The presence of β2-adrenoceptors sensitizes α2A-adrenoceptors to desensitization after chronic epinephrine treatment

BMC Pharmacology

Volumn 7, Issue , 2007, Pages

  Bawa Khalfe, Tasneem ^a,d   Altememi, Ghazi F ^d   Mandyam, Chitra D ^b,d   Schwarz, Lindsay A ^d   Eikenburg, Douglas C ^d   Standifer, Kelly M ^c,d  

^a UNIVERSITY OF TEXAS MEDICAL SCHOOL   (United States)

^b SCRIPPS RESEARCH INSTITUTE   (United States)

^c UNIVERSITY OF OKLAHOMA HEALTH SCIENCES CENTER   (United States)

^d UNIVERSITY OF HOUSTON   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ADRENALIN; ALPHA 2A ADRENERGIC RECEPTOR; BETA 2 ADRENERGIC RECEPTOR; CYCLIC AMP; G PROTEIN COUPLED RECEPTOR KINASE 2; G PROTEIN COUPLED RECEPTOR KINASE 3; UNCLASSIFIED DRUG; ADRBK1 PROTEIN, HUMAN; ADRBK2 PROTEIN, HUMAN; ALPHA 2 ADRENERGIC RECEPTOR; ALPHA ADRENERGIC RECEPTOR STIMULATING AGENT; BRIMONIDINE; MESSENGER RNA; NORADRENALIN; PROPRANOLOL; QUINOXALINE DERIVATIVE; RECEPTOR, ADRENERGIC, ALPHA 2A; RECEPTOR, ADRENERGIC, ALPHA-2A;

ARTICLE; CONCENTRATION RESPONSE; CONTROLLED STUDY; DESENSITIZATION; DRUG EXPOSURE; GENE EXPRESSION REGULATION; GENETIC TRANSFECTION; HUMAN; HUMAN CELL; LONG TERM EXPOSURE; NEUROBLASTOMA CELL; PROTEIN EXPRESSION; PROTEIN FUNCTION; RECEPTOR BINDING; RECEPTOR DOWN REGULATION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SENSITIVITY ANALYSIS; CELL MEMBRANE; DRUG ANTAGONISM; DRUG POTENTIATION; GENETICS; METABOLISM; TUMOR CELL LINE;

ADRENERGIC ALPHA-AGONISTS; CELL LINE, TUMOR; CELL MEMBRANE; CYCLIC AMP; EPINEPHRINE; G-PROTEIN-COUPLED RECEPTOR KINASE 2; G-PROTEIN-COUPLED RECEPTOR KINASE 3; HUMANS; NOREPINEPHRINE; PROPRANOLOL; QUINOXALINES; RECEPTORS, ADRENERGIC, ALPHA-2; RECEPTORS, ADRENERGIC, BETA-2; RNA, MESSENGER; TRANSFECTION;

EID: 39049161159     PISSN: None     EISSN: 14712210     Source Type: Journal    
DOI: 10.1186/1471-2210-7-16     Document Type: Article

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