The expression status of G protein-coupled receptor GPR30 is associated with the clinical characteristics of endometriosis

Endocrine Research

Volumn 38, Issue 4, 2013, Pages 223-231

  Yuguchi, Hiroko ^a   Tanabe, Akiko ^a   Hayashi, Atsushi ^a   Tanaka, Yoshimichi ^a   Okuda, Kiyoji ^a   Yamashita, Yoshiki ^a   Terai, Yoshito ^a   Ohmichi, Masahide ^a  

^a OSAKA MEDICAL COLLEGE   (Japan)

Author keywords

Ectopic endometrium; Eutopic endometrium; GnRH agonist; GPR30; Leuprolide acetate; Menstrual cycle; Ovarian endometrioma

Indexed keywords

G PROTEIN COUPLED RECEPTOR 30; GONADORELIN AGONIST; LEUPRORELIN; MESSENGER RNA;

ARTICLE; CLINICAL ARTICLE; CLINICAL FEATURE; CONTROLLED STUDY; ENDOMETRIOSIS; ENDOMETRIUM; EPITHELIUM CELL; FEMALE; GENE EXPRESSION; HISTOPATHOLOGY; HUMAN; HUMAN TISSUE; IMMUNOHISTOCHEMISTRY; IMMUNOREACTIVITY; LAPAROSCOPIC SURGERY; MENSTRUAL CYCLE; PATHOGENESIS; PELVIC PAIN; PRIORITY JOURNAL; PROTEIN EXPRESSION; QUANTITATIVE ANALYSIS; REAL TIME POLYMERASE CHAIN REACTION; UTERUS MYOMA; VISUAL ANALOG SCALE;

ADULT; ENDOMETRIOSIS; ENDOMETRIUM; FEMALE; FOLLICULAR PHASE; GENE EXPRESSION; GONADOTROPIN-RELEASING HORMONE; HUMANS; IMMUNOHISTOCHEMISTRY; LEUPROLIDE; LUTEAL PHASE; MIDDLE AGED; REAL-TIME POLYMERASE CHAIN REACTION; RECEPTORS, ESTROGEN; RECEPTORS, G-PROTEIN-COUPLED; RNA, MESSENGER;

EID: 84885139042     PISSN: 07435800     EISSN: None     Source Type: Journal    
DOI: 10.3109/07435800.2013.774011     Document Type: Article

References (37)

1. Giudice LC, Kao LC. Endometriosis. Lancet 2004;364(9447):1789-1799
2. Eskenazi B, Warner ML. Epidemiology of endometriosis. Obstet Gynecol Clin North Am 1997;24(2):235-258
3. Thomas EJ. Endometriosis, 1995 - confusion or sense? Int J Gynaecol Obstet 1995;48(2):149-155
4. Nilsson S, Makela S, Treuter E, et al. Mechanisms of estrogen action. Physiol Rev 2001;81(4):1535-1565
5. Ryan IP, Taylor RN. Endometriosis and infertility: New concepts. Obstet Gynecol Surv 1997;52(6):365-371
6. Bruner KL, Matrisian LM, Rodgers WH, Gorstein F, Osteen KG. Suppression of matrix metalloproteinases inhibits establishment of ectopic lesions by human endometrium in nude mice. J Clin Invest 1997;99(12):2851-2857
7. Sun HS, Hsiao KY, Hsu CC,WuMH, Tsai SJ. Transactivation of steroidogenic acute regulatory protein in human endometriotic stromal cells is mediated by the prostaglandin EP2 receptor. Endocrinology 2003;144(9):3934-3942
8. Tsai SJ, Wu MH, Lin CC, Sun HS, Chen HM. Regulation of steroidogenic acute regulatory protein expression and progesterone production in endometriotic stromal cells. J Clin Endocrinol Metab 2001;86(12):5765-5773
9. Olive DL, Pritts EA. Treatment of endometriosis. N Engl J Med 2001;345(4):266-275
10. Improta-Brears T, Whorton AR, Codazzi F, York JD, Meyer T, McDonnell DP. Estrogen-induced activation of mitogen-activated protein kinase requires mobilization of intracellular calcium. Proc Natl Acad Sci U S A 1999;96(8):4686-4691
11. Revelli A, Massobrio M, Tesarik J. Nongenomic actions of steroid hormones in reproductive tissues. Endocr Rev 1998;19(1):3-17
12. Filardo EJ, Quinn JA, Bland KI, Frackelton AR Jr. Estrogen-induced activation of Erk-1 and Erk-2 requires the G protein-coupled receptor homolog, GPR30, and occurs via trans-activation of the epidermal growth factor receptor through release of HB-EGF. Mol Endocrinol 2000;14(10):1649-1660
13. Revankar CM, Cimino DF, Sklar LA, Arterburn JB, Prossnitz ER. A transmembrane intracellular estrogen receptor mediates rapid cell signaling. Science 2005;307(5715):1625-1630
14. Filardo EJ, Thomas P. GPR30: A seven-transmembrane-spanning estrogen receptor that triggers EGF release. Trends Endocrinol Metab 2005;16(8):362-367
15. Prossnitz ER, Arterburn JB, Smith HO, Oprea TI, Sklar LA, Hathaway HJ. Estrogen signaling through the transmembrane G protein-coupled receptor GPR30. Annu Rev Physiol 2008;70:165-190
16. Prossnitz ER, Sklar LA, Oprea TI, Arterburn JB. GPR30: A novel therapeutic target in estrogen-related disease. Trends Pharmacol Sci 2008;29(3):116-123
17. Smith HO, Leslie KK, Singh M, et al. GPR30: A novel indicator of poor survival for endometrial carcinoma. Am J Obstet Gynecol 2007;196(4):386 e1-9. Discussion 386 e9-11
18. Filardo EJ, Graeber CT, Quinn JA, et al. Distribution of GPR30, a seven membrane-spanning estrogen receptor, in primary breast cancer and its association with clinicopathologic determinants of tumor progression. Clin Cancer Res 2006;12(21):6359-6366
19. Smith HO, Arias-Pulido H, Kuo DY, et al. GPR30 predicts poor survival for ovarian cancer. Gynecol Oncol 2009;114(3):465-471
20. Revised American Society for Reproductive Medicine classification of endometriosis. 1996. Fertil Steril 1997;67(5):817-821
21. Karita M, Yamashita Y, Hayashi A, et al. Does advanced-stage endometriosis affect the gene expression of estrogen and progesterone receptors in granulosa cells? Fertil Steril 2011;95(3):889-894
22. Kolkova Z, Noskova V, Ehinger A, Hansson S, Casslen B. G protein-coupled estrogen receptor 1 (GPER, GPR 30) in normal human endometrium and early pregnancy decidua. Mol Hum Reprod 2010;16(10):743-751
23. Plante BJ, Lessey BA, Taylor RN, et al. G Protein-Coupled Estrogen Receptor (GPER) Expression in Normal and Abnormal Endometrium. Reprod Sci 2012;19(7):684-693
24. Zeitoun KM, Bulun SE. Aromatase: A key molecule in the pathophysiology of endometriosis and a therapeutic target. Fertil Steril 1999;72(6):961-969
25. Noble LS, Simpson ER, Johns A, Bulun SE. Aromatase expression in endometriosis. J Clin Endocrinol Metab 1996;81(1):174-179
26. Zeitoun K, Takayama K, Michael MD, Bulun SE. Stimulation of aromatase P450 promoter (II) activity in endometriosis and its inhibition in endometrium are regulated by competitive binding of steroidogenic factor-1 and chicken ovalbumin upstreampromoter transcription factor to the same cis-acting element. Mol Endocrinol 1999;13(2):239-253
27. Zeitoun K, Takayama K, Sasano H, et al. Deficient 17beta-hydroxysteroid dehydrogenase type 2 expression in endometriosis: Failure to metabolize 17beta-estradiol. J Clin Endocrinol Metab 1998;83(12):4474-4480
28. Ferenczy A, Bertrand G, Gelfand MM. Proliferation kinetics of human endometriumduring the normal menstrual cycle. Am J Obstet Gynecol 1979;133(8):859-867
29. Felix JC, Farahmand S. Endometrial glandular proliferation and estrogen receptor content during the normal menstrual cycle. Contraception 1997;55(1):19-22
30. Kamat AA, Younes PS, Sayeeduddin M, Wheeler TM, Simpson JL, Agoulnik AI. Protein expression profiling of endometriosis: Validation of 2-mm tissue microarrays. Fertil Steril 2004;82(6):1681-1683
31. Taylor HS, Bagot C, Kardana A, Olive D, Arici A. HO X gene expression is altered in the endometriumof women with endometriosis. Hum Reprod 1999;14(5):1328-1331
32. Attia GR, Zeitoun K, Edwards D, Johns A, Carr BR, Bulun SE. Progesterone receptor isoform A but not B is expressed in endometriosis. J Clin Endocrinol Metab 2000;85(8):2897-2902
33. Ishihara H, Kitawaki J, Kado N, Koshiba H, Fushiki S, Honjo H. Gonadotropin-releasing hormone agonist and danazol normalize aromatase cytochrome P450 expression in eutopic endometrium from women with endometriosis, adenomyosis, or leiomyomas. Fertil Steril 2003;79(Suppl1):735-742
34. Pandey DP, Lappano R, Albanito L, Madeo A, Maggiolini M, Estrogenic PD. GPR30 signalling induces proliferation and migration of breast cancer cells through CTGF. EMBO J 2009;28(5):523-532
35. Zhang Z, Duan L, Du X, et al. The proliferative effect of estradiol on human prostate stromal cells is mediated through activation of ERK. Prostate 2008;68(5):508-516
36. Albanito L, Madeo A, Lappano R, et al. G protein-coupled receptor 30 (GPR30) mediates gene expression changes and growth response to 17beta-estradiol and selective GPR30 ligand G-1 in ovarian cancer cells. Cancer Res 2007;67(4):1859-1866
37. Vivacqua A, Bonofiglio D, Albanito L, et al. 17beta-estradiol, genistein, and 4-hydroxytamoxifen induce the proliferation of thyroid cancer cells through the g protein-coupled receptor GPR30. Mol Pharmacol 2006;70(4):1414-1423