243
    • Lu, R.1    Li, Y.2    Zhang, Y.3    Chen, Y.4    Shields, A.D.5    Winder, D.G.6    Angelotti, T.7    Jiao, K.8    Limbird, L.E.9    Zhou, Y.10    Wang, Q.11
  • 31
    • 0015581729 scopus 로고
    • Catecholamine loading and depletion in the rat superior cervical ganglion. A formol fluorescence and enzyme histochemical study with numerical assessments
    • Yamauchi, A., Lever, J. D., and Kemp, K. W. (1973) Catecholamine loading and depletion in the rat superior cervical ganglion. A formol fluorescence and enzyme histochemical study with numerical assessments. J. Anat. 114, 271-282
    • (1973) J. Anat. , vol.114 , pp. 271-282
    • Yamauchi, A.1    Lever, J.D.2    Kemp, K.W.3
  • 32
    • 41149090339 scopus 로고    scopus 로고
    • Regulation of GPCRs by endocytic membrane trafficking and its potential implications
    • Hanyaloglu, A. C., and von Zastrow, M. (2008) Regulation of GPCRs by endocytic membrane trafficking and its potential implications. Annu. Rev. Pharmacol. Toxicol. 48, 537-568
    • (2008) Annu. Rev. Pharmacol. Toxicol. , vol.48 , pp. 537-568
    • Hanyaloglu, A.C.1    Von Zastrow, M.2
  • 33
    • 84867135368 scopus 로고    scopus 로고
    • Modulating neuromodulation by receptor membrane traffic in the endocytic pathway
    • von Zastrow, M., and Williams, J. T. (2012) Modulating neuromodulation by receptor membrane traffic in the endocytic pathway. Neuron. 76, 22-32
    • (2012) Neuron. , vol.76 , pp. 22-32
    • Von Zastrow, M.1    Williams, J.T.2
  • 34
    • 80053927094 scopus 로고    scopus 로고
    • The antidepressant desipramine is an arrestin-biased ligand at the 2A-adrenergic receptor driving receptor down-regulation in vitro and in vivo
    • Cottingham, C., Chen, Y., Jiao, K., and Wang, Q. (2011) The antidepressant desipramine is an arrestin-biased ligand at the 2A-adrenergic receptor driving receptor down-regulation in vitro and in vivo. J. Biol. Chem. 286, 36063-36075
    • (2011) J. Biol. Chem. , vol.286 , pp. 36063-36075
    • Cottingham, C.1    Chen, Y.2    Jiao, K.3    Wang, Q.4
  • 37
    • 33747032525 scopus 로고    scopus 로고
    • Differential targeting and function of 2A and 2C adrenergic receptor subtypes in cultured sympathetic neurons
    • Brum, P. C., Hurt, C. M., Shcherbakova, O. G., Kobilka, B., and Angelotti, T. (2006) Differential targeting and function of 2A and 2C adrenergic receptor subtypes in cultured sympathetic neurons. Neuropharmacology 51, 397-413
    • (2006) Neuropharmacology , vol.51 , pp. 397-413
    • Brum, P.C.1    Hurt, C.M.2    Shcherbakova, O.G.3    Kobilka, B.4    Angelotti, T.5
  • 38
    • 0024353865 scopus 로고
    • Primary structural determinants essential for potent inhibition of cAMP-dependent protein kinase by inhibitory peptides corresponding to the active portion of the heat-stable inhibitor protein
    • Glass, D. B., Cheng, H. C., Mende-Mueller, L., Reed, J., and Walsh, D. A. (1989) Primary structural determinants essential for potent inhibition of cAMP-dependent protein kinase by inhibitory peptides corresponding to the active portion of the heat-stable inhibitor protein. J. Biol. Chem. 264, 8802-8810
    • (1989) J. Biol. Chem. , vol.264 , pp. 8802-8810
    • Glass, D.B.1    Cheng, H.C.2    Mende-Mueller, L.3    Reed, J.4    Walsh, D.A.5
  • 41
    • 0242721361 scopus 로고    scopus 로고
    • Multifaceted roles of-arrestins in the regulation of seven-membrane- spanning receptor trafficking and signalling
    • Shenoy, S. K., and Lefkowitz, R. J. (2003) Multifaceted roles of-arrestins in the regulation of seven-membrane-spanning receptor trafficking and signalling. Biochem. J. 375, 503-515
    • (2003) Biochem. J. , vol.375 , pp. 503-515
    • Shenoy, S.K.1    Lefkowitz, R.J.2
  • 43
    • 84869137015 scopus 로고    scopus 로고
    • Adrenoceptor agonists & sympathomimetic drugs
    • (Katzung, B. G., Masters, S. B., and Trevor, A. J., eds) 12th Ed., McGraw-Hill Inc., New York
    • Biaggioni, I., and Robertson, D. (2012) Adrenoceptor agonists & sympathomimetic drugs, in Basic&Clinical Pharmacology (Katzung, B. G., Masters, S. B., and Trevor, A. J., eds) 12th Ed., McGraw-Hill Inc., New York
    • (2012) Basic&Clinical Pharmacology
    • Biaggioni, I.1    Robertson, D.2
  • 44
    • 41549159062 scopus 로고    scopus 로고
    • Adrenoceptor antagonist drugs
    • (Katzung, B. G., Masters, S. B., and Trevor, A. J., eds) 12th Ed., McGraw-Hill Inc., New York
    • Robertson, D., and Biaggioni, I. (2012) Adrenoceptor antagonist drugs, in Basic & Clinical Pharmacology (Katzung, B. G., Masters, S. B., and Trevor, A. J., eds) 12th Ed., McGraw-Hill Inc., New York
    • (2012) Basic & Clinical Pharmacology
    • Robertson, D.1    Biaggioni, I.2
  • 46
    • 7544225524 scopus 로고    scopus 로고
    • Cellular and subcellular distribution of spinophilin, a PP1 regulatory protein that bundles F-actin in dendritic spines
    • Ouimet, C. C., Katona, I., Allen, P., Freund, T. F., and Greengard, P. (2004) Cellular and subcellular distribution of spinophilin, a PP1 regulatory protein that bundles F-actin in dendritic spines. J. Comp. Neurol. 479, 374-388
    • (2004) J. Comp. Neurol. , vol.479 , pp. 374-388
    • Ouimet, C.C.1    Katona, I.2    Allen, P.3    Freund, T.F.4    Greengard, P.5
  • 47
    • 0347719684 scopus 로고    scopus 로고
    • Subcellular distribution of spinophilin immunolabeling in primate prefrontal cortex. Localization to and within dendritic spines
    • Muly, E. C., Smith, Y., Allen, P., and Greengard, P. (2004) Subcellular distribution of spinophilin immunolabeling in primate prefrontal cortex. Localization to and within dendritic spines. J. Comp. Neurol. 469, 185-197
    • (2004) J. Comp. Neurol. , vol.469 , pp. 185-197
    • Muly, E.C.1    Smith, Y.2    Allen, P.3    Greengard, P.4
  • 48
    • 77953168124 scopus 로고    scopus 로고
    • Identification and validation of novel spinophilin-associated proteins in rodent striatum using an enhanced ex vivo shotgun proteomics approach
    • Baucum, A. J., 2nd, Jalan-Sakrikar, N., Jiao, Y., Gustin, R. M., Carmody, L. C., Tabb, D. L., Ham, A. J., and Colbran, R. J. (2010) Identification and validation of novel spinophilin-associated proteins in rodent striatum using an enhanced ex vivo shotgun proteomics approach. Mol. Cell Proteomics 9, 1243-1259
    • (2010) Mol. Cell Proteomics , vol.9 , pp. 1243-1259
    • Baucum, I.I.A.J.1    Jalan-Sakrikar, N.2    Jiao, Y.3    Gustin, R.M.4    Carmody, L.C.5    Tabb, D.L.6    Ham, A.J.7    Colbran, R.J.8


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.